• Title/Summary/Keyword: Grading system

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Survival of Patients with Prostate Cancer in Yazd, Iran

  • Zahir, Shokouh Taghipour;Nazemian, Mohammad Reza;Zand, Sanaz;Zare, Samad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.883-886
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    • 2014
  • Background: Prostate cancer is the second leading cause of cancer death in men worldwide. Several factors such as availability of screening tests, and dietary, other lifestyle, environmental and genetic influences contribute to worldwide disparities in prostate cancer incidence and mortality rates. Our aims were to investigate patient characteristics at the time of diagnosis, common treatment strategies employed and survival in an Iranian male population with prostate cancer. Materials and Methods: Archives of Pathology Departments of five referral centers affiliated with the School of Medicine of Shahid Sadoughi University in Yazd province were reviewed. Paraffin-embedded blocks were reviewed by two independent pathologists to confirm the diagnosis. The latest modification of the Gleason Scoring System was adopted to determine pathological grading. Following pathological evaluation, patients were contacted via telephone to acquire information regarding their current status. Results: Pathology blocks were available for 113 patients. However, upon phone contacts, we were unable to determine the survival status in 23 patients (response rate=83%). Therefore, 90 patients were enrolled in the final analysis. The median follow-up time was 6.0 years (ranging from 0.3 to 8.8 years). There were 30 death attributed to prostate cancer in the study group. Kaplan-Meier analysis revealed that patient age at the time of diagnosis was a significant predictor of survival. Another significant predictor of poorer survival was higher tumor grade. Conclusions: Our observations indicate that age and pathological grade can negatively affect survival of individuals with prostate cancer in Iran.

Arthroscopic Bankart Repair using Suture Anchors (봉합나사를 이용한 Bankart 병변의 관절경적 봉합술)

  • Kim, Kyung-Taek;Kim, Chul-Hong;Shin, Sang-Howa;Kwak, Jong-Ill
    • Journal of the Korean Arthroscopy Society
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    • v.10 no.2
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    • pp.173-177
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    • 2006
  • Purpose: To evaluate the efficacy of arthroscopic Bankart repair using suture anchors for treatment of traumatic anterior instability of shoulder joint. Materials and Methods: We performed arthroscopic Bankart repair using suture anchor in 90 cases and evaluated the results with the functional grading system of Rows and Zarins after patients were followed up for more than 24 months. Results: Combined pathologies identified under arthroscopy were Hill-sachs lesion in 46 cases, SLAP lesion in 12 cases, Rotate cuff lesion in 7 cases. The results were excellent or good in 82(91.1%) cases and redislocation was happened only 3 cases. Conclusion: We concluded that arthroscopic Bankart repair with suture anchors is one of the reliable and effective method for recurrent shoulder dislocation with Bankart lesion.

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Clinical Outcomes of Percutaneous Plasma Disc Coagulation Therapy for Lumbar Herniated Disc Diseases

  • Kim, Sang-Hyun;Kim, Sung-Chul;Cho, Ki-Hong
    • Journal of Korean Neurosurgical Society
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    • v.51 no.1
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    • pp.8-13
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    • 2012
  • Objective : This is prospective study of clinical outcomes of percutaneous plasma disc coagulation Therapy (PDCT) in patients with herniated lumbar disc disease (HLD) to evaluate the safety and efficacy in its clinical application and usefulness as a reliable alternative to microscopic discectomy. Methods : Forty-six patients were enrolled in this study from April 2006 to June 2010. All patients had one-level HLD. Disc degeneration was graded on routine T2-weighted magnetic resonance Image (MRI) using the Pfirrmann's grading system and all index levels were grade 3 and grade 4. Indications for surgery were radiculopathy caused by disc protrusion with soft consistency. MRI was done at one month after the procedure in all patients to check post-PDCT change. The clinical outcomes were evaluated using Visual Analog Scales (VAS) score and MacNab's criteria. Results : This study was approved by the Institutional Review Board of our institution. The age of the study population ranged from 16 to 59 years with a mean age of 37.2 years. There were 29 males and 17 females in this study. The mean period of clinical follow-up was 21 months. The average preoperative VAS score for radiculopathy was $7.4{\pm}1.4$, while the final follow-up VAS score was $1.4{\pm}0.7$ (p<0.001). In MacNab's criteria, 41 patients (89.1%) had achieved favorable improvement (excellent and good) until later follow-up. There were one patient from infection and two patients who needed to convert to open discectomy. Conclusion : PDCT is a safe and efficient treatment modality in a selective patient with HLD.

