• Archives of Plastic Surgery
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• 제36권4호
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• pp.493-496
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• 2009

Purpose: Glomus tumors are neoplasms that are composed of modified smooth muscle cells of the glomus body and multiple glomus tumor comprises 10% of all glomus tumors. We report a case of disseminated multiple glomus tumors. Methods: A 14 - year - old boy presented with multiple subcutaneous purple nodules on the right cheek, back, right arm, right hand dorsum, right fourth finger, and left ankle. Nodules on the back and right fourth finger were completely excised under local anesthesia and histopathologic examination was followed. Results: Histopathologic findings showed numerous dilated, cavernous - like, thin - walled, vascular spaces surrounded by one or a few layers of glomus cells. On immunohistochemical examination, glomus cells stain for smooth muscle actin, and endothelial cells stain for CD31. Those revealed multiple glomangiomas. Conclusion: A review of Korean literature revealed only one reported cases of disseminated multiple glomus tumors, so this is the second case to be reported in the Korean literature. In case of multiple soft tissue tumors, thorough physical examination and preoperative evaluation is needed.

• Journal of Chest Surgery
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• 제26권3호
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• pp.241-244
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• 1993

The glomus tumor is a distinctive benign neoplasm, the cells of which resemble the modified smooth muscle cells of the normal glomus body. This tumor occurs most frequently in the extremities but may find elsewhere in the body. Only one case of mediastinal glomus tumor has been reported in the world. Recently we experienced a case of mediastinal glomus tumor managed with surgical removal and followed up without any significant complications for 17 months.

• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.185-187
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• 2010

A 52-year-old female patient presented with an 8-year history of progressively intense pain, cold sensitivity, and severe tenderness to palpation of the ulnar side of the tip of her right little finger. Subsequent diagnostic evaluation with ultrasonographic imaging revealed the presence of a glomus tumor in the tender area. Glomus tumors are benign, occurring in the vascular hamartomatous tubercles of the glomus body, which is a myoarterial apparatus typically found in the reticular dermis of the skin. Distal glomus tumors are relatively uncommon, and account for approximately 1% of all hand tumors. Most of them are located in the subungual area because of its high concentration of glomus bodies. We report a case of a glomus tumor with a typical triad of symptoms, yet with a rare location : on the pulp of the ulnar aspect of the distal phalanx of the right little finger.

• Archives of Plastic Surgery
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• 제40권4호
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• pp.392-396
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• 2013

Background The typical clinical symptoms of glomus tumors are pain, tenderness, and sensitivity to temperature change, and the presence of these clinical findings is helpful in diagnosis. However, the tumors often pose diagnostic difficulty because of variations in presentation and the nonspecific symptoms of glomus tumors. To the best of our knowledge, few studies have reported on the usefulness of magnetic resonance imaging (MRI) in diagnosing glomus tumors in patients with unspecific symptoms. Methods The inclusion criteria of this study were: having undergone surgery for subungual glomus tumor of the hand, histopathologic confirmation of glomus tumor, and having undergone preoperative MRI. Twenty-one patients were enrolled. The characteristics of the tumors and the presenting symptoms including pain, tenderness, and sensitivity to temperature change were retrospectively reviewed. Results Five out of 21 patients (23%) did not show the typical glomus tumor symptom triad because they did not complain of pain provoked by coldness. Nevertheless, preoperative MRI showed well-defined small soft-tissue lesions on T1- and T2-weighted images, which are typical findings of glomus tumors. The tumors were completely resected and confirmed as glomus tumor histopathologically. Conclusions Early occult lesions of glomus tumor in the hand may not be revealed by physical examination because of their barely detectable symptoms. Moreover, subungual lesions may be particularly difficult to evaluate on physical examination. Our cases showed that MRI offers excellent diagnostic information in clinically undiagnosed or misdiagnosed patients. Preoperative MRI can accurately define the character and extent of glomus tumor, even though it is impalpable and invisible.

• Archives of Plastic Surgery
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• 제38권3호
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• pp.319-322
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• 2011

Purpose: Glomus tumor is a benign neoplasm of the normal glomus body, occurring as painful subcutaneous nodules, frequently located in the subungual area. There are few cases of facial glomus tumor reported and we report a case of glomus tumor developing on the columella of nose. Methods: A 68-year-old female presented with a mass of the columella grown for 2 years. The nodule was 0.6 cm in diameter, red-colored without any symptoms such as pain, tenderness and cold hypersensitivity. The pathologic result after punch biopsy was hemangiopericytoma. Excision with local anesthesia was executed. Results: The postoperative recovery of the patient was uneventful, Histopathological examination indicated a glomus tumor. Immunostaining revealed positivity for vimentin, actin, and negativity for desmin, CD-34. After 8 months follow up, there is neither complication nor evidence of local recurrence on clinical examination. Conclusion: To accomplish an accurate diagnosis of glomus tumor, the histopathological examination is essential together with immunochemical studies. The differential diagnosis include hemangioma, lipoma, epidermal inclusion cyst, dermoid cyst and arteriovenous malformation in this region. We report a case of glomus tumor on the face with uncommon clinical features.

