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Therapeutic effect of marine bioactive substances against periodontitis based on in vitro, in vivo, and clinical studies

  • Tae-Hee Kim;Se-Chang Kim;Won-Kyo Jung
    • Fisheries and Aquatic Sciences
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    • v.26 no.1
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    • pp.1-23
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    • 2023
  • Marine bioactive substances (MBS), such as phlorotannins, collagens, peptides, sterols, and polysaccharides, are increasing attention as therapeutic agents for several diseases due to their pharmacological effects. Previous studies have demonstrated the biological activities of MBS including antibacterial, anticoagulant, antidiabetic, antimicrobial, anti-inflammatory activities. Among numerous human diseases, periodontitis is one of the high-prevalence inflammatory diseases in the world. To treat periodontitis, several surgeries (bone grafting, flap surgery, and soft tissue graft) are usually used. However, the surgery for patients with chronic periodontitis induces several side effects, including additional inflammatory responses at the operated site, chronic wound healing, and secondary surgery. Therefore, this review assessed the most recent trends in MBS using Google Scholar, PubMed, and Web of Science search engines to develop marine-derived therapeutic agents for periodontitis. Further, we summarized the current applications and therapeutic potential of MBS to serve as a reference for developing novel technologies applied to MBS against periodontitis treatment.

Application of Topic Modeling Techniques in Arabic Content: A Systematic Review

  • Maram Alhmiyani;Huda Alhazmi
    • International Journal of Computer Science & Network Security
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    • v.23 no.6
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    • pp.1-12
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    • 2023
  • With the rapid increase of user generated data on digital platforms, the task of categorizing and classifying theses huge data has become difficult. Topic modeling is an unsupervised machine learning technique that can be used to get a summary from a large collection of documents. Topic modeling has been widely used in English content, yet the application of topic modeling in Arabic language is limited. Therefore, the aim of this paper is to provide a systematic review of the application of topic modeling algorithms in Arabic content. Using a well-known and trusted databases including ScienceDirect, IEEE Xplore, Springer Link, and Google Scholar. Considering the publication date from 2012 to 2022, we got 60 papers. After refining the papers based on predefined criteria, we resulted in 32 papers. Our result show that unfortunately the application of topic modeling techniques in Arabic content is limited.

The Role of Sungkyunkwan during the Joseon Dynasty and Implications for Modern Education in South Korea

  • Hyoyoung LEE
    • Journal of Koreanology Reviews
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    • v.3 no.1
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    • pp.23-29
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    • 2024
  • The present study has investigated and explored the role of Sungkyunkwan during the Joseon Dynasty and implications for modern education in South Korea using numerous literature dataset, such as google Scholar, Scopus, Web of Science. Sungkyunkwan had a significant role in the Joseon dynasty's academic, social and political life. They were known as Sungkyunkwan scholars and were the elite group with a significant controlling influence over the governmental structure. In addition, they influenced policy-making, judiciary, and culture preservation through their understanding and application of Confucianism. More specifically, the Sungkyunkwan graduates were appointed to serve in many administrative capacities in Hanyang and other city provinces, spreading the culture and beliefs of Sungkyunkwan throughout the kingdom. According to the prior study, South Korea faces the issues of modernity; however, the approaches brought by Sungkyunkwan and the concept of education that was adopted still have their relevance. Education in modern Korean society is closely connected with scholars; schools and universities are built to cultivate brilliant individuals with solid morals and values for society. The spirit of Sungkyunkwan, which is about diligence, perseverance, and ethical conduct, is still rooted in the Korean educational system.

