• Journal of the Korean Institute of Landscape Architecture
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• v.25 no.4
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• pp.1-17
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• 1998

Most of the tourist resort facilities in our country cannot be used in the winter season, and only a few spa resorts and sky resorts are available in the winter. To ameliorate this problem, various types of winter resort facilities have been constructed since 1970s and the massive development of winter resort facilities changed the resort market from a seller's market to a buyer's market. There has been however,few researches on marketing strategies for winter resorts, and there is a growing need for a rational method to maximize tourists' satisfaction and developers'profit at the same time. This research aims to develop a positining strategy to engance the marketability of winter resorts by classifying the resort market with the self-image types of users, and by analyzing the structure of the market, users' preferences, and locational factors. A survey was conducted with cases of Yong-Pyung resort, Mu-Ju resort, Alps resort, Bears resort, Back-Am spa resort, Su-An-Bo spa resort, and I-Chon spa resort. A list of questions in five categories -- similarity, characteristics, preferences, self-image, and personal characteristics of the respondents -- was constructed and tested. Among the 750 copies of questionnaire distributed, 700 were returned by only 378 were analyzed after screening missing or reckless answers. The statistical analysis of the data were conducted using techniques of correlation analysis, frequency analysis, factor analysis. Factor analysis and cluster analysis were used to group the cluster of self-image and a discriminant analysis were used to confirm this classification. The demographical characteristics were identified by frequency analysis, and resorts attributes were analyzed by oneway ANOVA analysis. Multidimensional scaling methods such as KYST, PROFIT, and PREFMAP were used for the positioning strategy.

• Journal of Veterinary Clinics
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• v.18 no.4
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• pp.324-328
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• 2001

This study was performed to evaluate the effects of $AS_2O_3$ upon antiangiogenesis in rat cornea, to examine it\`s possible application as an anticancer drug and to provide basic data for further studies of antiangiogenetic mechanism of $AS_2O_3$ . Angiogenesis was induced by cornea micropocket assay, as previously described. Sixteen of forty-eight eyes of Sprague-Dawley rats were randomly assigned to one of three groups, namely, only a bFGF group(control group), and a group treated by $AS_2O_3$ ($AS_2O_3$ group). After pellet implantation, we measured the number of new vessels, vessel length and clock hour of neovascularization, and area of neovascularization was determined using a mathematical formula. New vessels growing began at day 3, number of vessels in $AS_2O_3$ group were significantly more less than those in control group (p<0.05). The length of vessels of $AS_2O_3$ group was significantly shorter than that of control group after day 3(p<0.05). The clock hours of all group were slowly increased at all days but $AS_2O_3$ group was inhibited more than control group. Neovascularization areas of $AS_2O_3$ group were more significantly inhibited than those of control group (p<0.05). This study showed that $AS_2O_3$ had powerful antiangiogenetic effects and it would be useful in the choice of anticancer drug.

• Journal of Fashion Business
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• v.10 no.2
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• pp.194-206
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• 2006

With the change of social paradigm, the number of child care facilities is increasing and, accordingly, demand for sportswear for preschool children is also growing. Considering this trend, the present study purposed to subdivide the preschooler' sportswear market, which is currently using uniform design, and diversify the images of preschoolers' sportswear utilizing information on preschoolers' sportswear market, to produce high-quality sportswear of reasonable price, and to induce the development of various materials and designs. The results of this study are as follows. First, according to the result of paired t-test on the current image of preschoolers' sportswear and its future image to be promoted, among 22 items of sportswear image, the scores of comfortable and active images were highest. According to the results of factor analysis, five factors were identified, and kindergarten directors gave the highest score to plain image for preschoolers' sportswear and the lowest score to elegance image. This suggests that there should be active and diverse approaches to sportswear design. When the mean score of factors was compared among preschoolers' sportswear image to be promoted in the future, high-class elegant image got the highest score and was followed by functional image. In addition, lively and neat image got the lowest score. Second, when we analyzed the correlations between the five factors of image identified through factor analysis and three groups formed through cluster analysis in order to classify buyers based on the current images of preschoolers' sportswear and future images to be promoted, kindergarten directors were found to emphasize functional image currently in selecting sportswear for their children but to promote elegant image for future sportswear.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.4
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• pp.763-774
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• 2016

