• 대한조선학회 특별논문집
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• 대한조선학회 2009년도 특별논문집
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• pp.107-114
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• 2009

In the recent large block are used to build the ship to improve productivity. For this reason, two or more floating cranes that are connected in parallel is the trend. Typically, when working with floating crane load safety factor is considered. Even in the parallel operation, load safety factor is calculated similar to working alone. For this reason, operations do not guarantee the reliability or excessive safety factor applied. Therefore, the subdivided cases for calculating the safety factor are defined when parallel connected floating cranes are operated. Based on those cases, the operation standard is made about procedure using parallel connected floating cranes. And to verify this, dynamics simulation was performed for verification using the dynamics simulation program.

• 대한한방내과학회지
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• 제25권4호
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• pp.105-116
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• 2004

Objective : In this study, we used the aged bilateral common carotid artery occlusion (BCAO) rats were used to measure the effect of Bupleuri Radix (Si-Ho) on the brain ischemic injury, because aging is an important factor in storke, Method : The brian ischemic injury was induced by temporary closing of carotids on both sides in a low blood pressure state. Bupleuri Radix (Si-Ho) was orally administered in 18-month-old BCAO rats. Result : The Ischemic Damaged Hippocampus and HSP expression were analyzed by the immunohistochemical staining and the result were as follows: 1. The low numbers of pyramid cells in the hippocampus CA1 area for the ischemically injured experimental group rose to numbers simillar to those of the control group. 2. The thin neuronal cell layer in the hippocampus CA1 area for the ischemically injured experimental group returned to thickness simillar to those of the control group. 3. The normalized optical density of HSP70 expression was suppressed in CA2, DG and CA1 expression was significantly suppressed in the experimental group compared to the control group. Conclusion : These results suggested that Bupleuri Radix (Si-Ho) has a neuroprotective effect by reducing neural cell injury in the initial ischemic state.

• 생약학회지
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• 제43권4호
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• pp.316-322
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• 2012

Siegesbeckia Herba is known to have anti-oxidant, anti-inflammatory, anti-allergic and anti-tumor. The objective of this study is to explore the neuroprotective effect of Siegesbeckia Herba against glutamate-induced oxidative stress in mouse hippocampal HT22 cells. Siegesbeckia Herba 70% ethanol extract and solvent fractions have the potent neroprotective effects on glutamate-induced nerotoxicity by induced the expression of heme oxygenase (HO)-1 in the mouse hippocampal HT22 cells. Especially, ethyl acetate fraction showed higher protective effect. In HT22 cell, Siegesbeckia Herba ethyl acetate fraction makes the nuclear accumulation of Nrf2. Further, we found that treatment with c-JUN N-terminal kinase (JNK) inhibitor (SP600125) reduced Siegesbeckia Herba ethyl acetate fraction induced HO-1 expression and Siegesbeckia Herba ethyl acetate fraction also increased JNK phosphorylation. In conclusion, the ethyl acetate fraction of 70% ethanol extract of Siegesbeckia Herba significantly protect glutamate-induced oxidative damage by induction of HO-1 via Nrf2 and JNK pathway in mouse hippocampal HT22. Taken together these finding suggest that Siegesbeckia Herba ethyl acetate fraction good source for taking active compounds and may be a potential therapeutic for brain disorder by targeting the oxidative stress of neuronal cell.

• 한국자동차공학회논문집
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• 제16권5호
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• pp.147-156
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• 2008

As the management of fuel efficiency becomes globally reinforced in attempts to find an environment-friendly vehicle that will operate against global warming, the interest in and the demand for the type of vehicle with a high-efficiency diesel engine using light oil. However, it also emits a greater amount of PM (particulate matter) and NOx than emissions from vehicles using other types of fuels. Therefore, the DME (Dimethyl Ether), an oxygen containing fuel draws attention as an alternative fuel for light oil that can be used for diesel engines since it generates very little smoke. But to develop and compare performance of an electric controlled common-rail DME engine, engine tests requires optimized injection conditions at required engine RPM and engine torque. These injection conditions cannot be set freely and the data configuration through the experimentally repeated application requires much time as well as a significant amount of errors and effort. The object of this study is to configure the basic injection map using the results of the DME engine experiments performed so far. For this, in this study, the functionalization of the required equations were performed along with the basic review of the factors that had influence on the data map. Through this, the information on the injection pressure, injection amount, injection duration, injection timing, etc. under certain operation condition could be obtained.

• Toxicological Research
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• 제21권1호
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• pp.23-29
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• 2005

A developmental study of CONP01, a new antiarthritic agent, was conducted in Sprague-Dawley rats. Dosage of CONP01 0, 111, 333, and 1000 mg/kg/day were administered to dams orally from day 6 to day 16 of gestation. Two-third of dams per group were subjected to caesarean section on day day 20 of pregnancy for examination of their fetuses, and the remaining one-third of dams per group were allowed to deliver naturally for postnatal examination of their offspring. There was no change in the dams body weights, food consumptions, specific clinical sings and gross findings. There was significant decrease only in the absolute and relative weights of right ovary in 111 mg/kg treatment group, when compared with the vehicle control, whereas other organ weights were not changed. Moreover, no increase in the frequencies of external, visceral and skeletal malformation of fetuses were observed in the treated groups. These results suggest that the oral NOAEL (no observed adverse effect level) of CONP01 may be over 1,000 mg/kg in dams and fetuses of rats.

