• YAKHAK HOEJI
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• v.55 no.1
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• pp.11-15
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• 2011

Zabofloxacin is a novel broad spectrum fluoroquinolone with excellent anti-pneumococcal activity. We investigated the in vitro activity of zabofloxacin against clinical isolates of gram-positive bacteria and the in vivo activity against systemic infection in mice. Zabofloxacin was very active against gram-positive bacteria except QRSA (Quinolone-resistant S. aureus) and VRE(Vancomycin-resistant Enterococci). Especially, zabofloxacin was extremely potent against clinical isolates of Streptococci. Zabofloxacin was as active as gemifloxacin against systemic infection in mice. In view of its improved antibacterial activities against gram-positive bacteria and good pharmacokinetic profiles in animals, the clinical usefulness of zabofloxacin should be established by further studies.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.39.2-39
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• 1981

Recently, there has been many problems in the treatment of OMPC, because of inadequate and abuse of antibiotics, and resistant strain of pathogenic organisms to antibiotics. Authors studied on the culture and sensitivity of otorrhea obtained from 50 patients with OMPC, and evaluated the therapeutic effect of PPA, which is a new derivative of piromidic acid and active against gram (-) bacteria including pseudomonas aeruginosa as well as some gram (+) bacteria. We observed good therapeutic effect on OMPC with pseudomonas and other gram (-) bacteria, and considerable effect on OMPC with gram (+) bacteria.

• KIPS Transactions on Computer and Communication Systems
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• v.2 no.4
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• pp.177-180
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• 2013

A software birthmark means inherent characteristics that can be used to identify a program. Because the software birthmark is difficult to remove by simple program transformation, it can be used to detect code theft. In this paper, we propose a birthmark technique based on API k-gram of Android applications. Android SDK provides various libraries that help programmers to develop application easily. In order to use Android SDK, we have to use API method calls. The API call instructions are hard to be replaced or removed, so they can be a inherent characteristics of an application. To show the effectiveness of the proposed birthmark, we compared it with previous birthmarks and evaluated it with open source applications. From the experiments, we verified that the credibility and resilience of our birthmark is higher than previous birthmarks.

• The KIPS Transactions:PartC
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• v.8C no.6
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• pp.703-710
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• 2001

In this paper, we consider a multiple watermarking for image copyright protection. Multiple watermarking can be defined that two or more watermarks are inserted into the same content. Multiple watermarking using spread spectrum technique is able to extract the correct watermarks from the watermarked content when the orthogonality among keys should be guaranteed only. To keep the orthogonal property between keys, we perform the process of Gram-Schmidt on the random sequences. The orthogonalized sequences are used as keys to embed the watermarks. The proposed method can not only extract correctly the embedded watermarks but also show the robustness against various attacks such as Gaussian noise addition, histogram equalization, gamma correlation, sharpening and brightness/contrast adjustment.

• Korean Journal of Veterinary Service
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• v.20 no.2
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• pp.151-159
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• 1997

This study was carried out to isolate of causative agents from CMT-positive and mean somatic cell count(SCC) $\geq$500,000 cells/ml mastitic milk, and evaluate to antimicrobial susceptibility of isolates in Iksan branch area from January to November, 1996. 1. The CMT-positivity(SCC 500,000 cells/ml) of 610 heads was 36.2% (221), and of 2,373 quarter milks was 16.1% (383). 2. The Gram-positive isolates were 153 strains which was Staphylococcus sp (115), Micrococcus sp (18), Streptococcus sp (10), Listeria monocytogenes (5) and Enterococcus faecalis(5). 3. The Gram-negative isolates were 66 strains including E coli(14), Yersinia sp (13), Shigella sp(8), Enterobacillus sp(8), Cedecea sp(5), Pseudomonas aeruginosa(5), Proteus sp(5), Klebsiella sp(4), Salmonella sp(2), kluyvera ascorbate(1) and Tatumella ptyseos (1). 4. The Gram positive strains of isolates were moderately susceptible to T/s, Cp, Fd, Imp, Aug, Rif, Cft and Va. And the Gram negative strains of Isolates were moderately susceptible to T/s, Cp, Imp, Pi and Ti, In order. 5. Multiple antimicrobial resistant patterns were encountered 62 and 36 from Gram positive and negative isolates, respectively.

