• Korean Chemical Engineering Research
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• 제48권1호
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• pp.27-32
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• 2010

후코이단을 보습제 및 기능성화장품 소재로 사용하기 위한 후코이단 특성 및 그 효과에 대해 연구하였다. 후코이단은 미역 포자엽에서 추출하였다. 화장품 소재 시험으로는 보습력 측정, 항산화(DPPH assay, radical scavenging), 안전성(MTT assay)을 실시하였다. 후코이단의 보습력은 최고의 보습제 중의 하나인 히아루론산의 보습력보다 높았고, 분자량이 감소함에 따라 보습력이 약간 증가하였다. 후코이단은 높은 안전성과 항산화력을 보였다. 후코이단의 보습력 및 항알레르기 효과를 평가하기 위해 아토피 환자 46명에게 후코이단 크림을 6주간 적용하였다. 증상 정도를 나타내는 IGA 값이 3.04에서 2.15로 감소해 39.8%의 증상개선 효과가 있었다.

• International Journal of Aeronautical and Space Sciences
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• 제10권2호
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• pp.134-139
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• 2009

Various modules are generally combined with one another in order to perform rotorcraft preliminary design and its optimization. At the stage of the preliminary design, analysis fidelity is less important than the rapid assessment of a design is. Most of the previous researchers attempted to implement sophisticated applications in order to increase the fidelity of analysis, but the present paper focuses on a rapid assessment while keeping the similar level of fidelity. Each small-sized module will be controlled by an externally-operated global optimization module. Results from each module are automatically handled from one discipline to another which reduces the amount of computational effort and time greatly when compared with manual execution. Automatically handled process decreases computational cycle and time by factor of approximately two. Previous researchers and the rotorcraft industries developed their own integrated analysis for rotorcraft design task, such as HESCOMP, VASCOMP, and RWSIZE. When a specific mission profile is given to these programs, those will estimate the aircraft size, performance, rotor performance, component weight, and other aspects. Such results can become good sources for the supplemental analysis in terms of stability, handling qualities, and cost. If the results do not satisfy the stability criteria or other constraints, additional sizing processes may be used to re-evaluate rotorcraft size based on the result from stability analysis. Trade-off study can be conducted by connecting disciplines, and it is an important advantage in a preliminary design study. In this paper among the existing rotorcraft design programs, an adequate program is selected for a baseline of the design framework, and modularization strategy will be applied and further improvements for each module be pursued.

• 대한영양사협회학술지
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• 제20권4호
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• pp.285-295
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• 2014

The purpose of this study was to examine changes in nutrient intake in patients at nutritional risk. We included 106 malnourished patients who were admitted to Severance Hospital from March to September 2014. The average age was $59.0{\pm}11.6$ years old and 59 patients were male (59.7%). The majority of diagnosis was cancer (94.3%). We evaluated patients' nutritional status by scored patient-generated subjective global assessment (PG-SGA), anthropometric measurement (height, weight, body composition by Bioelectrical impedance analysis), hand grip strength, biochemical and dietary assessment. The patients' daily intakes of energy and protein ($1,019.5{\pm}706.4kcal$, $40.4{\pm}27.7g$) during hospitalization were significantly lower than their usual intakes ($1,382.0{\pm}499.8kcal$, $54.4{\pm}25.1g$, P<0.001). Serum levels of albumin, cholesterol, and total lymphocytes were significantly reduced during hospital stay. The negatively influencing factors for reduced dietary intake were anorexia (42.5%), abdominal distention (14.2%), pain (13.2%), and others. The results of this study could be used to establish baseline data for developing new strategies for nutritional intervention in malnourished patients.

• 전자공학회논문지
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• 제52권10호
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• pp.97-107
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• 2015

디지털 엑스레이 기기로부터 처음 획득된 엑스레이 영상은 데이터 범위가 일반 영상에 비해 넓고 밝기 레벨이 고르지 못하다. 특히 흉부 엑스레이 영상의 경우 다양한 이유로 촬영하기 때문에 갈비뼈와 혈관, 척추 뼈 등 특성이 다른 모든 부위들을 자연스럽게 개선할 필요가 있다. 이러한 엑스레이 영상의 경우 일반 영상과 특성이 다르기 때문에 기존의 화질 개선 알고리즘으로는 진단에 적합한 화질을 얻을 수 없다. 따라서 본 논문은 특정 밝기에 밀집된 정보들의 히스토그램 범위를 확장시키고, 주파수 대역 별 가중치 조절을 통한 선명도 개선 및 고주파 성분의 특성을 이용한 영상 융합 기법을 통해 최종적으로 영상의 대비를 적절하게 개선하는 흉부 엑스레이 영상용 화질 개선 방법을 제안한다. 또한 기존의 기법들과 비교하여 흉부 엑스레이 영상을 보다 자연스럽게 개선하는 것을 확인하고 discrete entropy와 saturation을 통해 정량적 평과 결과를 보인다.