• Tuberculosis and Respiratory Diseases
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• 제45권3호
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• pp.624-629
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• 1998

기관내 삽관 후 발생한 기관협착환자의 치료는 아직 완전한 치료법이 정립되어 있지 않아 다양한 치료법들이 이용되고 있는 실정이며 경직성 기관지경이나 풍선도관을 이용한 물리적인 확장, 혹은 레이저시술 후 스텐트 삽입등이 수술적인 치료 전에 할 수 있는 치료법이다. 저자등은 레이저시술에 이은 풍선 도관으로 확장을 시행한 기관내 삽관 후 발생한 기관협착 1례를 문헌고찰과 함께 보고하는 바이다.

• 한국정밀공학회지
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• 제29권3호
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• pp.253-260
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• 2012

In nowadays, the infrared optics is frequently employed to various fields such as military, aerospace, industry and medical. To develop the infrared optics, special glasses which can transmit infrared wave are required. Ge(Germanium), Si(silicon), and fluoride glasses are typically used for material of the infrared optics. Compared with Ge and Si glasses, fluoride glasses have high transmittance in infrared wavelength range. Additionally, UV(ultraviolet) and visible light can be transmitted through fluoride glasses. There characteristics of fluoride glasses makes it possible to evaluate optical performance with generally used visible testing equipment. In this paper, we used design of experiment to find ultra precision machining characteristic of Ge and fluoride glasses and optimized machining process to obtain required form accuracy of PV(Peak to Valley) $0.2\;{\mu}m$.

• 대한수의학회지
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• 제36권1호
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• pp.1-9
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• 1996

Functional and morphological characteristics of the exocrine pancreas in genetic model BB rat of insulin dependent diabetes medllitus(IDDM) were carried out. Wistar rat was used as control animal. Flow rate of pancreatic juice, output of amylase and protein, and plasma glucose and insulin levess were examined. Also light and ultrastructural characteristics of the exocrine pancreas were observed. Pancreatic flow rate, output of amylase and protein, and insulin level were lower;glucose level was higher comparing with those of the control Wistar rat. In Wistar rat, exocrine pancreas was typical light microscopically. Zymogen granules and cell organelles were well developed in fine structure. Cell size of the periinsular acini was larger, and number of zymogen granules were more than those of the teleinsular acini. Most acinar cells were dark cells which containe well-developed RER in their cytoplasm. On the other hand, some light cells which have the dilated RER cisterns were found. In BB rat exocrine pancreas, cell size of per-and tele-insular acini similar to that of Wistar rat. The number of light cells occupied 40-50% compairing with that of Wistar rat. Zymogen granules were lower in number than that of Wistar rat and divied into three types in morphological characteristics ; type I showing normal structure, type II showing the wide hallo and small electron dense core in center of the zymogen granule and type III not having the electron dense core in the zymogen granule. The present ratio of type I, type II and type III are less than 5%, 30-40% and more than 50%, respectively.

• Nuclear Engineering and Technology
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• 제35권1호
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• pp.14-24
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• 2003

This work investigates the effects of Cr$_2$O$_3$ and oxygen potential on grain growth and densification of UO$_2$ pellets. Powder mixtures of UO$_2$ and 0.03-0.4wt% Cr$_2$O$_3$ were pressed and sintered in 3 different gas atmospheres: the $H_2O$-to-H$_2$ ratios were 5$\times$10$^{-4}$ , 1$\times$10$^{-2}$ and 3$\times$10$^{-2}$ In the first gas atmosphere the Cr$_2$O$_3$ contents below 0.2 wt% have an insignificant effect on grain size, but the Cr$_2$O$_3$ contents more than 0.3 wt% promote grain growth in the inner zone of a pellet but not in the outer zone. In both the second and third atmospheres, the grain size increases with the Cr$_2$O$_3$ content. With the same level of Cr$_2$O$_3$ content the grain size is larger in the second atmosphere than in the third. Sintering behavior and developed microstructure are discussed in terms of the reduction of C$r^2$O$^3$ to Cr, the dissolution of C$r^2$O$^3$ in UO$_2$, and liquid phase sintering.

• 전자공학회논문지S
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• 제36S권9호
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• pp.1-8
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• 1999

이 논문에서는 쇄상부호 직접수열 부호분할 다중접속 시스템을 제안하였다. 대역효율이 좋은 쌍직교 신호별자리를 쓰는 $2^{2L-2}$ 상태 ${\frac{L}{L+1}}$ 2차원 격자부호변조를 안쪽부호로 썼고 바깥부호로는 연집오류에 강한 $(2^{L-1},\;{\lceil}\frac{2^{L-1}}{L/2}{\rceil})$ 리드-솔로몬 부호를 썼다. 제안한 시스템의 성능을 분석하여 전송속도를 떨어뜨리지 않으면서 상당한 성능이득을 얻을 수 있다는 것을 보였다. 따라서, 제안한 방식은 무선통신 환경에서 빠르게 정보를 전송하면서도 높은 신뢰성을 가지는 부호화 방식으로 쓰일 수 있을 것이다.