• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6109-6114
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• 2013

Aim: To determine whether beta-blockers (BBs) improve the overall survival (OS) of patients with metastatic non-small cell lung cancer (NSCLC). Materials and Methods: The medical charts of 107 patients with metastatic NSCLC were retrospectively assessed. Thirty-five patients (BB group) using BBs during chemotherapy (CT) were compared with 72 controls [control=(C) group] who did not use BBs following the diagnosis of NSCLC. The histological tumor subtype, performance status (ECOG), age, gender, smoking status, comorbidities, other medications and chemotherapeutics that were received in any line of treatment were recorded. We compared the overall survival (OS) of the patients in the BB and C groups. Results: The mean age of the patients was 61 years (range 42-81 years) and all patients were administered CT. The BB group was more likely to have HT and IHD and was more likely to use RAS blockers (p<0.01 for all) compared with the C group, as expected. The mean follow-up time was 17.8 months (range 1-102 months) for the entire group. The most commonly prescribed BB agent was metoprolol (80% of cases). At the time of the analysis, 74 (69%) of all patients had died. In the univariate analysis the median overall survival (OS) was 19.25 (${\pm}2.87$) months (95%CI: 13.62-24.88) in the BB group and 13.20 (${\pm}2.37$) months (95%CI: 8.55-17.85) in the C group (p=0.017). However, the benefit of BBs on survival disappeared in the multivariate analysis. Conclusions: The use of BBs during CT may be associated with an improved OS for patients with metastatic NSCLC.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.119-123
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• 2016

Thyroid cancer, the most common endocrine neoplasia, consists of four main types of carcinomas: papillary, follicular, and anaplastic, all with thyroid follicular origin, and medullary thyroid cancer (MTC) related to para-follicular cells. Cronic diseases such as diverse cancers may be associated with cachexia, especially at advanced stage. Cancer-induced cachexia is associated with diminished quality of life, functional performance, reduced response to antitumor therapy, and increased morbidity and mortality. Myostatin (Mst) is one of the outstanding molecules in the skeletal muscle loss process in cancer and it may be released by both skeletal muscle and cachexia-inducing tumors. Recently changes in serum levels of Mst have been identified as an important factor of cancer-induced cachexia. The goal of this study was to assessserum Mst levels in MTC patients. In this descriptive and case-control study, 90 participants were selected, comprising 45 MTC patients (20 males, $29{\pm}13.9years$, 25 females, $29{\pm}14.5years$) and 45 control individuals (25 males, $23.1{\pm}11.6years$, 20 females, $31.5{\pm}14.4years$). Serum Mst was determined using an ELISA kit and body mass index (BMI) was calculated by weight and height measurements. The Kolmogorov Simonov test showed a normal distribution for log transformed Mst serum levels in both case and control groups. Geometric means were 5.9 and 8.2 ng/ml respectively, and a significant difference was found according to the independent t-test results (P<0.01). There was also a significant difference mean of Mst between females in control and MTC groups, but not for the males. Pearson correlation test showed no correlation between age and BMI with Mst serum levels. The findings of this study support the hypothesis that Mst serum levels may have a potential ability for early diagnosis of cachexia in MTC patients, especially in females.

• Asian-Australasian Journal of Animal Sciences
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• 제27권6호
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• pp.767-777
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• 2014

Characterizing local chicken types and their mostly rural production systems is prerequisite for designing and implementing development and conservation programs. This study evaluated the management practices of small-scale chicken keepers and the phenotypic and production traits of their chickens in Oman, where conservation programs for local livestock breeds have currently started. Free-range scavenging was the dominant production system, and logistic regression analysis showed that socio-economic factors such as training in poultry keeping, household income, income from farming and gender of chicken owners influenced feeding, housing, and health care practices (p<0.05). A large variation in plumage and shank colors, comb types and other phenotypic traits within and between Omani chicken populations were observed. Male and female body weight differed (p<0.05), being $1.3{\pm}0.65$ kg and $1.1{\pm}0.86$ kg respectively. Flock size averaged $22{\pm}7.7$ birds per household with 4.8 hens per cock. Clutch size was $12.3{\pm}2.85$ and annual production $64.5{\pm}2.85$ eggs per hen. Egg hatchability averaged $88{\pm}6.0%$ and annual chicken mortality across all age and sex categories was $16{\pm}1.4%$. The strong involvement of women in chicken keeping makes them key stakeholders in future development and conservation programs, but the latter should be preceded by a comprehensive study of the genetic diversity of the Omani chicken populations.

