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Role of dexmedetomidine as adjuvant in postoperative sciatic popliteal and adductor canal analgesia in trauma patients: a randomized controlled trial

  • Ahuja, Vanita;Thapa, Deepak;Chander, Anjuman;Gombar, Satinder;Gupta, Ravi;Gupta, Sandeep
    • The Korean Journal of Pain
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    • v.33 no.2
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    • pp.166-175
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    • 2020
  • Background: The effect of dexmedetomidine as an adjuvant in the adductor canal block (ACB) and sciatic popliteal block (SPB) on the postoperative tramadol-sparing effect following spinal anesthesia has not been evaluated. Methods: In this randomized, placebo-controlled study, ninety patients undergoing below knee trauma surgery were randomized to either the control group, using ropivacaine in the ACB + SPB; the block Dex group, using dexmedetomidine + ropivacaine in the ACB + SPB; or the systemic Dex group, using ropivacaine in the ACB + SPB + intravenous dexmedetomidine. The primary outcome was a comparison of postoperative cumulative tramadol patient-controlled analgesia (PCA) consumption at 48 hours. Secondary outcomes included time to first PCA bolus, pain score, neurological assessment, sedation score, and adverse effects at 0, 5, 10, 15, and 60 minutes, as well as 4, 6, 12, 18, 24, 30, 36, 42, and 48 hours after the block. Results: The mean ± standard deviation of cumulative tramadol consumption at 48 hours was 64.83 ± 51.17 mg in the control group and 41.33 ± 38.57 mg in the block Dex group (P = 0.008), using Mann-Whitney U-test. Time to first tramadol PCA bolus was earlier in the control group versus the block Dex group (P = 0.04). Other secondary outcomes were comparable. Conclusions: Postoperative tramadol consumption was reduced at 48 hours in patients receiving perineural or systemic dexmedetomidine with ACB and SPB in below knee trauma surgery.

The survey on contents of preservative and general composition in cheese (치즈의 보존료 및 일반성분 함량 조사)

  • Han, Hye-Jin;Kim, Yoen-Joo;Lee, Kyung-Hye;Yun, Min;Kim, Young-Seob;Lee, Ju-Hyoung
    • Korean Journal of Veterinary Service
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    • v.37 no.3
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    • pp.191-196
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    • 2014
  • This study was conducted to compare the contents of preservatives and general composition on four different types of cheese to provide useful data and information to the consumer. We analyzed preservatives (sorbic acid, benzoic acid, dehydroacetic acid, methyl p-hydroxy benzoate, ethyl p-hydroxy benzoate, propionic acid) and general composition (moisture, protein, fat) from total 102 cheeses which are 46 sliced cheeses, 22 string cheeses, 20 cream cheeses and 14 pizza cheeses. Preservatives were detected from total 14 samples, which are suitable for the authorized limits in Korea. Sorbic acid was detected from 13 samples (197.3~1,736.1 mg/kg) and propionic acid was detected from 1 sample (362.7 mg/kg). Considering from each type of cheese, cream cheese showed the high detection rate (60%); 12 samples of cream cheese contained sorbic acid. The moisture, protein and fat contents of cheeses were in the ranges of 44.3~56.8%, 7.2~24.6% and 19.6~26.8%. Cream cheese had the highest level of moisture (56.8%) and fat (26.8%), but protein level is very low (7.2%).

Determination of 4-Methylimidazole and 2-Acetyl-4(5)-tetrahydroxybutylimidazole in Caramel Color and Processed Foods by LC-MS/MS

