• Journal of Radiation Industry
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• v.10 no.1
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• pp.7-12
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• 2016

Ikaros, a transcription factor containing zinc-finger motif, has known as a critical regulator of hematopoiesis in immune system. Ikaros protein modulates the transcription of target genes via binding to the regulatory elements of the genes promoters. However the regulatory function of Ikaros in other organelle except nuclear remains to be determined. This study explored radiation-induced modulatory function of Ikaros in cytoplasm. The results showed that Ikaros protein lost its DNA binding ability after LDIR (low-dose ionizing radiation) exposure. Cell fractionation and Western blot analysis showed that Ikaros protein was translocated into cytoplasm from nuclear by LDIR. This was confirmed by immunofluorescence assay. We identified Autotaxin as a novel protein which potentially interacts with Ikaros through in vitro protein-binding screening. Co-immunoprecipitation assay revealed that Ikaros and Autotaxin are able to bind each other. Autotaxin is a crucial enzyme generating lysophosphatidic acid (LPA), a phospholipid mediator, which has potential regulatory effects on immune cell growth and motility. Our results indicate that LDIR potentially regulates immune system via protein-protein interaction of Ikaros and Autotaxin.

• Journal of Applied Tourism Food and Beverage Management and Research
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• v.7
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• pp.139-164
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• 1997

Since the middle of 80's, foodservice industry has steadily developed, as the national income has been increased in correspondence with economic growth. We can figure that the improvement of culture life such as the improvement of culture life such as the conspicuous trend forward nuclear families, increasing double income family and the rate of holding car, has had something close to do with development of foodservice industry in the such economic development. Therefore, this study is to analyze foodservice industry playing an important role in the culture life and the influence of culture life improvement to foodservice industry, directly or indirectly, in accordance with the brilliant economic development in Korea.

• Journal of Energy Engineering
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• v.20 no.4
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• pp.267-277
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• 2011

The study looks at the development of new & renewable technology in a latecomer country, Korea. The main question is whether the development is driven by 'green demand' from the people or by the 'growth demand' from the industry. It also asks what are the characteristics of socio-technical constituency behind the development of new & renewable energy technology; growth-centered or environment-centered. It is found out that a 'New & renewable energy technology socio-techical constituency', consisted of NGOs, industry and government in the form of membership to New & Renwable Energy Policy Council of the government program, was established driving the development of new & renewable energy technology development in Korea. Yet, the coalition among them was based on 'the desire for growth' rather than 'the concern for environment'. The changes in authoritarian development state such as the adoption of governance approach to public decision-making process also contributed to the formation of the constituency.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.47-60
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• 2019

The purpose of this study is to explore the overall structural relationship between the statutory provisions of nuclear energy legislation and to identify the coherence of the nuclear law system using social network analysis. In particular, we analyze the legal structure of the "Nuclear Safety Act", which plays a central role in nuclear safety regulation, to examine the key provisions in legal network structure of Nuclear Safety Act. Therefore, we found the structural problems of the nuclear legal system and suggest the legislative improvement plan for reducing excessive legislative activity and determining the need for legal amendments in nuclear safety management and regulation. This study is expected to provide a analytical framework for making legal system of further policy in other science and technology industries as well as nuclear energy related industries.

• Nuclear Engineering and Technology
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• v.47 no.4
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• pp.454-460
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• 2015

Acoustic emission (AE) is one of the promising methods for detecting the formation of stress corrosion cracks (SCCs) in laboratory tests. This method has the advantage of online inspection. Some studies have been conducted to investigate the characteristics of AE parameters during SCC propagation. However, it is difficult to classify the distinct features of SCC behavior. Because the previous studies were performed on slow strain rate test or compact tension specimens, it is difficult to make certain correlations between AE signals and actual SCC behavior in real tube-type specimens. In this study, the specimen was a AISI 304 stainless steel tube widely applied in the nuclear industry, and an accelerated test was conducted at high temperature and pressure with a corrosive environmental condition. The study result indicated that intense AE signals were mainly detected in the elastic deformation region, and a good correlation was observed between AE activity and crack growth. By contrast, the behavior of accumulated counts was divided into four regions. According to the waveform analysis, a specific waveform pattern was observed during SCC development. It is suggested that AE can be used to detect and monitor SCC initiation and propagation in actual tubes.