• 대한간호학회지
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• 제41권1호
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• pp.119-128
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• 2011

Purpose: This study was done to determine the risk factors for recurrent fallers (2+falls) compared to single fallers. Methods: Participants were 104 community-dwelling people 65 yr of age or older. The data were collected from June 1, 2008 to June 30, 2009 using the Residential Assessment Instrument-Home Care. Results: Over the past 90 days, 55.7% of the 104 participants fell once, and 44.2% experienced recurrent falls (2+falls). In comparison of recurrent fallers with single fallers, there were significant differences in scores on the following factors: gender ($X^2$=4.22, p=.040), age ($X^2$=5.74, p=.017), educational level ($X^2$=5.22, p=.022), living arrangements ($X^2$=35.02, p<.001), cardiovascular diseases ($X^2$=17.10, p<.001), hypertension ($X^2$=4.43, p=.035), diabetes mellitus ($X^2$=4.44, p=.035), glaucoma ($X^2$=13.95, p<.001), Minimal Data Set (MDS)-Pain (t=-2.56, p=.012), fear of falling ($X^2$=4.08, p=.034), reduced vision (t=-3.06, p=.003), MDS-activity of daily living (t=3.46, p=.001), MDS-Instrumental Activities of daily living (t=3.24, p=.002), cognition (MDS-Cognition Performance Scale) (t=3.40, p=.001), and 'difficulties entering and leaving the house' ($X^2$=4.53, p=.033). Conclusion: It is important to assess the risk factors for recurrent falls and develop differentiated strategies that will help prevent recurrent falls. Additionally, utilizing a standardized tool, such as RAI-HC, would help health professionals assess multi-variate fall risk factors to facilitate comparisons of different community care settings.

• Journal of Korean Neurosurgical Society
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• 제30권9호
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• pp.1108-1114
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• 2001

Objective : Prognostic factors of metastatic brain tumors have been widely reported and their operative indications also have been extended gradually even to the poor grade patients. Authors intended to analyze the causative factors for the clinical outcome of metastatic brain tumors, especially with relevant to the poor prognosis by one year follow-up evaluation. Patients and Methods : The authors retrospectively studied the clinical characteristics of 46 cases(35 patients) with metastatic brain tumors among 466 cases(437 patients) which were operated on due to the brain tumor, during the period between January 1994 to June 1999. Statistical analysis was performed by using SPSS 8.0$^{(R)}$. A p-value of less than 0.05 was considered clinically significant. Result : Among the variable clinical factors in patients with metastatic brain tumors, Karnofsky Performance Scale (KPS) score of less than 70(16 patients), uncontrolled primary tumor(8 patients), and surgical resection without further adjuvant therapy(9 patients) showed statistically significant poor prognosis ; p value of 0.002, 0.032, and 0.001, respectively. Other tested variables, such as old age(greater than 65 years ; 10 patients), gender(male ; 20 patients), type of primary cancer(primary undefined ; 6 patients, lung cancer ; 15 patients), location(infratentorial ; 9 patients, sellar ; 5 patients), number of lesion(multiple ; 12 patients), and number of operation(multiple craniotomy ; 7 patients) were not related to the poor prognosis. Conclusions : The most common primary site of distant metastasis was lung. The poorer prognosis was highly correlated with various factors including low KPS score(<70), no postoperative adjuvant therapy, and uncontrolled primary tumors.

• 한국정보통신학회논문지
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• 제22권9호
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• pp.1185-1190
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• 2018

본 연구는 전세계적으로 증가하고 있는 조직 내 다양성에 대응할 수 있는 정보통신기술기반 다양성 관리 기능의 필요성을 제시하고 이를 가능하게 하는 전자인적자원관리의 역할에 대해 규명하고 있다. 성별, 인종, 연령과 같은 인구통계적 속성 뿐 아니라 교육적 배경, 기능적 배경, 근속년수 등 다양한 속성을 가진 인력을 채용하고 효율적으로 관리하는 것은 조직성과와 직결되는 문제라는 점에서 전략적으로도 매우 중요하다. 다양성 관리에 있어 정보통신기술을 제대로 활용하는 조직만이 비교우위를 얻을 수 있다는 점에서 정보통신기술을 활용한 다양성 관리가 조직과 관리자에게 주는 함의점에 대해 논의하였다.

• 대한임상검사과학회지
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• 제39권1호
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• pp.7-18
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• 2007

A total of 1,780 isolates of Enterococcus spp. were isolated from 63,133 clinical specimens from Dec 1, 2005 to Nov 1, 2006 in "C" hospital. Isolation frequencies of Enterococcus spp. were 50.9% for E. faecalis, 41.7% for E. faecium, and 7.4% for other Enterococcus spp. containing E. avium, E. gallinarum, E. casseliflavus, E. durans, E. hirae, and E. raffinosus. There were no significant difference between gender, but according to the age group analysis, Enterococcus spp. were more frequently isolated in patients over 50 years old (20.0~24.6%) than those isolated from the patients under the age of 0~49 (1.3~9.4%). In monthly analysis, Enterococcus spp. were the most frequently isolated in April (11.9%), but presented at lowest frequency in February (5.2%). Seasonal analysis did not show a significant difference. Over half of enterococci were isolated from random urine (44.9%) and catherterized urine (15.7%). Frequencies of vancomycin resistant E. faecalis and E. faecium were 0.1% and 31.0%, respectively. Teicoplanin resistant Enterococcus was 13.3% in E. faecalis, 17.6 % in E. faecium. The Enterococcus species showing over 80% susceptibility against antimicrobial agents were E. faecalis, E. durans and E. hirae in vancomycin; E. faecalis, E. gallinarum, E. casseliflavus, E. durans and E. hirae in ampicillin. The antimicrobial agent showing susceptibility against whole group of Enterococcus species was only linezolid (95.9%), and a selection of antimicrobial agent is necessary to do essential performance identification and susceptibility tests.