  • Kim, Tae Rang;Kim, Su Un;Shin, Young;Kim, Ji Young;Lee, Sang Me;Kim, Jung Hun
    • Preventive Nutrition and Food Science
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    • v.18 no.4
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    • pp.263-268
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    • 2013
  • In this study, the quick HPLC-MS/MS method for the simultaneous separation of 2-acetyl-4(5)-tetrahydroxybuthylimidazole (THI) and 4-(5)-methylimidazole (4-MI) in alkaline medium was used for caramel color and processed foods in Korea. After a simple sample pretreatment, 51 4-MI-labeled samples were positive for 4-MI and 2 also contained THI. The concentration of 4-MI was 260.5~24, $499.3{\mu}g/kg$ in caramel color, less than $LOD{\sim}1,712.5{\mu}g/kg$ in sauce, 1,242.3, $5,972.2{\mu}g/kg$ in balsamic vinegar, $2,118.3{\sim}5,802.4{\mu}g/kg$ in complex seasoning, $82.7{\sim}5,110.6{\mu}g/kg$ in curry, and $29.9{\sim}464.4{\mu}g/kg$ in soft drinks. The recovery rate of 4-MI was 97.1~111.0% in sauce and 81.9~110.0% in powder and that of THI was 83.6{\sim}106.4% in sauce and 61.2{\sim}99.4% in powder. Our results concluded a safe amount of 4-MI and THI compared to the limit of Korea additive code but the processed foods do not have a limit of caramel color and 4-MI in Korea. Therefore, research and monitoring of 4-MI and THI is needed for processed foods in Korea.

Perinatal outcome and possible vertical transmission of coronavirus disease 2019: experience from North India

  • Sharma, Ritu;Seth, Shikha;Sharma, Rakhee;Yadav, Sanju;Mishra, Pinky;Mukhopadhyay, Sujaya
    • Clinical and Experimental Pediatrics
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    • v.64 no.5
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    • pp.239-246
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    • 2021
  • Background: The consequences of severe acute respiratory syndrome corona virus 2 on mother and fetus remain unknown due to a lack of robust evidence from prospective studies. Purpose: This study evaluated the effect of coronavirus disease 2019 (COVID-19) on neonatal outcomes and the scope of vertical transmission. Methods: This ambispective observational study enrolled pregnant women with COVID-19 in North India from April 1 to August 31, 2020 to evaluate neonatal outcomes and the risk of vertical transmission. Results: A total of 44 neonates born to 41 COVID-19-positive mothers were evaluated. Among them, 28 patients (68.3%) (2 sets of twins) were delivered within 7 days of testing positive for COVID-19, 23 patients (56%) (2 sets of twins) were delivered by cesarean section; 13 newborns (29.5%) had low birth weight; 7 (15.9%) were preterm; and 6 (13.6%) required neonatal intensive care unit admission, reflecting an increased incidence of cesarean delivery and low birth weight but zero neonatal mortality. Samples of cord blood, placental membrane, vaginal fluid, amniotic fluid, peritoneal fluid (in case of cesarean section), and breast milk for COVID-19 reverse transcription-polymerase chain reaction tested negative in 22 prospective delivery cases. Nasopharyngeal swabs of 2 newborns tested positive for COVID-19: one at 24 hours and the other on day 4 of life. In the former case, biological samples were not collected as the mother was asymptomatic and her COVID-19 report was available postdelivery; hence, the source of infection remained inconclusive. In the latter case, all samples tested negative, ruling out the possibility of vertical transmission. All neonates remained asymptomatic on follow-up. Conclusion: COVID-19 does not have direct adverse effects on the fetus per se. The possibility of vertical transmission is almost negligible, although results from larger trials are required to confirm our findings.

The Characteristics and Limitations of 'Automatic Submission of Budget Bills to Plenary Session', Article 85-3 of the National Assembly Act (국회법 예산안 자동부의제의 성격과 한계)

  • Jung, Jinwung
    • Korean Journal of Legislative Studies
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    • v.24 no.1
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    • pp.103-133
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    • 2018
  • This paper examines whether the budget making process has improved since the Automatic Submission of Budget Bills to Plenary Session Act was enacted. The budget bill was passed before the Dec. 2 deadline from 2014 to 2016. Several researchers, therefore, concluded that the clause is in favor of the ruling party and the majority party. However, this study confirmed that the argument is valid only under the condition of unified government. In other cases, the government party can have a limited impact on the budget-review process, and the aspects of the budget screening process are similar to those before the Act was enforced. Under the conditions of the divided government and two-party system, it is difficult that the budget bill is passed by the legal deadline. In the case of the divided government and multi-party system without majority party, the third party exerts a very significant influence on the budget-review process.

