• 한국융합학회논문지
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• 제12권3호
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• pp.317-323
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• 2021

본 연구의 목적은 청소년의 체질량지수에 따른 구강증상 경험을 분석하고자 함이다. 청소년건강행태조사 자료를 이용하여 총 55,728명을 대상으로 복합표본분석을 실시하였다. 민감성 치아, 치아통증, 치은출혈 및 부종의 경험은 각각 과체중 그룹(36.8%, 23.9%, 19.2%)에서 가장 높고 저체중 그룹(34.6%, 20.8%, 17.0%)은 가장 낮았으며, 구취경험은 비만 그룹이 26.7%로 가장 높고 저체중 그룹은 18.8%로 가장 낮았다(p<0.001). 정상체중을 기준으로 했을 때 치아통증 경험은 과체중 그룹이 1.08배(95%CI: 1.01-1.15) 유의하게 높았고 치은출혈 및 부종 또한 과체중 그룹에서 1.08배(95%CI: 1.01-1.16) 유의하게 높았다. 구취경험은 과체중 그룹에서 1.19배(95%CI: 1.11-1.27), 비만 그룹에서 1.43배(95%CI:1.35-1.52) 유의하게 높았다. 차후 전신건강과 구강건강에 관한 보다 다양한 연구가 필요할 것이다.

• Journal of Periodontal and Implant Science
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• 제44권3호
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• pp.126-133
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• 2014

Purpose: Smokeless tobacco-based oral-use products like gutka are popular in India. Gutka usage leads to increased periodontal destruction and inflammation; however, the relevant mechanism remains unknown. This study aimed to elucidate the role of gutka in periodontitis by examining its effect on the levels of interleukin (IL) $1{\beta}$ and IL-8 from the gingival crevicular fluid (GCF). Methods: A total of 45 patients were enrolled in this study. Thirty patients with periodontitis (15 gutka chewers [GCP] and 15 nongutka chewers [NGC]) and 15 periodontally healthy controls (HC) were selected. The full-mouth plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), and recession (RC) were recorded. The IL-$1{\beta}$ and IL-8 levels in the GCF of all subjects were assessed through an enzyme-linked immunosorbent assay (Quantikine). Results: The IL-$1{\beta}$ and IL-8 levels were not significantly higher in the GCP group (IL-$1{\beta}$, $369.01{\pm}273.44{\mu}L$; IL-8, $205.97{\pm}196.78{\mu}L$) as compared to those in the NGC group (IL-$1{\beta}$, $195.57{\pm}96.85{\mu}L$; IL-8, $178.61{\pm}149.35{\mu}L$). More gingival RC and loss of attachment was seen among the GCP group (RC: $2.02{\pm}0.31$, P=0.013; CAL: $4.60{\pm}0.56$, P<0.001) than among the NGC group (RC, $1.21{\pm}1.15$; CAL, $3.70{\pm}0.32$); however, PD was deeper among the NGC subjects (P=0.002). PI and GI were significantly higher for the periodontitis group (P<0.001) when compared to the HC, but there was no difference among gutka chewers and non-chewers (P=0.22 and P=0.89). A positive correlation was found between the IL-8 levels and the duration of gutka chewing (r=-0.64, P<0.01). Conclusions: Gutka chewing leads to increased gingival RC and clinical loss of attachment. There was no effect seen in the proinflammatory cytokine levels in the GCF of gutka users.

• Journal of Periodontal and Implant Science
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• 제30권1호
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• pp.111-120
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• 2000

