• Proceedings of the KSME Conference
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• 2003.04a
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• pp.90-95
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• 2003

Fracture behaviors of pipes with local wall thinning are very important for the integrity of nuclear power plant. In pipes of energy plants, sometimes, the local wall thinning may result from severe erosion-corrosion (E/C) damage. However, the effects of local wall thinning on strength and fracture behaviors of piping system were not well studied. In this paper, the monotonic bending tests were performed of full-scale welded and unwelded carbon steel pipes with local wall thinning. A monotonic bending load was applied to straight pipe specimens by four-point loading at ambient temperature without internal pressure. The observed failure modes were divided into four types; ovalization, crack initiation/growth after ovalization, local buckling and crack initiation/growth after local buckling. Also, the strengths of welded and unwelded piping system with local wall thinning were evaluated.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2001.04a
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• pp.40-45
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• 2001

The relationship between structural geometry and number of life cycles to failure is investigated to improve the fatigue life of structural components. The linear elastic fracture mechanics(LEFM) approach is integrated with shape optimal design methodology. The primary objective of this study is to decide an optimal shape for enhancing the life of the structure. The results from LEFM analyses are used in the fatigue model to predict the life of the structure before failure is occurred. The shape of the structure is optimized by using the growth strain method. Relevant issues such as problem formulation, finite element modeling are explained. Three design examples are solved, and the results show that, with proper shape changes, the life of structural systems subjected to fatigue loads can be enhanced significantly.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.4
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• pp.234-247
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• 2018

The goal of nutrition of the preterm infant is to "provide nutrients to approximate the rate of growth and composition of weight gain for a normal fetus of the same postmenstrual age and to maintain normal concentrations of blood and tissue nutrients" (American Academy of Pediatrics 2014). Failure to provide the necessary amounts of all of the essential nutrients to preterm infants has produced not only growth failure, but also increased morbidity and less than optimal neurodevelopment. This continues to be true despite many efforts to increase nutrition of the preterm infants. In contrast, enhanced nutrition of very preterm infants, both intravenous and enteral, beginning right after birth, promotes positive energy and protein balance and improves longer term neurodevelopmental outcomes. The benefits are long lasting too, particularly for prevention of later life chronic diseases.

• Tunnel and Underground Space
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• v.8 no.2
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• pp.96-106
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• 1998

Rock contains discontinuities at all scales. These discontinuities make rock behave in a complex way. This paper discusses a new approach to underground design based on the theory of rock fracture mechanics. The mechanism of deformation and failure of coal was studied by observing the distributions of length, orientation and spacing of the pre-existing as well as stress-induced cracks. Different types of crack information. The crack information is dependent on the scale used. The cracks propagate along the intersections of the pre-existing cracks, and both extensile and shear crack growth occur depending on the direction of the load relative to the bedding planes. An analytical model that takes into account both shear and extensile crack growth was developed to predict the nonlinear stress-strain behavior of coal including strain-hardening and strain-softening.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.11a
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• pp.476-479
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• 2002

The ageing cause in many porcelain suspension insulators which occur on transmission and distribution line with dead-end stings is mechanical stress in interface between porcelain and cement materials. It is known that the principal mechanical stress which give electrical failure is the results of the displacement is due to cement growth. We studied the effect of cement displacement resulting environmental ageing parameters on porcelain insulator mechanical properties for transmission line by simulation (ANSYS/NASTRAN program) and test methods. These simulation analysis and experimental results show that cement volume growth affects severely to be mechanical failure ageing.

• Nuclear Engineering and Technology
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• v.46 no.1
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• pp.55-62
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• 2014

A method for estimating software reliability for nuclear safety software is proposed in this paper. This method is based on the software reliability growth model (SRGM), where the behavior of software failure is assumed to follow a non-homogeneous Poisson process. Two types of modeling schemes based on a particular underlying method are proposed in order to more precisely estimate and predict the number of software defects based on very rare software failure data. The Bayesian statistical inference is employed to estimate the model parameters by incorporating software test cases as a covariate into the model. It was identified that these models are capable of reasonably estimating the remaining number of software defects which directly affects the reactor trip functions. The software reliability might be estimated from these modeling equations, and one approach of obtaining software reliability value is proposed in this paper.

