• Title/Summary/Keyword: Group decisions

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Comparison of the Efficacy and Safety of EFGR Tyrosine Kinase Inhibitor Monotherapy with Standard Second-line Chemotherapy in Previously Treated Advanced Non-small-cell Lung Cancer: a Systematic Review and Meta-analysis

  • Qi, Wei-Xiang;Shen, Zan;Lin, Feng;Sun, Yuan-Jue;Min, Da-Liu;Tang, Li-Na;He, Ai-Na;Yao, Yang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5177-5182
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    • 2012
  • Purpose: To compare the efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitormonotherapy (EFGR-TKIs: gefitinib or erlotinib) with standard second-line chemotherapy (single agent docetaxel or pemetrexed) in previously treated advanced non-small-cell lung cancer (NSCLC). Methods: We systematically searched for randomized clinical trials that compared EGFR-TKI monotherapy with standard second-line chemotherapy in previously treated advanced NSCLC. The end points were overall survival (OS), progression-free survival (PFS), overall response rate (ORR), 1-year survival rate (1-year SR) and grade 3 or 4 toxicities. The pooled hazard ratio (HR) or risk ratio (RR), with their corresponding 95% confidence intervals (CI) were calculated employing fixed- or random-effects models depending on the heterogeneity of the included trials. Results: Eight randomized controlled trials (totally 3218 patients) were eligible. Our meta-analysis results showed that EGFR-TKIs were comparable to standard second-line chemotherapy for advanced NSCLC in terms of overall survival (HR 1.00, 95%CI 0.92-1.10; p=0.943), progression-free survival (HR 0.90, 95%CI 0.75-1.08, P=0.258) and 1-year-survival rate (RR 0.97, 95%CI 0.87-1.08, P=0.619), and the overall response rate was higher in patients who receiving EGFR-TKIs(RR 1.50, 95%CI 1.22-1.83, P=0.000). Sub-group analysis demonstrated that EGFR-TKI monotherapy significantly improved PFS (HR 0.73, 95%CI: 0.55-0.97, p=0.03) and ORR (RR 1.96, 95%CI: 1.46-2.63, p=0.000) in East Asian patients, but it did not translate into increase in OS and 1-year SR. Furthermore, there were fewer incidences of grade 3 or 4 neutropenia, febrile neutropenia and neutrotoxicity in EGFR-TKI monotherapy group, excluding grade 3 or 4 rash. Conclusion: Both interventions had comparable efficacy as second-line treatments for patients with advanced NSCLC, and EGFR-TKI monotherapy was associated with less toxicity and better tolerability. Moreover, our data also demonstrated that EGFR-TKImonotherapy tended to be more effective in East Asian patients in terms of PFS and ORR compared with standard second-line chemotherapy. These results should help inform decisions about patient management and design of future trials.

A Study on the Essential Information to Collect Disaster Sites for Effective Disaster Management : Focused on Jecheon Sports Center Fire case (효율적인 재난 상황관리를 위한 재난현장 필수정보 연구: 제천 스포츠 센터 화재사건을 중심으로)

  • Cho, Jung-Yun;Song, Ju-Il;Jang, Moon-Yup;Jang, Cho-Rok
    • Journal of the Society of Disaster Information
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    • v.16 no.1
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    • pp.70-78
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    • 2020
  • Purpose: When a disaster occurs, information is collected and sent indiscriminately to the disaster safety situation room, making it difficult to make quick and correct decisions. Therefore, in this study, both the field response team and the situation room attempted to derive the essential information elements for disaster management so that they can identify and respond optimally. Method: In this study, the actual disaster response process was first identified based on the case of large-scale fire disasters in multi-dense facilities. Afterwards, essential information on disaster management was obtained by analyzing the standard manual for large-scale fire crisis management in multi-dense facilities and the fire situation report form prepared at the time of disaster. Result: The Essential information on disaster management was divided into four stages: situation reception·reporting·transmission, total response·regional emergency rescue control group·regional disaster safety task force, operation stage of central emergency rescue control group·central disaster safety task force, and recovery stage. Since then, the information to be collected at each stage and the information relevant to core tasks are presented. Conclusion: The Essential information on disaster management thus obtained can serve as a guide for the person who collects information on site to collect information efficiently. In addition, it is expected that the situation room in charge of disaster response decision-making will receive only the information necessary for decision making, so that it is possible to make a quick situation decision and more efficient disaster situation management.

