• 한국병원경영학회지
• /
• 제9권3호
• /
• pp.1-17
• /
• 2004

This study is aimed to assess the general population's attitude toward the continuity of medical care and its related factors. Self administered questionnaire was performed on the 1,120 office workers in the C city, Gang-won province. The questionnaire included the attitude of the continuity of medical institute, the intention of medical service use on a given case, and the variables of the related factors. 58.8% of the total respondents agreed to sustaining treatment without changing medical institutes; on the other hand, 41.2% showed negative attitude. In case that a patient would gain a recommendation of a surgery, hospitalization, or a specific examination, the total respondents' 84.9%, 61.8%, and 50.8% of each recommended situation said that they would visit another doctor and gain a diagnosis. As a result of multiple logistic analysis of determinant factor on continuity, reliability of doctors was statistically significant factor. In order to reduce wastefully used medical resources and offer well-qualified medical service, a system of second opinion among peer group or beforehand agreement could be possibly adopted. In addition, improving the image and reliability of a doctor could be an important factor to make better the behavior of medical service shopping; therefore, an effort to improve the relationship between a doctor and a patient, and restore the reliability of doctors should be paralleled.

• 동의생리병리학회지
• /
• 제23권5호
• /
• pp.1145-1153
• /
• 2009

The object of this study was to obtain acute information single oral dose toxicity of Mahwangbujaseshin-tang extracts, with mouse bone marrow cell micronucleus test for detecting possible genotoxicity. In order to observe the 50% lethal dose, approximate lethal dosage, maximum tolerance dosage and target organs, test articles were once orally administered to ICR mice at dose levels of 2000, 1000, 50 mg/kg according to the recommendation of KFDA Guidelines. The mortality and changes on body weight, clinical signs and gross observation were monitored during 14 days after dosing according to KFDA Guidelines with organ weights of 12 types of principle organs. In addition, after twice oral treatment of Mahwangbujaseshin-tang extracts 2000, 1000 and 500 mg/kg, we checked the changes on the number of MNPCE. We could not find any mortality, clinical signs, changes in the body weight and gross findings upto 2000 mg/kg treated group. The limited dosages in rodents except for increases of lymphoid organ weights and hypertrophy encounted as results from pharmacological effects of Mahwangbujaseshin-tang extracts, immune modulator effects with some sporadic accidental findings not toxicological signs. No evidence of increases of MNPCE numbers were also detected in all three different dosages of Mahwangbujaseshin-tang extracts treated mice. The results obtained in this study suggest that the LD50 and ALD of Mahwangbujaseshin-tang extracts in mice were considered as over 2000 mg/kg because no mortalities were detected upto 2000 mg/kg that was the highest dose recommended by KFDA and OECD. And the results of mouse bone marrow micronucleus test of Mahwangbujaseshin-tang extracts is negative results.

• 동의생리병리학회지
• /
• 제28권2호
• /
• pp.186-194
• /
• 2014

The object of this study was to obtain acute toxicity information (single-dose oral toxicity) of Woohwangchungshim-won (WHCSW), a pill type herbal medicine used in Korean Medicine (KM) for treating stroke. In order to obtain the 50% lethal dose (LD50), approximate lethal dosage (ALD) and target organs, WHCSW powders were once orally administered to female and male ICR mice at dose levels of 2,000, 1,000, 500 and 0 (control) mg/kg (body weight.) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines (Notification No. 2009-116). The mortality and changes in the body weight, clinical signs and gross observation were monitored for 14 days after single-dose oral administration of WHCSW according to KFDA Guidelines with organ weights and histopathological changes were observed in 12 principle organs. After single-dose oral administration of WHCSW, we could not find any mortality and toxicological evidences up to 2,000 mg/kg-administered group, except for some accidental findings and dose-independent increases of body weight gains in female 1,000 and 500 mg/kg-administered female mice. The results obtained in this study suggest that the LD50 and ALD of WHCSW in both female and male mice after single-dose oral administration were considered as over 2,000 mg/kg because no mortalities were detected up to 2,000 mg/kg that was the highest dose recommended by KFDA and Organization for Economic Co-Operation and Development (OECD), and can be safely used in clinics.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권4호
• /
• pp.1687-1692
• /
• 2012

