• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.770-774
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• 2012

Protein loops are often involved in diverse biological functions, and some functional loops show conformational changes upon ligand binding. Since this conformational change is directly related to ligand binding pose and protein function, there have been numerous attempts to predict this change accurately. In this study, we show that it is plausible to obtain meaningful ensembles of loop conformations for flexible, ligand-binding protein loops efficiently by applying a loop modeling method. The loop modeling method employs triaxial loop closure algorithm for trial conformation generation and conformational space annealing for global energy optimization. When loop modeling was performed on the framework of ligand-free structure, loop structures within $3\AA$ RMSD from the crystal loop structure for the ligand-bound state were sampled in 4 out of 6 cases. This result is encouraging considering that no information on the ligand-bound state was used during the loop modeling process. We therefore expect that the present loop modeling method will be useful for future developments of flexible protein-ligand docking methods.

• Journal of The Korean Astronomical Society
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• v.37 no.5
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• pp.517-525
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• 2004

We present an update on our proposal that during the 'quasar era' (1.5 $\le$ z $\le$ 3), powerful radio galaxies could have played a major role in the enhanced global star-formation, and in the widespread magnetization and metal pollution of the universe. A key ingredient of this proposal is our estimate that the true cosmological evolution of the radio galaxy population is likely to be even steeper than what has been inferred from flux-limited samples of radio sources with redshift data, when an allowance is made for the inverse Compton losses on the cosmic microwave background which were much greater at higher redshifts. We thus estimate that a large fraction of the clumps of proto-galactic material within the cosmic web of filaments was probably impacted by the expanding lobes of radio galaxies during the quasar era. Some recently published observational evidence and simulations which provide support for this picture are pointed out. We also show that the inverse Compton x-ray emission from the population of radio galaxies during the quasar era, which we inferred to be largely missing from the derived radio luminosity function, is still only a small fraction of the observed soft x-ray background (XRB) and hence the limit imposed on this scenario by the XRB is not violated.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.32 no.2
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• pp.133-140
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• 2008

A reduced chemical kinetic mechanism is developed in order to predict the flame phenomena in premixed $CO/H_2/Air$ flames at atmospheric pressure, aimed at studying the coal gas combustion for the IGCC applications. The reduced mechanism is systematically derived from a full chemical kinetic mechanism involving 11 reacting species and 66 elementary reactions. This mechanism consists of four global steps, and is capable of explicitly calculating the concentration of 7 non-steady species and implicitly predicting the concentration of 3 steady state species. The fuel blend contains two fuels with distinct thermochemical properties, whose contribution to the radical pool in the flame is different. The flame speeds predicted by the reduced mechanism are in good agreement with those by the full mechanism and experimental results. In addition, the concentration profiles of species and temperature are also in good agreement with those by the full mechanism.

• Journal of Korean Biological Nursing Science
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• v.11 no.2
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• pp.167-175
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• 2009

Purpose: The purpose of this study was to examine the prevalence and factors on Irritable Bowel Syndrome (IBS) symptoms in university students. Methods: This study was descriptive survey research. The subjects were 187 university students from one university. The exclusion criteria were 1) had GI surgery 2) had severe physiologic or psychologic problems 3) had liver, bile duct, pancreatic, and intestinal disease that required treatment. The ROME III was used to diagnose IBS. Sociodemographic characteristics, general health state by SF-36, psychological health by SCL-90-R, stress by perceived stress scale, sleep disturbance by Korean sleep scale, and diet habits were measured. Data were analyzed by using SPSS 17.0. Results: Seventeen students (9.1%) had IBS by ROME III criteria, but 46% had some GI problems at that time. Abdominal pain or discomfort continued for last six months or more in 14.3%. Fiber intake, obsessive-compulsiveness, hostility, psychoticism, global severity index, positive symptom distress, role physical, bodily pain, social functioning, and mental health were significantly different between IBS group and Non IBS group. Conclusion: Over nine percent of the students were diagnosed by Rome III criteria, and almost half of them had some GI problems. Diet, personality, general health state, and psychological health were factors of IBS.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.1146-1151
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• 2004

Measurements of OH chemiluminescence in an atmospheric pressure, laboratory-scale dump combustor at equivalence ratios ranging from 0.63 to 0.89 were reported. The signal from the first electronically excited state of OH to ground state was detected through a band-pass filter with an ICCD. The objectives of this study are two: One is to see the effects of equivalence ratio on global heat release rate and local Rayleigh index distribution. To get the local Rayleigh index distribution, the line-of-sight images were inverted by tomographic method, such as Abel de-convolution. Another aim is to investigate the validity of using OH chemiluminescence acquired with an ICCD as a qualitative measure of local heat release. For constant inlet velocity and temperature, the overall intensities of OH emission acquired at different equivalence ratio showed periodic and higher value at high equivalence ratio. OH intensity averaged over one period of pressure increased exponentially with equivalence ratio. Local Rayleigh index distribution clearly showed the region of amplifying or damping the combustion instability as equivalence ratio increased. It could provide an information/insights on active control such as secondary fuel injection. Finally, local heat release rate derived from reconstructed OH images were presented for typical locations.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.4
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• pp.1837-1860
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• 2020