The Effects and the Development of Backward Course Design in the 'Biology and Environment' Classes of the Elementary School (초등학교 과학 '생물과 환경' 단원에서 백워드 디자인의 적용 효과)

  • Ham, Junghwa;Sim, Jaeho
    • Journal of Science Education
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    • v.41 no.1
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    • pp.80-97
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    • 2017
  • The purpose of this study was to develop understanding-oriented materials based on backward course design model and analyze their effects on 'biology and environment' unit of elementary school science. Backward Design starts from a specification of learning outcomes and decisions on methodology and syllabus are developed from the learning outcomes. This method has a strength maintaining consistency between educational contents-evaluation-learning activities and also promoting student's authentic understanding. The 78 students 6th graders participated in this experiments. Data was collected using project activities, the science academic emotion scale and academic achievement. The collected data was analyzed by t-test and ANCOVA analysis using the SPSS 23 statistical program. The following major conclusions were drawn on the basis of data analysis. First, the experimental group showed a relatively accurate understanding of the contents of science but they could not produce creative output in two project activities. Second, the interaction effect of the instruction based on backward curriculum design and science academic emotion was not significant statistically. Third, the experimental group showed a significant improvement in the academic achievement of 'biology and environment' unit.

Paramedic students' perceptions of Abortion, and Suicide (응급구조학과 학생들의 낙태와 자살에 대한 인식)

  • Baek, Mi-lye;Woo, Sung-hee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.05a
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    • pp.708-711
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    • 2017
  • The purpose of this study was to examine the perception of abortion and suicide for 115 paramedic students in 2016. The questionnaire consisted of perception of abortion(8items), the perception of suicide(58items), related 6items of the abortion and related 2 items of the suicide. The collected data were analyzed through t-test, Chi-squared test and ANOVA, using SPSS 21.0. As a result, the total perception score against abortion was $20.57{\pm}4.12$ and the total score of suicide perception was $-14.16{\pm}15.76$. The most answer was that pregnant women were abortion decision makers in both male and female students, and abortions were the highest when they might be unwanted pregnancies. The group who had thought about suicide was higher of perceptions of suicide than the group who did not. The female students who had suicide attempt or suicide experience of close acquaintances showed higher suicide perception score than those who did not. Therefore, A bio-ethics education curriculum should be prepared to establish ethics that respects life for future paramedic students who must make decisions at the boundary between death and life. It is necessary to raise the level of positive suicide perceptions through continuing counseling and education focusing on students who have experienced suicide by family members or acquaintances.

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An Empirical Assessment of Competency Requirements for Logistics Managers of Freight Forwarding Companies (복합운송주선업 물류관리자의 자격요건에 관한 연구)

  • Kim, Jin-Su;Hong, Eui
    • International Commerce and Information Review
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    • v.14 no.2
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    • pp.147-172
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    • 2012
  • The aim of this research is to identify the competencies required by freight forwarding company logistics managers or supply chain managers. And this research also attempts to show their relative importance and key knowledge areas that require improvement. Using a survey questionnaire, data was collected against forty three logistics and supply chain management skills or competencies, which were then grouped into four categories and analysed. The Analysis revealed that supply chain awareness, ability to make decisions, analytical skill, communication skill, supply chain cost, people skill, and integration of internal or external information flow which belong to logistics planning group are considered the most important competencies for effective and efficient logistics functioning. On the other hand, reverse logistics and IATA regulations from environmental awareness group show little influence on logistics managers for improving their logistics performances. The results have implications for a variety of parties including prospective logisticians, students, teachers and companies considering expanding their business to Chinese market. For example, the results permit companies to employ appropriate logistics managers who are qualified with sufficient skills and competencies suggested in this research. In the case of practitioners, the results provide a benchmark for comparison with their current level of abilities and suggested competencies.

