• 융합보안논문지
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• 제17권2호
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• pp.53-68
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• 2017

오늘날 정보공유는 점차 지능화, 고도화되어 나타나고 있는 사이버공격을 효과적으로 예방할 수 있는 수단으로 인식되어 미국, EU, 영국, 일본 등 전세계적으로 국가적 차원의 사이버 위협정보 공유체계를 구축하고 있다. 특히 미국은 지난 2015년 12월 "사이버위협정보공유법(CISA)"을 제정하는 등 오래전부터 위협정보 공유를 위한 법 제도 기반 마련, 수행체계 구축 이행을 추진해오고 있다. 우리나라는 국가사이버안전센터와 한국인터넷진흥원을 중심으로 각각 공공, 민간분야에서 사이버 위협정보를 수집, 공유하고 있으며 관련 법 제도의 도입 시행을 통한 일원화된 정보공유 절차의 마련과 수행체계 구축을 추진 중에 있으나, 사이버 위협정보 공유 과정에서 발생할 수 있는 기업 또는 개인의 민감정보 유출문제, 정보수집 관리 주체에 대한 신뢰, 효용성 등의 문제의 우려도 제기되고 있는 실정이다. 본 논문에서는 미국과 우리나라의 사이버 위협정보 공유 현황의 비교 분석을 통해 향후 우리나라의 성공적인 사이버 위협정보 공유 체계정착이 이루어지는데 필요한 요구사항 및 시사점을 도출해보고자 한다.

• The Korean Journal of Pain
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• 제33권1호
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• pp.40-47
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• 2020

Background: Duloxetine is an antidepressant that is also useful in chronic neuropathic and central origin pain. In this study, the role of duloxetine in decreasing acute postoperative pain after lumbar canal stenosis surgery is explored. Methods: In this single center, triple blinded, and placebo-controlled trial, 96 patients were randomized for statistical analysis. The intervention group received oral duloxetine 30 mg once a day (OD) for 2 days before surgery, 60 mg OD from the day of surgery to the postoperative second day and 30 mg OD for the next 2 days (a total duration of 7 days). A placebo capsule was given in the other group for a similar time and schedule. The same standard perioperative analgesia protocols were followed in both groups. Results: Total morphine consumption up to 24 hours was significantly decreased in the duloxetine group (P < 0.01). The time to the first analgesia requirement was similar in both groups but the time to the second and third dose of rescue analgesia increased significantly in the duloxetine group. The time to ambulation was decreased significantly (P < 0.01) in the duloxetine group as compared to the placebo group. Pain scores remained similar during most of the time interval. No significant difference was observed in the complication rate and patient satisfaction score recorded. Conclusions: Duloxetine reduces postoperative pain after lumbar canal stenosis surgery with no increase in adverse effects.

• 대한교통학회지
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• 제33권6호
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• pp.531-542
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• 2015

우리나라의 철도산업 구조개혁 관련 논의는 1998년 철도청 경영진단을 시작으로 2005년 한국철도공사의 출범, 2013년 수서발 KTX 법인 면허 발급과 민영화 논란에 이르기까지 지속적으로 이루어져 왔다. 본 연구에서는 철도산업 구조개혁이 10년 이상의 장기성을 통해 이루어진 점에 비추어, 이러한 정책변동은 여러 외적 변수와 장기적인 정책주체들의 상호작용에 기인하여 이루어졌다고 보고, 옹호연합모형을 적용하여 고찰하고자 하였다. 철도산업 구조개혁은 연합(Coalition)간의 합의점을 도출하지 못한 채 정권교체 등의 시점에 보다 우월한 지배연합에 의해 정책이 추진되었다고 볼 수 있으며, 이러한 정책의 성공적인 집행을 위해서는 깊은 갈등관계 속에서의 상이한 정책선호와 도구들을 중재하고 절충할 수 있는 대안을 도출하는 정책중개자의 역할이 중요할 것으로 판단하였다.

• 기술혁신연구
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• 제7권1호
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• pp.36-59
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• 1999

