• 한국동물학회:학술대회논문집
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• 한국동물학회 1995년도 한국생물과학협회 학술발표대회
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• pp.176.1-176
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• 1995

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.166.2-167
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• 2003

The important biological activities of estrogen were reproduction and physiological processes in a number of tissues, including liver, bone, brain, blood vessels, adipose tissue and so on. The regulation of estrogen level is important a prevention of estrogen-related disease. Ginkgo biloba extracts (GSE) are extracted from leaves of the Ginkgo biloba tree. GSE contains 24％ phytoestrogen, which are kaempferol, quercetin, and isorhamnetin. (omitted)

• The Korean Journal of Ecology
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• 제13권3호
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• pp.165-172
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• 1990

The contents of Pb and Cd in litters of Ginko biloba collected from thirty-four areas in Seoul were measured and analyzed for among relative air pollutions. S contents in litters of G. biloba were 0.88% at Hyehwadong, 0.98% at Yongsan and 0.95% at Ch angdong. Mean value were 0.65% in 0-10 km areas from Kwanghwamun, but were 0.47% in 10-15 km areas. In S contents, the correlation between 0-5 km area and 10-15 km area from Kwanghwamun was high significant, but correlation between 0-5 km area and 5-10 km area from Kwanghwamun had no significance. Pb contents were 118.95 ppm at Pildong, 112.22 ppm at Ulchiro 3-ga and 105.55 ppm at Bus terminal (Banpo). In Pb contents the correlation between 0-5 km area and 10-15 km aea from kwanghwamun was high significant, but the correlation between 0-5 km area and 5-10 km area from Kwanghwamun had no significance. In Cd contents. Cd contents were high in Youido, Shinch on, Kongdokdong, Haengdangdong, Kirum, Ch ongnyangni and Imundong.

• 한국자원식물학회지
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• 제31권3호
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• pp.268-273
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• 2018

Hepatic ischemia-reperfusion injury (HIRI) is linked with high mortality rate. Several agents have been developed so far to reduce the risk of HIRI. In this study, we investigated the effects of combined treatment of Ginko biloba leaves extract and vitamin C (GLEVC) on hepatic ischemia-reperfusion injury. To explore the protective effects of GLEVC on HIRI rats model were tested. After the development of HIRI by using clamping method rats were then randomly divided into four groups. Different doses of GLEVC were administered in HIRI rat model. The level of ALT, AST, SOD and MDA content in serum were detected in HIRI groups. Moreover, the activity of SOD, content of MDA, and GSH in hepatic tissue were also examined. Bcl-2 and Bax protein expression were detected by immunohistochemical staining method. Compared with sham group, GLEVC has the protective effect on the HIRI-induced model. Level of ALT, AST, and MDA in blood were significantly lower in GLEVC group compared with HIRI-induced group. Moreover, SOD activity and GSH were increased in GLEVC group whereas MDA content was reduced by GLEVC treatment. Furthermore, HIRI-induced Bax protein was reduced upon GLEVC treatment, whereas Bcl-2 protein expression was enhanced. These results demonstrate that GLEVC treatment may provide potential ameliorative therapy by reducing damaged signaling mechanism in hepatic ischemia/reperfusion injury model.

• 한국환경생태학회지
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• 제30권3호
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• pp.415-422
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• 2016

본 연구는 천연기념물로 지정된 소나무와 은행나무를 중심으로 수목활력도를 측정하고, 관리시설물에 따른 노거수의 수목활력도 차이를 규명하였다. 수목활력도 측정 결과 소나무의 전기저항 값은 평균 $14.9K{\Omega}$이고, $8.5{\sim}37.5K{\Omega}$사이에 분포하며, 은행나무의 전기저항 값은 평균 $13.5K{\Omega}$로, $6.4{\sim}40.5K{\Omega}$사이에 분포하는 것으로 나타났다. 관리시설물 현황조사 결과 소나무, 은행나무 모두 과반수 복토 및 석축이 이루어졌고, 특히 복토 여부에 따라 수목의 활력에 유의한 차이가 있었다. 소나무와 은행나무 모두 복토 된 수목의 형성층 전기저항 값이 복토되지 않은 수목보다 유의하게 높게 나타나 상대적인 생육상태가 불량한 것으로 나타났다. 따라서 복토를 제거하는 방향으로 관리가 필요하며 천연기념물로 지정된 노거수 외 지자체에서 관리하고 있는 보호수에 대한 관리방안 실태조사도 실시하여 전반적인 복토 제거 등 관리시설물 개선이 필요할 것으로 판단된다.

