• Proceedings of the IEEK Conference
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• 2003.11c
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• pp.105-108
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• 2003

In the next generation backbone networks based on dense-wavelength division multiplexing (DWDM), the routing and wavelength assignment with quality-of-service (QoS) recovery is essentially needed to support a wide range of communication-intensive and real-time multimedia services. This paper proposes a new dpmic routing method called as MW-MIPR (MultiWavelength-Minimum Interference Path Routing), which chooses a route that does not interfere too much with many potential future connection requests. This paper also proposes a differentiated RWA mechanisms combined with MW-MIPR algorithm to provide QoS recovery for various multimedia applications in the next generation backbone networks based on DWDM.

• Journal of KIISE
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• v.44 no.7
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• pp.674-679
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• 2017

In big-data environments wherein large amounts of text documents are produced daily, titles are very important clues that enable a prompt catching of the key ideas in documents; however, titles are absent for numerous document types such as blog articles and social-media messages. In this paper, a title-generation model for which sequence-to-sequence RNNs with attention and copying mechanisms are employed is proposed. For the proposed model, input sentences are encoded based on bi-directional GRU (gated recurrent unit) networks, and the title words are generated through a decoding of the encoded sentences with keywords that are automatically selected from the input sentences. Regarding the experiments with 93631 training-data documents and 500 test-data documents, the attention-mechanism performances are more effective (ROUGE-1: 0.1935, ROUGE-2: 0.0364, ROUGE-L: 0.1555) than those of the copying mechanism; in addition, the qualitative-evaluation radiative performance of the former is higher.

• Korean Journal of Agricultural Science
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• v.43 no.1
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• pp.72-79
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• 2016

It has long been known that nutritional and environmental influences during the early developmental period affect the biological mechanisms which determine animal metabolism. This phenomenon, termed 'metabolic imprinting', can cause subtle but long-lasting responses to prenatal and postnatal nutrition and even be passed onto the next generation. A large amount of research data shows that nutrient availability, in terms of quantity as well as quality, during the early developing stages can decrease the number of newborn piglets and their body weight and increase their susceptibility to death before weaning. However, investigation of potential mechanisms of 'the metabolic imprinting' effect have been scant. Therefore, it remains unknown which factors are responsible for embryonic and early postnatal nutrition and which factors are major determinants of body weight and number of new born piglets. Intrauterine undernutrition, for example, was studied using a rat model providing dams 50% restricted nutrients during pregnancy and the results showed significant decreases in birth weight of newborns. This response may be a characteristic of a subset of modulations in embryonic development which is caused by the metabolic imprinting. Underlying mechanisms of intrauterine undernutrition and growth retardation can be explained in part by epigenetics. Epigenetics modulate animal phenotypes without changes in DNA sequences. Epigenetic modifications include DNA methylation, chromatin modification and small non-coding RNA-associated gene silencing. Precise mechanisms must be identified at the morphologic, cellular, and molecular levels by using interdisciplinary nutrigenomics approaches to increase pig production. Experimental approaches for explaining these potential mechanisms will be discussed in this review.

• International Journal of Oral Biology
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• v.48 no.4
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• pp.33-44
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• 2023

In this review, the regulatory mechanisms of autophagy were described, and its interaction with apoptosis was identified. The role of autophagy in embryogenesis, tooth development, and cell differentiation were also investigated. Autophagy is regulated by various autophagy-related genes and those related to stress response. Highly active autophagy occurrences have been reported during cell differentiation before implantation after fertilization. Autophagy is involved in energy generation and supplies nutrients during early birth, essential to compensate for their deficient supply from the placenta. The contribution of autophagy during tooth development, such as the shape of the crown and root formation, ivory, and homeostasis in cells, was also observed. Genes control autophagy, and studying the role of autophagy in cell differentiation and development was useful for understanding human aging, illness, and health. In the future, the role of specific mechanisms in the development and differentiation of autophagy may increase the understanding of the pathological mechanisms of disease and development processes and is expected to reduce the treatment of various diseases by modulating the autophagic phenomenon.

• Radiation Oncology Journal
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• v.32 no.3
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• pp.103-115
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• 2014

To summarize current knowledge regarding mechanisms of radiation-induced normal tissue injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity-modulated radiation therapy have permitted delivery of higher doses of radiation to well-defined tumor target tissues. Injury to critical normal tissues and organs, however, poses substantial risks in the curative treatment of cancers, especially when radiation is administered in combination with chemotherapy. The principal pathogenesis is initiated by depletion of tissue stem cells and progenitor cells and damage to vascular endothelial microvessels. Emerging concepts of radiation-induced normal tissue toxicity suggest that the recovery and repopulation of stromal stem cells remain chronically impaired by long-lived free radicals, reactive oxygen species, and pro-inflammatory cytokines/chemokines resulting in progressive damage after radiation exposure. Better understanding the mechanisms mediating interactions among excessive generation of reactive oxygen species, production of pro-inflammatory cytokines and activated macrophages, and role of bone marrow-derived progenitor and stem cells may provide novel insight on the pathogenesis of radiation-induced injury of tissues. Further understanding the molecular signaling pathways of cytokines and chemokines would reveal novel targets for protecting or mitigating radiation injury of tissues and organs.