• Nuclear Engineering and Technology
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• 제52권7호
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• pp.1565-1570
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• 2020

Photons with the energy of 60 keV are regularly used for some kinds of bone density examination devices, like the single photon absorptiometry (SPA). This article reports a flexible and lightweight rare earth/polymer composite for enhancing shielding efficiency against photon radiation with the energy of 60 keV. Lead oxide (PbO) and several rare earth element oxides (La₂O₃, Ce₂O₃, Nd₂O₃) were dispersed into natural rubber (NR) and the photon radiation shielding performance of the composites were assessed using monte carlo simulation method. For 60 keV photons, the shielding efficiency of rare earthbased composites were found to be much higher than that of the traditional lead-based composite, which has bad absorbing ability for photons with energies between 40 keV and 88 keV. In comparison with the lead oxide based composite, Nd₂O₃-NR composite with the same protection standard (the lead equivalent is 0.25 mmPb, 0.35 mmPb and 0.5 mmPb, respectively), can reduce the thickness by 35.29%, 37.5% and 38.24%, and reduce the weight by 38.91%, 40.99% and 41.69%, respectively. Thus, a flexible, lightweight and lead-free rare earth/NR composite could be designed, offering efficient photon radiation protection for the users of the single photon absorptiometry (SPA) with certain energy of 60 keV.

• 통상정보연구
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• 제16권5호
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• pp.225-248
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• 2014

2014년11월10일 한국과 중국은 FTA체결을 하였다. 세계의 공장 중국으로의 진출이 더욱 더 용이해졌다고 할 수 있다. 그러나 최근 중국 경제 성장이 둔화되면서 우려하는 목소리가 나오기 시작하였다. 따라서 본 연구에서는 중국 경제 성장 둔화가 한국 경제에 미치는 영향을 분석하고자 한다. 이를 위해서 현재 중국의 경제 상황에 대한 추이와 향후 앞으로의 전망을 제시하고, 중국 경제 성장을 둔화시키는 변화 조짐들을 경제 성장률 감소, 가공무역 비중 하락, 그리고 양 국가 간 품목별 경쟁관계 변화를 중심으로 분석하고자 한다. 그리고 중국 경제 성장 둔화로 인해 한국 경제에 미치는 영향에 대해 한국 경제가 대응해야 할 방안을 제시하고자 한다. 이를 분석하기 위해서 한국무역협회 무역통계 시스템을 적극 활용하고, 경쟁력 관계를 분석하기 위해 무역수지기여도지수, 무역특화도지수, 현시비교우위지수 등을 활용하여 분석하고자 한다.

• 한국건설관리학회논문집
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• 제11권6호
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• pp.65-77
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• 2010

우리나라 건설 산업에서 주택분야가 차지하는 비중은 2007년 32%정도이며 그 중에서도 공동주택은 67%이상을 차지하고 있다. 수 년 전부터 시행되고 있는 분양가 상한제와 최근의 부동산 경기침체를 고려할 때 기업의 경쟁력확보와 저렴한 주택의 공급을 위해서 원가절감의 필요성은 점점 증대되고 있다. 본 연구에서는 공동주택 중에서도 공사비의 비중이 커서 원가절감 기대효과가 높고 품질과 공기에 미치는 영향 또한 가장 큰 철근콘크리트공사 분야에서 발생된 과거의 원가절감 사례를 분류체계에 따라 분류하고, 분류체계별 상관관계를 분석하여 제외(exclusion)와 통합(integration)의 과정을 거쳐 실무적으로 활용될 수 있고 향후 다른 연구의 기초자료가 될 수 있는 공동주택 철근콘크리트공사의 원가절감 체크리스트를 제시하고자 한다.