Companies have recently become interested in the importance of long-term relationships with customers because business-based marketing ideas of the past have evolved into long-term relationship-based marketing. Establishing a relationship with customers to a company is not a simple method to form a market of consumers and provider; it is now understood as an important factor directly connected to the survival of a company. This study is to help Korean fashion brands in China build an efficient strategy for sales promotion and loyal customers through the analysis of the effect of familiarity with Korean fashion brands on satisfaction and brand loyalty in a rapidly growing Chinese fashion market. An online questionnaire covering Korean fashion brands in China was completed by 377 Chinese male and female customers aged 20 to 39 years old from March 20 to March 27, 2014. Data analysis was performed by factor analysis and path analysis using SPSS 20.0 and AMOS. Both direct experiences and indirect experiences influenced brand familiarity. It showed that brand familiarity had a significant direct effect and an indirect effect through satisfaction on brand loyalty. A competitive advantage in the present Chinese fashion market requires that loyalty builds and that brand loyalty increases by creating a long-term relationship with customers when familiarity about the brand is induced.

• Food Science and Biotechnology
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• v.18 no.5
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• pp.1063-1070
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• 2009

Dangyuja (Citrus grandis Osbeck) is a native plant growing only on Jeju Island in Korea. In this study, antiinflammatory effect of dangyuja leaves on a murine macrophage cell line was investigated. RAW 264.7 murine macrophage cells were stimulated with lipopolysaccharide (LPS, $1{\mu}g/mL$) to induce expression of pro-inflammatory markers [interleukin (IL)-6 and inducible nitric oxide synthase (iNOS)]. The crude extract (80% MeOH Ex.) and solvent fractions (hexane, $CHCl_3$, EtOAc, BuOH, and $H_2O$ Ex.) were obtained from dangyuja leaves. The $CHCl_3$ fraction inhibited the nitric oxide (NO) and IL-6 production in a dose-dependent manner. Also, the $CHCl_3$ fraction inhibited mRNA expression and protein levels of iNOS in a dose-dependent manner. Furthermore, the $CHCl_3$ fraction inhibited LPS-induced nuclear factor (NF)-${\kappa}B$ activation and phosphorylation of mitogen-activated protein kinases (MAPKs: ERK, JNK, and p38). These results suggest that dangyuja leaves may inhibit LPS-induced production of inflammatory markers by blocking NF-${\kappa}B$ and MAPKs signaling in RAW 264.7 cells.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.1
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• pp.59-70
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• 2008

Purpose: We evaluated the therapeutic effect of AEE788, a dual inhibitor of epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinases on human salivary adenoid cystic carcinoma (ACC) cells growing in nude mice. Experimental Design: We examined the effects of AEE788 on salivary ACC cell growth and apoptosis. To determine the in vivo effects of AEE788, nude mice with orthotopic parotid tumors were randomized to receive oral AEE788 (50 mg/kg) three times per week, injected paclitaxel ($200{\mu}g$) once per week, AEE788 plus paclitaxel, or placebo. Mechanisms of in vivo AEE788 activity were determined by immunohistochemical analysis. Results: Treatment of salivary ACC cells with AEE788 led to growth inhibition and induction of apoptosis. AEE788 inhibited tumor growth and prevented lung metastasis in nude mice. Furthermore, AEE788 potentiated growth inhibition and apoptosis of ACC tumor cells mediated by paclitaxel. Tumors of mice treated with AEE788 and AEE788 plus paclitaxel exhibited down-regulation of activated EGFR and its downstream mediators (Akt and MAPK), increased tumor and endothelial cell apoptosis, and decreased microvessel den-sity, which correlated with a decrease in the level of MMP-9, MMP-2 and bFGF expression and a decrease in the incidence of vascular metastasis. Conclusions: These data show that tumor-associated endothelial cells are important in the process of tumor-metastasis. And VEGFR can be a molecular target for therapy of metastatic lung lesion of salivary ACC.

