• Title/Summary/Keyword: Good science class

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Solar Activity as a Driver of Space Weather II. Extreme Activity: October-November 2003

  • Jo, Gyeong-Seok;Mun, Yong-Jae;Kim, Rok-Sun;Hwang, Yu-Ra;Kim, Hae-Dong;Jeong, Jong-Gyun;Im, Mu-Taek;Park, Yeong-Deuk
    • Bulletin of the Korean Space Science Society
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    • 2004.04a
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    • pp.38-38
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    • 2004
  • In this talk, we present a good example of extreme solar and geomagnetic activities from October to November, 2003. These activities are characterized by very large sunspot groups, X-class solar flares, strong particle events, and huge geomagnetic storms. We discuss ground-based and space-based data in terms of space weather scales. We applied the CME propagation models to these events in order to predict the arrivals of heliospheric disturbances. (omitted)

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Design, Synthesis and in-vitro Screening of New 1H-Pyrazole and 1,2-Isoxazole Derivatives as Potential Inhibitors for ROS and MAPK14 Kinases

  • Al-Sanea, Mohammad M.;El-Deeb, Ibrahim M.;Lee, So Ha
    • Bulletin of the Korean Chemical Society
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    • v.34 no.2
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    • pp.437-442
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    • 2013
  • A new series of 4-(2-(substituted)pyridin-4-yl)-3-(3-methoxy-5-methylphenyl)-1H-pyrazoles (4a-f) and their 1,2-isoxazole analogues (5a-f) has been rationally designed, synthesized and screened against both ROS and MAPK14 kinases. Compounds 4b, 4c and 4e showed moderate inhibitions against both ROS and MAPK14 kinases. Compound 4e has showed the strongest inhibitions with IC50 values of 1.25 ${\mu}M$ and 3.00 ${\mu}M$ against ROS and MAPK14 kinases, respectively. A brief structure-activity relationship study and a molecular modeling study were made revealing a group of essential structural features for good kinase inhibitory activity within this new class of kinase inhibitors.

Framework for End-to-End Optimal Traffic Control Law Based on Overlay Mesh

  • Liu, Chunyu;Xu, Ke
    • Journal of Communications and Networks
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    • v.9 no.4
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    • pp.428-437
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    • 2007
  • Along with the development of network, more and more functions and services are required by users, while traditional network fails to support all of them. Although overlay is a good solution to some demands, using them in an efficient, scalable way is still a problem. This paper puts forward a framework on how to construct an efficient, scalable overlay mesh in real network. Main differences between other overlays and ours are that our overlay mesh processes some nice features including class-of-service(CoS) and traffic engineering(TE). It embeds the end-to-end optimal traffic control law which can distribute traffic in an optimal way. Then, an example is given for better understanding the framework. Particularly, besides good scalability, and failure recovery, it possesses other characteristics such as routing simplicity, self-organization, etc. In such an overlay mesh, an applicable source routing scheme called hierarchical source routing is used to transmit data packet based on UDP protocol. Finally, a guideline derived from a number of simulations is proposed on how to set various parameters in this overlay mesh, which makes the overlay more efficient.

The test-retest reliability of gait kinematic data measured using a portable gait analysis system in healthy adults

  • An, Jung-Ae;Byun, Kyung-Seok;Lee, Byounghee
    • Journal of Korean Physical Therapy Science
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    • v.27 no.3
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    • pp.25-34
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    • 2020
  • Background: Gait analysis is an important measurement for health professionals to assess gait patterns related to functional limitations due to neurological or orthopedic conditions. The purpose of this study was to investigate the reliability of the newly developed portable gait analysis system (PGAS). Design: Cross-sectional design. Test-retest study. Methods: The PGAS study was based on a wearable sensor, and measurement of gait kinematic parameters, such as gait velocity, cadence, step length and stride length, and joint angle (hip, knee, and ankle) in stance and swing phases. The results were compared with a motion capture system (MCS). Twenty healthy individuals were applied to the MCS and PGAS simultaneously during gait performance. Results: The test-retest reliability of the PGAS showed good repeatability in gait parameters with mean intra-class correlation coefficients (ICCs) ranging from 0.840 to 0.992, and joint angles in stance and swing phase from 0.907 to 0.988. The acceptable test-retest ICC was observed for the gait parameters (0.809 to 0.961), and joint angles (0.800 to 0.977). Conclusion: The results of this study indicated that the developed PGAS showed good grades of repeatability for gait kinematic data along with acceptable ICCs compared with the results from the MCS. The gait kinematic parameters in healthy subjects can be used as standard values for adopting this PGAS.

