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The Effect of Korean Prospective Drug Utilization Review Program on the Prescription Rate of Drug-Drug Interactions (의약품 처방·조제지원서비스(Drug Utilization Review)사업이 병용금기 처방률에 미치는 영향)

  • Kim, Dong-Sook;Park, Juhee;Jeon, Ha-Rim;Park, Chanmi;Kang, Hyeun Ah
    • Health Policy and Management
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    • v.24 no.2
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    • pp.120-127
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    • 2014
  • Background: Since December 2010, online computerized prospective drug utilization review (pDUR) has been implemented in Korea. pDUR involves the review of each prescription before the medication is dispensed to the individual patient. The pDUR is performed electronically by Health Insurance Review & Assessment Service (HIRA), which is a Korean governmental agency, and then HIRA provides medical institutions and pharmacies with information that can be helpful to them in preventing potential drug problems such as drug/drug interactions or ingredient duplication. The aim of this study was to assess the impact of the Korean pDUR implementation on the proportion of drug-drug interactions (DDIs) using claims data from HIRA. Methods: A before-after comparison of the prevalence of DDIs between prescription was conducted, using HIRA administrative claims data of medical institution from January 2010 to December 2011. The analysis unit was the prescription issued and pairs before and after. The main outcome measures were the proportion of DDIs within- (control group) or between- physician encounters. To examine the difference, a paired t-test was applied. Results: We found that DDIs proportion between prescription decreased significantly (t=3.04, p=0.0026) after the implementation of pDUR, whereas there is no significant reduction within prescription (t=1.15, p=0.2518). With respect to the prevalence of DDIs between drug groups, the most dramatic reduction was occurred between 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and anti-fungal agents. Conclusion: It seems effective that giving a direct feedback to prescribers by a prospective DUR. Further research is needed to assess the impact of DUR to final outcomes such as hospitalization.

Development of a Smartphone Application for Promoting Bone Health in Korean Young Adult Women: A Pilot Study (성인초기 여성의 골건강 증진을 위한 스마트폰 앱 개발 및 적용: 예비연구)

  • Park, Young-Joo;Lee, Sook-Ja;Shin, Nah-Mee;Shin, Hyunjeong;Yoon, Sungjin;Jeon, Songi;Cho, Inhae
    • Korean Journal of Adult Nursing
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    • v.27 no.4
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    • pp.459-471
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    • 2015
  • Purpose: The purpose of this study was to develop a smartphone application and evaluate it's effectiveness and usability for promoting bone health in Korean young adult women. Methods: A smartphone application was developed covering exercise, nutrition, and health habits related to bone health. A pilot testing was conducted using a one-group pre/posttest design. A total of 22 female college students with low bone mass participated in the 8-week use of a pilot testing. Results: The "Strong bone Fit body (SbFb)" application was developed using Android platform. In the pilot testing, bone mineral density, serum CTX, and 25 (OH)Vit.D were significantly decreased. There is no significant change in serum osteocalcin and calcium. Serum phosphorus concentration, nutrient intakes (fiber, VitB6, and pantotenic acid), and all bone composition profiles were significantly increased. Bone-health knowledge was significantly increased but no change in health belief and self-efficacy. Conclusion: The results of this pilot testing suggest the effectiveness of the SbFb application to enhance and promote self-managing abilities for bone health. It can provide continuous feedback and high-quality bone health information. However, some contents and working methods of the application need to be modified and its effectiveness on bone health requires further investigations.

Design of a Linear CMOS OTA with Mobility Compensation and Common-Mode Control Schemes (이동도 보상 회로와 공통모드 전압 조절기법을 이용한 선형 CMOS OTA)

  • Kim, Doo-Hwan;Yang, Sung-Hyun;Kim, Ki-Sun;Cho, Kyoung-Rok
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.43 no.12 s.354
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    • pp.81-88
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    • 2006
  • This paper describes a new linear operational transconductance amplifier (OTA). To improve the linearity of the OTA, we employ a mobility compensation circuit that combines the transistor paths operating at the triode and subthreshold regions. The common-mode control schemes consist of a common-mode feedback (CMFB) and common-mode feedforward (CMFF). The circuit enhances linearity of the transconductance (Gm) under the wide input voltage swing range. The proposed OTA shows ${\pm}1%$ Gm variation and the total harmonic distortion (THD) of below -73dB under the input voltage swing range of ${\pm}1.1V$. The OTA is implemented using a $0.35{\mu}m$ n-well CMOS process under 3.3V supply.

