• Title/Summary/Keyword: Growing teratoma syndrome

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Metastatic Mature Teratoma and Growing Teratoma Syndrome in Patients with Testicular Non-Seminomatous Germ Cell Tumors

  • Daniel B. Green;Francisco G. La Rosa;Paul G. Craig;Francesca Khani;Elaine T. Lam
    • Korean Journal of Radiology
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    • v.22 no.10
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    • pp.1650-1657
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    • 2021
  • Metastatic mature teratoma is a common radiologic and histopathologic finding after chemotherapy for metastatic non-seminomatous germ cell tumors. The leading theory for these residual tumors is the selective chemotherapy resistance of teratomas versus the high chemotherapy sensitivity of the embryonal components. Growing teratoma syndrome is a relatively rare phenomenon defined as an enlarging residual mass histologically proven to be a mature teratoma in the setting of normal serum tumor markers. Metastatic mature teratomas should be resected because of their malignant potential and occasional progression to growing teratoma syndrome with the invasion of the surrounding structures. CT is the preferred imaging modality for post-chemotherapy surveillance and should cover all sites of potential metastatic disease. This article reviews the clinical, pathologic, and multimodality imaging features of metastatic mature teratomas in patients with primary testicular non-seminomatous germ cell tumors.

Treatment of Mediastinal Growing Teratoma Syndrome - A case report - (종격동에 발생한 성장 기형종 증후군(Growing Teratoma Syndrome)의 치험 -1예 보고-)

  • Cho Jong Ho;Son Ho Sung;Jo Won Min;Min Byoung Ju;Lee In Sung;Shin Jae Seung
    • Journal of Chest Surgery
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    • v.38 no.10 s.255
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    • pp.729-732
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    • 2005
  • A 15-year-old male was admitted with right-sided chest pain and cough for one month. On chest computed tomographic scan, a $10\times15\times16$ em-sized huge mediastinal mass was occupied in the right hemithorax. Radiologically, it seemed that the tumor was severely adhesive on the heart and the superior vena cava. Therefore we decided on chemotherapy and radiotherapy first instead of surgery. The tumor marker was nearly normalized afterwards, but the tumor size was seemed to be bigger on chest tomographic scan. This suggests the growing teratoma syndrome. After the successful resection, he showed symptomatic improvement and is being followed up without any symptoms in an out patient department up to now.