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Dexamethasone treatment for bilateral lingual nerve injury following orotracheal intubation

  • Kim, Saeyoung;Chung, Seung-Yeon;Youn, Si-Jeong;Jeon, Younghoon
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.18 no.2
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    • pp.115-117
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    • 2018
  • Lingual nerve injury is a rare complication of general anesthesia. The causes of lingual nerve injury following general anesthesia are multifactorial; possible mechanisms may include difficult laryngoscopy, prolonged anterior mandibular displacement, improper placement of the oropharyngeal airway, macroglossia and tongue compression. In this report, we have described a case of bilateral lingual nerve injury that was associated with orotracheal intubation for open reduction and internal fixation of the left distal radius fracture in a 61-year-old woman. In this case, early treatment with dexamethasone effectively aided the recovery of the injured lingual nerve.

The Study of 5,10-Methylenetetrahydrofolate Reductase Variation (MTHFR C677T) in Infertile Females with Polycystic Ovarian Syndrome (PCOS) in Korea (한국인 다낭성 난포증후군 환자에서 5,10-Methylenetetrahydrofolate Reductase의 677번 유전자 다형성에 관한 연구)

  • Lee, Kyo-Won;Jeong, Yu-Mi;Lee, Sook-Hwan;Yoon, Tae-Ki;Kwak, In-Pyung;Yoon, Seon-Woong;Choi, Joong-Sub;Kim, Kye-Hyun;Han, Jong-Sul;Kim, Sung-Do;Kim, Nam-Keun;Cha, Kwang-Yul;Baek, Kwang-Hyun;Lee, Su-Man
    • Clinical and Experimental Reproductive Medicine
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    • v.30 no.3
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    • pp.217-222
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    • 2003
  • Objective: To investigate the association of genetic background between MTHFR C677T genotype and infertile females with polycystic ovarian syndrome. Materials and Methods: We compared 86 infertile females with polycystic ovarian syndrome (PCOS) with 100 healthy fertile females with one or more offspring. Pyrosequencing analysis for MTHFR C677T variation was performed on polymerase chain reaction (PCR) product of study group. To validate pyrosequencing data of C677T variation for randomly selected 50 samples, we compared the pyrosequencing result with the PCR-RFLP (Restriction Fragment Length Polymorphism) result of MTHFR C677T genotype. Results: The prevalence of the C677T mutant homozygous (TT) was significantly lower (p=0.0085) in females with PCOS (8.14%) than in fertile females (21.00%). MTHFR 677 TT genotype had a decreased risk (3.7-fold) of PCOS compared with wild type (MTHFR 677 CC). Conclusion: Our data support a role for MTHFR mutant homozygous (677 TT) genotype in reducing risk in Korean infertile females with Polycystic ovarian syndrome.

Survey of medicinal plants in the Khuvsgul and Khangai Mountain regions of Mongolia

  • Magsar, Urgamal;Nyamsuren, Kherlenchimeg;Khadbaatar, Solongo;Tovuudorj, Munkh-Erdene;Baasansuren, Erdenetuya;Indree, Tuvshintogtokh;Lkhagvadorj, Khureltsetseg;Kwon, Ohseok
    • Journal of Ecology and Environment
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    • v.41 no.4
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    • pp.120-124
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    • 2017
  • We report the species of medicinal plants collected in Khuvsgul and Khangai Mountain regions of Mongolia. Of the vascular plants that occur in the study region, a total of 280 medicinal plant species belonging to 164 genera from 51 families are reported. Of these, we collected voucher specimen for 123 species between June and August in the years 2015 and 2016. The families Asteraceae (46 species), Fabaceae (37 species), and Ranunculaceae (37 species) were represented most in the study area, while Astragalus (21 species), Taraxacum (20 species), and Potentilla (17 species) were the most common genera found.

Web-based Collaborative Process Planning System for the Automotive General Assembly Shop (자동차 조립 공정계획을 위한 Web 기반 협업시스템)

  • Noh, Sang-Do;Park, Young-Jin;Kong, Sang-Hoon;Lee, Kyo-Il
    • IE interfaces
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    • v.16 no.3
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    • pp.375-381
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    • 2003
  • To ensure competitiveness in the modern automotive market, process planning should be performed concurrently with new car developments. In automotive general assembly shops, thus, new business workflows and supporting environments are inevitable to reduce the manufacturing preparation time in developing a new car in the manner of concurrent and collaborative engineering. Since complete process planning for a whole general assembly system is a huge and complex job, several process planners should execute their planning jobs and share information. Therefore, each planner should provide others with his/her results with continuous on-line communication and cooperation. In this research, a web-based system for concurrent and collaborative process planning for automotive general assembly is developed. By using this system, savings in time and cost of assembly process planning are possible, and the reliability of the planning result is improved.

