• 한국가축번식학회지
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• 제17권1호
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• pp.13-19
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• 1993

We investigated the effects of CP-2 extracted from the mixture of Copis and Croton tiglium L, which showed very high cytotoxic effect to the various tumor cells, on the growth and steroidenesis of primary and transformed cell lines PA-GS6 and PO-GRS1 by cotransfectionwith SV40 and Ha ras oncogenes. CP-2 inhibited the growth of PA-GS6 and PO-GRS1 in a dose dependent manner when the growth of them was measured by cell number and by protein content, while CP-2 did not affect the growth of primary granulose cells. Productions of progesterone ofprimary and transformed granulosa cells were stimulated by forskolin, but this stimulatory effect was blocked by treatment of CP-2. Clinical application of CP-2 asa new anti-cancer drug and utilization of transformed granulosa cells as a model system for the screening of anti-cancer drug were also discussed.

• East Asian Economic Review
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• 제23권1호
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• pp.3-26
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• 2019

This study investigates the effect of high-skilled inventor emigration rate on growth rate of the country of origin (COO). Inventor emigrants represent the human capital that can generate highly innovative work. The social network they form spurs knowledge diffusion and technology transfer back to their COOs, which in turn affects innovation and growth in their home countries. We run dynamic panel estimation for 154 countries during 1990-2011, and empirically show that a positive and statistically significant effect exists for the interaction of inventor emigration and trade. The result indicates that the direct negative impact of the brain drain can be mitigated by the positive feedback effect generated by the high-skilled inventor emigrants abroad. When coupled with an active trade policy that reinforces growth, countries can partially recoup the direct effect of the human capital loss. We stress the importance of international trade for successful technology transfer to occur, and offer insights for policies that can utilize the benefits of the rich social network of their high-skilled emigrants.

• 한국융합학회논문지
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• 제9권8호
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• pp.219-224
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• 2018

여포 상피세포에 우수한 모발성장 촉진효과를 보이는 minoxidil의 단점을 보완하고자 대체의학제재로서의 모발 성장 촉진제로 지모를 연구하였다. 지모과(知母科)의 뿌리식물인 지모(知母)는 해열제, 항 당뇨병, 항우울제, 항염제 등으로 이용되고 있는 한국의 전통적인 약용식물이다. 지모 에탄올 추출물을 마우스의 등에 도포하여 관찰하였는데 모든 그룹의 마우스에서 체중과 음식 섭취량은 유의한 차이를 보이지 않았다. 지모 에탄올 추출물은 혈청 조성의 변화 없이 왕성한 모발성장 촉진효과를 보임으로써 향후 모발성장 촉진제로서 유용한 가치가 있으리라 사료된다.

• 한국토양비료학회지
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• 제36권2호
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• pp.86-91
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• 2003

흑연이나 활성탄등의 탄소물질이 작물의 생육을 촉진하며 유용 토양미생물의 생육을 촉진하는것으로 알려져 있어 본 실험에는 제철공정에서 재활용, 정제된 흑연을 상토의 첨가제로 시용하여 벼의 생육과 수량에 미치는 영향에 대하여 실험하였다. 실험결과, 이앙기의 생육은 대조구와 비교하여 0.1% 흑연 첨가구에서 생육 촉진효과가 보였으며 이앙후 처리구별 생육의 차이는 그다지 보이지 않았다. 다만 0.1% 첨가구에서 육묘한 벼의 수량은 특별한 통계적 유의성을 보이지 않았으나 약 1%정도 증수되었다.

• 한국약용작물학회지
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• 제20권2호
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• pp.108-116
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• 2012

In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing $Rosa$ $mutiflora$ roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP ($125.0{\pm}4.9\;FU/cm^2$) compared to before treatment ($104.3{\pm}4.7\;FU/cm^2$, p < 0.05), and hair thickness were also significantly increased ($0.066{\pm}0.003$ mm) than before treatment ($0.055{\pm}0.002$ mm, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with $1.23{\pm}0.05$ (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

• 한국주조공학회지
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• 제5권4호
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• pp.258-270
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• 1985