• Clinical and Experimental Pediatrics
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• v.50 no.12
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• pp.1165-1172
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• 2007

Self/non-self discrimination and unresponsiveness to self is the fundamental properties of the immune system. Self-tolerance is a state in which the individual is incapable of developing an immune response to an individual's own antigens and it underlies the ability to remain tolerant of individual's own tissue components. Several mechanisms have been postulated to explain the tolerant state. They can be broadly classified into two groups: central tolerance and peripheral tolerance. Several mechanisms exist, some of which are shared between T cells and B cells. In central tolerance, the recognition of self-antigen by lymphocytes in bone marrow or thymus during development is required, resulting in receptor editing (revision), clonal deletion, anergy or generation of regulatory T cells. Not all self-reactive B or T cells are centrally purged from the repertoire. Additional mechanisms of peripheral tolerance are required, such as anergy, suppression, deletion or clonal ignorance. Tolerance is antigen specific. Generating and maintaining the self-tolerance for T cells and B cells are complex. Failure of self-tolerance results in immune responses against self-antigens. Such reactions are called autoimmunity and may give rise to autoimmune diseases. Development of autoimmune disease is affected by properties of the genes of the individual and the environment, both infectious and non-infectious. The host's genes affect its susceptibility to autoimmunity and the environmental factors promote the activation of self-reactive lymphocytes, developing the autoimmunity. The changes in participating antigens (epitope spreading), cells, cytokines or other inflammatory mediators contribute to the progress from initial activation to a chronic state of autoimmune diseases.

• The Korean Journal of Food & Health Convergence
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• v.10 no.3
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• pp.1-8
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• 2024

The global nutraceuticals market continues to grow due to rising income levels, increasing life expectancy, and a growing interest in personal health. Especially after the COVID-19 pandemic, the market for nutraceuticals has expanded rapidly with positive perceptions driven by increased attention to immune management for disease prevention. However, there is still a lack of research on the relationship between nutraceuticals and consumer behavior. This study aims to provide new insights into the dietary supplement market and help establish marketing strategies by analyzing consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. An online survey was conducted among consumers who have purchased dietary supplement products to test the hypotheses. The collected data were analyzed for validity and reliability using SPSS and AMOS programs. The results showed that the taste, price, brand, and design of dietary supplements significantly positively affect the satisfaction of MZ consumers. This study provides an in-depth understanding of the mechanisms of consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. By offering insights into consumers' health concerns and consumption behaviors, this study provides valuable perspectives on the future development of the market and helps companies develop effective strategies to meet consumer needs.

• Korean Journal of Organic Agriculture
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• v.20 no.4
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• pp.447-458
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• 2012

This study was carried out to evaluation of biomass generation mechanisms and to propose the estimation method of biomass generation. Agricultural by-product biomass is generated during crops cultivation and after harvest. However these are not uniformly generated yearly and these depending on the seasons. For planning of biomass utilization, accurate information of the biomass resources is needed, especially characteristic and productivity of biomass are necessary. Agricultural by-product biomass are generated in a wide area being scattered and it is one of the major reason why agricultural biomass utilization is not activated compared with other waste biomass. In this study, estimation and evaluation biomass generation is achieved in specific spatial and temporal boundary, A-city in Gyeongi-do and september to November respectively. Quantity and quality of by-product biomass show big difference depending on the crop species and cultivation periods and these difference bring up that accurate biomass estimation should be considered during planning of biomass utilization and technology selecting for biomass converting to energy and other forms.

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2005.11a
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• pp.339-342
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• 2005

In order to support ultrawide-band signal generation for low rate WPAN, several types of signal generation mechanisms are suggested such as Chaos, Impluse, and Chirp signals by the activity of IEEE 802.15.4a. The communication system applied chaos theory may have ultrawide-band characteristics with spread spectrum and immunity from multipath effect. In order to use the advantage of chaotic signal generation, we introduce the system implementation of communication and networking systems with the chaos UWB signal. This system may be composed of mainly three parts in hardware architecture : RF transmission with chaotic signal generation, signal receiver using amplifiers and filters, and 8051 & FPGA unit. The most difficult part is to implement the chaotic signal generator and build transceiver with it. The implementation of the system is devidced into two parts i.e. RF blocks and digital blocks with amplifiers, filters, ADC, 8051 processor, and FPGA. In this paper, we introduce the system block diagram for chaotic communications. Mainly the RF block is important for the system to have good performance based on the chaotic signal generator. And the main control board functions for controlling RF blocks, processing Tx and Rx data, and networking in MAC layer.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.5
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• pp.985-991
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• 2009

A grammar-based test case generation (GBTG) algorithm takes a grammar G and generates a subset of the language L(G) accepted by G, and called test cases for software product testing. As most languages specified with CFG are recursive, usually L(G) is so large that it is not practical to execute all the of the generated cases. Therefore, this paper presents some "tags" : extra-grammatical annotations which are designed to restrict the generation. A number of control mechanisms have been developed to prune the number of test cases generated while still producing a test set that covers the majority of inputs to the system.