Influencing Factors Analysis of Facial Nerve Function after the Microsurgical Resection of Acoustic Neuroma

  • Hong, WenMing;Cheng, HongWei;Wang, XiaoJie;Feng, ChunGuo
    • Journal of Korean Neurosurgical Society
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    • v.60 no.2
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    • pp.165-173
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    • 2017
  • Objective : To explore and analyze the influencing factors of facial nerve function retainment after microsurgery resection of acoustic neurinoma. Methods : Retrospective analysis of our hospital 105 acoustic neuroma cases from October, 2006 to January 2012, in the group all patients were treated with suboccipital sigmoid sinus approach to acoustic neuroma microsurgery resection. We adopted researching individual patient data, outpatient review and telephone followed up and the House-Brackmann grading system to evaluate and analyze the facial nerve function. Results : Among 105 patients in this study group, complete surgical resection rate was 80.9% (85/105), subtotal resection rate was 14.3% (15/105), and partial resection rate 4.8% (5/105). The rate of facial nerve retainment on neuroanatomy was 95.3% (100/105) and the mortality rate was 2.1% (2/105). Facial nerve function when the patient is discharged from the hospital, also known as immediate facial nerve function which was graded in House-Brackmann : excellent facial nerve function (House-Brackmann I-II level) cases accounted for 75.2% (79/105), facial nerve function III-IV level cases accounted for 22.9% (24/105), and V-VI cases accounted for 1.9% (2/105). Patients were followed up for more than one year, with excellent facial nerve function retention rate (H-B I-II level) was 74.4% (58/78). Conclusion : Acoustic neuroma patients after surgery, the long-term (${\geq}1year$) facial nerve function excellent retaining rate was closely related with surgical proficiency, post-operative immediate facial nerve function, diameter of tumor and whether to use electrophysiological monitoring techniques; while there was no significant correlation with the patient's age, surgical approach, whether to stripping the internal auditory canal, whether there was cystic degeneration, tumor recurrence, whether to merge with obstructive hydrocephalus and the length of the duration of symptoms.

Correlation between Low Gleason Score and Prostate Specific Antigen Levels with Incidence of Bone Metastases in Prostate Cancer Patients: When to Omit Bone Scans?

  • Sanjaya, I. Putu Gde;Mochtar, Chaidir Arief;Umbas, Rainy
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4973-4976
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    • 2013
  • Background: To identify correlation and incidence of bone metastases in prostate cancer patient with low Gleason scores (GS) and prostate specific antigen (PSA) levels. Materials and Methods: This descriptive restrospective study covered patients with prostate cancer in Cipto Mangunkusumo Hospital in 2006-2011. Of a total of 478, those who had PSA values, histological examination, and bone scan were included, resulting in 358 eligible cases. PSA values were measured using the sandwich electrochemiluminescent immunoassay. Histological examination was graded according to Gleason's grading system and divided into 3 categories: well differentiated ($GS{\leq}6$), moderately differentiated (GS 7) and poorly differentiated (GS 8-10). Bone scans were performed using a radiopharmaceutical agent ($T_c$ 99m methylenen diphosphonate) with images captured by gamma camera. Results: The mean age was $67.5{\pm}7.8$, mean GS was $7.7{\pm}1.3$ and median PSA was 56.9 (range: 0.48-17000 ng/mL). There were 11 patients (3.0%) with positive bone scan with PSA<20 ng/mL and GS<8. Furthermore, there were 2 patients (0.6%) with $GS{\leq}6$ and PSA<10 ng/mL showing bone metastasis. Conclusions: In our study, there were still small percentage of patients with bone metastasis even when low values of PSA (PSA<10 ng/mL) and GS ($GS{\leq}6$) were applied.

The Effects of Admission Care on Bell's Palsy-Case Control Study (환자 대조군 연구를 통한 입원치료가 구안와사에 미치는 영향)

  • Son, In-Seok;Seo, Jung-Chul;Cho, Tae-Sung;Kwon, Hae-Yon;Youn, Hyoun-Min;Jang, Kyung-Jeon;Song, Choon-Ho;Ahn, Chang-Beohm
    • Journal of Acupuncture Research
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    • v.19 no.2
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    • pp.201-210
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    • 2002
  • Objective : The aim of this study was to assess the effects of admission care on Bell's palsy by case control study. Method : 27 patients who diagnosed as Bell's palsy were shared 13 inpatients group treated by early admission care, and 14 outpatients group. They were equally treated with acupuncture, herb medicine and western medicine. The groups were evaluated by Yanagihara,s unweighted grading system at pre-treatment, after 5 days, after 10 days and after 15 days. Results : The Yanagihara,s scores of 2 groups showed stastically significant improvement in comparison with pre-treatment. In improvement index after treatment, the Yanagihara,s scores of 2 groups increased but were not stastically significant the difference. Conclusion : These results provided that the admission care may not be a valuable treatment for Bell's palsy. Further study is needed to evaluate the effect of early admission care on Bell's palsy.

