• 제어로봇시스템학회논문지
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• 제13권5호
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• pp.444-451
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• 2007

In this paper, we propose an improved reduction model and a reduction model-based hybrid smith-predictor fuzzy controller. The transient and steady-state responsed of the reduction model was evaluated. In tuning the controller, the parameters of PID and the factors fuzzy controllers were obtained from the reduced model and by using genetic algorithms, respectively. Simulation examples demonstrated a better performance of the proposed controller than conventional ones.

• Clinical and Experimental Pediatrics
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• 제59권6호
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• pp.247-251
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• 2016

The pathophysiology and fundamental etiologic mechanism of inflammatory bowel disease (IBD) is not well understood even though therapeutic regimens and drugs are rapidly evolutionary. IBD has complicated connections with genetic, immunologic, gut microbial, environmental, and nutritional factors. It is not clearly well known to the physicians how to feed, what nutrients are more helpful, and what food to be avoided. This review discusses the issues of growth and important nutritional concerns in the management of IBD in childhood.

• 미생물과산업
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• 제19권4호
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• pp.14-26
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• 1993

Optimizing protein production in recombinant E. coli strains involves manipulation of genetic and environmental factors. In designing a production system, attention must be paid to gene expression efficiency, culture conditions and bioreactor configuration. Although not much emphasis was given to the physiology of host strains in this review, an understanding of the relationship between the physiology of host cell growth and the overproduction of a cloned gene protein is of primary importance to the improvement of the recombinant fermentation processes. Sometimes it is desirable to make use of gene fusion systems, e.g. protein A, polypeptide, gutathione-S-transferase, or pneumococcal murein hydrolase fusion, to facilitate protein purification.

• Genomics & Informatics
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• 제12권4호
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• pp.203-207
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• 2014

Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong and Ansan cohort data. About 300,000 single-nucleotide polymorphisms and 20 epidemiological variables were analyzed. We did not find any meaningful significant single nucleotide polymorphisms, but we confirmed the influence of major epidemiological variables on hepatitis.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.405-406
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• 2003

DNA is known as the genetic material in cells. Various environmental factors can cause DNA damages. One of them is sunlight. The life on earth depends on the sunlight, but on the other hand, the UV light in sunlight can cause skin DNA damages. When these damages are not fully repaired before replication, they can lead to mutations of oncogenes and tumour suppressor gene and result in photo carcinogenesis, in the end, skin cancer.(omitted)

• 대한임상약리학회:학술대회논문집
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• 대한임상약리학회 2002년도 제11차 추계학술대회
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• pp.7-7
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• 2002

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 D
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• pp.2702-2704
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• 2001

In this Letter, we propose a comprehensive design methodology of hybri'd Fuzzy controllers (HFC). The HFC comes as a form of a convex combination of a standard PID controller and a fuzzy controller. The design procedure dwells on the use of evolutionary computing (genetic algorithm) and an auto-tuning algorithm. The tuning of the scaling factors of the HFC is an essential component of the entire optimization process. A numerical study is presented and a detailed comparative analysis is also included.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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• pp.118-130
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• 2002

The frequency of prostate cancer has been increasing (1). Afflicting 10% of men older than the age of 65, it repre-sents the most frequently diagnosed cancer in American men, with an even higher incidence in the African-American population. Many investigators have tried to identify prognostic markers that distinguish indolent versus aggressive forms of prostate cancer, and to understand the genetic factors that evoke prostate cancer initiation and progression (2).(omitted)

• Childhood Kidney Diseases
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• 제23권2호
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• pp.86-92
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• 2019

Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for SRNS may lead to a better understanding of podocyte structure and function in the glomerular filtration barrier. This review focuses on genes associated with slit diaphragm, actin cytoskeleton, transcription factors, nucleus, glomerular basement membrane, mitochondria, and other proteins that affect podocyte biology.

• 한방비만학회지
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• 제19권2호
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• pp.119-136
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• 2019

Objectives: People often fail to maintain their weight even though they have succeeded in weight loss. The purpose of this study was to review previously published study results with regards to the predictive factors associated with weight loss maintenance after successful weight loss. Methods: The authors searched for the articles related to weight loss maintenance after successful weight loss, published up until June 2019 on PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, Research Information Sharing Service (RISS), and Koreanstudies Information Service System (KISS). A total of 76 articles were finally selected. From the study results, changeable and unchangeable predictors were extracted, and these predictors were examined according to detailed categories. Results: The changeable predictors of weight loss maintenance included behavioral factors, psychological factors and treatment process-related factors, whereas the unchangeable predictors included genetic and physiological factors, demographic factors, history of treatment on obesity-related factors. The main factors of weight loss maintenance were changeable predictors such as healthy eating habits, dietary intake control, binge eating control, regular exercise and physical activity, depression and stress control, social supports, self-regulation, self-weighing and initial weight loss and unchangeable predictors such as low initial weight and maximum lifetime weight. Conclusions: The results of our review results suggest that changeable and unchangeable predictors of weight loss maintenance should be carefully examined during treatments of obesity.