• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 가을 학술발표논문집 Vol.34 No.2 (A)
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• pp.187-188
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• 2007

• 대한화학회지
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• 제36권4호
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• pp.610-612
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• 1992

• 동의생리병리학회지
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• 제16권5호
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• pp.1016-1019
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• 2002

To examine the cytotoxic effect of glucose oxidase(GO) in cultured mouse cerebral neurons, cytotoxicity was measured by MTT assay after cultured nerve cells were incubated for 3 hours in the media containing 1 ～ 60mU/ml concentrations of GO. In addition, the neuroprotective effect of Ramulus et uncus uncariae(REUU) was determined by MTT assay in these cultrures. Cell viability was remarkably decreased in a dose- and time-dependent manner after cultured mouse cerebral neurons were exposed to 30mU/ml GO for 3 hours. In the neuroprotective effect of REUU on GO-induced toxicity, REUU blocked the GO-mediated neurotoxicity in these cultures. From above the results, it suggests that GO is toxic in cultured mouse cerebral neurons and selective herb extract such as REUU is effective in prevetion of the neurotoxicity induced by GO.

• 한국식품영양학회지
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• 제28권6호
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• pp.1026-1032
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• 2015

본 연구는 ${\beta}$-galactosidase와 효모 발효에 의해 고순도 갈락토올리도당(HP-GOS)의 제조를 위한 효율적인 방법을 찾고자 수행하였다. 6종의 상업용 ${\beta}$-galactosidase를 이용해 효소반응 전후의 구성당을 각각 비교한 결과, Lactozym 3000L을 이용하여 제조한 GOS에서 효소반응을 통해 생성된 total GOS의 양이 가장 높은 것으로 나타났다. 생성된 GOS의 농도는 초기 lactose로부터 51%의 전환율을 나타냈다. 또한 GOS의 수율은 효모(Saccharomyces cerevisiae)의 발효에 의해 더욱 높아졌는데, 효모를 8% 첨가하여 36시간 발효 후 생성된 GOS의 농도는 71%까지 도달했음을 확인하였다. HPLC를 이용한 구성당 분석 결과, S. cerevisiae에 의한 발효를 통해 제조한 HP-GOS에는 발효 전에 존재했던 glucose의 함량이 급감되었을 뿐 아니라, 4'/6'-galactosyllactose와 total GOS의 양은 유의적으로 증가되었다. HP-GOS는 상업용 GOS보다 Lactobacillus 속(L. acidophilus and L. casei) 및 Bifidobacterium 속(B. longum and B. bifidum)의 성장을 촉진시키는 것으로 확인되었다. 이러한 결과를 종합해 볼 때, 효소 처리 및 효모 발효를 통해 고순도의 GOS가 제조되었으며, 제조된 HP-GOS는 상업용 GOS에 비해 장내 유용균으로 알려진 Bifidobacterium 속과 Lactobacillus 속의 생육을 증가시킴으로써 인간의 장내 건강에도 유익한 영향을 미칠 것으로 사료된다.

• 천문학회지
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• 제12권1호
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• pp.35-40
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• 1979

Astronomical records in the days of King Jeongjo of Yi dynasty, 1777-1800, are examined for solar and lunar eclipses, meteors and comets. The books used for this investigation are Sung Jeong Won Il Gi, which are the original daily records written in the court. The records found in these Sung Jeong Won Il Gi are tabulated according to the four astronomical phenomena above, and they were cross checked with the records in the book, Jung Bo Mun Heon Bi Go. Although Jung Bo Mun Heon Bi Go has most frequently been used as the original records to those who work for the ancient Korean records, the inaccuracy and the deficiency are found.

• 한국전자거래학회:학술대회논문집
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• 한국전자거래학회 2003년도 종합학술대회 논문집
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• pp.197-203
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• 2003

The purpose of the study is to develop an integrated knowledge structuring system for the domain of engineering, in which ontology-based literature mining, knowledge acquisition, knowledge integration, and knowledge retrieval are combined using XML-based tag information and ontology management. The system supports combining different types of databases (papers and patents, technologies and innovations) and retrieving different types of knowledge simultaneously. The main objective of the system is to facilitate knowledge acquisition and knowledge retrieval from documents through an ontology-based dynamic similarity calculation and a visualization of automatically structured knowledge. Through experimentations we conducted using 100,000 words economic documents reported in the "Go！ Japan" project for analyzing Japanese industrial situation, and 100,000 words molecular biology Papers, we show the system is Practical enough for accelerating knowledge acquisition and knowledge discovery from the information sea.

