• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1145-1148
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• 2014

Background: Single pegylated liposomal doxorubicin (PLD) is commonly used as a salvage treatment in platinum-resistant ovarian cancer, fallopian tube cancer and primary peritoneal adenocarcinoma (PPA) with a satisfactory outcome. However, the data for second generation PLD administered in this setting are still limited. We conducted a retrospective study to evaluate the outcome of patients who received single-agent second generation PLD (LIPO-DOX) after the development of clinical platinum resistance. The study period was between March 2008 and March 2013. LIPO-DOX was administered intravenously 40 $mg/m^2$ every 28 days until disease progression, but for not more than six cycles. The response rate was evaluated using the Gynecologic Cancer Intergroup (GCIG) criteria while the toxicity was evaluated according to WHO criteria. Twenty-nine patients met the inclusion criteria in the study period with an overall response rate of 13.8%. The median progression free survival and overall survival were three and eleven months, respectively. With the total of 96 cycles of chemotherapy, the patients developed grades 3 and 4 hematologic toxicity as follows: anemia, 0%, leukopenia, 9.6%, neutropenia, 32.3% and thrombocytopenia, 0%. In conclusion, the single agent second generation PLD demonstrated modest efficacy in patients with platinum-resistant ovarian cancer, fallopian tube cancer and PPA without serious toxicity.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2001년도 춘계학술대회 논문집(한국공작기계학회)
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• pp.422-428
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• 2001

The term High Speed Machining has been used for many years to describe end milling with small diameter tools at high rotational speeds, typically 10,000 - 100,000 rpm. The process was applied in the aerospace industry for the machining of light alloys, notably aluminium. In recent year, however, the mold and die industry has begun to use the technology for the production of components, including those manufactured from hardened tool steels. With increasing cutting speed used in modern machining operation, the thermal aspects of cutting become more and more important. It not only directly influences in rate of tool wear, but also will affect machining precision recognized as thermal expansion and the roughness of the surface finish. Hence, one needs to accurately evaluate the rate of cutting heat generation and temperature distributions on the machining surface. To overcome the heat generation, we used to cutting fluid. Cutting fluid play a roles in metal cutting process. Mechanically coupled effectiveness of cutting fluids affect to friction coefficient at tool-work-piece interface and cutting temperature and chip control, surface finish, tool wear and form accuracy. Through this study, we examined the behavior of heat generation in high-speed machining and the cooling performance of various cooling methods.

• 전자공학회논문지C
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• 제36C권4호
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• pp.1-16
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• 1999

본 논문에서는 테스트 생성 과정에서 자주 사용되는 임계의 확장 개념으로 임계-쌍을 정의한다. 그리고 임계의 특성을 나타내는 요소로서 임계성, 임계율, 임계설정율 등을 정의한다. 이 요소들을 이용하여 임계-쌍의 사용이 단일 임계의 사용보다 더 효율적이라는 것을 입증하고, FFR에서의 테스트 패턴 생성 시에 임계값에 대한 평가 회수, 경로선의 탐색 회수 및 생성 시간에서 더 효율적이라는 것을 보여준다. 시뮬레이션을 통해서 ISCAS85 벤치마크 테스트 회로에 대한 실험 결과를 비교 분석한다.

• Journal of Communications and Networks
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• 제6권3호
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• pp.245-257
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• 2004

Driven by the growing number of the mobile subscribers, efficient channel resource management plays a key role for provisioning multimedia service in the next generation personal communication systems. To reuse limited channel resources, diminishing the coverage areas of cells seems to be the ultimate solution. Thus, however, causes more handover events. To provide seamless connection environment for mobile terminals and applications, this article presents a novel handover scheme called the intelligent channel reservation (ICR) scheme, which exploits the location prediction technologies to accurately reserve channel resources for handover connections. Considering the fact that each mobile terminal has its individual mobility characteristic, the ICR scheme utilizes a channel reserving notification procedure (CRNP) to collect adequate parameters for predicting the future location of individual mobile terminals. These parameters will be utilized by the handover prediction function to estimate the expected handover blocking rate and the expected number of idle channels. Based on the handover prediction estimations, a cost function for calculating the damages from blocking the handover connections and idling channel resources, and a corresponding algorithm for minimizing the cost function are proposed. In addition, a guard channel decision maker (GCDM) determines the appropriate number of guard channels. The experimental results show that the ICR scheme does reduce the handover-blocking rate while keeping the number of idle channels small.

• International Journal of Fluid Machinery and Systems
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• 제10권1호
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• pp.19-29
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• 2017

An objective of this study is to demonstrate the validity of using a small wind turbine to recover the fluid energy flowing out of an exhaust duct for the generation of power. In these experiments, a butterfly wind turbine of a vertical axis type (D = 0.4 m) is used. The output performance is measured at various locations relative to the exit of a small wind tunnel (W = 0.65 m), representing the performance expected in an exhaust duct flow. Two-dimensional numerical analysis qualitatively agrees with the experimental results for the wind turbine power coefficient and rate of energy recovery. When the turbine is far from the duct exit (more than 2.5 D), an energy recovery rate of approximately 1.3% is obtained.