The structures and mechanical properties of undirectionally solidified Sn-Zn eutectic alloys have been examined over the growth range 7mm/h to 6,000mm/h. The structures of unidirectionally solidified Sn-Zn eutectic alloys were primarily broken-lamellar at growth rates below 760mm/h and became fibrous at higher growth rates above that. At a growth rate 3,084mm/h the structures were fibrouse only. There is no dendrites at any growth rates, but occasionally ribbon-like morphologies were seen. The under cooling increased parabolically with growth rate increase. The hardness of specimes increased with growth rates increase but heat-treated specimen decreased after growth rates 760mm/h and became constant value. The effect of heat-treatment was good at lower growth rate. At room temperature tensile strength increased with growth rates up to R=990mm/h and then tensile strength became near-constant value. The effect of heat-treatment was well at lower growth rate.

• KDI Journal of Economic Policy
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• 제42권3호
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• pp.1-32
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• 2020

This paper studies urban growth in Korean cities. First, I document that population growth patterns change over time and that the current population distribution supports random urban growth. I confirm two empirical laws-Zipf's law and Gibrat's law-both of which hold in the period of 1995-2015, but do not hold in the earlier period of 1975-1995. Second, I find a systematic employment growth pattern of Korean cities in spite of the random population growth. I examine market access effects on employment growth. Market access, a geographical advantage, has a significant influence on urban employment growth. The market access effect is higher in the Seoul metropolitan area than in the rest of the country. This effect is stronger on employment growth in the manufacturing industry compared to employment growth in the service industry. These results are robust with various checks (e.g., different definitions of urban areas). The results here suggest that policymakers should consider geographical characteristics when they make policy decisions with respect to regional development.

• 한국재료학회지
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• 제27권11호
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• pp.609-616
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• 2017

We investigated a Leidenfrost effect in the growth of ZnO nanostructures on silicon substrates by ultrasonic-assisted spray pyrolysis deposition(SPD). Structural and optical properties of the ZnO nanostructures grown by varying the growth parameters, such as substrate temperature, source concentration, and suction rate of the mist in the chambers, were investigated using field-emission scanning electron microscopy, X-ray diffraction, and photoluminescence spectrum analysis. Structural investigations of the ZnO nanostructures showed abnormal evolution of the morphologies with variation of the substrate temperatures. The shape of the ZnO nanostructures transformed from nanoplate, nanorod, nanopencil, and nanoprism shapes with increasing of the substrate temperature from 250 to $450^{\circ}C$; these shapes were significantly different from those seen for the conventional growth mechanisms in SPD. The observed growth behavior showed that a Leidenfrost effect dominantly affected the growth mechanism of the ZnO nanostructures.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2002년도 추계학술대회 논문집
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• pp.73-78
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• 2002

Ships and ocean structures are generally under random loading. Various type of variable-amplitude loading affects fatigue crack growth and fatigue life. However interaction effects due to irregularity of loading including random loading have not explained exactly and it is difficult to examined fatigue crack growth behaviour and fatigue life for this reason. Therefore in this paper crack growth tests with constant-amplitude loading including a single overload were conducted to measure plastic zone size near crack tip of DENT specimen. And the observed plastic zone sized were discussed in terms of crack growth rate. As a result of this the effect the plastic rue size due to the overload is examined on the effect on crack growth rate and, consequently, fatigue life.

• 한국환경복원기술학회지
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• 제7권2호
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• pp.1-11
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• 2004

The purpose of this study was to determine usability as potted flowers and garden plants by controlled plant height using growth retardants. There was no significant difference on the dwarfing effect according to the degree of exposure the sun, but growth was well under full exposure to the sun. The plant height was decreased by application of Cycocel (CCC), Bonzi (paclobutrzol), Ancymidol, and Uniconazole compared to the control group, and treatment of Bonzi $5mg{\cdot}L^{-1}$ was most dwarfing effect for both full sun exposure or 70% controlled shading condition. No consistent different was found in stem diameter, leaf color change, the content of chlorophyll and anthocyanin when the concentration of plant growth retardants was altered. These factors were affected only by light intensity. In comparison to the results of the control group, leaf length, leaf width, plant width and petiole length were all reduced by the application of growth retardants.