The Status of Comprehensive Dental Treatment and Type of Disabilities of the Patients Treated under Outpatient General Anesthesia at the Clinic for the Disabled in Seoul National University Dental Hospital (서울대학교치과병원 장애인진료실에서 전신마취 하 치과치료를 받은 환자의 장애 질환 및 협진 현황 조사)

  • Jang, Ki-Taeg;Kim, Hyun-Jeong;Yum, Kwang-Won;Seo, Kwang-Suk
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.6 no.2 s.11
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    • pp.82-88
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    • 2006
  • Background: The number of patients with disabilities who require general anesthesia for dental treatment is increasing. Methods: We reviewed the cases of 538 patients with disabilities who underwent outpatient general anesthesia for dental treatment at the clinic for the disabled in Seoul national university dental hospital according to the types of disabilities and comprehensive treatments. Results: The patients mean age was 17.4 years and fifty-eight percent of the patients had epilepsy, autism, mental retardation and cerebral palsy. About twenty-five percent of the patients were medically compromised such as brain disease, heart disease and genetic problem. In 142 cases, more than two dentists from the clinical departments systemically co-worked to provide the patients with comprehensive treatment as accurately and quickly as possible under general anesthesia. Conclusions: The number of medically compromised patients was high and the system of comprehensive dental treatment was well run.

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A Study on the Teaching and Learning Method in General Lecture Class (일반강의식 수업에서 교수·학습 방법에 관한 연구)

  • Jang, Cheong Hee;Seo, Jong Jin
    • Journal of the Korean School Mathematics Society
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    • v.24 no.3
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    • pp.309-324
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    • 2021
  • From the past to the present, general mathematics classes have pursued changes in the educational environment. However, due to the actual college education conditions, general lecture classes are taking place. In this study, we wanted to find teaching and learning methods that would help students in general lecture classes. As a result, one group that took notes about class content and provided feedback on individual tasks was more effective in math achievement than the group that provided feedback on the same task. In addition, one group who took notes on class content and provided feedback on individual assignments was more effective in math achievement than the group who took notes on class content and provided feedback on the same task.

Clinical Analysis of MALT Lymphoma in the Stomach (위장의 점막 연관성 림프조직 림프종(MALT Lymphoma)의 임상적 고찰)

  • Paik Kwang Yeol;Noh Jae Hyung;Heo Jin Seok;Sohn Tae Sung;Choi Seong Ho;Joh Jae Won;Kim Yong-Il
    • Journal of Gastric Cancer
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    • v.1 no.1
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    • pp.60-63
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    • 2001
  • Purpose: The aim of this study was to analyze the clinical and the histopathological characteristics of mucosa associated lymphoid tissue (MALT) lymphomas in the stomach. Materials and Methods: We retrospectively reviewed the medical records of 22 patients who had been treated at Samsung Medical Center from Jan. 1995 to Sep. 2000 and who had been pathologically proven to have a MALT lymphoma. The factors we analyzed were operative procedure, tumor stage, and histopathological characteristics. Results: Of 3658 patients with a gastric malignancy, 22 patients proved to have a MALT lymphoma ($0.6\%$). There were 7 men and 15 women whose ages ranged from 25 years to 70 years (mean, 48.8 years). Forteen cases were located in the antrum, 4 ($18\%$) in the body and 4 ($18\%$) in the fundus or the high body. Nineteen of these patients were managed with total gastrectomy and splenectomy and 3 with radical subtotal gastrectomy. Histopathologically the tumor was limited to the mucosa in 3 patients ($1.36\%$), to the submucosa in 13 ($59.1\%$) and extended to the muscularis propria in 6 ($27.3\%$). Lymph node involvement was seen in 12 patients ($54.6\%$). There was no splenic or hepatic involvement. Bone marrow involvement was not seen in any patients. H. pylori was identified in 11 patients (50$\%$). During the mean follow-up period of 32.7 months, there were no reports of tumor recurrence or death. Conclusion: MALT lymphomas rarely disseminate by the time of diagnosis and rarely involve the bone marrow. Lymph node involvement is relatively high and a total gastrectomy is effective in managing patients with a MALT lymphoma.