Chyle leak after head and neck surgeries: a comprehensive review of diagnosis and management strategies

  • Aparna Ganesan;Nehal C. Singh;Naren P. Khatri;Charanjeet Singh Madaan;Savreek Kaur;Amanjot Kaur
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.50 no.1
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    • pp.3-12
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    • 2024
  • Chyle leaks are uncommon complications after head and neck surgeries. Although uncommon, such a complication is noteworthy mention due to its perplexing diagnosis and management strategies. This scoping review aims to highlight and emphasize the diagnosis and management options proposed in the literature. A comprehensive search was performed in PubMed, Google Scholar, Cochrane Library, and Scopus databases and identified 617 articles that were reduced to 40 studies and reports after applying the eligibility criteria. Although numerous treatment options ranging from simple, conservative measures to invasive surgical procedures have been mentioned for low-output, high-output, and massive leaks, there is no concrete evidence on the best method. Thus, a combination of management options must be customized by case for optimum results.

Artificial Intelligence as a Vehicle for Innovation: Literature Review and Bibliometric Study

  • Reema Khurana
    • Asia pacific journal of information systems
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    • v.32 no.4
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    • pp.916-944
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    • 2022
  • Artificial Intelligence has been a conceptual area for several decades. It has been studied extensively through experiments by the Information Systems community. When Information Systems supported with Information Technology became all pervasive in business and other allied areas, gradually the advancements in Artificial Intelligence also emerged as innovations across domains. Artificial Intelligence by definition is expected to substitute Human Intelligence, thereby making a huge space for innovation. In fact, all processes effected by human intelligence are liable to be replaced by AI which in itself is a massive innovation space. This paper will study the publication's repository (Scopus and Google Scholar from 1983 till 2021) in the area of Artificial Intelligence and innovation, then analyze the trend to gain insight into the evolution of AI as a vehicle for innovation.

Role of gene therapy in treatment of cancer for craniofacial regeneration-current molecular strategies, future perspectives, and challenges: a narrative review

  • Himanshu Singh
    • Journal of Yeungnam Medical Science
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    • v.41 no.1
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    • pp.13-21
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    • 2024
  • Gene therapy involves the introduction of foreign genetic material into host tissue to alter the expression of genetic products. Gene therapy represents an opportunity to alter the course of various diseases. Hence, genetic products utilizing safe and reliable vectors with improved biotechnology will play a critical role in the treatment of various diseases in the future. This review summarizes various important vectors for gene therapy along with modern techniques for potential craniofacial regeneration using gene therapy. This review also explains current molecular approaches for the management and treatment of cancer using gene therapy. The existing literature was searched to find studies related to gene therapy and its role in craniofacial regeneration and cancer treatment. Various databases such as PubMed, Science Direct, Scopus, Web of Science, and Google Scholar were searched for English language articles using the keywords "gene therapy," "gene therapy in present scenario," "gene therapy in cancer," "gene therapy and vector," "gene therapy in diseases," and "gene therapy and molecular strategies."

Pain Assessment in Nonverbal Older Adults with Dementia (언어적 의사소통이 어려운 치매환자에서의 통증 사정)

  • Kim, Hyun Sook;Yu, Su Jeong
    • Journal of Hospice and Palliative Care
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    • v.16 no.3
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    • pp.145-154
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    • 2013
  • This study was performed to evaluate the existing pain assessment methods including the tools developed for use with nonverbal older adults with dementia, and to suggest recommendations to clinicians based on the evaluations. Computerized literature searches published after year 2000 using databases - Google scholar, RISS, KoreaMed, Medline, ScienceDirect, CINAHL - were done. Searching keywords were 'pain', 'pain assessment', and 'cognitive impairment/dementia'. The pain assessments for non-communicative dementia patients who are unable to self-report their pains are often made using the assessment tools relying on the observation of behavioral indicators or alternatively the strategy of surrogate reporting. While several tools in English version and only one in Korean are suggested for the pain assessments based on the observation of behavioral indicators, none are commonly used. In this review, we selectively evaluated those tools known to show relatively higher degree of validity and reliability for nonverbal older adults with dementia, namely, CNPI, DOLOPLUS 2, PACSLAC, PAINAD, and DS-DAT. It is hoped that the present review of selected tools for assessing pain in those vulnerable population and the general recommendations given be useful for clinicians in their palliative care practice. And future studies should focus on enriching the validation of the useful tools used to observe the nonverbal patient's behavioral indicators for pain in Korean.