Background: Few studies have examined theoretically informed constructs related to hepatitis B (HBV) testing, and comparisons across studies are challenging due to lack of uniformity in constructs assessed. The present analysis examined relationships among Health Behavior Framework factors across four Asian American groups to advance the development of theory-based interventions for HBV testing in at-risk populations. Methods: Data were collected from 2007-2010 as part of baseline surveys during four intervention trials promoting HBV testing among Vietnamese-, Hmong-, Korean- and Cambodian-Americans (n = 1,735). Health Behavior Framework constructs assessed included: awareness of HBV, knowledge of transmission routes, perceived susceptibility, perceived severity, doctor recommendation, stigma of HBV infection, and perceived efficacy of testing. Within each group we assessed associations between our intermediate outcome of knowledge of HBV transmission and other constructs, to assess the concurrent validity of our model and instruments. Results: While the absolute levels for Health Behavior Framework factors varied across groups, relationships between knowledge and other factors were generally consistent. This suggests similarities rather than differences with respect to posited drivers of HBV-related behavior. Discussion: Our findings indicate that Health Behavior Framework constructs are applicable to diverse ethnic groups and provide preliminary evidence for the construct validity of the Health Behavior Framework.

• 한국인터넷방송통신학회논문지
• /
• 제14권3호
• /
• pp.75-80
• /
• 2014

교통문화를 구성하는 요소로 크게 법규 및 단속, 교통시설, 교육으로 볼 수 있다. 운전자는 운전 중 교통법규를 지켜야 하고 교통단속은 물리적인 처벌을 통해 운전자의 행동에 직접적인 영향을 미치고 교통문화의 형성에도 큰 영향을 미친다. 교통시설에 적응하는 운전행동이 누적되어 습관이 되고 이러한 습관이 모여 교통문화를 형성하게 된다. TCI 조사는 지자체별 교통문화 수준을 객관적으로 측정하여 교통행정기관과 학계 등에 교통문화 수준 향상을 위한 정책 개발 및 연구의 객관적인 기초자료를 제공하고자 시작되었다. 그러나 지역 간 상대적 비교를 통해 객관적인 비교와 선행적 추이의 유도, 각 지자체가 갖고 있는 평가 타당성에 관한 인식 등을 감안하면 조사결과의 품질을 보다 높여야 할 필요성 또한 증가하고 있어 개선이 필요한 실정이다. 이러한 문제에 관한 개선을 위해 교통문화와 관련성이 높은 사고건수 항목을 제시하였다.

• 디지털융복합연구
• /
• 제12권2호
• /
• pp.211-221
• /
• 2014

이 연구는 중국 보험소비자의 보험업에 대한 신뢰 결정요인을 구조방정식 모형을 통해 살펴보고, 생명보험과 자동차보험 간 보험소비자 신뢰 결정요인에 차이가 있는지를 잠재평균과 다집단분석을 통해 검증하였다. 분석결과, 중국 보험소비자의 보험업 신뢰 결정요인으로 가장 큰 영향을 미치는 것은 보험회사의 정직성이었고, 정직성 요인 다음으로는 보험회사가 장래 보험금 지급을 제대로 할 수 있는지를 포괄하는 공신력이 신뢰 결정요인으로 작용하고 있는 것으로 나타났다. 반면, 배려는 신뢰 결정요인으로서는 통계적으로 유의미하지 않았다. 한편, 보험소비자의 신뢰는 중국 보험시장에서도 추후 재가입이나 주변 사람 추천 등 관계몰입으로 강하게 연결됨을 보였다. 이러한 결과는 앞으로 보험업이 더욱 견고하게 지속 성장하기 위해서는 무엇보다 보험소비자의 신뢰 구축이 긴요하다는 것을 시사해 준다.

• 한국치위생학회지
• /
• 제15권5호
• /
• pp.759-765
• /
• 2015

Objectives: The purpose of the study was to investigate the choice motivation of dental clinics by patients. Methods: A self-reported questionnaire was completed by 577 patients visiting the dental clinics from October 6 to 25, 2014 in G city after explaining the purpose of the study and receiving the informed consent. The questionnaire consisted of sociodemographic characteristics and choice motivation of dental clinics using Likert 5 point scale. Results: 1. The traffic convenience was the highest in those who were the 30s (3.37) and unmarried person (3.30). Those having moderate oral health condition showed 3.23. The regular checkup group had 3.33. The physical environment was the highest in the 20s (3.37) and the unmarried persons (3.33). Those having master's degree showed 3.86. The reputation of the dental clinic image was the highest in those having master's degree (3.63). Those having moderate oral health condition had 3.28. The main reason for dental clinic visit was tooth extraction (3.79, p<0.05). 2. The top priority choice for the dental clinic was the access to the dental clinic and the next reason was reputation for the dentist. The other choice factors included trust for the dentist, recommendation, and night treatment. Conclusions: The important choice for the dental clinic included the access to the dental clinic and reputation for the dentist.