A Study on the Management and Improvement of Library Ordinances in Lower Tier Governments (기초자치단체의 도서관조례 운영현황 및 개선방안 연구)

  • Joung, Hyuntae;Jung, Miyeun
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.24 no.1
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    • pp.105-122
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    • 2013
  • It was examined that library-related ordinances enacted by local governments in nationwide were all 321 cases. Among them, the library management ordinance(185 cases, 57.6%) is the most common, small library ordinance(54 cases, 16.8%), Saemaeul mobile library ordinance(24 cases, 7.5%), reading promotion ordinance(29 cases, 9.0%), other ordinances(29 cases, 9.0%), such as the order was followed. Since 1996, the local government system was carried out in earnest, library ordinances each year continues to increase. Saemaeul mobile library ordinances was enacted primarily in the 1990s, small library ordinances and reading promotion ordinances have been increasing rapidly since 2009. In order to clarify the purpose of the ordinances, the term 'library' should be included in the title. It is suggested that the library-related ordinances in a local government, such as public library ordinance, small library ordinance, Saemaeul mobile library ordinance, and reading promotion ordinance, are better be integrated for consistent implementations of library policies.

Study on Water Quality of Spring Water in Seoul (서울지역 약수터의 수질특성에 관한 연구)

  • Kim, Kwang-Rae;Gil, Hae-Kyung;Kim, Hyun-Kook;Kim, Eun-Sook;Roh, Bang-Sik;Hong, Ju-Hee;Lee, Jin;Kim, Jeong-Yeon;Lee, Man-Ho;Eom, Seok-Won;Lee, Jai-Young
    • Journal of Soil and Groundwater Environment
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    • v.15 no.6
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    • pp.99-106
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    • 2010
  • We investigated springs in Seoul in 2009 to know the change of water quality according to storage method of spring water, the concentration of chemical compounds and their correlation. Even spring water that originally satisfied national standard for drinking water could be exceeded national standard for drinking water by storage method such as storage bottle, temperature and period; especially used PET bottles could affect the increase of total colony counts. Therefore, spring water is desirable to be consumed on the spot, or to be stored in sterilized bottles in refrigerator rather than room temperature at home, and also to be consumed shortly not exceeding 24 hours. Total colony counts, coliform, yersinia, $F^-$, $Cl^-$, $NO_3^--N$, hardness, total Solids, pH, color and Al were exceeded national standard for drinking water at some springs. The result of correlation analysis shows that hardness and total solids, which are caused by several ionic compounds, had relatively high correlations with other chemical compounds.

A Study on the Efficient Measurement of Airborne Asbestos Concentrations at Demolition Sites of Asbestos Containing Buildings, etc. in Seoul (서울시내 석면함유 건축물 철거 현장 등에서의 효과적인 공기 중 석면농도 측정을 위한 연구)