Purpose We designed this study for the purpose of determining the relationship between periodontal disease activity and PLBW, using the evaluation of probing pocket depth, loss of attachment, gingival index, gingival crevicular fluid amount and subgingival microflora. Methods A total of 100 volunteer mothers(mean age 30.44) at the Department of Obstetrics and Gynecology Seoul National University Hospital were selected for this study.Pregnancy outcomes were categorized into cases and controls in two ways. our definition was based on the following; Group 1 : Any PLBW cases Vs. All NBW controls Group 2 : PLBW cases Vs. NBW controls A periodontal exam was performed on the Ramfjord( #16, 21, 24, 36, 41, 44) teeth and Clinical evaluation consisted of probing pocket depth, loss of attachment, gingival index and gingival crevicular fluid amount. Subgingival plaque samples were collected by three sterile #35 paper points. The total number of anaerobic colonies and aerobic bacteria were enumerated after incubation. Antisera to P. gingivalis, P. intermedia, A. actinomycetemcomitans were produced in white rabbits with live whole cells suspensions. The specific fluorescent bacteria obtained by immunofluorescence and total cell counts obtained by dark-field microscopy were counted on four fields. The percent of each specific microorganism in the total cell count was determined. Results Any PLBW and PLBW cases showed significantly greater probing depth and attachment loss than all NBW and NBW controls. Cases group had significantly increased anaerobic bacterial counts compared with control group and no differences in the other microbes. This study confirmed that periodontal disease is a statistically significant risk factor for PLBW by investigating clinical parameters and subgingival plaque analysis.

• 대한소아치과학회지
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• 제4권1호
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• pp.28-34
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• 1977

The present study was undertaken to evaluate gingivitis and oral hygiene status of the crowned teeth comparing to controlled teeth by use of P. M. A. Index and Oral Hygiene. Index in children from $3\frac{1}{2}$ to $7\frac{1}{2}$ years old. The results were as followings. 1. In P. M. A. Index, satisfactory crowned teeth (1.53) showed statistically significant increment compare to the controlled teeth (0.68) (P<0.01). 2. In P. M. A. Index, unsatisfactory crowned teeth (2.22) showed statistically significant increment compare to the controlled teeth (0.70) (P<0 01). 3. In Oral Hygiene Index, satisfactory crowned teeth (1.49) showed statistically nonsignificant increment compare to the controlled teeth (1.27). 4. In Oral Hygiene Index, unsatisfactory crowned teeth (1.62) showed statistically nonsignicant increment compare to the controlled (1.39) 5. The severity of gingivitis following Oral Hygiene Index showed higher in crowed teeth than the controlled teeth. 6. The severity of giginvitis showed the highest in the unsatisfactory crowned teeth, the next was the satisfactory crowned teeth, and the controlled teeth showed the lowest.

• 치위생과학회지
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• 제12권6호
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• pp.583-590
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• 2012

본 연구는 경제적 스트레스와 상태 특성불안이 치주질환에 미치는 영향을 파악하여 치주질환의 예방과 발생 및 진행 정도를 미연에 방지할 수 있는 방안을 마련하기 위하여 실시되었다. 연구대상은 일부 지역 치과의원에 내원한 40~50대 성인남녀 총 326명을 대상으로 하여 구조화된 설문지와 치주상태를 측정하여 조사 분석하였다. 수집된 자료는 IBM SPSS ver. 19.0 통계프로그램(IBM Co., Armonk, NY, USA)을 이용하여 빈도와 백분율, t-test (검증), One way ANOVA (일원배치 분산분석), Multiple regression Analysis (다중회귀분석)을 실시하여 분석결과는 다음과 같다. 1. 경제적 스트레스는 치은염 지수의 고($1.12{\pm}0.72$), 중($0.85{\pm}0.62$), 저($0.88{\pm}0.62$)에 따라 통계적으로 유의한 차이를 보였다(p<0.01). 2. 상태 특성불안은 치은염 지수(p<0.001)의 고($1.16{\pm}0.71$), 중($0.81{\pm}0.63$), 저($0.86{\pm}0.60$), 치주낭 깊이(p<0.05)의 고($3.86{\pm}1.12$), 중($3.44{\pm}1.07$), 저($3.57{\pm}1.01$), 임상적 부착소실(p<0.05)의 고($3.86{\pm}1.12$), 중($3.44{\pm}1.07$), 저($3.57{\pm}1.01$)에 따라 통계적으로 유의한 차이를 보였다. 3. 치은염 지수에 영향을 미치는 요인으로 경제적 스트레스($\beta$=0.052, p<0.01)가 높을수록, 상태 특성불안($\beta$=0.052, p<0.01)이 높을수록 영향을 미치는 것으로 조사되었다. 이상의 연구결과에서 치과의료기관은 치주질환으로 힘들어 하는 환자에게 경제적 스트레스와 상태 특성불안이 치주질환에 영향을 미친다는 사실을 인식시킬 필요가 있으며 이에 따른 치주질환의 예방과 발생 및 진행 정도를 방지할 수 있는 스트레스 관리능력배양을 위한 교육프로그램 개발이 마련되어야 할 것이다.