• 한국문헌정보학회지
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• 제45권4호
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• pp.271-286
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• 2011

The role of information in knowledge society has changed. Library refers to information centre, which is actively involved information collection and promoting use of for the development of individual and society. Modern libraries are the centres of interaction for all interested in accessing information and in participating in the marathon of the present competitive age. Information and a conducive environment of its free flow is a vital tool in all forms of human endeavour. It is the link pin of national development. For a nation to develop it needs to have and provide relevant, updated and adequate information on food security, health, democracy, population, education, family planning, youth empowerment, gender quality, environment etc. The information intermediaries are the persons to modulate these complexities and find match between the information sources and users needs to satisfaction of Ranganathan's law: Books are for use; Every reader his/her book; Every book its reader; Save the time of the reader; Library is a growing organism. The relative importance of these norms in modern context has been evident from experience, study, observations, discussions, etc., and only by scientists and technologists, but also by managers, planners, and policy makers. They recognize the usefulness of information in the performance of their needs information needs. Libraries are therefore proper management, provision and dissemination of such information. It is clearly visible in the contemporary context, that the libraries in the knowledge society are much more than the book depositories This article looks at the theory/practice divide in library and information science and particularly Ranganathan's contributions, basic statements remain as valid in substance if not in expression as -to-day as when they were promulgated, concisely representing the ideal service and organizational philosophy of libraries today.

• 대한영양사협회학술지
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• 제15권3호
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• pp.220-231
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• 2009

The principal objective of this study was to evaluate elementary students' awareness of the importance of hand washing, as well as their hand-washing behavior. The data was collected by self-reported questionnaire from 697 students in elementary schools with serving food in a classroom in Busan. Their hand-washing frequency was high, at '3~4 times per day (37.0%)'. 51.0% of the respondents did not wash their hands that often because they were 'not accustomed' to washing their hands, and 35.9% of respondents regarded washing their hands as 'annoying'. The most frequently reported hand washing agent was 'soap and water (71.4%)'. Approximately 95~98% of the respondents always washed their hands after using the bathroom, 87.9% of them washed their hands before eating food, and 86.7% of them washed their hands upon returning home. However, 27.3%, 34.1% and 65.9% of the respondents did not wash their hands after handling money, after eating, and after coughing or sneezing, respectively. Significant factors related to increased hand-washing frequency were gender (p<0.001) and the period of attendance at kindergarten (p<0.05). The mean scores of importance and performance of hand washing were significantly higher for girls than for boys. The group with higher rate (over 4.5/5.0) for the importance of sanitary hand-washing behavior showed significantly higher scores in hand-washing behavior before serving food and before eating than those of the lower rated group (below 4.0/5.0). This study shows that sanitation education is required not only for food handlers but also for students in school foodservices.

• 디지털융복합연구
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• 제16권10호
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• pp.389-398
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• 2018

본 연구는 호흡기 감염 전파 예방을 위한 기침예절에 대한 지식과 실행수준 및 영향요인을 파악하기 위해 시행하였다. 2018년 8월 13일부터 9월 19일까지 19세 이상 성인 250명을 대상으로 자가보고식 설문지를 이용하여 자료를 수집하였으며, 이 중 213명의 자료를 분석에 이용하였다. 연구결과 기침예절 지식과 실행수준은 100점으로 환산 시 평균 지식수준이 $70.99{\pm}19.92$점, 실행수준은 $70.63{\pm}10.25$점으로 중간 수준이었다. 기침예절 지식과 실행수준 간에는 유의한 양의 상관관계가 있었으며, 다중회귀분석에서 기침예절 실행에 영향을 미치는 요인으로는 성별, 평소 손수건을 가지고 다님, 평소 휴지를 가지고 다님, 일평균 손씻기 횟수, 기침예절에 대해 알고 있음, 기침예절 지식 수준이 유의하였다. 본 연구결과에서 확인된 기침예절 실행 영향 요인을 반영한 교육 프로그램의 개발과 적용이 필요하며, 기침예절 실행수준이 높아짐에 따라 호흡기 감염 전파 예방에 도움이 될 것이다.