• 환경위생공학
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• 제13권3호
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• pp.9-18
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• 1998

An experimental research was conducted to establish primary data for the stabilization assessment of industrial wastes landfill with analysis of waste components and investigation of leachate and gas generation, using three sets of lysimeter as experimental apparatus. Comparing results of lysimeter from data of landfill, it is suggested that lysimeter of this study can be used to accomplish the stabilization assessment of the real landfill site. Moisture content was lower as landfill period was older and combustible component was the highest in lysimeter C. The C/N ratio of waste was 7.4~14.4 and, with the elemental analysis, the theoretical gas generation rate based on the modified Buswell equation was 0.47~0.49 $m^3/kg-dry$ waste in lysimeter C. Considering the C/N ratio of leachate, it is concluded that the addition of carbon source is needed to biodegrade leachate hereafter. Gas generation rate($m^3/kg-dry$ waste) from lysimeter A, B and C was 0.0009, 0.014 and 0.0067, respectively, and different from each other according to the landfill period of wastes. The results in this study show that the biodegradation of microorganism for stabilization of landfill was inhibited and more activated in acidogenic step than in methanogenic of anaerobic degradation.

• 조명전기설비학회논문지
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• 제22권1호
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• pp.149-156
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• 2008

최근 오존은 그 활용성을 인정받아 다양한 분야에서 사용되고 있으며, 그 수요 또한 계속 증가하는 추세이다. 이에 다양한 종류의 오존발생기가 연구되고 있으며, 고농도 및 고수율을 얻는 것이 연구목표라 할 수 있다. 본 논문에서는 전극 형태에 따른 평판형 오존발생기를 제작하여 원료가스의 유량 및 방전전력의 변화에 의한 오존생성농도, 오존생성량 및 오존생성수율 특성을 연구하였다.

• 한국정밀공학회지
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• 제18권1호
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• pp.82-88
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• 2001

The demands of high data transfer rate and high recording density in optical disk memory device are being increased. In this paper, 4 design parameters for next generation optical disk are investigated. As for the high data transfer rate, two design parameters such as driving acceleration and transmissibility are introduced. As the high recording density is concerned, the minimum linearity and the tilt of the actuator are introduced. Two kinds of pickup actuator are used to evaluate the validity of the parameters through the simulation and the experiment. The 4-wire actuator has good linearity but bad stability and tilt characteristics, while the rotary and axis actuator has good stability for the external vibration but bad linearity. It is demonstrated that the newly proposed design parameters are available to design and evaluate quantitatively the performance of the actuator for the next generation optical disk.

• 패션비즈니스
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• 제19권2호
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• pp.1-22
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• 2015

This study provides the basic data for clothing construction of teen girls by researching and analyzing the characteristics of physical changes of tween generation school girls between 8 to 14 age. Fifty eight items of direct measurements and 61 calculated-items based on the 6th Korean National Physical Standard Reports were used. Results were obtained by using ANOVA, SNK test, coefficient of variation and growth rate of age groups. Significant differences were found among all the age groups, and were in the increasing order of height > length > width > depth > circumference. The growth rate was found in the increasing order of bust depth > hip width > N.P. to B.P. > hip circumference > bust circumference and thigh circumference. There were dramatic increases in height, circumference and width during the age of 8~9 and 10~11, in length during age of 10~11, and in depth during age of 8~11. The growth of the vertical measurement items is slowing at the age of 13. The individual differences were great in the vertical measurements at the age of 8 and 9 and in the horizontal measurements, at the age of 10. The increasing growth of bust and hip than waist gave it a curved shape.

• Journal of Information Processing Systems
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• 제10권2호
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• pp.314-333
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• 2014

When analyzing default predictions in real estate companies, the number of non-defaulted cases always greatly exceeds the defaulted ones, which creates the two-class imbalance problem. This lowers the ability of prediction models to distinguish the default sample. In order to avoid this sample selection bias and to improve the prediction model, this paper applies a minority sample generation approach to create new minority samples. The logistic regression, support vector machine (SVM) classification, and neural network (NN) classification use an imbalanced dataset. They were used as benchmarks with a single prediction model that used a balanced dataset corrected by the minority samples generation approach. Instead of using prediction-oriented tests and the overall accuracy, the true positive rate (TPR), the true negative rate (TNR), G-mean, and F-score are used to measure the performance of default prediction models for imbalanced dataset. In this paper, we describe an empirical experiment that used a sampling of 14 default and 315 non-default listed real estate companies in China and report that most results using single prediction models with a balanced dataset generated better results than an imbalanced dataset.