• Journal of the Korea Society of Computer and Information
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• v.24 no.10
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• pp.267-278
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• 2019

As the importance of technology in education has increased, TPACK research has been actively conducted to promote the use of technology in class. However, due to the functional limitations of technology, the pre-service teacher had difficulty in using technology in class. Therefore, in this study, we have been studying the introduction of the programming language as a technology tool of TPACK. Using design-based research as a research method, we repeatedly developed an educational program, applied to pre-service teachers, and evaluated the effectiveness of the program. In the first study, pre-service teachers had difficulties in programming learning. To solve this problem, programming-based instruction and curriculum analysis were supplemented by educational programs. In the second study, pre-service teachers felt difficulty in using programming in teaching-learning, thus improving instruction design and reflection. The third study enhanced the programming development environment search to supplement programming learning and utilization.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.4
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• pp.193-206
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• 2008

Purpose: In spite of many arguments on the result of WHI (Women's Health Initiative) study, no one can deny the necessity for researches on the alternative treatment to HRT (hormone replacement therapy). In this study, the author wanted to investigate the method of precedent acupuncture RCTs (randomized controlled trials) to make out the appropriate acupuncture study design on postmenopausal and perimenopausal hot flashes in Korea. Methods: Precedent studies were investigated using Pubmed search and key-words "acupuncture and hot flash", "acupuncture and menopause", "acupuncture and vasomotor", limited to RCT, from 2000 to 2008 April. Results: As a result. 10 studies were searched. In the hereafter studies, multi-center clinical trials which consist of population group of postmenopausal and perimenopausal women that would be pre-stratified and more than 50 patients per treatment arm seem adequate. Sham control study can make out the proper consequence because many people are get used to acupuncture in Korea. Flexible choice of acupoints addressed an individual's symptoms using standardized algorithm is recommended. Treatment consist of 4 weeks' observation, 11 acupuncture sessions during 7 weeks, follow-up of 3 months or more after treatment and hot flash score as a primary outcome measure seem appropriate. After all, higher level of description according to global standard must be obtained in the study report and publishing. Conclusion: The researchers should develope the methodology of acupuncture clinical trial on the postmenopausal and perimenopausal hot flashes.

• Journal of Pharmacopuncture
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• v.22 no.1
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• pp.49-54
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• 2019

Objective: Antibiotic resistance is a global health problem and threatens health of societies. These problems have led to a search for alternative approaches such as combination therapy. The aim of the present study was to investigate the effect of caffeine and omeprazole in combination with gentamicin or ciprofloxacin against standard and clinically resistant isolates of Staphylococcus aureus and Escherichia coli. Methods: The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of different agents against bacterial strains were determined. The interaction of non- antibiotic drugs with gentamicin and ciprofloxacin was studied in vitro using a checkerboard method and calculating fraction inhibitory concentration index (FICI). Verapamil as efflux pump inhibitor was used to evaluate the possible mechanism of bacterial resistance to antibiotics. Results: The MIC and MBC values of gentamicin against bacterial strains were in the range of $20-80{\mu}g/ml$ and $40-200{\mu}g/ml$, respectively. Caffeine and omeprazole had no intrinsic inhibitory activity against tested microorganisms. However, upon combination of caffeine with antibiotics, the synergistic effects were observed. Verapamil was able to reduce the MIC values of gentamicin (4 folds) only in some bacterial strains. Conclusion: These findings indicated that caffeine was effective in removing bacterial infection caused by S. aureus and E. coli. The relevant mechanisms of antibiotic resistance were not related to the drug efflux.