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An Empirical Assessment of Competency Requirements for Logistics Managers in China (중국진출 한국기업 물류관리자의 자격요건에 관한 연구)

  • Hong, Eui;Kim, Jin-Su
    • International Commerce and Information Review
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    • v.13 no.4
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    • pp.251-274
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    • 2011
  • The aim of this research is to identify the competencies required by logistics managers or supply chain managers in China. And this research also attempts to show their relative importance and key knowledge areas that require improvement. Using a survey questionnaire, data was collected against forty three logistics and supply chain management skills or competencies, which were then grouped into four categories and analysed. The Analysis revealed that supply chain awareness, ability to make decisions, analytical skill, communication skill, supply chain cost, people skill, and integration of internal or external information flow which belong to logistics planning group are considered the most important Competencies for effective and efficient logistics functioning. On the other hand, reverse logistics and IATA regulations from environmental awareness group show little influence on logistics managers for improving their logistics performances. The results have implications for a variety of parties including prospective logisticians, students, teachers and companies considering expanding their business to Chinese market. For example, the results permit companies to employ appropriate logistics managers who are qualified with sufficient skills and competencies suggested in this research. In the case of practitioners, the results provide a benchmark for comparison with their current level of abilities and suggested competencies.

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Studies on Computerization of the Korean Libraries (한국 도서관의 컴퓨터 기술 도입에 관한 연구)

  • Chun Myung Sook
    • Journal of the Korean Society for Library and Information Science
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    • v.17
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    • pp.161-201
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    • 1989
  • 1. Introduction Korean society is moving toward an information society in 2000. At present a few Korean libraries are computerized and networks between libraries have yet to be formed. And there is no study done on the computerization of the Korean libraries. Therefore, this study will attempt to find elements that influence the computerization of Korean libraries. This research is composed of the following three parts. 1) Survey on the present status of computerized Korean libraries. 2) The influencing factors for Korean library computerization on the level of organization. 3) The relationship between professionalism and the access to the computer information on the level of librarians. 2. Hypothesis The basic hypothesis of this research is from the theory of the innovation of organization by Moch. He found that the size of the organization, specialization of the staffs, the task differentiation, and decentralization of decision making were the underlying influence for the organizational innovation. From this theory, hypothesis were formulated as follows. 1) The size of the library influences the library computerization. 2) Specialization of the librarians influences the library computerization. 3) Differentiation of the library services influences the library computerization. 4) The decision making process influences the library computerization. 3. Collection of the data Questionnaires were sent to 21 computerized libraries among which were 8 experimental group and 7 other controlled group libraries. Data were collected from April to July 1988. 4. Findings 1) The present status of Korean library computerization. -Korean libraries are computerized mostly in cataloguing. -The computer technology gate-keepers are mainly librarians. -The computerization budgets are not specifically allocated or funded by the organization but librarians made decisions to allocate library budget for the computer application. Gradually, more libraries are being funded specially for library computerization. 2) Factors that influence library computerization. -The size of the western books and the number of western periodical subscription influence the library computerization. -The number of annual book increase influences library computerization. -The number of annual book use influences library computerization. -The number of annual library users does not influences library computerization. - The size of the library budget influences the library computerization. -Librarian's specialization influences the library computerization. -Differentiation of library service influences the library computerization. Information service is positively related to the library computerization while data service is not related to the library computerization. -Decentralization of decision making in library service influences the library computerization.