• 한국치위생학회지
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• 제1권1호
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• pp.77-87
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• 2001

The authors have studied the 8 weeks clinical experiment on 34 dental patients of age 20s for control group and 32 for experimental 1 group(Paste Type Dentifrice with Bamboo Salt, Chitosan and Powder of Pine Needles and Leaves of Bamboo.) and 32 for experimental 2 group(Powder Type Dentifrice with Bamboo Salt, Chitosan and Powder of Pine Needles and Leaves of Bamboo), in order to find out the effect of plaque removal, prevention of calculus and stain formation. and Gingival effect. The obtained results are as following. 1. Plaque removal effect was the similar level on group 1 and on group 2 as control group. 2. For prevention of calculus formation, there was a little bit better on group 1 at 8 weeks, and for prevention of stain formation, it revealed more or less difference between on group 1, group 2 and control group at 8 weeks. 3. on PMA index, it revealed the significantly differences between group 1, group 2 and the control group at 8 weeks(p<0.05), so it is estimated that there might be signified for gingival subside effect by use of dentifrice with Bamboo Salt, Chitosan and Powder of Pine Needles and Leaves Bamboo.

• Journal of Periodontal and Implant Science
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• 제31권4호
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• pp.689-711
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• 2001

The purpose of this study was to compare clinical results of guided tissue regeneration(GTR) using either a nonresorbable ePTFE membrane or a resorbable membrane made from a synthetic copolymer of glycolide and lactide(PLGA) in the treatment of human class Ⅱ furcation defects. The ePTEE membranes were applied to 16 patients with maxillary molar buccal class Ⅱ furcation defects as Group I, PLGA membranes were applied to 15 patients with maxillary molar buccal class Ⅱ furcation defects as Group Ⅱ, ePTFE membranes were applied to 20 patients with mandibular molar buccal class Ⅱ furcation defects as Group Ⅲ and PLGA membranes were applied to 20 patients with mandibular molar buccal class Ⅱ furcation defects as Group Ⅳ and bone graft materials(DFDBA) were applied in all groups. Probing depth, gingival recession, clinical attachment level, tooth mobility and sulcus bleeding index(SBI) were measured at baseline, 3, 6 and 12months postoperatively. In addition, membrane exposure levels were measured at surgery, 1, 2 and 6weeks postoperatively and postoperative complications were evaluated. The results were as follows: In all groups, there were statistically significant differences in probing depth reduction, gain of clinical attachment and mobility reduction at values of 3, 6 and 12months postoperatively compared to values of baseline, whereas no significant differences in SBI except Group I and gingival recession(p<0.05). Membrane exposure levels were increased at 1, 2 and 6weeks postopratively compared to value of baseline in Group I(p<0.05). There were no statistically significant differences between ePTFE and PLGA membrane in probing depth, clinical attachment level and SBI. There were minimal gingival recession and membrane exposure in Group Ⅳ and pain and swelling were the most common postoperative complications in Group Ⅱ, Ⅲ(p<0.05). In conclusion, this study showed that both nonresorbable membrane and resorbable membrane were effective similarly in the treatment of class Ⅱ furcation defects, without statistical differences in clinical measurements.