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Comparison of Efficacy between Acupuncture Treatment and Collaborative Treatment with Prednisolone on Acute Bell's Palsy (급성 Bell's Palsy의 침 치료와 Prednisolone을 병행한 협진 치료의 효과 비교)

  • Yi, Joo-Il;Kim, Hae-Jin;Ryu, Eun-Kyung
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.3
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    • pp.125-132
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    • 2013
  • Objectives The purpose of this study was to compare the effects of acupuncture treatment with those of collaborative treatment regarding acute Bell's palsy. Methods Twenty-six patients who received outpatient treatment between March 2012 and February 2013 were divided into 2 groups. The East-West treatment group (EW group, n=12) received prednisolone and then acupuncture afterwards. The Eastern treatment group (E group, n=14) received just acupuncture. Acupuncture was administered 3 to 4 times a week, and both groups were educated to practice facial muscle exercises at home. Evaluations were made before treatment, after 1 week, 2 weeks, and 3 weeks using the House-Brackmann facial nerve grading system. Results Compared to before treatment, the House-Brackmann grades of both EW and E groups after 1, 2 and 3 weeks of treatment significantly decreased (p<0.05). Regarding group comparison, the House-Brackmann grade of the EW group was significantly lower than the E group at 1 week (p=0.043), but there was no significant difference at 2 and 3 weeks. Regarding improvement of House-Brackmann grades, there was no significant difference between the two groups at 1, 2 and 3 weeks (p>0.05). Conclusions Compared to just acupuncture treatment, collaborative treatment with prednisolone significantly improved the House-Brackmann grade after 1 week, but there was no difference as time passed. Because early intervention determines the prognosis of Bell's palsy, collaborative treatment at the early stage will be clinically helpful to patients.

Inspection for Inner Wall Surface of Communication Conduits by Laser Projection Image Analysis (레이저 투영 영상 분석에 의한 통신 관로 내벽 검사 기법)

  • Lee Dae-Ho
    • Journal of Korea Multimedia Society
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    • v.9 no.9
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    • pp.1131-1138
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    • 2006
  • This paper proposes a novel method for grading of underground communication conduits by laser projection image analysis. The equipment thrust into conduit consists of a laser diode, a light emitting diode and a camera, the laser diode is utilized for generating projection image onto pipe wall, the light emitting diode for lighting environment and the image of conduit is acquired by the camera. In order to segment profile region, we used a novel color difference model and multiple thresholds method. The shape of profile ring is represented as a minimum diameter and the Fourier descriptor, and then the pipe status is graded by the rule-based method. Both local and global features of the segmented ring shaped, the minimum diameter and the Fourier descriptor, are utilized, therefore injured and distorted pipes can be correctly graded. From the experimental results, the classification is measured with accuracy such that false alarms are less than 2% under the various conditions.

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Preoperative Identification of Facial Nerve in Vestibular Schwannomas Surgery Using Diffusion Tensor Tractography

  • Choi, Kyung-Sik;Kim, Min-Su;Kwon, Hyeok-Gyu;Jang, Sung-Ho;Kim, Oh-Lyong
    • Journal of Korean Neurosurgical Society
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    • v.56 no.1
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    • pp.11-15
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    • 2014
  • Objective : Facial nerve palsy is a common complication of treatment for vestibular schwannoma (VS), so preserving facial nerve function is important. The preoperative visualization of the course of facial nerve in relation to VS could help prevent injury to the nerve during the surgery. In this study, we evaluate the accuracy of diffusion tensor tractography (DTT) for preoperative identification of facial nerve. Methods : We prospectively collected data from 11 patients with VS, who underwent preoperative DTT for facial nerve. Imaging results were correlated with intraoperative findings. Postoperative DTT was performed at postoperative 3 month. Facial nerve function was clinically evaluated according to the House-Brackmann (HB) facial nerve grading system. Results : Facial nerve courses on preoperative tractography were entirely correlated with intraoperative findings in all patients. Facial nerve was located on the anterior of the tumor surface in 5 cases, on anteroinferior in 3 cases, on anterosuperior in 2 cases, and on posteroinferior in 1 case. In postoperative facial nerve tractography, preservation of facial nerve was confirmed in all patients. No patient had severe facial paralysis at postoperative one year. Conclusion : This study shows that DTT for preoperative identification of facial nerve in VS surgery could be a very accurate and useful radiological method and could help to improve facial nerve preservation.

Association of Polymorphisms in the Bovine Leptin Gene with Ultrasound Measurements for Improving in Korean Cattle

  • Kong, H.S.;Oh, J.D.;Lee, S.G.;Hong, Y.S.;Song, W.I.;Lee, S.J.;Kim, H.C.;Yoo, B.H.;Lee, H.K.;Jeon, G.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.12
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    • pp.1691-1695
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    • 2006
  • The identification method that inflects real time ultrasound (RUT) and the potential application of marker assisted selection (MAS) for improvement of a cow population of Hanwoo (Korean Native cattle) was studied. The averages of RUT longissimus muscle area, RUT fat thickness, and RUT marbling score scanned at the 13th rib were 55.78 $cm^2$, 3.70 mm and 3.83 scores, respectively. We investigated the effects of the two SNPs (Kpn2 I and Msp I) in the leptin gene on carcass traits for Hanwoo cows by using ultrasound measurements. Genotype CC of the Kpn2 I had a significantly higher effect on back fat thickness (4.23 mm) and longissimus muscle area (57.57 $cm^2$) than genotype TT (3.14 mm, 53.93 $cm^2$, respectively, p<0.05). Genotype AA of the Msp I had a significantly higher effect only on marbling score (5.37) than genotype AB (3.57, p<0.05) and BB (3.37, p<0.05). Significant effects of SNPs in the leptin gene were found for the ultrasound measures of body composition in live cattle.