• Proceedings of the Ginseng society Conference
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• 1990.06a
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• pp.75-78
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• 1990

Two lignanes, Comp.-I, mp 108-1$0^{\circ}C$ and Comp.-II, mp 50-52$^{\circ}C$ were isolated from Korean ginseng extract by repeated column chromatographic purification. Comp-1 was identified as gomisin-N and Comp. -II as gomisin-A by spectrometric analysis, both of which have already been described as the anti-hepatotoxic lignin components of Schizandra chinensis Bail.

• Journal of Ginseng Research
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• v.15 no.3
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• pp.188-191
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• 1991

The mild hydrolysis of ginsenosie Re with 50% acetic acid gave a prosapogenin mixture, 20(R)- and 20(S)-ginsenoside Rg2. The products were acetylated to give the peracetates, which were further converted into 20(R)- and 20(S)-ginsenoside Rh1 by the alcoholic alkaline treatment.

• Journal of Ginseng Research
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• v.23 no.3 s.55
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• pp.176-181
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• 1999

The purpose of this study was to investigate the antioxidant activities of water soluble browning reaction products (WS-BRPs) isolated from korea red ginseng. Antioxidant activities of WS-BRPs were examined with the various systems. All three WS-BRPs (L, S-1 and S-2) were found to have an ability to donate hydrogen to DPPH. Especially, L was more effective than S-1, S-2. and, L as well as S-1 and S-2 was the strongest than BHT, BHA $(5{\times}10^{-4}M),\;{\alpha}-tocopherol\;(1.0{\times}10^{-4})$ and ascorbic acid $(5.7{\times}10^{-3}M)$ previously known as antioxidants. These WS-BRPs (L, S-1 and S-2) also showed a synergistic effect against antioxidative activities of these antioxidants. Moreover S-2 had the strongest activity of these three WS-BRPs to scavenge free radicals such as hydrogen peroxide $(H_2O_2)$.

• The Journal of Society for e-Business Studies
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• v.7 no.2
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• pp.1-19
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• 2002

Lately, the Korean ginseng was confronted with the sale crisis in world markets from the various circumstance. One of important difficulties is overspreading of Korean ginseng imitative in foreign markets. In Korean markets also, chinese ginseng was imported illegally and manufactured as Korean ginseng, which was resulted in the damage of Korean ginseng brand. The most essential problem is misunderstanding of Korean ginseng's information in the foreigner. In this paper, we developed a genuine guarantee system to identify the true Korean ginseng through internet and geographic cording system of Korean ginseng products. This system can be applied to the enforcement of Korean ginseng sale to international markets.

• Archives of Pharmacal Research
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• v.17 no.5
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• pp.389-391
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• 1994

• Journal of Ginseng Research
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• v.17 no.3
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• pp.287-306
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• 1993

• Bulletin of the Korean Chemical Society
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• v.30 no.6
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• pp.1385-1387
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• 2009

• Archives of Pharmacal Research
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• v.13 no.3
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• pp.278-281
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• 1990

Two lingans were isolated from hexane-soluble fraction of Korean red ginseng. Their chemical structures were elucidated as gomisin N and gomisin A by spectrometric analysis.

• The Korean Journal of Food And Nutrition
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• v.22 no.2
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• pp.199-204
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• 2009

For the purpose of developing a safe & hygienic manufacturing method to acquire low levels of benzo(a)pyrene in black and red ginseng products, this study investigated the effects of steam- and dry-processing temperatures on benzo(a)pyrene production in ginseng. By the red ginseng with a fix dry-process temperature of $50^{\circ}C$ and setting the steam-process temperature between $80{\sim}120^{\circ}C$, an extremely small amount(0.1 ppb) of benzo(a)pyrene was produced, indicating there was no relationship between the steam-temperature and benzo(a)pyrene production. On the other hand, when the red and black ginseng were steamed at the fixed temperature of $100^{\circ}C$ and dried at various temperatures between $50{\sim}120^{\circ}C$, the amount of benzo(a)pyrene produced was closely connected with the dry-temperature, and increased with higher drying temperatures. Upon repeating the steam and dry process nine times, in which the steam-temperature was set at $100^{\circ}C$ and the dry-temperature at $50^{\circ}C$, higher amount of benzo(a)pyrene were produced in red and black ginseng, respectively, with increasing steam- and dry-processing time. However, the level of benzo(a)pyrene still remained extremely small(below 0.12 ppb), showing a maximum amount in the black ginseng that was steamed and dried nine times. This suggests that the fine root of ginseng may be carbonized by increasing the number of times it is steam- and dry-processed. From the above results, this study determined that the optimum temperatures for manufacturing red and black ginseng products with safe levels of benzo(a)pyrene would be a temperature between 80 and $120^{\circ}C$ for steaming and a temperature less than $50^{\circ}C$ for drying.

• Journal of Ginseng Research
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• v.14 no.2
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• pp.253-264
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• 1990

The growth responses of a variety of human intestinal bacteria to extracts of Panax ginseng and five other oriental medicinal Araliaceae were elraluattd in vitro and in vivo. The extracts enhanced the growth of Brifidobnnerilrm breve and B. longlim in media with or without carbon sources, suggesting that bifidus factors) might be involved in the phenomenon. This effect was most pronounced with water extract of P. ginseng, the growth of 27 bifidobacteria strains belonging to B adolescentis, B. longum, B. brim and B. infantis being greatly stimurated, whereas seven B. bifidum strains and other bacteria such as clostridia and Escherichin soli had little or no ability to utilise it for growth. Methanol extracts of p. ginseng were found to selectively inhibit growth of various clostridia including bifidobacteria. Paraputrificum, but this effect was not observed on other bacteria including bifidobacteria. The effect of ginseng extract intake (600 mg/day for two weeks) on the faecal microflora, pH, volatile fatty acids, ammonia, putrefactive products, and -glucuronidase, -glucosidase and nitroreductase activities, and on the blood components (triglyceride, total cholesterol and ammonia) were investigated using seven healthy human volunteers. The total concentration of faecal microflora including Bifidnkaderiifm app. during the period of ginseng extract intake %twas significantly unaffected from the preceding and subsequent control peroids. However, the frequency of occurrence of subjects having C. perfringens was significantly decreased. The faecal pH value was also significantly decreased, suggesting that the intake might increase the activity of Bifidobncterium spry. Other biochemical properties in faeces did not changed significantly. The levels of ammonia and triglycerid in blood were decreased with ginseng extract intake. These results may be an indication of at least one of the Pharmacological actions of p. ginseng as an adaptogen.