• Healthcare Informatics Research
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• v.24 no.4
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• pp.253-262
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• 2018

Objectives: We reviewed digital epidemiological studies to characterize how researchers are using digital data by topic domain, study purpose, data source, and analytic method. Methods: We reviewed research articles published within the last decade that used digital data to answer epidemiological research questions. Data were abstracted from these articles using a data collection tool that we developed. Finally, we summarized the characteristics of the digital epidemiological studies. Results: We identified six main topic domains: infectious diseases (58.7%), non-communicable diseases (29.4%), mental health and substance use (8.3%), general population behavior (4.6%), environmental, dietary, and lifestyle (4.6%), and vital status (0.9%). We identified four categories for the study purpose: description (22.9%), exploration (34.9%), explanation (27.5%), and prediction and control (14.7%). We identified eight categories for the data sources: web search query (52.3%), social media posts (31.2%), web portal posts (11.9%), webpage access logs (7.3%), images (7.3%), mobile phone network data (1.8%), global positioning system data (1.8%), and others (2.8%). Of these, 50.5% used correlation analyses, 41.3% regression analyses, 25.6% machine learning, and 19.3% descriptive analyses. Conclusions: Digital data collected for non-epidemiological purposes are being used to study health phenomena in a variety of topic domains. Digital epidemiology requires access to large datasets and advanced analytics. Ensuring open access is clearly at odds with the desire to have as little personal data as possible in these large datasets to protect privacy. Establishment of data cooperatives with restricted access may be a solution to this dilemma.

• Korean Journal of Health Psychology
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• v.16 no.3
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• pp.609-622
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• 2011

The purpose of this study is to investigate the causality between life satisfaction and domain satisfactions. For this study, data were collected from 207 respondents. They completed World Health Organization Quality of Life Assessment Instrument - Brief (WHOQOL-BREF) which is self-report questionnaire asking about life satisfaction and domain satisfactions. For data analysis, the verification procedure by autoregressive crosslagged modeling of structural equation was used. The analysis results of measures showed the causal relation between the two variables, that is, domain satisfactions acted as cause of life satisfaction. There were discussions on the issues about the analysis method of the autoregressive crosslagged modeling, the implications of the results, and the limits of the research. This study ascertained the intervention direction between life satisfaction and domain satisfactions to promote life satisfaction.

• Journal of KIISE:Software and Applications
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• v.33 no.4
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• pp.402-410
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• 2006

This paper presents a method for feature based block motion estimation that uses multi -resolution image sequences to obtain the panoramic images in the continuous ultrasound image sequences. In the conventional block motion estimation method, the centers of motion estimation blocks are set at the predetermined and equally spaced locations. This requires the large blocks to include at least one feature, which inevitably requires long estimation time. In this paper, we propose an adaptive method which locates the center of the motion estimation blocks at the feature points. This make it possible to reduce the block size while keeping the motion estimation accuracy The Harris-Stephen corner detector is used to get the feature points. The comer points tend to group together, which cause the error in the global motion estimation. In order to distribute the feature points as evenly as Possible, the image is firstly divided into regular subregions, and a strongest corner point is selected as a feature in each subregion. The ultrasound Images contain speckle patterns and noise. In order to reduce the noise artifact and reduce the computational time, the proposed method use the multi-resolution image sequences. The first algorithm estimates the motion in the smoothed low resolution image, and the estimated motion is prolongated to the next higher resolution image. By this way the size of search region can be reduced in the higher resolution image. Experiments were performed on three types of ultrasound image sequences. These were shown that the proposed method reduces both the computational time (from 77ms to 44ms) and the displaced frame difference (from 66.02 to 58.08).

• Geophysics and Geophysical Exploration
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• v.11 no.1
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• pp.15-25
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• 2008

Ocean-bottom seismometer (OBS) positions are one of the key parameters in an OBS-airgun seismic survey for crustal structure study. To improve the quality of these parameters, we have developed a new method of determining OBS positions, using airgun shot data and bathymetric data in addition to available distance measurements by acoustic transponders. The traveltimes of direct water waves emitted by airgun shots and recorded by OBSs are used as important information for determining OBS locations, in cases where there are few acoustic transponder data (<3 sites). The new method consists of two steps. A global search is performed as the first step, to find nodes of the bathymetric grid that are the closest to explaining the observed direct water-wave traveltimes from airgun shots, and acoustic ranging using a transponder system. The use of precise 2D bathymetric data is most important if the bottom topography near the OBS is extremely rough. The locations of the nodes obtained by the first step are used as initial values for the second step, to avoid falling into local convergence minima. In the second step, a non-linear inverse method is executed. If the OBS internal clock shows large drift, a secondary correction for the OBS internal clock is obtained, as well as the OBS location, as final results by this method. We discuss the error and the influence of each measurement used in the determination of OBS location.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.1A
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• pp.9-18
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• 2009