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Psychosocial Experience in Cheonan Warship Incident Survivors ('천안함 사건' 유가족의 심리사회적 경험)

  • Lee, Yoon-Soo
    • Korean Journal of Family Social Work
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    • no.43
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    • pp.87-110
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    • 2014
  • This study is to understand the psychosocial experience in 'Cheonan Warship Incident Survivors'. The study question was how psychosocial experience in The Union of Family Bereaved by Cheonan Warship had been progressed. To answer this question 4 representers ofthe group and 2 reporters had been interviewed using a qualitative research method based on Phenomenology method. From this study the group's experience in had been revealed that they first crisis intervention are to identify and reinforce the strengths and coping skills of a one's family. Second, they gathered their opinion together and assigned the roles to the members, and then, requested what they want responding reasonably. The families' love, the representers' quick judgements and decisions, and the embarrassment of the military and media for the dead, who had been abandoned for long and decayed under the cold ocean, made the national support and respectful treatment possible for the dead and the family. The results of study will be applicable for individuals and groups, who need social work service as an empowerment intervention approach and crisis intervention are to identify and reinforce the strengths and coping skills of a one's family. The social worker's ability to anticipate, understand, and give therapeutic direction to the crisis reaction and the concerns of family members helps to bring around a successful crisis resolution. It is clear to us that wars, suicides, homicides in school settings, disaster and other events are providing unique challenges to social workers who are interested in learning more about the effects such events have on victims of traumatic events.

The Practice of Vocational and Meister High Schools' Admission Selection and Students' School Choices Through Admission Process (특성화고 및 마이스터고 입학전형 실태: 학교의 학생 선발과 학생의 진학 결정)

  • Paik, Sunhee;Lee, Jee Young
    • Journal of vocational education research
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    • v.36 no.1
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    • pp.1-22
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    • 2017
  • This study examined the process of admission selection of vocational high schools and meister high schools and how the process have been utilized by schools to select appropriate students and by students to make decisions for application in consideration of their interests, aptitudes, and career paths. To address the purpose of this study, Focus Group Interviews(FGI) were conducted with three groups of participants: vocational high schools and meister high schools teachers, high school freshmen' parents, and middle school teachers who had many students advanced to vocational and meister high schools. The findings indicated that during the promotion process, schools made efforts to attract students with higher GAP and provided information mainly regarding employment rate instead of curriculum or program of majors. Since schools usually visited middle schools where higher GPA students were, not all students had balanced opportunities of high school promotions and enough information about majors. For the application process, the schools placed a high value on scholastic performance while students applied high schools considering their interests, aptitudes, and career paths. In terms of admission type and criteria, the high school teachers reported no big differences between special admission and general admission while students took advantage from the special admission process which was less competitive than general admission. Based on the findings, a number of suggestions were made in order to improve the process of admission selection of vocational high schools and meister high schools.

The Effects of STEAM Program on Preservice Science Teachers' Communication Competency: Their Experiences and Reflection on STEAM Education (STEAM 프로그램이 예비 과학교사의 의사소통역량에 미치는 영향: STEAM 교육에 대한 경험과 성찰)

  • Kim, Sun Young;Jeon, Jae Hyeong
    • Journal of Science Education
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    • v.43 no.1
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    • pp.136-156
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    • 2019
  • This study examined the effects of STEAM program on preservice science teachers' communication competency and further explored their experiences of and reflection on STEAM program. The study design is one group pretest-posttest with mixed methodology using both quantitative and qualitative data. The STEAM program consists of three stages: introduction of STEAM, participation in STEAM activities, and reflection on the STEAM program. The preservice science teachers improved their communication competency after the STEAM program (p < .01). The preservice science teachers represented statistically higher scores on the three subscales of communication competency: Interpretation ability, self-presenting ability, and understanding others' viewpoints. In addition, the preservice science teachers reflected on their STEAM experiences. During the first stage of 'Presentation of the Problem Situation,' the preservice science teachers mentioned that they roused their curiosity due to everyday experience-related, social issues or present issues. In the stage of 'Creative Design,' the preservice science teachers mentioned that they selected the final idea through mutual consent of the members, the practical possibility of everyday life, the previous experience-based decisions, or persuasive power. Further, about 87.5% of preservice science teachers mentioned that they were fully engaged in the 'Emotional Learning' stages due to the application of integrated thinking, everyday related issues, and communication among group members. About 85% of the preservice science teachers mentioned that they could challenge new problems in future situations.