Fundamental advances in the biotechnologies are exerting a profound influence on the health care, agricultural, industrial chemical, environmental, and other industrial fields. Korean government are now more and more realizing the importance of biotechnology as a main technology for the 21st century. But any technical progress is largely the result of a complex set of relationships among the firms, institutions and others involved in development. So understanding the complexity is very important to make promoting strategies and it is even critical in the field of biotechnology. The reason is that commercialization of research results in biotechnology is strongly related with the national science bases provided by academic and public institutes. And its applicable industrial sectors are very diverse. So it is very important to make a effective collaboration system among many R&D related agents. This article discusses and compares both USA and Japanese framework of national innovation systems in the field of biotechnology. The American Innovation system encourages basic research in the biological sciences, and fosters the creation of small venture firms that focus on the development of novel products. America's peculiar incentive structure, derived from its research and educational system, financial system, and regulatory environment has driven USA labs and firms to the forefront of many biotechnology fields. The Japanese institutional environment in contrast, supported the strategy of building production expertise. Firms were urged to use the new techniques as a way of leapfrogging into a second generation of bio-products, in that cost and production advantages count. But the strategy was not effective as expected and Japanese firms have remained competent but not prominent rivals. The differing situations in USA and Japan with regard to biotechnology have many suggestions for our bioindustry. In the conclusion of this article, we translate USA and Japan's experiences to some suggestions which guide for promoting Korea's biotechnology R&D and commercialization activities.

• 대한건축학회연합논문집
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• 제20권6호
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• pp.121-129
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• 2018

The present study analyzed what policies are being executed for deteriorated apartments in Japan and what characteristics each policy had in order to examine policy direction and implications for the improvement of vitalization of remodeling business of deteriorated apartments in Korea. The study results are as follows. Japan recognized social problems of deteriorated apartments and pushed forward a national level remodeling actively by preparing financial support of central government and supporting plan by city and province. First, Japan maintained initial performance of buildings through phased maintenance for deterioration of buildings and aimed to reduce environmental load and maintain asset values of buildings through enlarging durability of buildings by responding to lifestyle according to social changes. To this end, they promoted the long life of buildings through the establishment of systematic long term repair plan from the stage of moving in the buildings. Second, in order to reduce the risk of remodeling projects, they prepared an environment where business could be carried out with an easy mind in various aspects by introducing remodeling business registration system and large scale repair construction defect insurance system. Third, they reduced economic burden of main agents of remodeling business with tax preferential treatment and financial support policies. Fourth, they have established remodeling support system based on overall social issues and connected it with social effect that could be obtained through this. The remodeling policies of Japan were carried out in the direction of solving social problems and considering economic aspect rather than just improving individuals' residence environment.

• 지적과 국토정보
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• 제48권2호
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• pp.5-20
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• 2018

본 연구의 목적은 우리나라 아파트의 거래원인 가운데 하나인 분양권 거래비율을 중심으로 한 아파트 분양권 거래 실태와 지역 간 특성을 파악하는데 있다. 이를 위해 162개 시 군 지역을 중심으로 인구특성, 아파트거래 및 분양특성, 주거특성을 살펴보았으며 아파트 분양권 비율을 종속변수로 하는 다중회귀분석을 실시하였다. 그 결과 통계적으로 유의한 변수는 아파트 매매비율, 분양권 기타 소유권이전 비율, 아파트 거래회전율, 분양물량, 아파트 비율, 인구증가율, 아파트 매매 가격상승률로 나타났다. 아파트 매매가격 상승률에 있어서도 분양권 거래비율이 높은 지역에서 아파트 매매 가격 상승률은 상대적으로 낮게 나타났고 분양권 기타 소유권이전 건수가 상승할수록 아파트 분양권 거래건수도 상승하였다. 이에 본 결과로 아파트 시장에서 실수요자 중심의 거래를 활성화하기 위한 정부의 정책과 제도의 개선에 바탕이 되는 기초자료가 될 것으로 판단된다.

• 수완나부미
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• 제13권2호
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• pp.109-134
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• 2021

Indonesia has undergone the rapid deforestation largely as a result of practical consequences of human overexploitation of the forest. Between 1950 and 2015, around 43% of the forest area in Indonesia had been lost (68.0 million hectares). The process of deforestation has partly been a response to the rapidly intensifying 'global' and 'domestic' economic demands. Deforestation in Indonesia is also indirectly due to 'materialism-driven' value system and the corresponding weakening of Indonesian ethics. Therefore, given that socio-cultural expressions of modern Indonesian value systems have mostly taken place within a framework of Islam, the aim of the paper is to attempt to find Islamic ethics in general, which can provide the basis of ecological ethics to prevent rapid deforestation in Indonesia. The paper is composed of the followings. First, following the 'Introduction', it outlines the historical process of deforestation in Indonesia and also its corresponding socio-economic contexts. Then it moves on to talk about ecological ethics in general, thereby emphasizing that the phenomenological problem of deforestation needs to be conceived at a philosophical level beyond ecological phenomena. After discussing the ecological ethics, the paper proceeds to examine Islamic ethics as a canonical framework of ecological ethics in Indonesia. In doing so, it attempts to apply the Islamic ethics to the diverse Indonesian society and then considers 'Pancasila' as a potential framework for a pragmatic link between Islam ethics and Indonesian society. Having said that, in conclusion, the paper argues that there is a need for 'concrete' translation of 'Pancasila' into implementation in an Indonesian context, thereby various agents (government, policy-practitioners, concessionaires and also all the Indonesian) may agree in saying 'no' to overexploitation of the forest, to rapid depletion of the forest and to 'unsustainable' development practices.