• Pediatric Infection and Vaccine
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• v.4 no.1
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• pp.79-89
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• 1997

Purpose : Neonatal bacterial meningitis is the disease which clinical manifestations are nonspecific and several neurologic complications may occur. We studied neonatal bacterial meningitis, particularly in treatment and prognosis according to causative organisms -gram positive and gram negative bacteria- to assist in treatment of neonatal bacterial meningitis. Methods : We analysed twenty-four cases retrospectively who had been admitted in NICU or pediatric ward in Chung-ang Gil hospital from Jan. 1991 to Jun. 1996, and who had proven causative organisms in culture or latex agglutination[n test in CSF. Results : 1) The ratio of male to female was 2.4: 1. The mean birth weight and gestational age in cases with gram positive bacterial meningitis were $2.91{\pm}0.79kg$ and $38.4{\pm}2.74$ weeks and those in cases with yam negative bacterial meningitis were $3.30{\pm}0.90kg$ and $37.7{\pm}3.33$weeks respectively. There was no significant difference between the two groups. 2) The perinatal predisposing factors were pematurity, mecoinium staining amnionic fluid, matemal diabetes and pregnancy-induced hypertension, etc. The clinical manifestations Were fever, seizure, poor oral intake and fontanel bulging, etc. There were eleven cases with early onset bacterial meningitis(four cases by gram positive bacteria, seven cases by gram negative bacteria), and thirteen cases with late onset bacterial meningitis(seven cases by gram positive bacteria, six cases by gram negative bacteria). There was no significant difference between the two groups in terms of onset. 3) There were eleven cases with yam positive bacterial meningitis and they were coagulase-negative staphylococci(three cases), group B streptococci(three cases), Staphylococcus aureus(two cases), Streptococcus viridans(two cases), and enterococci(one case). And there were thirteen cases with gram negative bacterial menir gitis and they were Escherichia coli(seven cases), Klevsiella pneumoniae(three cases), Pseudomonas aeruginosa(one case), Acinetobactor(one case) and Enterobacter(one case). 4) The initial CSF WBC counts in cases with yam negative bacterial meningitis were significantly higher than those in cases with gram positive bacterial meningitis but the CSF protein and glucose levels were no significant difference in the two groups statistically. 5) The number of cases with abnormal findings in brain ultrasonography was seven in gram positive bacterial meningitis and ten in gram negative bacterial meningitis. 6) There were relatively high sensitivity to penicillin derivatives, the first generation cephalosporin and vancomycin in gram positive bacteria and to the third generation cephalosporin and amikacin in gram negative bacteria. 7) The mortality rate was 20.8%(5 cases were expired or discharged hopelessly). There was no significant difference between the two groups in prognosis. Conclusions : We recommend active treatment in noenatal bacterial meningitis to improve prognosis because the prognosis is poor.

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2002.11a
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• pp.412-416
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• 2002

멀티미디어 검색 시스템들은 아직까지 내용 기발에 의한 검색기술이 실용적으로 쓰일 만큼 높은 성능을 보이고 있지 않기 때문에 텍스트에 의한 검색만을 지원하고 있는 실정이다. HTML 문서에 나타나는 텍스트 중 이미지 아래에 붙은 표제나 이미지 링크에 붙어 있는 텍스트를 골라내어 이미지의 색인 정보로 이용하여 텍스트를 추출하는 기법을 제안하였다. 텍스트를 추출하기 위해 N-Gram 색인 방법을 사용하였으며 한편 검색 효율을 높이기 위해서 질의 의도가 큰 단어에 가중치를 부여하였다.

• YAKHAK HOEJI
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• v.10 no.4
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• pp.7-20
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• 1966

1. Of the 32 extracts from Genus of lishenes broth tested for antimicrobial activity, 28 inhibited at least one of the 3 test microorganisms used. 2. Twenty seven lichnes broth from 32 species tested were active against at least one of the Gram-positive bacteria M. pyogenes var, aureus 203 p, and twenty four lichenes broth from 32 Species tested were active against at least one of the Gram-positive bacteria Bacillus subtilis ATCC 6633. 3 Twenty five lichenes broth from 32 species tested were active against at least one of the Gram-negative bacteria Escherichia coli 0.126. 4. The antibiotic substances in lichenes were readily extracted by organic solvents.

• Proceedings of the Korean Information Science Society Conference
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• 2000.04b
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• pp.324-326
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• 2000

본 논문에서는 항공편 예약이라는 제한 영역에서의 연속음성인식 시스템을 위한 후처리 본 논문에서는 항공편 예약이라는 제한 영역에서의 연속음성인식 시스템을 위한 후처리 방안을 제시한다. 제안하는 후처리 방안은 200 문장의 항공편 예약 텍스트 데이터를 이용하여 문형 정보를 추출한 뒤 특정 문형별로 분류하였다. 분류된 문형과 음성인식 후의 문장을 비교하여 가장 유사한 문형을 추론한다. 추론한 특정 문형에서 나올 수 있는 형태소를 형태소들간의 N-gram 정보가 수록된 데이터베이스를 이용하여 형태소를 수정하고 보완한 결과를 최종 문장으로 출력한다.

• Korean Journal of Pharmacognosy
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• v.18 no.1
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• pp.1-4
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• 1987

The methanol and benzene extracts of the leaves of 55 higher plants in Korea were tested for their antibacterial activity against three Gram positive bacteria, Streptococcus mutans, Staphylococcus aureus and Bacillus subtilis, and one Gram negative bacterium Escherichia coli. Among them, the methanol extract of the leaves of Liriodendron tulipifera showed remarkably potent antibacterial activity against both Gram positive and negative bacteria.