This paper introduces the application of DE (Differential Evolutionary) method for the estimation of tensile force of the externally prestressed tendon. The proposed technique, a SI (System Identification) method using the DE algorithm, can make global solution search possible as opposed to classical gradient-based optimization techniques. The numerical tests show that the proposed technique employing DE algorithm is a useful method which can detect the effective nominal diameters as well as estimate the exact tensile forces of the externally prestressed tendon with an estimation error less than 1% although there is no a priori information about the identification variables. In addition, the validity of the proposed technique is experimentally proved using a scale-down model test considering the serviceability state condition without and with the loss of the prestressed force. The test results prove that the technique is a feasible and effective method that can not only estimate the exact tensile forces and detect the effective nominal diameters but also inspect the damping properties of test model irrespective of the loss of the prestressed force. The 2% error of the estimated effective nominal diameter is due to the difference between the real tendon diameter with a wired section and the FE model diameter with a full-section. Finally, The accuracy and superiority of the proposed technique using the DE algorithm are verified through the comparative study with the existing theories.

• Journal of Intelligence and Information Systems
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• v.15 no.2
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• pp.33-48
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• 2009

Capsule endoscopy is one of the most remarkable inventions in last ten years. Causing less pain for patients, diagnosis for entire digestive system has been considered as a most convenience method over a normal endoscope. However, it is known that the diagnosis process typically requires very long inspection time for clinical experts because of considerably many duplicate images of same areas in human digestive system due to uncontrollable movement of a capsule endoscope. In this paper, we propose a method for clinical diagnosticians to get highly valuable information from capsule-endoscopy video. Our software system consists of three global maps, such as movement map, characteristic map, and brightness map, in temporal domain for entire sequence of the input video. The movement map can be used for effectively removing duplicated adjacent images. The characteristic and brightness maps provide frame content analyses that can be quickly used for segmenting regions or locating some features(such as blood) in the stream. Our experiments show the results of four patients having different health conditions. The result maps clearly capture the movements and characteristics from the image frames. Our method may help the diagnosticians quickly search the locations of lesion, bleeding, or some other interesting areas.

• Korean Journal of Remote Sensing
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• v.39 no.6_1
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• pp.1309-1320
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• 2023

The technological development and popularization of mobile devices have developed so that users can check their location anywhere and use the Internet. However, in the case of indoors, the Internet can be used smoothly, but the global positioning system (GPS) function is difficult to use. There is an increasing need to provide real-time location information in shaded areas where GPS is not received, such as department stores, museums, conference halls, schools, and tunnels, which are indoor public places. Accordingly, research on the recent indoor positioning technology based on light detection and ranging (LiDAR) equipment is increasing to build a landmark database. Focusing on the accessibility of building a landmark database, this study attempted to develop a technique for estimating the user's location by using a single image taken of a landmark based on a mobile device and the landmark database information constructed in advance. First, a landmark database was constructed. In order to estimate the user's location only with the mobile image photographing the landmark, it is essential to detect the landmark from the mobile image, and to acquire the ground coordinates of the points with fixed characteristics from the detected landmark. In the second step, by applying the bag of words (BoW) image search technology, the landmark photographed by the mobile image among the landmark database was searched up to a similar 4th place. In the third step, one of the four candidate landmarks searched through the scale invariant feature transform (SIFT) feature point extraction technique and Homography random sample consensus(RANSAC) was selected, and at this time, filtering was performed once more based on the number of matching points through threshold setting. In the fourth step, the landmark image was projected onto the mobile image through the Homography matrix between the corresponding landmark and the mobile image to detect the area of the landmark and the corner. Finally, the user's location was estimated through the location estimation technique. As a result of analyzing the performance of the technology, the landmark search performance was measured to be about 86%. As a result of comparing the location estimation result with the user's actual ground coordinate, it was confirmed that it had a horizontal location accuracy of about 0.56 m, and it was confirmed that the user's location could be estimated with a mobile image by constructing a landmark database without separate expensive equipment.