• The Journal of Asian Finance, Economics and Business
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• v.7 no.2
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• pp.261-270
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• 2020

This study aims to examine the community empowerment model to develop sustainable tourism villages in Indonesia. This study applies a qualitative method. Data collection is conducted through interviews, observations, and focus group discussions held in Ponggok Village of Central Java Province - Indonesia. The results of this study found that the tourism development carried out in the Ponggok Village used four approaches (1) spatial approach as a basis in determining the direction of village development; (2) sectoral approach through increasing the role of the Village Owned Enterprises to build the village economy; (3) human resources to enhance the role of village communities in managing village potentials; and (4) use of information technology to improve service quality, transparency and accountability. The success of these four approaches is influenced by the leadership, innovation, collaboration, and good village governance. The success of the Ponggok village to become an independent village in improving the welfare of the community is inseparable from the success of the Ponggok village government in empowering the community to manage sustainable tourism development. The success of development with these four approaches is influenced by leadership, innovation, collaboration, and good governance.

• Nuclear Engineering and Technology
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• v.42 no.1
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• pp.1-8
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• 2010

Geological disposal is designed to provide safe containment of radioactive waste for very long times, with the containment provided by a combination of engineered and geological barriers. In the extreme long term, after many thousands of years or longer, residual amounts of long-lived radionulides such as Cl-36, but also radionuclides in the natural decay chains, may be released into the environment normally accessed and used by humans, termed here, the biosphere. It is necessary to ensure that any such releases meet radiation protection objectives through the development of a safety case, which will include assessment of radiation doses to humans. The design of such dose calculations over such long timeframes is not straightforward, because of the range of potentially relevant assumptions which could be made, concerning environmental change and changes in human behavior. These conceptual uncertainties are additional to those that more typically arise, for example, in the assessment of present day situations, but which also have to be addressed. The issue has therefore been subject to international cooperation for many years. This paper summarizes the evolution and results of that collaboration leading up to the present day, taking account of developments in international recommendations on radiation protection objectives and the more recent greater focus on preparation of site specific safety cases.

• The Journal of Industrial Distribution & Business
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• v.10 no.4
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• pp.13-24
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• 2019

Purpose - This research explores the impacts of third-party logistics (3PLs) within the aircraft Maintenance, Repair and Overhaul (MRO) industry in the United Arab Emirates (UAE) to explore the role of collaborative relationships for improving outsourcing. Globalization and time based competition have changed business environments and challenged the conventional management strategies that are related to core competencies and operational models. Organizations are forced to devise innovative practices in which logistics outsourcing to 3PLs offers significant advantages. Research design, data, and methodology - This case study was conducted within a leading global aircraft MRO organization whose reach spans across Europe, the Middle East, Asia and the Americas. The methods used face to face semi-structured interviews, validated through further focus group discussions. Results - These findings highlight the effectiveness of collaborative relationships on their role to improve outsourcing and also demonstrated that MROs gain several advantages from 3PL arrangements. However, any gaps in outsourcing management elevates potential risks to organizations as well, which could result in reputational, operational and financial losses. Conclusions - Although generalizability is not possible due to the case study approach, generality suggests that in order to reduce reputational, operational and financial risks, enhanced collaboration with 3PLs is recommended to optimize outsourcing arrangements.

• Asian Journal for Public Opinion Research
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• v.11 no.3
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• pp.201-233
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• 2023

Persons with disabilities (PwD) are believed to be a group that had a greater risk during the pandemic. While PwD are vulnerable to the spread of COVID-19 due to their high dependence on physical contact, a series of policies restricting public movement during the pandemic had the potential to place PwD in increasingly marginalized situations. This situation reinforces the urgency of crisis communication as one of the critical parts of the COVID-19 response to ensure that all levels and groups of society can accept and understand the flow of information. Using a qualitative approach, this research was conducted through in-depth interviews with PwD age 17-50 in the city of Makassar, Indonesia. The results of this study suggest that crisis communication during the pandemic should involve participatory communication, which focuses on collaboration with empowerment. The PwD communities need to be actively engaged during the communication process of a pandemic crisis to ensure that inclusiveness is always taken into account. During the distribution of information, the relevant health officers or the government at the regional level need to carry out more frequent socialization and special services for PwD based on the characteristics of their disabilities.

• BMB Reports
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• v.49 no.5
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• pp.245-246
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• 2016

The level and activity of critical regulatory proteins in cells are tightly controlled by several tiers of post-translational modifications. HIF-1α is maintained at low levels under normoxia conditions by the collaboration between PHD proteins and the VHL-containing E3 ubiquitin ligase complex. We recently identified a new physiologically relevant mechanism that regulates HIF-1α stability in the nucleus in response to cellular oxygen levels. This mechanism is based on the collaboration between the SET7/9 methyltransferase and the LSD1 demethylase. SET7/9 adds a methyl group to HIF-1α, which triggers degradation of the protein by the ubiquitin-proteasome system, whereas LSD1 removes the methyl group, leading to stabilization of HIF-1α under hypoxia conditions. In cells from knock-in mice with a mutation preventing HIF-1α methylation (Hif1α^KA/KA), HIF-1α levels were increased in both normoxic and hypoxic conditions. Hif1α^KA/KA knock-in mice displayed increased hematological parameters, such as red blood cell count and hemoglobin concentration. They also displayed pathological phenotypes; retinal and tumor-associated angiogenesis as well as tumor growth were increased in Hif1α^KA/KA knock-in mice. Certain human cancer cells exhibit mutations that cause defects in HIF-1α methylation. In summary, this newly identified methylation-based regulation of HIF-1α stability constitutes another layer of regulation that is independent of previously identified mechanisms.