  • Lee, Jinhyo;Lee, Suhyun;Kim, Jeongyeun;Kim, Jihui;Chung, Sooknye;Kim, Jina;Oh, Seokryul;Kim, Iksoo;Shin, Jinho;Eo, Soomi;Jung, Kweon;Lee, Jinsook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.2
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    • pp.113-121
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    • 2014
  • Objectives: This study is intended to seek credible and efficient measurements on airborne asbestos concentrations that allow immediate action by establishing complementary data through comparative analysis with existing PCM and KF-100 method real-time monitoring equipment in working areas in Seoul where asbestos-containing buildings are being demolished, including living environment surroundings. Materials: We measured airborne asbestos concentrations using PCM and KF-100 at research institutes, monitoring networks, subway stations and demolition sites of asbestos-containing buildings. Through this measurement data and KF-100 performance testing, we drew a conversion factor and applied it via KF-100. Finally we verified the relationship between PCM and KF-100 with statistical methods. Results: The airborne asbestos concentrations by PCM for the objects of study were less than the detection limit(7 fiber/$mm^2$) in three (20%) out of 15 samples. The highest concentration was 0.009 f/cc. The airborne asbestos concentrations by PCM in laboratories, monitoring networks, subway stations and demolition sites of asbestos-containing buildings were respectively $0.002{\pm}0.000$ f/cc, $0.004{\pm}0.001$ f/cc, $0.009{\pm}0.001$ f/cc, and $0.002{\pm}0.000$ f/cc. As a result of KF-100 performance testson rooftops, the conversion factor was 0.1958. Applying the conversion factor to KF-100 for laboratories, the airborne asbestos concentrations ratio of the two ways was nearly 1:1.5($R^2$=0.8852). Also,the airborne asbestos concentration ratio of the two ways was nearly 1:1($R^2$=0.9071) for monitoring networks, subway stations, and demolition sites of asbestos-containing buildings. As a result of independent sample t-tests, there was no distinction between airborne asbestos concentrations monitored in the two ways. Conclusions: In working areas where asbestos-containing buildings are being demolished, including living environment surroundings, quickly and accurately monitoring airborne asbestos scattered in the air around the working area is highly important. For this, we believea mutual interface of existing PCM and a real-time monitoring equipment method is possible.

A study on a reconstruction of Gwanghwamun and fluctuation of boulevard in front of Gwanghwamun (1960년대 광화문 중건과 광화문 앞길의 변화)

  • Kang, Nan-hyoung;Song, In-Ho
    • Journal of architectural history
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    • v.24 no.4
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    • pp.7-18
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    • 2015
  • Gwanghwamun was dismantled and displaced to the east side of the palace, at that time, the Chosun Government General Building was constructed in the Gyeongbokgung palace. After the Korea war, it remained as a stonework as a result of the fire. In 1968, The Gwanghwamun came back in front of the palace. Then, why it was rebuilt in the 3rd Republic period? What was the reason for selecting concrete? Since the May 16 coup, the military regime had been utilized palace and surrounding urban space to show a visible practice of modernization. Attempting the combination of modern technology in the 1960s and traditional cultural property and reconstructing a city as a pretext called Cultural Heritage conservation was a typical mechanism of the 1960s. In this study, I start by assume that reconstructing Gwanghwamun(1968) was a part of project to change the surrounding urban space of Gwanghwamun than to preserve cultural assets. Two main contributions of the study are following. First, I collect availabe data on the reconstructing surrounding urban space of the Gwanghwamun and re-organize them in chronological order to make them as fragments of a map. Second, I analysis and identify the nature and phase of the Gwanghwamun reconstruction.

A survey of the opinions of sewing company managers on the present conditions of the sewing industry and the government's policy on support (의류 봉제업 경영인의 봉제산업 현황과 정부 지원에 관한 의견 조사)

  • Choi, Sunyoon
    • The Research Journal of the Costume Culture
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    • v.24 no.2
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    • pp.150-165
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    • 2016
  • With signs of the redevelopment of the domestic sewing industry, national support agencies were established. This study aims to assess the present conditions of the domestic sewing industry and investigate the effectiveness of national sewing industry support policies. According to the results of a survey of 30 sewing companies managers, the biggest factor causing product defects was work being rushed because of tight delivery dates, and the reduction in sales was caused by a lack of orders. Moreover, sewing technicians are aging, and the biggest reason for their decrease in number is that people do not pursue the job because of the common understanding that it is difficult. Managers perceived that the government's sewing technician training program was not a practical help. They were well aware of the support program to improve the work environment and the sewing equipment support program and showed high satisfaction with these programs, but they complained that the period for equipment rental was fixed. A majority of them thought that the Korean sewing industry environment had still not improved, and were skeptical about its future outlook. They identified its most urgent needs as the expansion of orders and the securing of manpower. The support programs that they wanted urgently included support for employees' four major public insurances and the enactment of the increase of toll processing fees.