• 전기학회논문지
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• 제61권2호
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• pp.312-320
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• 2012

In this study, we introduce a new design methodology of a granular-oriented self-organizing polynomial neural networks (GoSOPNNs) that is based on multi-layer perceptron with Context-based Polynomial Neurons (CPNs) or Polynomial Neurons (PNs). In contrast to the typical architectures encountered in polynomial neural networks (PNN), our main objective is to develop a methodological design strategy of GoSOPNNs as follows : (a) The 1st layer of the proposed network consists of Context-based Polynomial Neuron (CPN). In here, CPN is fully reflective of the structure encountered in numeric data which are granulated with the aid of Context-based Fuzzy C-Means (C-FCM) clustering method. The context-based clustering supporting the design of information granules is completed in the space of the input data while the build of the clusters is guided by a collection of some predefined fuzzy sets (so-called contexts) defined in the output space. (b) The proposed design procedure being applied at each layer of GoSOPNN leads to the selection of preferred nodes of the network (CPNs or PNs) whose local characteristics (such as the number of contexts, the number of clusters, a collection of the specific subset of input variables, and the order of the polynomial) can be easily adjusted. These options contribute to the flexibility as well as simplicity and compactness of the resulting architecture of the network. For the evaluation of performance of the proposed GoSOPNN network, we describe a detailed characteristic of the proposed model using a well-known learning machine data(Automobile Miles Per Gallon Data, Boston Housing Data, Medical Image System Data).

• 혜화의학회지
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• 제21권2호
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• pp.139-147
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• 2013

Objectives: The aim of this study was to investigate the preventive effects of Sambok-go for upper respiratory tract infection. Methods: Sambok-go was performed to outpatients which had visited Daejeon university oriental medicine hospital. The number of participants who received Sambok-go at least once were 85, 21 patients did not receive Sambok-go three times were excluded first. Participants who received treatment three times were 64 patients. After the 2011 winter, 2012.05 we follow-up by telephone, except eight, 56 patients were analyzed. Sambok-go is composed of 8 kinds of medicinal herbs. Each Sambok-go weighs about 1.1g and attatchment surface diameter is about 1.5 cm. Sambok-go was attached to both side of 폐유(肺兪)(BL13), 심유(心兪)(BL15), 폐유(膈兪)(BL17), patients under the age of 15 were attached for an hour, patients over 15 years age were attatched for 3 hours. Results: Among the finally analyzed 56 participants, we compared the number of flu outbreak during winter before and after treatment. Before treatment measured $6.14{\pm}6.57$, after treatment measured $1.57{\pm}1.14$. In conclusion, the number of flu outbreak was significantly decreased(p<0.001). To investigate the effect of worsening factors on the pre-existing upper respiratory diseases, we checked whether the patients had pre-existing upper respiratory diseases. The patients who already had old upper respiratory diseases were 34. The increase in the frequency of deterioration in 5 patients, 4 patients no change, decreased in 24 cases, one patient was unresponsive. After evaluating the satisfaction of The patients who were treated with the Sambok-Go, the 29 cases were very satisfied, the 23 were satisfied, None of the paitents showed dissatisfaction or bad dissatisfaction. Conclusion: Sambok-go seems to be effective in the prevention of URI. Further studies are recommended to confirm this effect.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2018년도 춘계학술논문요약집
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• pp.379-380
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• 2018

• 한국화재소방학회논문지
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• 제13권1호
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• pp.31-36
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• 1999

1996년 4월 23일 강원도 고성군에서 발생한 산불에 대한 현장조사와 주요수목인 굴참나무와 소나무에 대한 열량에 대한 실험을 하였다. 산불의 확산에 영향을 주는 주된 요인은 크게 기상, 연료, 지형 3가지로 구분할 수 있는 데 기상 조건에서는 산불위험경보 수준이었고, 연료 조건에서는 높은 열량값을 가지고 이쓴 소나무 순림이 전체 산림의 63%를 차지하고 있었다. 산림의 지형에서는 지형의 변화와 기복이 크며 단순상향사면형의 지형이 어우러진 골짜기 형태로 급경사지가 대부분이었다. 주요 수목인 소나무와 굴참나무의 열량 실험에 대한 분석 결과는 소나무의 경우 부위별 전체 열량값이 13.43kcal/g, 굴참나무는 9.46kcal/g로 나타났다. 열분해에 의한 질량손실의 경우 소나무가 굴참나무보다 약 35.71~10.05% 더 높은 질량 손실률을 나타냈다. 따라서 소나무가 굴참나무보다 열에 대한 저항성이 낮다고 볼 수 있다.