• The korean journal of orthodontics
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• v.53 no.6
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• pp.365-373
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• 2023

Objective: To investigate the potential correlation between fixed orthodontic retention failure and several patient- and treatment-related factors. Methods: Patients finishing treatment with fixed appliances between 2016 and 2017 were retrospectively included in this study. Those not showing fixed retention failure were considered as control group. Patients with fixed retention failure were considered as the experimental group. Additionally, patients with failure of fixed retainers in the period of June 2019 to March 2021 were prospectively identified and included in the experimental group. The location of the first retention failure, sex, pretreatment dental occlusion, facial characteristics, posttreatment dental occlusion, treatment approach and presence of oral habits were compared between groups before and after treatment separately by using a Fisher exact test and a Mann-Whitney U test. Results: 206 patients with fixed retention failure were included, 169 in the mandibular and 74 in the maxillary jaws. Significant correlations were observed between retention failure in the mandibular jaws and mandibular arch length discrepancy (P = 0.010), post-treatment growth pattern (P = 0.041), nail biting (P < 0.001) and abnormal tongue function (P = 0.002). Retention failure in the maxillary jaws was more frequent in patients with IPR in the mandibular jaws (P = 0.005) and abnormal tongue function (P = 0.021). Conclusions: This study suggests a correlation between fixed retention failure and parafunctional habits, such as nail biting and abnormal tongue function. Prospective studies with larger study populations could further confirm these results.

• Biomedical Science Letters
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• v.11 no.4
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• pp.421-427
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• 2005

To evaluate the diagnostic significance of p16 overexpression in human hepatocellular carcinoma (HCC), we analyzed p16 status and growth inhibitory patterns by p16 overexpression in HCC cell lines having different pRE status. SKHep1 and SNU449 cells show homozygous deletion of p16. The p16 gene in SNU398 cell is inactivated at posttranscription level. Adenovira1-p16 (Ad-p16) infection inhibits the cell growth in Hep3B, SNU398, and SNU449. Failure of growth inhibition in SKHepl results from the low transduction efficiency of adenovirus. The p16-mediated growth inhibition shows G 1 phase arrest in pRE-positive SNU449 but not in pRE-negative Hep3B. These results suggest that therapeutic efficacy of p16 gene might be considered on the transduction efficiency and the toxicity of adenoviral vector. Beside, growth inhibitory effect of p16 could be exerted through either pRE-dependent or -independent pathway.

• Clinical and Experimental Pediatrics
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• v.49 no.7
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• pp.703-709
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• 2006

Since the advent of growth hormone(GH), children with a wide variety of growth disorders have received GH treatment. In GH deficiency(GHD), Turner syndrome, chronic renal failure, children born small for gestational age, Prader-Willi syndrome, and idiopathic short stature, the therapeutic effects and safety profile of GH are reviewed. GH therapy has been clearly shown to improve height velocity and final adult height in a variety of pediatric conditions in which growth is compromised irrespective of GHD. Early initiation and individualization of GH treatment has the potential to normalize childhood growth. The supra-physiological doses of GH have been shown to increase height velocity during childhood and final height in non-GHD conditions. Adverse events during GH therapy are uncommon and often not drug related. However continued surveillance into adult life is crucial, especially in children receiving supra-physiological doses or whose underlying condition increases their risk of adverse effects.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.3 no.3
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• pp.79-85
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• 2004

The lightness of components required in automobile and machinery industry is requiring high strength of components. In particular, fatigue failure phenomena, which happen in metal, bring on danger in human life and property. Therefore, antifatigue failure technology takes an important part of current industries. Currently, the shot peening is used for removing the defects from the surface of steel and improving the fatigue strength on surface. Therefore, in this paper the effect of compressive residual stress of spring steel(JISG SUP-9)by shot peening on fatigue crack growth characteristics in stress ratio(R=0 1, R=0 3, R=0 6)was investigated considering fracture mechanics. By using the methods mentioned above, I arrived at the following conclusions: (1) The fatigue crack growth rate(da/dN) of the shot peening material was lower than the unpeening material And in stage I, ${\Delta}K_{th}$, the threshold stress intensity factor, of the shot peening material is high in critical parts unlike the unpeening material. (2) Fatigue life shows more Improvement in the shot peening material than in the unpeening material. And compressive residual stress of surface on the shot peening processed operate the resistance of fatigue crack propagation.