A Study on the Relationship between Job Characteristics and Individual Learning Agility and Learning Satisfaction (군 직무특성 및 개인 학습민첩성과 학습만족도 간의 관계 연구)

  • Choi, Soonwon;Jeon, Ki Seok
    • The Journal of the Korea Contents Association
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    • v.20 no.6
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    • pp.197-210
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    • 2020
  • Learning agility is the will and ability to flexibly change thoughts and behaviors by quickly learning in new environments and experiences, and is a core competency to overcome crisis and solve organizational problems. It is a concept that can be used in the same organization group. Based on the previous research, a study was conducted to investigate how the job characteristics and personal learning agility of the army deputy officers influence learning satisfaction. After receiving a questionnaire survey of 216 business and yarn companies, SPSS 24.0 was used to verify the reliability and validity of the measurement variables, and the hypothesis was verified by regression analysis. It was found that some of the sub-categories of personal learning agility (self-awareness, active change pursuit) had a positive effect on learning satisfaction. This means that in order to enhance the effectiveness of military cyber education, measures should be taken to avoid overload in the field, and in order to increase performance in military organizations, personal learning agility pursuing positive change based on self-awareness and feedback must be developed.

An Analysis on Bibliotherapy Experiences of Bibliotherapists in Library (도서관 독서치료사의 독서치료 경험 분석)

  • Lim, Seong-Gwan
    • Journal of Korean Library and Information Science Society
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    • v.47 no.2
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    • pp.417-436
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    • 2016
  • The aim of this study is focused on knowing what bibliotherapists experience while they are in a session with their clients in library settings. Qualitative interviews were conducted as the main research tool or method used for this study. The study participants included 12 bibliotherapist respondents specializing in library. They were divided into two groups of 6 and each group was interviewed for approximately 2 to 3 hours. The interview employed a question asking methodology modified from that presented and/or originally used by Kruger and Casey(2000). The interview utilized open ended questions in the order of starting, introduction, main, and ending questions. Analyses of the interviews were based on methods presented by Morgan and Scannell(1998). Results of the study show that experiences through therapy sessions consisted of 7 different themes, 26 specific categories, and 84 unique concepts. The purpose of the study was to observe the problems bibliotherapist have or may encounter in library settings, provide feedback to make each session better, and as a result, help both the library and bibliotherapist during the bibliotherapy process.

A Simulation of Δ-Σ Modulators for Frequency Synthesizers of FMCW Radars (FMCW 레이더 주파수합성기용 델타-시그마 변조기의 시뮬레이션)

  • Hwang, In-Duk;Kim, Chang-Hwan
    • The Journal of the Korea institute of electronic communication sciences
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    • v.7 no.4
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    • pp.707-714
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    • 2012
  • After a single-stage, second-order, multiple-feedback ${\Delta}-{\Sigma}$ modulator and a two-stage, second-order MASH ${\Delta}-{\Sigma}$ modulator were analyzed and simulated using Simulink and Matlab and their characteristics were compared, the following result was obtained: 1) The two ${\Delta}-{\Sigma}$ modulators do not have group delay distortion. 2) The characteristics of the noise shaping are nearly identical. As a result of the noise shaping, the power spectral densities have slope of 40 dB/dec. 3) There was no spurious tone. 4) The input range of the two modulators is from -1 to +1 in common. 5) Because the output of the two-stage MASH modulator is 2-bits (4-levels), design of frequency dividers and charge pumps of PLL are more demanding.

Fun Factors of the Classes for the Gifted Based on Concept Mapping Approach (개념도 분석을 통해서 본 초등 영재수업에서의 '재미' 요인 탐색)

  • Yun, Jahwan;Han, Kisoon
    • Journal of Gifted/Talented Education
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    • v.26 no.2
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    • pp.389-404
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    • 2016
  • This research aims to build a concept map reflecting gifted elementary students' perception on fun factors of the classes for the gifted. Data for this research was gathered through brainstorming of 80 students currently attending classes for the gifted. 10 of them were selected as focus group for classification and evaluation, and 140 gifted-class students were asked of the fun factors for level of agreement after concept map analysis. Results of the research were, first, 46 final statements about fun factors which are categorized into 6 sub-categories ('the gifted class teacher's encouragement and feedback', 'confidence and chance', 'teamwork and intimacy with gifted friends', 'fulfilling, beneficial, and rewarding feeling', 'new and special experiments', 'qualitatively different class level and learning environment'). Second, the gifted students showed highest level of agreement on 'new and special experiments' category among the 6 sub-categories. Implication of this research on the field has been discussed.

STUDIES ON IMMUNOTOXIC POTENTIAL OF METHAMPHETAMINE (MA) IN Balb/C MICE I. Changes of Lymphoid Organs and Inhibitory Effect of Lymphocyte Proliferation to Mitogen