• Journal of Periodontal and Implant Science
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• 제34권3호
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• pp.509-522
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• 2004

This study was performed to compare the clinical effectiveness of two regenerative techniques for class II furcation involvements in human: a combination of bone grafts with PRP vs. GTR with bone grafts. The e-PTFE group was treated with non-absorbable membrane and bone grafts, the PRP group was treated with PRP and bone grafts Pocket depth, clinical attachment level, and gingival recession were measured at baseline and postoperative 6 months. Vertical and horizontal furcation depth were measured by re-entry surgeries at 6 months post-treatment Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. The change of pocket depth, clinical attachment level, vertical furcation depth and horizontal furcation depth in both groups was decreased significantly at 6 months than at baseline. (p<0.05) 2. The change of gingival recession in both groups was increased significantly at 6 months than at baseline. (p<0.05) 3. The change of alveolar crest absorption in both groups was increased at 6 months than at baseline but there were no statistically significant differences. 4. The change of pocket depth, clinical attachment level, vertical furcation depth and horizontal furcation depth in both groups was increased significantly at 6 months, but there were no statistically or clinically significant differences with both groups. 5. The change of gingival recession and alveolar crest absorption in both groups was increased at 6 months, but there were no statistically or clinically significant differences with both groups. In conclusion, the use of bone graft with PRP or GTR technique improved clinical index of the soft and hard tissue in mandibular class II furcation involvement but there were no statistically or clinically significant differences between bone graft with PRP and GTR technique.

• Journal of Periodontal and Implant Science
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• 제50권6호
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• pp.358-367
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• 2020

Purpose: The aim of this study was to investigate the efficacy and validity of subgingival bacterial sampling using a retraction cord, and to evaluate how well this sampling method reflected changes in periodontal conditions after periodontal therapy. Methods: Based on clinical examinations, 87 subjects were divided into a healthy group (n=40) and a periodontitis group (n=47). Clinical measurements were obtained from all subjects including periodontal probing depth (PD), bleeding on probing (BOP), clinical attachment loss (CAL), and the plaque index. Saliva and gingival crevicular fluid (GCF) as a subgingival bacterial sample were sampled before and 3 months after periodontal therapy. The salivary and subgingival bacterial samples were analyzed by reverse-transcription polymerase chain reaction to quantify the following 11 periodontal pathogens: Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythus (Tf), Treponema denticola (Td), Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn), Pavimonas micra (Pm), Campylobacter rectus (Cr), Prevotella nigrescens (Pn), Eikenella corrodens (Ec), and Eubacterium nodatum (En). Results: Non-surgical periodontal therapy resulted in significant decreases in PD (P<0.01), CAL (P<0.01), and BOP (P<0.05) after 3 months. Four species (Pg, Tf, Pi, and Pm) were significantly more abundant in both types of samples in the periodontitis group than in the healthy group. After periodontal therapy, Cr was the only bacterium that showed a statistically significant decrease in saliva, whereas statistically significant decreases in Cr, Pg, and Pn were found in GCF. Conclusions: Salivary and subgingival bacterial sampling with a gingival retraction cord were found to be equivalent in terms of their accuracy for differentiating periodontitis, but GCF reflected changes in bacterial abundance after periodontal therapy more sensitively than saliva.

• Journal of Periodontal and Implant Science
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• 제40권1호
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• pp.33-38
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• 2010

Purpose: The purpose of this study was to observe and quantify the expression of interleukin-4 (IL-4), interferon-$\gamma$ (IFN-$\gamma$), and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in the gingival tissue of patients with type 2 diabetes mellitus (DM) and healthy adults with chronic periodontitis. Methods: Twelve patients with type 2 DM and chronic periodontitis (Group 3), twelve patients with chronic periodontitis (Group 2), and twelve healthy individuals (Group 1) were included in the study. Clinical criteria of gingival (sulcus bleeding index value, probing depths) and radiographic evidences of bone resorption were divided into three groups. The concentrations of cytokines were determined by a western blot analysis and compared using one-way ANOVA followed by Tukey's test. Results: The expression levels of IFN-$\gamma$ and TIMP-2 showed an increasing tendency in Groups 2 and 3 when compared to Group 1. On the other hand, the expression of IL-4 was highest in Group 1. Conclusions: The findings suggest that IFN-$\gamma$ and TIMP-2 may be involved in the periodontal inflammation associated with type 2 DM. IL-4 may be involved in the retrogression of the periodontal inflammation associated with type 2 DM.