• Molecular & Cellular Toxicology
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• 제5권4호
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• pp.346-353
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• 2009

Drug metabolism is a critical determinant of the therapeutic and adverse effects of many psychotropic drugs. The metabolism depends on the pharmacokinetics of a drug, which includes its absorption, distribution, and elimination. Psychotropic drugs are metabolized mainly by cytochrome P450 (CYP) enzymes; about 20 of these enzymes exist and they are often responsible for the rate-limiting step of drug metabolism. CYP2D6 is the best-characterized P450 enzyme that exhibits polymorphism in humans. This study determined the relationship between the CYP2D6*10 (P34S) polymorphism and the response to mirtazapine in 153 Koreans with major depressive disorder (MDD). The genotype frequencies were compared using logistic regression analysis, and between-genotype differences in the decrease in the 21-item Hamilton Depression (HAMD21) score over the 12-week treatment period were analyzed using a linear regression analysis. The proportion of remitters was lower in patients with MDD possessing the S allele than in P allele carriers after 2 weeks of mirtazapine treatment. Similarly, the reductions in the HAMD21 and Clinical Global Impression (CGI) scores in S allele carriers were smaller than those in patients with the P allele after 2 weeks of mirtazapine treatment. In the analysis of depression symptoms, the sleep and delusion scores had smaller reductions in S allele carriers. Based on the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), the psychic adverse effects of mirtazapine were associated with CYP2D6 P34S, while weight gain was not. These results suggest that CYP2D6 P34S affects the outcome of mirtazapine treatment in patients with MDD, and that this polymorphism may be a good genetic marker for predicting the clinical outcome of mirtazapine treatment.

• 한국환경복원기술학회지
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• 제12권2호
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• pp.1-9
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• 2009

Due to the increase of carbon dioxide in the atmosphere and global warming, the importance of forest ecosystems, as a place of carbon accumulation and emission, has received a great amount of recognition lately. This study was performed to help understand and provide the current status of carbon cycle in the pinus densiflora stand, Korea. The samples were collected from average 35-years-old Pinus densifiora rands in Gongju, Youngdong, Chungsan, Muju, Mupung, and Jangsu regions. Total thirty aboveground sample trees were cut, and ten roots were sampled, and soil samples were collected. Average carbon concentrations in foliage, branch, stem bark, stem wood, and root were 55.7%, 56.0%, 56.0%, 57.3%, and 56.5%, respectively. Carbon content was estimated by the model $Wt=aD^b$ where Wt is oven-dry weight in kg and D is DBH in cm. Total carbon content (aboveground and root) was 42.39tonC/ha in the Pinus densiflora stand. The proportion of each tree component to total carbon content was high in order of stemwood, root, branch, stem bark, and foliage. Total net primary production (aboveground and root) was estimated at 6.51tonC/ha/yr in Pinus densiflora stand. The proportion of each tree component to total net primary carbon content was high in order of sternwood, root, branch, foliage and stembark. Soil carbon contents in the study sites was 43.51tonC/ha at 0-50cm soil depth.

• 한국의류산업학회지
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• 제19권4호
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• pp.468-478
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• 2017

The purpose of this study is to examine the differences in appearance management behaviors and demographic variables among groups classified by the appearance management motives. The questionaries are administerd to 493 female and male adults above 20 years old in Seoul, Kyeonggi-do, Daegu and Kyungpook regions. For analysis of data from 478 respondents, descriptive statistics, factor analysis, cluster analysis, Cronbach's ${\alpha}$, ANOVA, Duncan test and ${\chi}^2$ test were applied. We show the following results: First, factor analysis for appearance management motives extracted three factors such as self-development, emphasis on the trendy appearance, and sexual appealing motive. Factor analysis for appearance management behaviors extracted four factors such as weight training, surgery/skin care, hair care and clothing selection. Second, three groups of the appearance management motives were classified into such as the social self-management type, the sexual appealing self-management type, the passive appearance management type. The social self-management groups are more interested in self-development, emphasis on the trendy appearance, and sexual appealing motive. And they are also more involved in appearance management behaviors: clothing selection is the most pursuing appearance management behavior. Third, among the demographic variables, the single and female in 20s and 30s with higher level of education belonged to the social self-management group. In this contribution, we find significant differences in the appearance management behavior and demographic variables classified by the appearance management motives.