• 대한한방내과학회지
• /
• 제34권1호
• /
• pp.46-58
• /
• 2013

Objectives : The object of this study was to obtain acute information (single oral dose toxicity) of Scutellariae Radix Aqueous Extracts (SR; yield = 27.20%) which traditionally have been used in Korean medicine for treating various diseases including inflammatory diseases. Methods : In order to observe the 50% lethal dose ($LD_{50}$), approximate lethal dosage (ALD) and target organs, SR Aqueous Extracts were once orally administered to female and male ICR mice at dose levels of 2,000, 1,000, 500 and 0 (control) mg/kg (body weight.) according to the recommendation of KFDA Guidelines. The mortality and changes on body weight, clinical signs and gross observation were monitored during 14 days after single oral treatment of SR according to KFDA Guidelines with organ weights and histopathological observations of 14 types of principle organs. Results : After single oral treatment of SR, we could not find any mortality and toxicological evidences up to 2,000 mg/kg treated group, the limited dosages in rodents, on the body and organ weights, clinical signs, gross and histopathological observations, except for some accidental findings. Conclusions : The results obtained in this study suggest that the $LD_{50}$ and ALD of SR in both female and male mice after single oral treatment be considered as over 2,000 mg/kg because no mortalities were detected up to 2,000 mg/kg that was the highest dose recommended by KFDA and OECD, and can be safely used in clinics.

• 한국지반환경공학회 논문집
• /
• 제10권7호
• /
• pp.67-79
• /
• 2009

댐의 경과년수에 따라 고장으로 폐기되는 매설계기의 지속적인 증가로 인해 기존 필댐의 유지관리를 위한 계측시스템의 재정립이 필요한 상황이지만 필댐의 파괴모드와 계측기의 중요도에 대한 체계적이고 정량적인 분석 없이 과거의 경험과 소수 전문가의 자문의견에만 의존하여 유지관리 계측계획을 수립하고 있는 실정이다. 본 연구에서는 선행연구(Andersen 등, 1999)를 기초로 하여 5개 기존 필댐 계측항목의 중요도를 정량적으로 분석하여 우선순위를 산정한 결과로서 상세 외관조사와 함께 침투수량계, 표면 침하점, 간극수압계에 대한 상시 모니터링 체계의 구축을 기존 필댐 계측시스템의 재정립 방안으로 제시하였으며 이것은 일본토목연구소(1984), 일본 대댐회(국토교통성, 1986)의 권고사항과 Bagherzadeh-Khakkahali와 Mirghasemi(2005)의 분석결과와도 잘 일치하는 것으로 나타났다.

• 대한불안의학회지
• /
• 제2권2호
• /
• pp.108-114
• /
• 2006

Objectives : Only a few prospective studies of panic disorder are available. This study investigated naturalistic outcome of panic disorder patients at twelve months after the initial diagnosis. Methods : A total of 84 subjects were diagnosed with panic disorder by diagnostic interview, Structured Clinical Interview for DSM-IV (SCID-IV) and Anxiety Disorder Interview Schedule for DSM-IV (ADISIV). Among them, 80 subjects could be evaluated by means of Panic Disorder Severity Scale (PDSS) at follow-up interview after twelve months. Treatment continuation was also examined at follow-up interview. Results : At initial intake, 80 patients were classified into 22% with mild, 33% with moderate-to-marked, and 45% with severe symptoms on the basis of their PDSS total score. At twelve months, 20% of patients reached remission, 65% had mild and 15% had moderate-to-marked symptoms. Initial panic symptom severity, presence of agoraphobia, panic symptom duration before diagnosis, number of comorbid Axis I disorders were associated with significantly higher PDSS total score at twelve months. Forty six percent of total patients continued medication and 23% have stopped treatment by clinician's recommendation and 31% have selfdiscontinued their medication. At twelve months, all three groups were improved but self-discontinuation group had significantly higher PDSS total score. Conclusion : In the one-year naturalistic outcome study of panic disorder patients, high percentage of patients achieved remission or had mild symptoms.