• Title/Summary/Keyword: Global Scaling Factor

Search Result 15, Processing Time 0.018 seconds

Ultimate Heterogeneous Integration Technology for Super-Chip (슈퍼 칩 구현을 위한 헤테로집적화 기술)

  • Lee, Kang-Wook
    • Journal of the Microelectronics and Packaging Society
    • /
    • v.17 no.4
    • /
    • pp.1-9
    • /
    • 2010
  • Three-dimensional (3-D) integration is an emerging technology, which vertically stacks and interconnects multiple materials, technologies, and functional components such as processor, memory, sensors, logic, analog, and power ICs into one stacked chip to form highly integrated micro-nano systems. Since CMOS device scaling has stalled, 3D integration technology allows extending Moore's law to ever high density, higher functionality, higher performance, and more diversed materials and devices to be integrated with lower cost. The potential benefits of 3D integration can vary depending on approach; increased multifunctionality, increased performance, increased data bandwidth, reduced power, small form factor, reduced packaging volume, increased yield and reliability, flexible heterogeneous integration, and reduced overall costs. It is expected that the semiconductor industry's paradiam will be shift to a new industry-fusing technology era that will offer tremendous global opportunities for expanded use of 3D based technologies in highly integrated systems. Anticipated applications start with memory, handheld devices, and high-performance computers and extend to high-density multifunctional heterogeneous integration of IT-NT-BT systems. This paper attempts to introduce new 3D integration technologies of the chip self-assembling stacking and 3D heterogeneous opto-electronics integration for realizng the super-chip.

Persicaria senticosa Ameliorates Imiquimod-induced Psoriasis-like Skin Lesions in Mice via Suppression of IL-6/STAT3 Expression and Proliferation of Keratinocytes

  • Jung, Sangmi;Park, Jeong-Ran;Ra, Moonjin;Kim, Young Han;Yu, Ji Hoon;Lee, Yongjun
    • Natural Product Sciences
    • /
    • v.26 no.2
    • /
    • pp.136-143
    • /
    • 2020
  • Psoriasis is one of the most common inflammatory skin disorders, with a global prevalence of 2% - 3%. It is an autoimmune skin disorder characterized by excessive generation of plaques on the skin with typical long-lasting red, itchy, and scaly lesions. In this study, we aimed to elucidate the anti-psoriatic effect of the methanolic extract of Persicaria senticosa (PS), a bioactive edible plant extract used in traditional medicine, using a mouse model of imiquimod (IMQ)-induced psoriasis. The daily topical application of IMQ could induce human psoriasis-like lesion. The extract ameliorated IMQ-induced psoriasis. Furthermore, hematoxylin and eosin staining and the Psoriasis Area and Severity Index (PASI) scores indicated that topical application of PS led to an improvement in erythema, scaling, and thickness scores of the mouse dorsal skin and a considerable decrease in the epidermal thickness of the ear and dorsal skin in the IMQ-induced psoriatic mouse model. We also studied the effect of PS on the proliferation of keratinocytes using HaCaT cells. The extract inhibited cell proliferation and IL-6 and pSTAT3 expression induced by M5 cocktail (comprising interleukin [IL]-1α, IL-17A, IL-22, oncostatin M, and tumor necrosis factor-α) in HaCaT cells. Thus, PS might serve as a potential therapeutic agent for the treatment of psoriasis.

The Development of Baekje Cultural Festival & Reform Measure by Using Tourist Behavior Characteristic Analysis (관광객행동특성 분석을 통한 백제문화제 발전 및 개선방안)

  • Ko, Ho-Suk
    • Journal of Global Scholars of Marketing Science
    • /
    • v.16 no.3
    • /
    • pp.125-142
    • /
    • 2006
  • The purpose of this study is to Baekje Cultural Festival development & reform measure by using tourist behavior characteristic of using a correspondence analysis. This study searches choice attributes factors to compare and analyzes satisfaction with importance of each regional culture festival based on choice attributes factor to grasp main tourists' behavioral character about visitors of Buyeo baekje cultural festival that can be called representative regional cultural festival in Korea. Also, execute confrontation agreement test that is kind of multidimensional scaling, wish to examine preference by age and by companion of Buyeo baekje cultural festivals that is regional unique festival, and contribute attract foreign tourist to korea enlargement. And analyze through multiple regression analysis whether festival choice attributes factor exerts effect that is some in revisiting intention, I wish to consider desirable development and improvement plan that can analyze problem by this strength and weakness, raise more attractive foreign tourist to korea and incomes in Buyeo baekje cultural festival hereafter.

