• Title/Summary/Keyword: Growing factor

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Effects of Intra-duodenal Infusion of Limiting Amino Acids on Plasma Insulin-like Growth Factor I, Growth Hormone, Insulin and Liver Insulin-like Growth Factor I mRNA in Growing Goat Fed a Maize Stover-based Diet

  • Sun, Z.H.;Tan, Z.L.;Yao, J.H.;Tang, Z.R.;Shan, J.G.;Hu, J.P.;Tang, S.X.;Jiang, Y.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.733-741
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    • 2007
  • The effects of intra-duodenal infusion of methionine (Met), lysine (Lys) and leucine (Leu) on dry matter intake (DMI), the concentrations of insulin-like growth factor I (IGF-I), growth hormone (GH) and insulin in plasma, and liver IGF-I mRNA level were investigated in two experiments for Liuyang Black growing wether goats. In Experiment 1, three goats ($10.0{\pm}0.1$ kg) were fitted with ruminal, proximal duodenal and terminal ileal fistulaes to determine the infusion amounts of Met, Lys and Leu at the duodenum according to essential amino acid flows into the duodenum and their apparent digestibility. The infusion amounts were 0.77 g/d, 0.91 g/d and 0.58 g/d respectively. In Experiment 2, 4 groups of goats (($10.0{\pm}0.2$ kg) for each group, were cannulated at the duodenum, and were infused with a mixture of Met, Lys and Leu (Control), or mixtures with 21% Met, Lys or Leu replaced with glutamate respectively on a nitrogenous basis. The replacement of 21% Met, Lys or Leu with glutamate did not affect intakes of maize stover, concentrate or both (p>0.05) when compared with the control. The replacement of 21% Met or Lys significantly (p<0.05) reduced plasma GH, insulin and IGF-I concentrations and liver IGF-I mRNA level. The replacement of 21% Leu with glutamate reduced (p<0.05) plasma IGF-I concentration only, but not plasma insulin and GH, as well as liver IGF-I mRNA level (p>0.05). The close relationships between supplying Met and Lys in the lumen of the duodenum and plasma IGF-I, GH and insulin concentrations, as well as liver IGF-I mRNA level in this study indicate that the effects of the limiting amino acids on nutrition of animals are likely intermediated via their effects on these hormones, and these hormone profiles could be used as intermediate markers for the limiting order of amino acids.

The effects of indomethacin on distribution and expression of COX-2 and IGF-I in the mandibular condyle of growing dogs (인도메타신투여가 개의 하악두에서 COX-2와 IGF-I의 발현과 분포에 미치는 영향)

  • Nam, Jong-Hyun;Lee, Ki-Soo;Kang, Yoon-Goo
    • The korean journal of orthodontics
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    • v.35 no.5 s.112
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    • pp.351-360
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    • 2005
  • This study aimed to investigate the effects of indomethacin on distribution and expression of COX-2 and IGF-1 in the mandibular condyle ofi growing dogs and to examine the number of chondroclasts around the mineralization zone indomethacin inhibits prostatlandin $E_2$ production in the tissue by inhibiting synthesis of cyclooxygenase 2. Prostaglandin $E_2$ stimulates insulin-like growth factor synthesis. Insulin-like growth factor stimulates growth of mandibular condylar cartilage. Eight mongrel dogs. aged 13-14 weeks, were divided into 4 groups. Group 1 and group 2 were administered indomethacin 2 mg/Kg/day orally two times a day for 7 days and 14 days respectively. Group 3 were administered indomethacin 8mg/Kg/day orally 2 times a day for 14 days, and 4he control group were administered a placebo. The mandibular condyle heads were sectioned in $5{\mu}m$ thickness The specimens were stained with H-E staining. COX-2 immunohistochemical staining and IGF-1 immunohistochemical staining and examined under microscope. After TRAP staining, the number of chondroclasts were calculated The observed results were as follows: Indomethacin inhibited expression and distribution of COX-2 and IGF-1 on the proliferative zone of condylar cartillage. Indomethacin decreased the number of chondroclastes on the mineralization zone by a time-dependent manner (P<0.05). Indomethacin inhibited expression and distribution of IGF-I by a dose and time-dependent manner. These results show that indomethacin inhibited expression and distribution of COX-2 and IGF-1 on the proliferative zone of condylar cartilage and decreased the number of chondroclasts and suggests that when indomethacin is administered for a long time, condyle growth could be delayed.