• Journal of Digital Convergence
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• v.13 no.3
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• pp.1-10
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• 2015

Carrier billing services market is growing according to the technical development. This study investigated the limiting factor in carrier billing services and suggested the improvement factor for it using the Delphi Method. The amount money to use in carrier billing charges should be provided in their credit based and the accumulated payment using a text message is displayed and also telecommunications carriers and carrier billing firms are the least responsible for consumer harm. It also provides administrative responsibility for communications carriers and billing services company for non recognition and payment. The service provider to prove negligence not proven by consumer and telecommunications billing service delinquency rate is applied at a rate such as a credit card and it also should integrate retail payment and service fee. This study will contribute to the communication billing services market growth through improved communication billing service. Further research is needed to continue the study of the factors that emerged from communication and billing services due to emerging technologies and services.

• Molecules and Cells
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• v.43 no.7
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• pp.645-661
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• 2020

Leaf senescence is a developmental process by which a plant actively remobilizes nutrients from aged and photosynthetically inefficient leaves to young growing ones by disassembling organelles and degrading macromolecules. Senescence is accelerated by age and environmental stresses such as prolonged darkness. Phytochrome B (phyB) inhibits leaf senescence by inhibiting phytochrome-interacting factor 4 (PIF4) and PIF5 in prolonged darkness. However, it remains unknown whether phyB mediates the temperature signal that regulates leaf senescence. We found the light-activated form of phyB (Pfr) remains active at least four days after a transfer to darkness at 20℃ but is inactivated more rapidly at 28℃. This faster inactivation of Pfr further increases PIF4 protein levels at the higher ambient temperature. In addition, PIF4 mRNA levels rise faster after the transfer to darkness at high ambient temperature via a mechanism that depends on ELF3 but not phyB. Increased PIF4 protein then binds to the ORE1 promoter and activates its expression together with ABA and ethylene signaling, accelerating leaf senescence at high ambient temperature. Our results support a role for the phy-PIF signaling module in integrating not only light signaling but also temperature signaling in the regulation of leaf senescence.

• Korean Journal of Human Ecology
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• v.21 no.4
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• pp.781-790
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• 2012

In midst of growing interest and awareness towards sustainability and being "green", there has been increased demand for sustainable clothing. In the purpose of boosting eco-friendly textiles industry, this research was conducted by investigating environmentally-conscious clothing behavior of university students and assessing their views on eco-friendliness of fibers. Thus, their awareness on recycled polyester fiber was evaluated. The research was conducted by surveying 257 university students residing in Daejeon. The data were analyzed with descriptive statistics, factor analysis, and reliability analysis, using SPSS 19.0. The results were as follows. 1) The majority of the subjects answered "Disposing clothing in the clothing recycling container" to reduce environmental impact. 2) Six factors of eco-friendliness of fiber were extracted as reutilization, unfinishedness, economics, environment preservation, natural materials, and slow fashion by using factor analysis. 3) Subjects scored organic cotton as most eco-friendly among various fibers. Recycled polyester fiber was graded less sustainable than natural fiber, but more eco-friendly than artificial one. 4) In assessment of subject's awareness of recycled polyester fiber, they highly valued on resource-reutilization and economics, but less valued on its hygiene, thermal insulation and health-functionality.

• The Journal of the Korea Contents Association
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• v.20 no.1
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• pp.217-232
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• 2020

The purpose of this study is to organize prior research related to e-commerce activation factors available to stakeholders in the online distribution industry, and to conduct FGI with e-commerce experts to calculate the importance of each factor in order based on the 3 Level Service Model of Kwon Hyeog-in (2010), the key factors derived through the preceding study and the FGI were structured and the weighting of each factor was derived using AHP methodology. In the higher factors, the private sector (0.542) > communes (0.237) > public (0.2222) appeared to be important. Sub-factories included 'search service development' (0.0970)', 'recommendation service development (0.0805)', 'consumer needs analysis (0.0534)', 'consumer consumption pattern analysis (0.0505)' and 'other platform-linked service development (0.0450)', in the order of weighting down, indicating each of the factors within the top 15 priority. The results of this study will be utilized throughout the e-commerce industry as well as e-commerce enterprises, providing an academic foundation for the rapidly growing e-commerce ecosystem.