How Product Innovation and Motivation Drive Purchase Decision as Consumer Buying Behavior

  • RAYI, Gusti;ARAS, Muhammad
    • Journal of Distribution Science
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    • v.19 no.1
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    • pp.49-60
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    • 2021
  • Purpose: A good physical appearance greatly affects a person's self-confidence, especially when the media constantly depicts that beautiful men and women are those with perfect bodies, which later forms the perception that being fat or too thin is not attractive. That is in line with the increasing knowledge and the need for nutritious foods and drinks for diets. Therefore, this study aims to see whether there is a relationship between the Weight Rejuvenation Program Everyday product innovation towards millennial purchase decision and the motivation of having an ideal body as a moderating effect. Research design, data, and methodology: Distributed online Google form questionnaires to 96 audiences who commented on "Mute" web series. The respondents consisted of 63 women and 33 men from the millennial generation who lived in Greater Jakarta and were classified as the middle to upper economic class. After all of the data were collected, they were processed using Structural Equation Modeling Partial Least Squares. Results: Product innovation had a significant influence on the purchasing decisions of the millennial consumer, but motivation did not have the moderating function in the relationships between product innovation and purchase decision. Conclusions: The main factor for product innovation that can be accepted by millennials is the product quality that remains good.

The Reliability and Validity of a Portable Hand-held Spirometer for the Measurement of Various Lung Functions in Healthy Adults

  • Merve Nur Uygun;Jun-Min Ann;Byeong-Hyeon Woo;Hyeon-Myeong Park;Ha-Im Kim;Dae-Sung Park;In-Beom Jeong
    • Physical Therapy Rehabilitation Science
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    • v.13 no.2
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    • pp.179-186
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    • 2024
  • Objective: This study aims to assess the reliability and validity of the new hand-held spirometer as a potential substitute for traditional pulmonary function testing (PFT) devices. Design: Cross-sectional study. Methods: In this study, thirty healthy adults underwent spirometry using both the new hand-held spirometer and the MIR spirometer, which is a standard PFT device. Parameters including peak expiratory flow (PEF), forced expiratory volume in one second (FEV1), and forced vital capacity (FVC) were measured and analyzed for validity and reliability. Inter-rater reliability and validity were evaluated through 95% limits of agreement (LOA) and intraclass correlation coefficients (ICC). Statistical analyses, including the Bland-Altman plots and the ICC, were utilized to assess agreement between the two devices. Results: The new hand-held spirometer exhibited a good agreement with intra-class coefficient (ICC [2,1]) ranging 0.762 to 0.956 and 95% LOA of -1.94 to 1.80 when compared with MIR. The test-retest reliability of the hand-held spirometer analyzed using - ICC [2,1] demonstrated a good level of consistency (ICC [2,1] =0.849-0.934). Conclusions: In conclusion, the study aimed to assess the potential of the new hand-held spirometer as a viable alternative to traditional PFT devices, with a specific focus on its reliability and validity in spirometric measurements. The new hand-held spirometer exhibited good test-retest reliability across all measured variables, suggesting its potential as a valid and reliable tool for simultaneous PFT measurements.

A Qualitative Study of Running Science-Related Extra Curricular Activity (과학관련 계발활동 부서 운영에 대한 질적연구)

  • 채동현;김은영
    • Journal of Korean Elementary Science Education
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    • v.21 no.1
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    • pp.25-41
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    • 2002
  • The Korean National curriculum is divided into the curriculum, discretion, and extra curriculum activity. Extra curriculum among them consists of fie grounds, that is, a self-governing, adjusting, developing, service and exercise activity. The content of developing activity among them includes academic literary arts, in that the developing activity related to science. The developing activity connected with science can be a good chance which students can have deepened learning besides a regular course. In addition, effective management in science class can play an important role to cultivate scientific sense and to raise scientific talent. The study finds out how the management connected with science-related extra-curricula activity in science is actually going on. The study carries out a questionnaire with 40 teachers and interviews 5 teachers as well who are in charge of science-related extra-curricula activity connected with science. As a result, on the side of students, ① systematic introduction course in science is not given to them, ② the course is operating without considering students interests and levels, so it causes the problems of developing their potential ability and extension. On the side of teachers, ① they organize the science department based on school's situation and policy. ② they disregard teachers' roles and interests. ③ the science department's program is operating improvisedly rather than systematically, ④ the evaluation is done formally is found out. I have come to know that to manage a desirable science-related extra-curricula activity connected with science needs to have sufficient, detailed materials and experts from outside.