• 대한본초학회지
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• 제22권2호
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• pp.45-50
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• 2007

objectives: We investigated the moisturizing and cooling effects of the cosmetic product with Scrophularia Buergeriana, Poria Cocos, Lonicera Japonica, Portulaca Oleracea and Ginko Biloba extract on human skin by using non-invasive instrument. Methods: We measured physiological effects after volunteers(female, n=5) applied the cosmetic product containing the extract of oriental herbs. The forearm skin moisturization was measured with $Corneometer^{\circledR}$ CM825 after 15min, 3hr, and 6hr. The forearm skin surface roughness was with Scanning electron microscopy after 15min, and 6hr. The face skin temperatures cooling and microcirculation effects were measured with ThermaCAMTM PM525 and LDl-Periscan PlM II after 15min, and 30min. Results: The forearm skin moisturization was imcreased 108% after 15min. The forearm skin surface roughness was decreased significantly after 15min. The face skin temperatures were cooling down to $30.7^{\circ}C$. The face skin microcirculation effect was normalized time-dependently. Conclusions: We concluded that cosmetic product containing the extract of Scrophularia Buergeriana, Poria Cocos, Lonicera Japonica, Portulaca Oleracea and Ginko Biloba had a moisturization effect and improving the surface roughness, temperature and microcirculation on the human skin.

• 생약학회지
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• 제33권1호통권128호
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• pp.49-52
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• 2002

Amentoflavone, naturally occurring biflavonoid, isolated from the leaves of Ginko biloba, selectively inhibited human seceretory phospholipase $A_2$. This compound potently and irreversibly inhibited human group IIA in a dose dependent manner with an $IC_50$ about $3\;{\mu}M$. Amentoflavone inhibited phospholipase $A_2$ by a noncompetitive manner with the apparent Ki value of $1{\times}10^{-5}M$. In addition, the inhibitory activity of amentoflavone is rather specific against group IIA phospholipase $A_2$ than group IB phospholipase $A_2$. Furthermore, this compound strong inhibit histamine release from $A_{23187}$ treated rat peritoneal mast cells. These results indicate naturally occurring biflavonoid represents a novel anti-inflammatory agent.

• Toxicological Research
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• 제14권3호
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• pp.401-409
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• 1998

Group of 40 male and 40 female ICR mice was given daily per oral treatment with the combination of enalapril plus Ginkgo biloba extract (EGb 761), 3+9mg/kg/day(low dosage group), 10+30mg/kg/day (middle dosage group), 30+90mg/kg/day (high dosage group) for 3 months in drinking water according to Established Regulation of Korean National Institute of Safety Research (1994. 4.14). Appearance, behavior, mortality, and food consumption of mouse of treated groups were not affected during the experimental periods. No significant the combination of enalapril plus Ginkgo biloba extract (EGb 761)-related changes were found in urinalysis, hematology, serum chemistry, and organ weight, Lung edema were observed and the weight of lung were increased in low dosage treated group of the male mice, which be associated with enalapril treatment, but these changes were not found in middle and high dosage group. Our results suggest that to toxic changes were found in rat treated orally with the combination of enalapril plus Ginko biloba extract (EGb 761) for 3 months.

• 한국식품과학회지
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• 제38권6호
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• pp.779-784
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• 2006

기능성 강화를 목적으로 키토산 0.2%, 송이버섯 1.0%, 석류분말 1.2%, 산사추출분말 1.0%, 실크분말 1.2%, 은행잎추출분말 0.01%, 동아분말 1.2%, 마늘유 0.2%, 홍국분말 1.2%를 각각 첨가하여 고추장을 제조하였다. 각각의 소재가 고추장의 숙성에 미치는 영향을 조사한 결과 45일간의 숙성 기간별 pH, 산도, 포르몰태 질소함량, 색도의 변화는 소재 첨가구와 control 간에 큰 차이가 없었다. 항산화활성은 0.2%의 마늘유 첨가구가 control에 비해 약 2배 증가하였고 ACE저해활성은 1.2%의 실크분말 또는 0.01%의 은행추출분말 첨가 시 control에 비해 약 2배의 효과가 있었다.

• 한국환경과학회지
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• 제26권8호
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• pp.993-998
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• 2017

De-icing salts applied to roads during winter enable safe driving conditions. However, these salts are eventually displaced to roadside areas at which they can negatively impact soil, vegetation, and water resources. This purpose of this study is to determine the relationship between foliar damage ratio (NY = 0-25%, SY = 26-50%, CY = 51-75%) on roadside trees (Ginko biloba) and seasonal impact of de-icing salts on soil and vegetation. Thirty roadside trees were selected at 8 m intervals between the Konkuk and Judeok intersections in Chung-ju city. The results reveal that seasonal soil acidity is relatively alkaline for foliar damage ratio of Ginko biloba was CY compared to NY. Also, electronic conductivity of each seasonal sampling was recorded as high in winter and spring, whereas the opposite trend is observed in summer. Various plants species were identified in abundance under roadside trees within NY roadside sections. These same species were observed in reduced numbers within CY sections. Strong negative correlations were identified between foliar damage ratio on roadside trees and vegetation. This relationship may be a method to use in predicting the accumulation of de-icing salt and visible injuries on roadside trees.