  • PDF

Estimation and Mapping of Methane Emissions from Rice Paddies in Korea: Analysis of Regional Differences and Characteristics (전국 논에서 발생하는 메탄 배출량의 산정 및 지도화: 지역 격차 및 특성 분석)

  • Choi, Sung-Won;Kim, Joon;Kang, Minseok;Lee, Seung Hoon;Kang, Namgoo;Shim, Kyo-Moon
    • Korean Journal of Agricultural and Forest Meteorology
    • /
    • v.20 no.1
    • /
    • pp.88-100
    • /
    • 2018
  • Methane emissions from rice paddies are the largest source of greenhouse gases in the agricultural sector, but there are significant regional differences depending on the surrounding conditions and cultivation practices. To visualize these differences and to analyze their causes and characteristics, the methane emissions from each administrative district in South Korea were calculated according to the IPCC guidelines using the data from the 2010 Agriculture, Forestry and Fisheries Census, and then the results were mapped by using the ArcGIS. The nationwide average of methane emissions per unit area was $380{\pm}74kg\;CH_4\;ha^{-1}\;yr^{-1}$. The western region showed a trend toward higher values than the eastern region. One of the major causes resulting in such regional differences was the $SF_o$ (scaling factor associated with the application of organic matter), where the number of cultivation days played an important role to either offset or deepen the differences. Comparison of our results against the actual methane emissions data observed by eddy covariance flux measurement in the three KoFlux rice paddy sites in Gimje, Haenam and Cheorwon showed some differences but encouraging results with a difference of 10 % or less depending on the sites and years. Using the updated GWP (global warming potential) value of 28, the national total methane emission in 2010 was estimated to be $8,742,000tons\;CO_2eq$ - 13% lower than that of the National Greenhouse Gas Inventory Report (i.e., $10,048,000tons\;CO_2eq$). The administrative districts-based map of methane emissions developed in this study can help identify the regional differences, and the analysis of their key controlling factors will provide important scientific basis for the practical policy makings for methane mitigation.

New Estimates of CH4 Emission Scaling Factors by Amount of Rice Straw Applied from Korea Paddy Fields (볏짚 시용에 따른 벼 재배 논에서의 메탄 배출계수 개발에 관한 연구)

  • Ju, Okjung;Won, Tae-Jin;Cho, Kwang-Rae;Choi, Byoung-Rourl;Seo, Jae-Sun;Park, In-Tae;Kim, Gun-Yeob
    • Korean Journal of Environmental Agriculture
    • /
    • v.32 no.3
    • /
    • pp.179-184
    • /
    • 2013
  • BACKGROUND: Accurate estimates of total direct $CH_4$ emissions from croplands on a country scale are important for global budgets of anthropogenic sources of $CH_4$ emissions and for the development of effective mitigation strategies. Methane production resulted by the anaerobic decomposition of organic compounds where $CO_2$ acts as inorganic electron acceptor. This process could be affected by the addition of rice straw, water management and rice variety itself. METHODS AND RESULTS: Rice (Oryza sativa L. Japonica type, var Samkwangbyeo) was cultivated in four plots: (1) Nitrogen-Phosphorus-Potassium (NPK) ($N-P_2O_5-K_2O$:90-45-57 kg/ha); (2) NPK plus 3 Mg/ha rice straw (RS3); (3) NPK plus 5 Mg/ha rice straw (RS5); (4) NPK plus 7 Mg/ha rice straw (RS7) for 3 years (2010-2012) and the rice straw incorporated in fall (Nov.) in Gyeonggi-do Hwaseong-si. Gas samples were collected using the closed static chamber which were installed in each treated plot of $152.9m^2$. According to application of 3, 5, 7 Mg/ha of rice straw, methane emission increased by 46, 101, 190%, respectively, compared to that of the NPK plot. CONCLUSION(S): We obtained a quantitative relationship between $CH_4$ emission and the amount of rice straw applied from rice fields which could be described by polynomial regression of order 2. The emission scaling factor estimated by the relationship were in the range of IPCC GPG (2000).