  • Lim, Chae-Woong;Rim, Byung-Moo;Lee, Ho-Il;Kim, Sang-Ho
    • Toxicological Research
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    • v.11 no.1
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    • pp.9-14
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    • 1995
  • The immune system is partially under the control of the sympathetic and parasymphathetic nervous systems through the regulatory feedback loop. Methamphetamine (MA) is a neurotoxic chemical which affects the neurotransmitter system. The objective of this study was to investigate the immunotoxic effect of MA on the major immune target organ and lymphocyte proliferation to the various mitogens. Female Balb/C mice, 15 to 20 g, were injected subcutaneously with 0, 0.5, or 5 mg MA/kg for 14 consecutive days. In MA treated mice, the body weight gain and relative spleen and thymus weight were decreased in doserelated manner. Histopathologically, there was a paucity of lymphold follicles and germinal centers in the spleen, and thymic cortical atrophy with lymphophagocytosis was prominent. Apoptosis also occurred in germinal centers of spleen and thymic cortex. The threshold and peak of lymphocyte proliferation at various concentration of mitogens showed similar patterns. However, the response to lipopolysaccaride (LPS) and pokeweed mitogen (PWM) in the 5 mg MA/kg treated group showed threshold and peak proliferation at high concentration of mitogens (25${\mu}g$ LPS/ml for MA vs 15${\mu}g$ LPS/ml for control; 60${\mu}g$ PWM/ml for MA vs 45${\mu}g$ PWM/ml for control), which suggest that MA impairs T cell dependent-B cell function. This preliminary study indicated that MA affected the lymphold organs and immune function.

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Study on Activity, Type and Establishment of Community Supported Agriculture in USA and Japan (미국과 일본의 CSA운동의 등장, 유형 및 활동사례)

  • 정진영;손상목;김영호
    • Korean Journal of Organic Agriculture
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    • v.9 no.1
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    • pp.1-16
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    • 2001
  • With increasing global concern that intensively synthetic-chemical based farming systems accelerated the decline in environmental quality, the sustainability of modem agriculture became the subject of great concern. It is well known that the movement of Community Supported Agriculture(CSA) has been contributed significantly to the development of organic agriculture in USA and Japan. It was supposed that CSA could be one of the best way to promote the movement of organic agriculture since there is little reliability on the organically grown food by consumer. In this paper it was focussed to study the movement of CSA in USA and Europe in order to provide an idea for establishment and movement of CSA in Korea to support the organic agriculture. In a CSA system, the farmer grows food for a group of shareholders who pledge to buy a portion of the farm's crop that season. This arrangement gives growers up-front cash to finance their operation and higher prices for produce, since the middleman has been eliminated. For most shareholder for CSA saving money is a secondary consideration, but fresh safe products and environmentally sound farming system. People become shareholder of CSA since they expect an organic farming which can ; \circled1protect the environment, minimize pollution, promote health, \circled2replenish and maintain long-term soil fertility by providing optimal conditions for soil biological activity, \circled3maintain diversity within the farming system and its surroundings and protect plant and wildlife habit, \circled4recycle materials and resources to the greatest extent possible within the farm and its surrounding community, \circled5maintain the integrity of organic food and processed products through each step of the process from planting to consumption, \circled6develop and adopt new technologies with consideration for their long range social and ecological impact. In all CSAs, the farmer develops a crop plan and a budget, which details costs for a growing season, including fair wages for the farmers. Experienced Information on increasing shareholder retention, the future of CSA, and getting started such as ideas for ongoing marketing, printed materials that set realistic expectations, working members, production, pick-up and delivery, setting prices, and receiving feedback were also briefly introduced.

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Residents' Usage of Community Facilities by Types of National Rental Apartment Complexes (단지특성에 따른 국민임대주택 커뮤니티시설의 거주자 이용 실태에 관한 연구)

  • Hwang, Yeon-Sook;Chang, Yun-Jung;Son, Yeo-Rym;Chang, A-Ri
    • Korean Institute of Interior Design Journal
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    • v.18 no.5
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    • pp.147-155
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    • 2009
  • The purpose of this study is to examine the residents' preference to community facilities in national rental apartment complexes. Twelve housing complexes were sampled and researched with questionnaire and field-surrey methods. The data from the questionnaire survey were processed with SPSS 14 and analyzed by regional group, size of complex, and arrangement plan of facilities. The complexes are located in two legions, Seoul and Gyounggi province. They were also sorted into three groups by size: less than 500 households, 500 to 1,000, and more than 1,000. Lastly, the complexes were categorized into three types: those where facilities are concentrated in or around a single building, dispersed into several places, and located in residential buildings. The results are as follows: Majority of the community facilities are established outdoor and, therefore, the indoor facilities are relatively more insufficient. Especially, there is a shortage of indoor gymnasium while the demand is increasing. It is partly because there is no regulatory guideline on indoor gym requirements in housing complexes. The resident satisfaction measurement shows significant comparison according to region and complex size. The level of satisfaction with garden/kitchen-garden, pond/fountain/streamlet is higher at the complexes in Gyunggi. The residents of larger complexes give positive feedback about spells facilities while those of smaller complexes are more satisfied with education-related facilities such as library and study. The measurement of resident needs shows significant comparison according to complex size and facility arrangement plan. The residents of smaller complexes are more in need of community facilities. In both regulatory standards and actual condition, community facilities are more insufficient at small complexes with less than 500 households.