• Journal of Audiology & Otology
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• 제23권2호
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• pp.69-75
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• 2019

Background and Objectives: The antioxidant ebselen will be able to limit or prevent the ototoxicity arising from 2-hydroxypropyl-β-cyclodextrin (HPβCD). Niemann-Pick Type C (NPC) disease is a disorder of lysosomal storage manifested in sphingolipidosis. Recently, it was noted that experimental use of HPβCD could partially resolve the symptoms in both animals and human patients. Despite its desirable effect, HPβCD can induce hearing loss, which is the only major side effect noted to date. Understanding of the pathophysiology of hearing impairment after administration of HPβCD and further development of preventive methods are essential to reduce the ototoxic side effect. The mechanisms of HPβCD-induced ototoxicity remain unknown, but the resulting pathology bears some resemblance to other ototoxic agents, which involves oxidative stress pathways. To indirectly determine the involvement of oxidative stress in HPβCD-induced ototoxicity, we tested the efficacy of an antioxidant reagent, ebselen, on the extent of inner ear side effects caused by HPβCD. Materials and Methods: Ebselen was applied prior to administration of HPβCD in mice. Auditory brainstem response thresholds and otopathology were assessed one week later. Bilateral effects of the drug treatments also were examined. Results: HPβCD-alone resulted in bilateral, severe, and selective loss of outer hair cells from base to apex with an abrupt transition between lesions and intact areas. Ebselen co-treatment did not ameliorate HPβCD-induced hearing loss or alter the resulting histopathology. Conclusions: The results indirectly suggest that cochlear damage by HPβCD is unrelated to reactive oxygen species formation. However, further research into the mechanism(s) of HPβCD otopathology is necessary.

• Journal of Animal Science and Technology
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• 제65권2호
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• pp.275-292
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• 2023

Nanotechnology in the food industry can increase the effectiveness of food ingredients. Nanotechnology can increase the bioavailability and absorption of bioactive compounds, enhance their stability, and improve the sensory quality of the product. Processed meat products are easily damaged due to bacterial activity. Advanced nanoemulsions as a meat preservative are nanoemulsions that can be used as preservative agents in meat products, particularly essential oil nanoemulsions, due to their antimicrobial and antioxidant properties. Its application is still limited to foods made from meat products. Therefore, this literature review examines nanoemulsion and its application in meat products and functionality improvement. Also, in the future, nanoemulsions in meat products must be made safe, and the government and businesses must work together to build consumer trust. It can be concluded that essential oil-based nanoemulsion has the potential to be used as an additive in meat products because it can kill bacteria, fight free radicals, improve flavor, and keep food fresh. Nanoemulsion is challenging in the meat industry because it can be toxic due to its tiny droplets (under 200 nm).

• 대한청각학회지
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• 제23권2호
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• pp.69-75
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• 2019

Background and Objectives: The antioxidant ebselen will be able to limit or prevent the ototoxicity arising from 2-hydroxypropyl-β-cyclodextrin (HPβCD). Niemann-Pick Type C (NPC) disease is a disorder of lysosomal storage manifested in sphingolipidosis. Recently, it was noted that experimental use of HPβCD could partially resolve the symptoms in both animals and human patients. Despite its desirable effect, HPβCD can induce hearing loss, which is the only major side effect noted to date. Understanding of the pathophysiology of hearing impairment after administration of HPβCD and further development of preventive methods are essential to reduce the ototoxic side effect. The mechanisms of HPβCD-induced ototoxicity remain unknown, but the resulting pathology bears some resemblance to other ototoxic agents, which involves oxidative stress pathways. To indirectly determine the involvement of oxidative stress in HPβCD-induced ototoxicity, we tested the efficacy of an antioxidant reagent, ebselen, on the extent of inner ear side effects caused by HPβCD. Materials and Methods: Ebselen was applied prior to administration of HPβCD in mice. Auditory brainstem response thresholds and otopathology were assessed one week later. Bilateral effects of the drug treatments also were examined. Results: HPβCD-alone resulted in bilateral, severe, and selective loss of outer hair cells from base to apex with an abrupt transition between lesions and intact areas. Ebselen co-treatment did not ameliorate HPβCD-induced hearing loss or alter the resulting histopathology. Conclusions: The results indirectly suggest that cochlear damage by HPβCD is unrelated to reactive oxygen species formation. However, further research into the mechanism(s) of HPβCD otopathology is necessary.