Quantitative Taxonomic Studies on the Group of Salix pseudo-lasiogyne Growing in Korea (한국산(韓國産) 능수버드나무류(類)의 수량적(数量的) 분류(分類)에 관(關)한 연구(硏究))

  • Kim, Eun Shik;Lee, Tchang Bok
    • Journal of Korean Society of Forest Science
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    • v.59 no.1
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    • pp.1-8
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    • 1983
  • Classification on the group of Salix pseudo-lasiogyne growing in Korea, was conducted using cluster analysis, factor analysis, and principal component analysis. Thirty-six characters(Table 2) of the 5 basis species were measured. The phenograms and ordination plot showing the relationships between the species were made by applying the cluster analysis and principal component analysis. Five important factors, such as leaf blade width, number of right serration, angle of leaf apex, number of flowers in an ament, and the ratio of petiole length to width, were inferred from the rotated factor matrix, and their state values were presented in polygonal diagram. Salix pseduo-lasiogyne and S. babylonica were similarly correlated and linked in one group, S. dependens and S. matsudana for tortuosa were secondarily linked in the other group. S. koreensis appeared as an aliemated species from each of the two groups.

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A Role for Ginseng in the Control of Postprandial Glycemia and Type 2 Diabetes

  • Vuksan Vladimir;Sievenpiper John L;Xu Zheng;Zdravkovic Uljana Beljan;Jenkins Alexandra L;Arnason John T;Bateman Ryon M.;Leiter Lawrence A;Josse Robert G;Francis Thomas;Stavro Mark P
    • Proceedings of the Ginseng society Conference
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    • 2002.10a
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    • pp.1-19
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    • 2002
  • The use of herbals has increased considerably while their efficacy and safety remain untested. This unsupported surge in demand has prompted a call for their clinical evaluation. One area in which evaluations are emerging is ginseng and diabetes. Growing evidence is accumulating from in vitro and animal models indicating that various ginseng species, American (Panax quinquefolius L), Asian (Panax ginseng C.A. Meyer), Korean Red, San-chi (Panax notoginseng [Burk.] P.R. Chen), and the non-panax species Siberian (Eleutherococcus senticossus) ginsing, and their fractions, saponins (ginsenosides) and peptidoglycans (panaxans for panax species and eleutehrans for Siberian ginseng), might affect carbohydrate metabolism and related signaling molecules. Recent human studies from our laboratory have also shown a blood glucose lowering effect of American ginseng (AG) and some other ginseng spices postprandially after acute administration and chronically after administration for 8-weeks in people with type 2 diabetes. Although generally encouraging, these data only indicate a need for more evaluations of ginsengs safety and efficacy. Because of poor industry standardization, it is not known whether all ginsengs will affect blood glucose. In this regards some ginseng batches have demonstrated null effects while others have even raised postprandial glycemia. Clinical research should therefore focus on components involved in its glucose lowering effects.

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A Study on the Influence of Franchise PC Game Rooms Store Attributes on Store Selection Behavior (프랜차이즈 피씨방 점포선택속성이 점포선택행동에 미치는 영향)

  • Seong, Baiksoon
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.11 no.3
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    • pp.231-240
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    • 2015
  • This study empirically analyzed the relationship between the franchise pc game rooms selection behavior and revisit, recommendations. Select Properties from the franchise pc game rooms store is ease of access, computer specifications, pleasant environment, brand power and pricing strategy. Korean franchise industry is in spite of the short history of just over 30 years growing very fast. Especially pc game rooms store is 14,782 in 2012 years, pc game rooms store is operated by franchise form 10.6%, 87.9% operated by private, co-operation was confirmed at 1.5%. Conclusions are as follows. First, factors that significantly affect the degree of revisit has been identified as computer specifications, pleasant environment, brand power. Second, the recommendation is an important factor of the computer specifications, brand power, pricing strategy. Finally, franchise pc game rooms successful strategy has excellent computer's specifications, it needs a promotion strategy to attract pc game tournaments to be notified of brand power. We can also see that running is an important factor in a pleasant environment and a flexible pricing strategy.

A Study on a Packet Forwarding Scheme based on Interworking Architecture (연동 구조 기반의 패킷 포워딩 기법에 대한 연구)

  • Kim, Seok-Hoon;Ryoo, In-Tae
    • Journal of Internet Computing and Services
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    • v.6 no.3
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    • pp.97-106
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    • 2005
  • Generally, network QoS is determined by timeliness, bandwidth, and reliability, As IT technologies are growing day by day, the bandwidth and reliability factors are expected to be able to satisfy user's requirements. The timeliness factor, however, has not fully met user's requirements yet. In this paper, we propose a packet forwarding scheme named POSIA (Packet forwarding Scheme based on Interworking Architecture) that can provide quite a good QoS (quality of service) by minimizing processing time which is the major part of the timeliness factor. Based on path and resource reservation mechanism, the proposed POSIA makes routers on the packet forwarding path synchronize with each other and then forward packets, The POSIA has been verified to outperform the existing MPLS packet forwarding scheme through computer simulations using OPNET.