• The Korean Journal of Pain
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• 제26권3호
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• pp.295-298
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• 2013

Glomus tumors are benign tumors that account for 1% to 5% of all soft tissue tumors of the hand and are characterized by a triad of sensitivity to cold, localized tenderness and severe paroxysmal pain. Paroxysmal pain is a symptom common not only in glomus tumors but also in CRPS, and the hand is one of the commonly affected sites in patients with both glomus tumors and CRPS. Therefore, it is not easy to clinically diagnose glomus tumors superimposed on already affected region of CRPS patients. We report a case of glomus tumor concomitantly originating with CRPS at the hand.

• 한국균학회지
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• 제40권1호
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• pp.1-6
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• 2012

본 연구에서는 인삼(Panax ginseng C. A. Mey.) 재배 토양에서 수지상균근균(AMF)의 포자를 분리하여 동정하고 재배기간 별 AMF 다양성을 확인하였다. 충남 금산지역의 재배 기간 1~5년의 인삼 재배지에서 토양을 채집하였다. 인삼 재배지에 분포하는 AMF의 포자를 분리하여 형태 및 분자생물학적 동정을 한 결과, Acaulospora longula, Archaeospora trappei, Glomus caledonium, Glomus etunicatum, Glomus intraradices, Glomus mosseae, Glomus sp., Paraglomus occultum, Paraglomus brasilianum Scutellospora heterogama 등 총 5속 10종이 동정되었다. 연구 결과 재배기간이 오래 될수록 토양 내에 분포하는 수지상균근균의 종 다양성지수와 균등도는 유의미한 차이를 보이며 감소하였다. 그러나 A. trappei 는 재배 기간이 오래될수록 상대수도가 증가하였다.

• 대한족부족관절학회지
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• 제11권1호
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• pp.100-103
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• 2007

Glomus tumors are uncommon soft tissue tumors which usually found in a subungual lesion of hand, producing pain. This uncommon tumors have been reported in other locations, including nasal cavity, stomach, mediastinum, heart, lung, and vagina etc. Especially, it was a very rare case found in an extradigital lesion of foot. Glomus tumors should not be ruled out for an extradigital mass lesion of foot and also any other locations. Although glomus tumors are generally considered a benign lesion, it should be considered that glomus tumors have also reported as a malignant type tumor, even the diagnosis based on histologic features not clinical one.

• 한국균학회지
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• 제17권1호
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• pp.14-20
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• 1989

전주시 완산공원(Cryptomeria japonica dominant forest) 및 두 해안지역(경북 신창리, Digitaria sanguinalis dominant; 아산군 삽교천 Pragmited communis dominant)에서 채취한 토양시료로부터 내생균근 균을 관찰하였다. Endogonales에 속하는 3개 속(Acaulospora, Glomus, Scutellospora)에 6개 종이 동정되었다 ; Aculospora bireticulata, Glomus clarum, Glomus intraradices, Glomus occultum, Scutellospora aurigloba, Scutellospora gilmorei.

• Applied Microscopy
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• 제24권1호
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• pp.11-27
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• 1994

The morphological development of the carotid body was studied by electron microscope in human fetuses from 40mm to 260mm crown rump length (10-30 weeks of gestational age). At 40mm fetus, the carotid body was composed of cluster of primitive glomus cells, primitive supporting cells, unmyelinated nerve fibers, and blood capillaries. In connective tissue between internal and external carotid arteries adjacent to the superior cervical sympathetic ganglion, two types of glomus cells through all prenatal period were found. Dark cells contained a dense cytoplasm with conspicuous large dense-cored granules, whereas light cells had a less dense cytoplasm with dense-cored granules. The light cells contained dense-cored granules that were smaller and less abundant than those in the dark cells. The primitive supporting cells appeared star-shaped with attenuated cytoplasmic extensions intervening between the adjacent glomus cells. Synaptic contact between the axon terminals and soma of the glomus cells were first observed at 40mm fetus. In 80-100mm fetus, the carotid body contained tightly packed collection of glomus cells and supporting cells which surrounded the abundant thin-walled blood vessels. Intercellular junctions between the glomus cells and adjacent cells were commonly seen. Nerve endings on the glomus cells have the form of small boutons and the other from of large calyces. During the second half of the fetal period, the glomus cells were completely enveloped by supporting cells and nerve terminals. At 260mm, the morphological features of carotid body were similar to those of human adult. The result of this study demonstrates that there are differences between the carotid body and aorticopulmonary bodies, especially with respect to their synaptic complexes, abundant blood capillaries, and two glomus cell types.