• YAKHAK HOEJI
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• v.45 no.1
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• pp.93-100
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• 2001

Drug inetraction between of enalapril-induced angiotensin converting enzym) inhibitory effect and Ginkgo biloba Ext.-induced antioxidant action was evaluated in spontaneously hypertensive rats. Combination treatment of enalapril (20 mg/kg/day p.o.) and Ginkgo biloba Ext. (60 mg/kg/day, p.o.) for 6 weeks in drinking water to SHRs resulted the inhibition of ACE activity in lung tissue, angiotensin I-induced pressure response and plasma angiotensin II concentration as similar to enalapril alone treatment. But these effects were sustained after 1 week withdrawal of enalapril and Ginkgo biloba Ext. co-administeration. Also, coadministered group did not increase the concentration of bradykinin in lung tissue, which were different from enalapril alone treated group. Co-administration of enalapril and Ginkgo biloba Ext. inhibited the hemolysis induced by UV B type, even Ginkgo biloba Ext. alone treated group did not. These results suggested that Ginkgo biloba Ext. sustained ACE inhibitory effect and reduced the inhibitory effect of bradykinin inactivation induced by enalapril, meanwhile, enalapril increased the antioxidant effect of Ginkgo biloba Ext.

• Korean Journal of Food Science and Technology
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• v.36 no.3
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• pp.410-415
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• 2004

Effects of ginkgo nut powder content on physical and sensory properties, and consumer acceptability of ginkgo nut gruel and cake were examined. In ginkgo nut gruel, greenness and consistency decreased, and sensory color intensity and ginkgo nut flavor increased with increasing ginkgo nut powder content. Consumer acceptability test indicated ginkgo nut powder : rice flour ratio at 4 : 6 had the highest overall and flavor acceptabilities. In ginkgo nut rice cakes, as ginkgo nut powder content increased, greenness, adhesiveness, sensory hardness, and cohesiveness of mass decreased, while sensory color intensity, ginkgo nut flavor, and chalkiness increased. Ginkgo nut cake with ginkgo nut powder : rice flour ratio at 16 : 84 had highest overall acceptability.

• Journal of the Korean Society of Food Culture
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• v.29 no.1
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• pp.84-90
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• 2014

This study investigated the effects of ginkgo nut powder on the antioxidant activity and quality characteristics of mung bean starch gel. Mung bean starch gels were prepared with different amounts of ginkgo nut powder (0, 1, 3, 5, and 7%). The antioxidant activity of ginkgo nut powder and mung bean starch gel was estimated through measuring DPPH free radical scavenging activity and total phenolic acid content. For analyzing quality characteristics several factors were considered: syneresis, pH, color, texture profile analysis, and sensory evaluations. In the results, syneresis in the treated group was higher than the control group. The pH, b values, total phenolic acid content, and DPPH free radical scavenging activity of mung bean starch gels also significantly increased with increasing ginkgo nut powder. In contrast, the L values and a values of mung bean starch gels significantly decreased with increasing ginkgo nut powder. In the texture profile analysis, the mung bean starch gels with 5% and 7% ginkgo nut powder showed significantly lower degrees of hardness, chewiness, and gumminess. On the other hand, cohesiveness was highest in the mung bean starch gels with 5% and 7% ginkgo nut powder. The consumer acceptability score for the mung bean starch gel prepared with 5% and 7% ginkgo nut powder ranked significantly higher than the other groups in flavor and taste. Overall, these results suggest that ginkgo nut powder is a good ingredient for increasing the consumer acceptability and functionality of mung bean starch gel.

• The Korea Journal of Herbology
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• v.20 no.4
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• pp.11-16
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• 2005

Objectives : This study was designed to propose the effective herb-processing method of Ginkgo Folium in the Oriental medicine. Methods : The books, papers and patents were used to examine the recent usage of Ginkgo Folium. Results : The toxic ingredients of Ginkgo Folium should be removed. Accordingly, a detoxification process using a nonpolar solvent and a vinegar-roasting process in sequence are desirable to assure its safety. The previously developed standard extract (e.g. EGb 761) could be used as a powdered Oriental medicine as well. Conclusions : Ginkgo Folium could not be used widely to treat the diseases in ancient Oriental medicine, because the toxic ingredients could not be removed by any method until recent year. However, Ginkgo Folium might be used as a herbal medicine that invigorates the blood without any difficulty using herb-processing methods suggested in this paper.