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Enhancing Medical Images by New Fuzzy Membership Function Median Based Noise Detection and Filtering Technique

  • Elaiyaraja, G.;Kumaratharan, N.
    • Journal of Electrical Engineering and Technology
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    • v.10 no.5
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    • pp.2197-2204
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    • 2015
  • In recent years, medical image diagnosis has growing significant momentous in the medicinal field. Brain and lung image of patient are distorted with salt and pepper noise is caused by moving the head and chest during scanning process of patients. Reconstruction of these images is a most significant field of diagnostic evaluation and is produced clearly through techniques such as linear or non-linear filtering. However, restored images are produced with smaller amount of noise reduction in the presence of huge magnitude of salt and pepper noises. To eliminate the high density of salt and pepper noises from the reproduction of images, a new efficient fuzzy based median filtering algorithm with a moderate elapsed time is proposed in this paper. Reproduction image results show enhanced performance for the proposed algorithm over other available noise reduction filtering techniques in terms of peak signal -to -noise ratio (PSNR), mean square error (MSE), root mean square error (RMSE), mean absolute error (MAE), image enhancement factor (IMF) and structural similarity (SSIM) value when tested on different medical images like magnetic resonance imaging (MRI) and computer tomography (CT) scan brain image and CT scan lung image. The introduced algorithm is switching filter that recognize the noise pixels and then corrects them by using median filter with fuzzy two-sided π- membership function for extracting the local information.

Study of Peak Load Demand Estimation Methodology by Pearson Correlation Analysis with Macro-economic Indices and Power Generation Considering Power Supply Interruption

  • Song, Jiyoung;Lee, Jaegul;Kim, Taekyun;Yoon, Yongbeum
    • Journal of Electrical Engineering and Technology
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    • v.12 no.4
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    • pp.1427-1434
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    • 2017
  • Since the late 2000s, there has been growing preparation in South Korea for a sudden reunification of South and North Korea. Particularly in the power industry field, thorough preparations for the construction of a power infrastructure after reunification are necessary. The first step is to estimate the peak load demand. In this paper, we suggest a new peak demand estimation methodology by integrating existing correlation analysis methods between economic indicators and power generation quantities with a power supply interruption model in consideration of power consumption patterns. Through this, the potential peak demand and actual peak demand of the Nation, which experiences power supply interruption can be estimated. For case studies on North Korea after reunification, the potential peak demand in 2015 was estimated at 5,189 MW, while the actual peak demand within the same year was recorded as 2,461 MW. The estimated potential peak demand can be utilized as an important factor when planning the construction of power system facilities in preparation for reunification.

The Human Capital as a Factor of Competitiveness and Economic Development

  • Chulanova, Zaure K.
    • Asian Journal of Business Environment
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    • v.7 no.3
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    • pp.23-31
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    • 2017
  • Purpose - The purpose of this paper is to rationale the new approach to analysis of the human capital as a factor of effective development of a national economy and increase the level of country's competitiveness. Research design, data, and methodology - This research aims the furthest development of the conception in human capital formation. The study made on the base of the methods with scientific classification and systematization, that is, comparative, statistical analysis, economic-mathematic method, and expert assessment and ratings. Results - This research attempted to measure the correlation between the human capital elements and the level of country's competitiveness. The study revealed that formation of the competitive human capital cannot be considered in separation from the development and modernization of education system, the improvement of employment sphere, and the creation of effective interaction between them through the system of professional skills. Conclusions - The competitive human capital formation is one of the most important goals in the innovative economy construction and modern development, and it is also indispensable subject. Especially in the condition of economic crises, the necessity of formation and development of the effective human capital is considerably increasing. Realization of this task requires the development and stimulation of all the factors influencing the growing human potential.

The Guideline structure for improving sustainability in building construction projects (건축 프로젝트의 친환경성 제고를 위한 사업관리 가이드라인 구성 체계 도출)

  • Hong, Suk-Kyoo;Kim, Chang-Won;Cho, Hunhee;Kang, Kyung-In
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2014.05a
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    • pp.26-27
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    • 2014
  • Sustainable development has become a growing concern throughout the world. Construction industry also has participated in the efforts to minimize the environmental impacts. In Korea, the government has already established the green construction certification(G-seed) and guidelines for sustainable construction. However, domestic guidelines are focused on the design and construction phase, not on the construction project. In addition, it is difficult to find instructions due to the complex structure based on the work unit. Therefore this study aims to deduct the component structure for sustainable construction guidelines in the planning, design and construction phases by utilizing the Factor Analysis. Following the literature review, a total of 26 criteria were identified. Further, a survey was conducted to capture the perceptions on the importance of the criteria. According to the factor analysis, the criteria can be grouped into 8 factors : Environmental factors management, Management planning, Cost and Design management, Energy management, Material management, Certification and regulation management, General Management and Others.

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