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Binding Mode Prediction of 5-Hydroxytryptamine 2C Receptor Ligands by Homology Modeling and Molecular Docking Analysis

  • Ahmed, Asif;Nagarajan, Shanthi;Doddareddy, Munikumar Reddy;Cho, Yong-Seo;Pae, Ae-Nim
    • Bulletin of the Korean Chemical Society
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    • v.32 no.6
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    • pp.2008-2014
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    • 2011
  • Serotonin or 5-hydroxytryptamine subtype 2C ($5-HT_{2C}$) receptor belongs to class A amine subfamily of G-protein-coupled receptor (GPCR) super family and its ligands has therapeutic promise as anti-depressant and -obesity agents. So far, bovine rhodopsin from class A opsin subfamily was the mostly used X-ray crystal template to model this receptor. Here, we explained homology model using beta 2 adrenergic receptor (${\beta}$2AR), the model was energetically minimized and validated by flexible ligand docking with known agonists and antagonists. In the active site Asp134, Ser138 of transmembrane 3 (TM3), Arg195 of extracellular loop 2 (ECL2) and Tyr358 of TM7 were found as important residues to interact with agonists. In addition to these, V208 of ECL2 and N351 of TM7 was found to interact with antagonists. Several conserved residues including Trp324, Phe327 and Phe328 were also found to contribute hydrophobic interaction. The predicted ligand binding mode is in good agreement with published mutagenesis and homology model data. This new template derived homology model can be useful for further virtual screening based lead identification.

A clinical case of hybrid telescopic double crown using friction pin with an isolated few remaining teeth (고립된 소수 잔존치 환자에서 프릭션핀을 이용한 하이브리드 텔레스코픽 이중관 국소의치의 임상증례)

  • Sohn, Sang-Hyuk;Cho, Jin-Hyun;Cho, Sung-Am
    • Journal of Dental Rehabilitation and Applied Science
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    • v.32 no.1
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    • pp.80-86
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    • 2016
  • A few authors have reported good clinical results using double crown removable partial denture (RPD) with a few remaining teeth. Hybrid telescopic double crown is a good indication for a patient with poor periodontal condition and/or few remaining teeth after extraction, especially located in cross-arch position. In this case, there was a poor periodontal condition with teeth mobility. Several teeth with poor prognosis were extracted. Remaining anterior teeth was restored with fixed prostheses and edentulism was restored with Kennedy class I removable partial denture in maxilla. In mandible, it was hard to restore with clasp removable partial prostheses because of bilaterally isolated remaining teeth so that hybrid double crown removable partial denture with friction pin was suitable for this case. The objective of this report is to discuss the characteristics and the utility of hybrid double crown prostheses using a few remaining teeth in mandible.

THE STUDY OF THE WEDDING BUSINESS IN THE DEPARTMENT OF CULINARY DEPT. OF JUNIOR COLLEGE. (호텔조리과의 부대사업 운영에 관한 연구 - 결혼식장 운영을 중심으로 -)

  • 정진구
    • Culinary science and hospitality research
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    • v.3
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    • pp.271-289
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    • 1997
  • The purpose of this study is to investigate previous data and possibility of the new culture building, insuring substantiality of the education in junior college, increasing of practical carrier, acquiring the money for practical class, and the direction of demand for education in a high level of industrial society. There's two parts to consist of investigation and the model case in wedding business in Junior college. The research groups in one part consist of 277 students in Junior college. The result were as follows: 1) The students would like to get the wedding business in new culture building. (72%) 2) The student shave got a idea to recommend to use the wedding facilities for their for their relative sand friends. (51%) 3) The trend of selecting in wedding facilities is outside than inside of facilities. (75%) 4) They would like to have the buffet service after wedding celemony, not a la carte for choose the meal. The above research data suggest that if the wedding facility's management would be accept, we could have expectation about development of junior college, emphasis of practical education and good wedding culture in this areas. For the most of student, they has a righ hand to manage the wedding facility in their college. First, the culinary students could have an experience of service practies to the customer in wedding celemony, as the result of training will be great. Second, the college could show their vision and hope to customer to interest it. Third, it can be supplied the right wedding culture and the wedding facilities which is low price and good circumstance for wedding. Fourth, it's very resonable to use the culture facilities during no class, Saturday and Sunday. Fifth, income from business can be used only a scholarship and a community development. Sixth, it can be induced the self-participication and motivation to take up a positive attitude for their life.

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