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HIDE, a Testis Specific Deubiquitinating Enzyme, Interacts with HSP90 (고환 특이적으로 발현되는 탈유비퀴틴효소 HIDE와 HSP90의 상호작용)

  • Seong, Minu;Kim, Myung-Sun;Kim, Yong-Soo;Lee, Sook-Hwan;Lee, Hey-Jin;Cha, Kwang Yul;Baek, Kwang-Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.3
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    • pp.231-242
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    • 2005
  • 연구목적: 본 연구는 아직 그 기능이 파악되지 않은 탈유비퀴틴효소 중 하나인 HIDE에 대한 기본적인 생화학적 특징과 고환에서의 발현 양상을 파악하고 있다. 연구재료 및 방법: 인간의 HIDE 유전자를 클로닝하여 효소활성이 있는지 세포 외 실험을 통해 확인하였고, 아미노산 서열을 분석하여 진화상 보존된 부분을 찾아 그 기능을 파악한 다음 HSP90과의 상호작용을 공동면역침전반응으로 확인하였다. HIDE의 조직별 발현양상을 파악하기 위해서 인간과 쥐의 RNA 블롯과 쥐의 단백질 블롯을 이용하여 각각 노던 블롯팅과 웨스턴 블롯팅을 수행하여 고환에서 많이 발현된다는 것을 알았고 이 사실을 바탕으로 쥐의 고환을 절개하여 면역조직화학반응으로써 고환 내의 HIDE 단백질의 발현양상을 파악하였다. 결 과: HIDE는 세포 외에서 유비퀴틴 잔기를 제거하는 탈유비퀴틴 활성이 있으나 세포 내에서 전체적인 유비퀴틴 복합체를 줄여주는 효과는 없었다. HIDE는 HSP90이라는 분자 샤페론과 상호작용한다. HIDE의 전사체는 고환에서 가장 많이 발현되며 다른 조직에서도 소량 발현된다. HIDE의 단백질은 웨스턴 블롯상에서 고환에서만 확인되었다. 고환 내에서의 HIDE의 발현양상은 왕성한 감수분열을 하는 정모세포에서 높았으며 지지세포나 정조세포에는 발현되지 않았다. 결 론: HIDE는 분자 샤페론 HSP90과 상호작용하며 고환 내의 감수분열 중인 세포에서 많이 발현되는 것으로 보아 감수분열이나 정자형성에 관여하는 것으로 보인다.

Errors in light-emitting diodes positioning when curing bulk fill and incremental composites: impact on properties after aging

  • Abdulrahman A. Balhaddad;Isadora M. Garcia;Haifa Maktabi;Maria Salem Ibrahim;Qoot Alkhubaizi;Howard Strassler;Fabricio M. Collares;Mary Anne S. Melo
    • Restorative Dentistry and Endodontics
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    • v.46 no.4
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    • pp.51.1-51.13
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    • 2021
  • Objectives: This study aimed to evaluate the effect of improper positioning single-peak and multi-peak lights on color change, microhardness of bottom and top, and surface topography of bulk fill and incremental composites after artificial aging for 1 year. Materials and Methods: Bulk fill and incremental composites were cured using multi-peak and single-peak light-emitting diode (LED) following 4 clinical conditions: (1) optimal condition (no angulation or tip displacement), (2) tip-displacement (2 mm), (3) slight tip angulation (α = 20°) and (4) moderate tip angulation (α = 35°). After 1-year of water aging, the specimens were analyzed for color changes (ΔE), Vickers hardness, surface topography (Ra, Rt, and Rv), and scanning electron microscopy. Results: For samples cured by single-peak LED, the improper positioning significantly increases the color change compared to the optimal position regardless of the type of composite (p < 0.001). For multi-peak LED, the type of resin composite and the curing condition displayed a significant effect on ΔE (p < 0.001). For both LEDs, the Vickers hardness and bottom/top ratio of Vickers hardness were affected by the type of composite and the curing condition (p < 0.01). Conclusions: The bulk fill composite presented greater resistance to wear, higher color stability, and better microhardness than the incremental composite when subjected to improper curing. The multi-peak LED improves curing under improper conditions compared to single-peak LED. Prevention of errors when curing composites requires the attention of all personnel involved in the patient's care once the clinical relevance of the appropriate polymerization reflects on reliable long-term outcomes.