• Journal of the Korean Society of Systems Engineering
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• v.12 no.1
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• pp.59-71
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• 2016

The Nuclear and Fossil Steam Turbines record a considerable number of failures annually. Some of these failures reported are as result of blade failure. The failure of the L-0 blade in a Steam Turbine is one of the most reported blade failure in Nuclear and Fossil steam turbines. This paper seeks to identify the best Non Destructive Evaluation (NDE) method or methods to be used in the steam turbine L-0 blades inspection process. The development of systems engineering processes presents an opportunity to apply NDE inspection to the L-0 blades. This process apply computer modelling of the L-0 using ANSYS and by simulating the stresses experienced by the L-0 blade during operation it is possible to identify the most susceptible areas for crack formation and growth. The results from these models compared to industry data for validation. The analysis of these results used to predict the most probable failure location and failure modes. Therefore NDE inspection can be applied to these areas with greater degree of accuracy. This would be beneficial in the increasing the accuracy in the detection of cracks and hence save inspection time and the overall inspection cost. Furthermore, not only the location for crack formation and NDE inspection determined but also best the NDE inspection technique/techniques to be applied appropriately on the L-0 blade are prescribed.

• Journal of Digital Convergence
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• v.13 no.12
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• pp.13-21
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• 2015

Ongoing advances in wireless broadband technologies can affect all of industrial society. As new wireless broadband technologies emerge, they will improve competition between established industries and their current services and produce new industries and new converged services. This paper analyzes the trend of next-generation wireless broadband and suggests ways of activating the industry further. To this end, we analyze the trend for previous wireless broadband industries and find out three influential factors (content, wireless network technology, and service) that will produce the continued growth of wireless broadband. Using these three factors, we propose a network technology-driven growth model. Based on that model, we offer activation plans for next-generation wireless broadband industries. This study thus provides an insightful perspective for next-generation wireless broadband industries by establishing additional useful guidelines for developing wireless broadband industries in the future.

• Proceedings of the KSME Conference
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• 2000.11a
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• pp.328-332
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• 2000

Following the method described in ASTM E1737, J resistance curves are measured for Cr-Mo steel SA387, and Cr steel A240 which are used as piping materials in nuclear industry. Crack driving force diagrams are generated in order to find out instability points in crack growth. The $J_{appl}$ curves, which are used in the crack driving force diagram, are obtained from EPRI J estimation method and the finite element analysis. Crack growth instability points are plotted in load-crack length plane and the results are discussed.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.129-134
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• 2014

Two series of SAHA-liked hydroxamate analogues were designed, synthesized and evaluated for their biological activities against nuclear HDACs. Compounds of Series I were found to be very effective inhibitors of cancer cell growth in the PC-3, Hut78, K562 and Jurkat E6-1 cancer cell lines with mean $IC_{50}$ values from $0.54{\mu}M$ (Ic, Jurkat E6-1) to $7.73{\mu}M$ (Ib, K562), indicating that they are cell permeable and the benzimidazolyl-based ligands are flexible enough to occupy the binding site of HDAC.

• Journal of the Korean Solar Energy Society
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• v.40 no.4
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• pp.23-33
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• 2020

The loss in photovoltaic power due to hailstorms has been highlighted as a major issue in the sustained growth of the PV power plant industry. This study investigates the safety of a solar module by conducting a numerical analysis of a hail test according to the IEC 61215 standard. Our study aims to elucidate the detailed behavior between the ice and solar modules and the micro-cracks forming on solar modules during hailstorms. To analyze the impact of hail, we used the ANSYS AUTODYN software to evaluate the impact characteristics on a solar module with different front glass thicknesses. The simulations show that a solar module with a glass thickness of 4.0 mm results in excellent durability against hail. The results indicate the feasibility of using simulations to analyze and predict micro-cracks on solar modules tailored to various conditions, which can be used to develop new solar modules.