We propose a general framework for studying resource allocation problem and the tradeoff between spectral efficiency (SE) and energy efficiency (EE) for downlink traffic in power domain-non-orthogonal multiple access (PD-NOMA) and device to device (D2D) based heterogeneous cloud radio access networks (H-CRANs) under imperfect channel state information (CSI). The aim is jointly optimize radio remote head (RRH) selection, spectrum allocation and power control, which is formulated as a multi-objective optimization (MOO) problem that can be solved with weighted Tchebycheff method. We propose a low-complexity algorithm to solve user association, spectrum allocation and power coordination separately. We first compute the CSI for RRHs. Then we study allocating the cell users (CUs) and D2D groups to different subchannels by constructing a bipartite graph and Hungrarian algorithm. To solve the power control and EE-SE tradeoff problems, we decompose the target function into two subproblems. Then, we utilize successive convex program approach to lower the computational complexity. Moreover, we use Lagrangian method and KKT conditions to find the global optimum with low complexity, and get a fast convergence by subgradient method. Numerical simulation results demonstrate that by using PD-NOMA technique and H-CRAN with D2D communications, the system gets good EE-SE tradeoff performance.

• The Journal of the Acoustical Society of Korea
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• v.13 no.6
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• pp.83-90
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• 1994

In this paper, we propose a new learning algorithm, ASOFM(Adaptive Self Organizing Feature Map), to solve the defects of Kohonen's Self Organiaing Feature Map. Kohonen's algorithm is sometimes stranded on local minima for the initial weights. The proposed algorithm uses an object function which can evaluate the state of network in learning and adjusts the learning rate adaptively according to the evaluation of the object function. As a result, it is always guaranteed that the state of network is converged to the global minimum value and it has a capacity of generalized learning by adaptively. It is reduce that the learning time of our algorithm is about $30\%$ of Kohonen's.

• Journal of Environmental Policy
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• v.5 no.4
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• pp.19-49
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• 2006

As global climate change is expected to influence regional water resources, water resource managers need to establish adaptive management to cope with climate change. We examined adaptive management efforts in the US, UK, Canada, Australia, and the Netherlands. Each country is implementing different levels of adaptation efforts based on current water management practices, institutional arrangements, as well as the varying degree of water availability, current climate effects and expected climate change effects. Based on the comparison of these countries, we suggest policy implications for the sustainable water resource management of Korea under climate changes.

• Korean Management Science Review
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• v.21 no.1
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• pp.19-37
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• 2004

Since digital economy and electronic commerce are evolving rapidly. further shaping process of e-commerce over the Internet would be highly influenced by the impact of electronic commerce technologies. That is. the widespread application of electronic commerce technologies is remoulding classic business patterns and enabling organizations to deal with new ways of doing business with global suppliers. distributors, marketers and consumers. The objective of this study is to examine the scheme of electronic commerce technologies. analyzing the current state and what is expected of them In the future. However, it is difficult to clarify relationships with the every electronic commerce technology and to analyze the progress of each of them. This study focuses on the major electronic commerce application technologies relevant to e-business. In order to analyze the current state of electronic commerce technologies and relationships among them. this study has tried to gather experts' opinions using the Delphi method. For each major EC technology, this study has analyzed the current level. the technology scheme. the applicability, the economic influences of the EC technologies and the urgency of the technology development. This study will play a role of catalyser for the study of electronic commerce technologies and will provide guideline for future studies electronic commerce and information communication technology(ICT) diffusion.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.1
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• pp.143-150
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• 2012

Competition in global pork markets has increased as trade barriers have opened as a result of free trade agreements. Japanese prefer both loin and Boston butt, while Chinese prefer pork offal. Frozen pork has increased in terms of imports into China. Japanese consumers consider pork meat origin along with pork price when making purchase decisions. While the Chinese prefer a strong tasting pork product, South Korean consumers show very strong preferences to pork that is higher in fat. Therefore, South Korean consumers have a higher demand for pork belly and Boston butt. Consequently, the supply and demand of pork in Korea is hardly met, which means that importation of high fat parts is inevitable. In Korea there is lower preference toward low fat parts such as loin, picnic shoulder, and ham. During the economic depression in South Korea there have been observable changes in consumer preferences. There remains steep competition among the pork exporting countries in terms of gaining share in the international pork market. If specific consumer preferences would be considered carefully, there is the possibility to increase the amount of pork exported to these countries.