• YAKHAK HOEJI
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• v.35 no.4
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• pp.271-276
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• 1991

The extractability and stability of ginkgoflavonolglycosides under presence of several cellulose preparations were investigated. The enzymes used were macerosin, cellulose C and cellulase NC. The content variation of the glycosides was measured with HPLC method, using caffeic acid as an internal standard. The methanol extract of ginkgo leaf, containing the total flavonolglycosides of 4.46%, was used for the content comparison. By extraction with the enzymes, each or mixed, the peak levels of all the glycosides began to decrease after 1 or 2 hours. After 24 hour extraction, most of the glycosides were degraded to minor components. The flavonolglycosides in ginkgo leaf were also hydrolysed simply by the water extraction. After 24 hour extraction with water at $40^{\circ}C$, the peak levels of major glycosides were distinctly decreased. Rutin was hydrolysed by enzyme treatment or by ginkgo leaf itself. As a result, it was concluded that the commercially available cellulases and the ginkgo leaf itself contain the activities of $\beta$-glycosidase and $\alpha$-rhamnosidase. Kaempferol-3-O-(6'"-O-p-coumaroylglucosyl)-rhamnoside and four other ginkgo flavonolglycosides were not hydrolysed under the same condition.tion.

• Journal of the Korea Furniture Society
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• v.11 no.2
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• pp.37-43
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• 2000

Ginkgo trees have long been planted in Korea as roadside trees and ornamental trees, but the wood was seldom used except some utilization f3r small artifacts. Soaring prices of imported wood and future uncertainty about long-term supply of foreign woods have stimulated research on value-added utilization of less-utilized domestic wood resources such as Ginkgo wood. The processing properties of Ginkgo wood were investigated to determine its utilization potential in this study, and the results of treatability, drying characteristics, gluability, paintability, bending properties, chemical discoloration characteristics were presented.

• Journal of the Korea Furniture Society
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• v.11 no.1
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• pp.75-84
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• 2000

Ginkgo trees have long been planted in Korea as roadside trees and ornamental trees, but the wood was seldom used except some utilization for small artifacts. Soaring prices of imported wood and future uncertainty about long-term supply of foreign woods have stimulated research on value-added utilization of less-utilized domestic wood resources such as Ginkgo wood. The properties of Ginkgo wood were investigated to determine its utilization potential in this study, and the results of anatomical, physical, and mechanical studies were presented with chemical compositions.

• Research in Plant Disease
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• v.9 no.2
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• pp.99-103
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• 2003

Bioactivities of Korean ginkgo (Ginkgo biloba L.) extract were investigated against several fungi, general bacteria and insect pests. Crude methanolic extracts of different parts of Korean ginkgo showed different bioactivities depending on the target organisms. The methanolic extract showed in vitro antimicrobial activity at dose of 200 ug per paper disc. The extract of ginkgo stalk was some higher than seed coat and root. The extract also showed a remarkable in vivo antifungal activity against green mold (Trichoderma harzianum) on compost surface of spawn bags and in vivo insecticidal activity to Nilaparvata lugens, Plutella xylostella and Tetranychus urticae. This study suggests that Korean ginkgo extracts have a potential as a natural pesticide.

• Korean Journal of Soil Science and Fertilizer
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• v.30 no.4
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• pp.341-344
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• 1997

To check the possibility to use the pharmaceutical by product of ginkgo leaf for the improvement soil fertility, a pot experiment was conducted with paddy rice. There were three treatment; NPK alone, NPK+7000kg(air dry)/ha of ginkgo leaf waste and NPK+700 kg of water-washed ginkgo leaf waste (air dry)/ha. The result indicated that the application of ginkgo leaf waste severely retarded the growth of rice. Water washing did reduce the severity of retardation, but the water washed ginkgo leaf waste also retarded the growth of rice significantly. The result of this study suggested that ginkgo leaf waste may contain some growth inhibiting substance.

• Toxicological Research
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• v.12 no.1
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• pp.137-141
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• 1996

A teratological study was performed using New Zealand White rabbits to examine the teratological potential of Ginkgo biloba extract(EGb 761), which is a known strong platelet activating factor antagonist. Ginkgo biloba extract(EGb 761) was administered per intravenously during the organogenesis period (day 6th to 18th of gestation) of rabbits at dose levels of 7.5, 15, and 30 mg/kg/day. All pregnant females were sacrificed on day 29 of gestation and teratological abnormalities of their fetuses was examined. No statistically significant difference of body weight change between control and treated groups during experimental periods was noted. There was no statistically signifiant difference of numbers of corpus lutes and implantations, fetal death ratio, fetal sex ratio, and placental weight between control and rabbits exposed to three different concentration ranges of Ginkgo biloba extract (EGb 761). No marked external, visceral and skeletal abnormalities related to Ginkgo biloba extract(EGb 761) were observed in the fetuses. In conclusion Ginkgo biloba extract(EGb 761) does not show any effect on implantation or embryonic development.