The Effects of High Fidelity Simulation-Based Education on Clinical Competence and Confidence in Nursing Students: A Systematic Review (고충실도 시뮬레이션 기반 교육이 간호학생의 임상수행능력과 간호수행 자신감에 미치는 효과: 체계적 문헌 고찰)

  • Lee, Chong-Mi;So, Hyang-Sook;Kim, Younkyoung;Kim, Jeong-Ee;An, Minjeong
    • The Journal of the Korea Contents Association
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    • v.14 no.10
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    • pp.850-861
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    • 2014
  • The purpose of this review was to evaluate the effects of simulation-based education on clinical competence and confidence in nursing students and summarize the available evidence on the simulation-based intervention. A systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA Statement was conducted. Studies published between 2005 and 2014 were reviewed using the following databases: RISS, KISS, and Google Scholar. The keywords used were nursing and either simulation or simulator. Selected studies were assessed for methodological quality using Quality Assessment Tool for Quantitative Studies. Seventeen studies were identified, including a total of 1,912 nursing students. All the 16 studies found simulation as a valid strategy on clinical competence and confidence in nursing education. This review provides updated evidence for simulation-based learning in nursing education. Further studies are needed to increase generalizability using randomized controlled trials, enough sample size, and longitudinal study design. In addition, valid measurements are needed to assess the main outcomes.

A Study on the Concept of Meaningful Activity for the Elderly and the Evaluation of Participation: Research Trends and Prospect for Utilization (노인의 의미 있는 활동의 개념과 참여 평가에 관한 고찰: 연구경향과 활용 전망)

  • Park, Da Sol;Park, Hae Yean
    • Therapeutic Science for Rehabilitation
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    • v.9 no.4
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    • pp.83-93
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    • 2020
  • Objective : This study was designed to analyze the concepts of current use and meaningful activity in the elderly and provide basic data on establishing concept of participation in meaningful activity and clinical applications. Methods : Using RISS, Google Scholar, Published and DBpia databases, the literature published in the journal was collected from January 2010 to July 2019. The main search term used was "meaningful activity" and 10 of the 182 papers were finally selected for analysis. Based on the qualitative level assessment study by Arbesman, Scheer and Lieberman (2008), the selected paper were classified as Level I to Level V. Results : Five out of 10 studies were published within the last 5 years, indicating that meaningful activity-related studies have been conducted recently. Through prior studies, the concept of meaningful activities was summarized as those that enable individuals to realize their values, achieve their goals and experience positive emotions in their daily lives. Conclusion : The concepts and direction of assessment tools derived from this study will be the basis for the study of 'meaningful activity participation' as a solution to the aging society's elderly problems in the future.

Harmony search algorithm and its application to optimization problems in civil and water resources engineering (화음탐색법과 토목 및 수자원공학 최적화문제에의 적용)

  • Kim, Joong Hoon
    • Journal of Korea Water Resources Association
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    • v.51 no.4
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    • pp.281-291
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    • 2018
  • Harmony search algorithm (HSA), developed by Hydrosystem lab. in Korea University in 2001, was a new meta-heuristic optimization algorithm inspired by the iterative improvision process of Jazz music players where the best harmony is eventually produced. HSA is now one of the most well-known meta-heuristic algorithms (as proven by its cited number of the first published paper more than 3,600 times as of January 11th 2018 based on Google Scholar citation) and has been applied to diverse research domains such as not only water resources and civil engineering but also in medical science, business, and humanities. This paper is a review article written with the wish for wider application of HSA and other optimization algorithms, especially in the domain of water resources engineering. Therefore, this paper first briefly introduces the mechanism and operators of HSA and then reviews its application area and citation frequency per research domain. In addition, recent globalization of HSA will be investigated and summarized by checking the current status of related international conferences and on-going research projects. After reviewing previous domestic papers with optimization algorithms specifically published in the water resources domain, this paper is finalized by delivering some suggestions to encourage the application of optimization algorithms including HSA.