• Korean Journal of Acupuncture
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• v.17 no.1
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• pp.1-10
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• 2000

Gamdutang aqua-acupuncture solution(GAS) and Gamdutang water-extracted solution(GWS) were prepared and tested for potential antitumor activites. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of $5{\times}\;and\;10{\times}$ of GAS resulted in more than 70% inhibition of growth in Ehrlich ascites tumor cells(EATC), hepa1c1c7 and A549. GAS at the concentration of $10{\times}\;and\;5{\times}$ revealed that more than 60% inhibition in HeLa. GWS showed more than 50% in hibition of growth with EATC, HeLa at the concentration of $5{\times}\;and\;10{\times}$. Toxicity assay with GWS in hepa1c1c7 and A549 revealed that more than 80% inhibition in growth at the concentration of $5{\times}\;and\;10{\times}$. In morphological study, the number of cells were decreased, and the shape of cells was round-form. Most of cells in detached in EATC, Hepa1c1c7, HeLa, and A549 with GAS. These results suggest that GAS has antitumor activity in vitro.

• Journal of Microbiology and Biotechnology
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• v.11 no.5
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• pp.772-775
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• 2001

A highly $CO_2$ tolerant microalga, Chlorella KR-1, has been isolated and used to fix $CO_2$ from actual flue gas. Growth of Chlorella KR-1 with the supply of flue gas from a liquified natural gas boiler was comparable to that obtained with 10% $CO_2$. Chlorella KR-1 produced from $CO_2$ fixation using the flue has about 50% crude protein with balanced amino acid profiles. Toxicity was not detected when the microalga was used as a feedstuff for chicks. These results indicate that the KR-1 cells could be a favorable protein source for poultry.

• Transactions on Electrical and Electronic Materials
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• v.3 no.3
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• pp.34-38
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• 2002

In this paper, efficiency estimation of toxicity fee fire resistance cable experiments was measured smoke density of toxicity free fire resistance polyolefin insulation material and electric field dependence of tree shape in low density polyethylene (LDPE). One of the most serious causes of failure in high-voltage cables, can be an electrical discharge across an internal gab or void in the insulating material. Treeing due to partial discharge is one of the main causes of breakdown in the insulating materials and reduction of the insulation life. Therefore the necessity for establishing a method to diagnose the aging of insulation materials and to predict the breakdown of insulation and research of the fire resistance character has become important. First, we have studied on electric field dependence of tree shape in LDPE about treeing phenomena occurring on the high electrical field. Second, the measurement method is the attenuation quantity of irradiation by smoke accumulating with in a closed chamber due to non-flaming heat decomposition and flaming combustion. A main cause of fire-growth and generating toxic gas when, it bums, should be dealt with great care in life. safety design. The fire gases were occurred carbon monoxide and decomposition than in polyolefin due to incomplete combustion of PVC, which has high content of carbon in chemical compound.

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.4
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• pp.408-421
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• 2016

Day and night sampling for gas and particle phases PAHs were carried out in Seoul to characterize gas and particle phases PAHs concentrations in day and night times. There was no significant difference between day and night time for particle phase PAHs concentrations and phase distribution of PAHs, while, gas phase PAHs concentrations in daytime were about 1/2 of nighttime concentrations in both summer and winter due to photochemical reaction of gas phase PAHs during daytime. A high fraction of cancer risk for PAHs was attributed to particle phase PAHs and the excess cancer risk in winter was higher than in summer. The excess cancer risk level of total(gas+particle) PAHs in summer was partially observed when both gas and particle phase PAHs concentrations were considered as risk assessment. Based on the diagnostic ratios and factor analysis of PAHs concentrations, combustion(coal and natural gas) and vehicular emission might be the most significant contributors of PAHs and major factors for determining of PAHs concentration were different between day and night times.

• Journal of Korean Society of Archives and Records Management
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• v.1 no.1
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• pp.231-243
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• 2001

The sterilization method of records by fumigation using mixed gas of methyl bromide(MB) and ethylene oxide(ETO) has been generally used as a way to protect biological deterioration by microorganisms and insects. In this study, we confirmed sterilization effect of MB and ETO [86 : 14(Vol.%)] on and analyzed toxicity on microorganisms isolated from records. To analyze sterilization effect of fumigation on microorganisms and insect, we have fumigated microorganisms and insect with a various amounts mixed gas of MB and ETO, and various exposure time. Insect was sterilized at all experimental conditions. In microorganisms, sterilization effect was detected only when the mixed gas was treated at $120g/m^3$ concentration for at least 24 hrs. To test the possibility of isolated microorganisms as a threat to human health, it was investigated that toxicity test using yeast, radish and cancer cells on microorganisms. Only Aspergillus oryzae had an inhibition effect on growth of yeast. radish and cancer cells, respectively. These results demonstrate that sterilization effect can occur at low concentrations of the mixed gas on insect but requires higher concentrations of the mixed gas on microorganisms. In addition to, it is suspected that the possibility of the microorganism as a threat to human health is little.