• Journal of Korea Trade
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• v.24 no.1
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• pp.171-207
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• 2020

Purpose - This paper investigates the potential effect of the Regional Comprehensive Economic Partnership (RCEP) on trade liberalization among member countries in order to answer key questions in our research on whether the RCEP will be a cornerstone or just collaboration. Furthermore, it aims to measure the likely magnitude of the economic impact it has on its members. Design/methodology - Toward achieving research objectives, we developed a regional CGE model based on the GTAP 9 database. Findings - The simulation results show Korea, Australia, India, and Japan ranked the top countries with an average growth in GDP of 0.38 %, 0.36%, 0.29%, and 0.23%, respectively. Moreover, China and New Zealand followed with a percentage of 0.12% each. The lower economic performing group is the ASEAN group due to a contraction in GDP by 0.13%. Accordingly, there was a positive impact of the RCEP agreement on all member states, as empirically demonstrated. Furthermore, Korea is one of the countries that will benefit most from joining this agreement. Finally, this agreement is important; it has many economic benefits to member states, but it is not a cornerstone. Originality/value - The examination of the quantitative effects of tariff removal among the RCEP's countries is its value. We will address all member countries of the convention simultaneously using a regional CGE model GAMS language, where we employed a Mathematical Programming System for General Equilibrium (MPSGE) to establish a Regional CGE model. This study is directed to policymakers looking at evaluating RCEP agreement.

• Education of Primary School Mathematics
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• v.26 no.4
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• pp.317-332
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• 2023

Mathematical modeling activities hold the potential for diverse applications, involving the transformation of real-life situations into mathematical models to facilitate problem-solving. In order to assess the cognitive, affective, and social dimensions of students' engagement in mathematical modeling activities, this study conducted sessions with ten groups of fifth-grade elementary school students. The ensuing processes and outcomes were thoroughly analyzed. As a result, each group effectively applied mathematical concepts and principles in creating mathematical models and gathering essential information to address real-world tasks. This led to notable shifts in interest, enhanced mathematical proficiency, and altered attitudes towards mathematics, all while promoting increased collaboration and communication among group members. Based on these analytical findings, the study offers valuable pedagogical insights and practical guidance for effectively implementing mathematical modeling activities.

• Journal of Information Technology Applications and Management
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• v.22 no.2
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• pp.113-122
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• 2015

Collective intelligence can be an influential factor of decision-making based on collaboration and information exchange between individuals. Our study explores whether collective intelligence can mitigate the loss aversion effect, bias and error in human judgment, and collective intelligence in online communities can reduce the loss aversion effect. Our community settings display both individual-level and group-level loss aversion effect, investigate effective collective intelligence characteristics like investment commitment, participant experience. Using a multi-method approach our research comprises a web-based experiment with 100 participants investing 3 situations from a real-world community, data from a survey measuring loss aversion behavior of participants. The results suggest the loss aversion effect mitigates under the online-circumstance. Overall, our results suggest that, while collective intelligence mitigates the loss aversion effect, participants do not transfer these results to other settings.

• Journal of Dairy Science and Biotechnology
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• v.24 no.2
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• pp.21-24
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• 2006

The ubiquitous presence of lactoferrin(LF) receptor in human as reported by the research group of Prof. Bo Lonnerdal, Univ. California (Suzuki, Y. A.,2001) encouraged us to search for the unknown physiological roles of Lf. Under the collaboration with Prof. Etsumori Harada, Tottori Univ., and his research group, we have found two novel biological activities of LF as the control of the lipid metabolism and the effect on the central nervous system. Relating to the lipid metabolism, LF could, in animal experiments, reduce triglyceride and total cholesterol both in blood and liver (Takeuchi, T et αl., 2003). LF increased plasms HDL-C and lowered LDL-C. In the central nervous system, LF showed anti-nociceptive activity mediated by ${\mu}$-opioid receptor in the rat spinal cord (Hayashida, K. et al., 2003). LF enhanced analgesic action of morphine synergistically via nitric oxide synthesis (Hayashida, K., et al., 2003) LF showed opioid-mediated suppressive effect on distress induced by maternal separation in rat pups (Takeuchi, T., et al., 2003).

• 한국유가공학회:학술대회논문집
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• 2005.10a
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• pp.1-9
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• 2005

The ubiquitous presence of lactoferrin (LF) receptor in human as reported by the research group of Prof, Bo Lonnerdal, Univ. California, encouraged us to search for the unknown physiological roles of LF. Under the collaboration with Prof. Etsumori Harada, Tottori Univ., and his research group, we have found two novel biological activities of LF as the control of the lipid metabolism and the effect on the central nervous system. Relating to the lipid metabolism, LF could, in animal experiments, reduce triglyceride and total cholesterol both in blood and liver. LF increased plasma HDL-C and lowered LDL-C. In the central nervous system, LF showed anti-nociceptive activity mediated by ${\mu}$-opioid receptor in the rat spinal cord. LF enhanced analgesic action of morphine synergistically via nitric oxide synthesis. LF showed opioid-mediated suppressive effect on distress induced by maternal separation in rat pups.