• Structural Engineering and Mechanics
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• v.84 no.6
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• pp.733-741
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• 2022

The amount of natural gas that is used on a worldwide scale is continuously going up. Natural gas and acidic components, such as hydrogen sulfide and carbon dioxide, cause significant corrosion damage to transmission lines and equipment in various quantities. One of the fundamental processes in natural gas processing is the separation of acid gases, among which the safety and environmental needs due to the high toxicity of hydrogen sulfide and also to prevent wear and corrosion of pipelines and gas transmission and distribution equipment, the necessity of sulfide separation Hydrogen is more essential than carbon dioxide and other compounds. Given this problem's significance, this endeavor aims to extend the lifespan of the transmission lines' pipes for gas and oil. Zinc oxide nanoparticles made from the environmentally friendly source of Allium scabriscapum have been employed to accomplish this crucial purpose. This is a simple, safe and cheap synthesis method compared to other methods, especially chemical methods. The formation of zinc oxide nanoparticles was shown by forming an absorption peak at a wavelength of about 355 nm using a spectrophotometric device and an X-ray diffraction pattern. The size and morphology of synthesized nanoparticles were determined by scanning and transmission electron microscope, and the range of size changes of nanoparticles was determined by dynamic light scattering device.

• Journal of The Korean Society of Clinical Toxicology
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• v.2 no.1
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• pp.49-53
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• 2004

A chlorine gas is a common irritant and when exposed, it result in mild occular, oropharyngeal, or respiratory symptoms. In severe case, however, it may result in pulmonary edema, interstitial pneumonia, or respiratory failure. We report the case of 29-year-old and 46-year-old men is accidentally exposed to chlorine gas during cleaning water. The patients complained dyspnea, chest tightness, cough and both eye pain. During hospitalization, they were treated with inhalation of humidified oxygen, beta-adrenergic agonist and $2\%$ sodium bicarbonate. After several days, patients were discharged without respiratory symptoms and complication. In treatment of chlorine gas toxicity the inhalation of sodium bicarbonate is a possible initial therapy can improve respiratory symptoms in spite of lack of evidence.

• Journal of the Korean Institute of Gas
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• v.17 no.6
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• pp.58-66
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• 2013

Among the risks which can be faced with fire, combustion toxicity is a significant influence on the survival. Fire toxicity researches have been limited generally on the lethal aspects. In this study, HF gas which can be generated from fire, and also found in general industrial site was used for analysis. Blood analysis and biochemistry analysis performed to find internal demage of experimental animals which were used for measuring average activity stopping time from Animal test(KS F2271: Gas hazard test). In addition, Using the malondialdehyde analysis, indicators of oxidative damage, we had quantitative analysis to target lymphocyte for measuring the oxidative damage caused by toxic substances.

• Toxicological Research
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• v.17 no.1
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• pp.27-32
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• 2001

Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that consumption of EO treated foods might cause harmful effects in human. In Korea, the use EO gas for food treatment was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to evaluate the safety of irradiated ginseng on embryo and fetal developmental toxicity effects in rats. Either EO gas fumigated or $\gamma$-irradiated ginseng was administered to pregnant Wistar rats by oral gavage from gestational day 7 to 17. The amount of irradiation used in this study was 5, 10 and 30 kGy, respectively. There were no treatment related changes of dams in deaths, clinical signs, food consumption and body/organ weight. No treatment related changes in implantation ratio, litter size, sex ratio and body/organ weight of fetuses were observed. Also, no F1fetuses with external, visceral, head and skeletal mal-formation were observed. The results of this study showed that $\gamma$-irradiated ginseng, up to 30 kGy, has no adverse effects on fetal development of rats.

• Toxicological Research
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• v.17 no.1
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• pp.17-25
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• 2001

Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that consumption of EO treated foods might cause harmful effects in human. In Korea, the use EO gas for sterilization of food was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to evaluate the safety of irradiated ginseng on peri- and postnatal developmental toxicity in rats. Either EO gas fumigated or gamma-irradiated ginseng was administered to pregnant Wistar rats by oral gavage from gestational day 16 to postnatal day 21. The amount of irradiation used in this study was 5, 10 and 30 kGy, respectively. There were no treatment related changes of dams in deaths, clinical signs, and parturition. No treatment related changes in food consumption, body/organ weight and lactation of dams were observed. Also, no F1 fetuses in external abnormality, physical development, reflex/sensory junctions and behavioral development were found. The results of this study showed that gamma-irradiated ginseng, up to 30 kGy, has no adverse effects on the peri- and postnatal development of rats.