• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5325-5325
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• 2012

• Acta Via Serica
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• 제6권2호
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• pp.61-90
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• 2021

Recent excavations in Qinghai Province, China, have disclosed textiles and artworks from Tuyuhun-Tubo (Tibetan) tombs, dated to the 7^th-9^th centuries, that suggest artistic and cultural exchanges along an external southern branch of the main Silk Road, between Gansu and Sichuan Provinces, across the Qinghai-Tibetan plateau toward the Himalayas. Many similar textiles, possibly from this area, have appeared lately on the art market and ended in private collections. Although these textiles, dated to the early Tibetan period, follow a popular prototype established in Central Asia in the 6^th century, the technical features, colors, and other indigenous elements suggest that they were woven in workshops different from those established between Sogdiana and Gansu. The exhibition "Cultural Exchange Along the Silk Road - Masterpieces of the Tubo Period," organized by the Dunhuang Research Academy and the Pritzker Collaborative Art between July and October 2019 in Dunhuang, Gansu, was a groundbreaking event that gathered scholarly attention on early Tibetan material culture, but a relevant publication is still forthcoming. In my previous work, I briefly discussed a group of silk textiles, possibly from Qinghai or Sichuan, that I analyzed in 2014 in the China National Silk Museum in Hangzhou, Zhejiang. In light of the recent material excavated, published online, or displayed in Dunhuang, in this article, I reevaluate the data previously collected, and discuss in detail the technical and iconographic features of one of the fragments held in Hangzhou. Eventually, the piece was recognized as the ending part of a large panel, which is now in the Abegg Stiftung in Riggisberg, Switzerland.

• Structural Engineering and Mechanics
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• 제84권4호
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• pp.503-515
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• 2022

Based on the sliding isolation concrete LSS (liquid-storage structure), the specific seismic vulnerability is analyzed according to the general failure mode. In this study, 12 seismic inputs with different characteristics are used, and their acceleration peak values are modulated. By inputting these waves to the sliding isolation concrete storage structure, the finite-element models of different concrete rectangular LSSs are obtained and analyzed, and the failure probabilities are obtained according to the IDA (incremental dynamic analysis) curves of the structure. The results show that when the seismic acceleration peak value gradually increases from 0.1 g to 1.0 g, the failure probability of LSS gradually increases with the increase in friction coefficient. However, the failure probability of a sliding isolation LSS is less than 100% and far less than the failure probability of a non-isolated rectangular LSS, which shows that an isolated liquid storage structure continues working under a big earthquake. Thus, the sliding isolation for the concrete LSS has a significant damping effect.

• 한국농공학회:학술대회논문집
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• 한국농공학회 1999년도 Proceedings of the 1999 Annual Conference The Korean Society of Agricutural Engineers
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• pp.30-40
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• 1999

부족 (또는 적자) 조절관개는 용수절약 및 작물수량 증수를 위한 주요 방법중의 하나이다. 부족조절관개는 작물과 물의 관계에 근거를 두고 있다. 부족조절관개의 이론은 Shaanxi 및 Gansu 성에서의 실험자료을 이용하여 분석되었다. 부족조절관래에서의 실용상의 문제점은 ; 작물-물관계의 불확실성, 부족조절관개에서의 적정 생육기와 물부족의 정도, 관개조직과 기술에 대한 부족조절관개의 필요조건등이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1781-1787
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• 2015

Background: miRNAs are relatively recently discovered cancer biomarkers which have important implications for cancer early diagnosis, treatment and estimation of prognosis. Here we focussed on expression of mir-196a-5p in gastric cancer tissues and cell lines so as to analyse its significance for clinicopathologic characteristics and generate enriched KEGG pathways clustered by target genes for exploring its potential roles as a biomarker in gastric cancer. Materials and Methods: The expression of mir-196a-5p in poorly, moderate and well differentiated gastric cancer cell lines compared with GES-1 was detected by RT-qPCR, and the expression of mir-196a-5p in gastric cancer tissues comparing with adjacent non cancer tissues of 58 cases were also assessed by RT-qPCR. Subsequently, an analysis of clinical significance of mir-196a-5p in gastric cancer and enriched KEGG pathways was executed based on the miRWalk prediction database combined with bioinformatics tools DAVID 6.7 and Mirfocus 3.0. Results: RT-qPCR showed that mir-196a-5p was up-regulated in 6 poorly and moderate differentiated gastric cancer cell lines SGC-7901, MKN-45, MKN-28, MGC-803, BGC-823, HGC-27 compared with GES-1, but down-regulated in the highly differentiated gastric cancer cell line AGS. Clinical data indicated mir-196a-5p to beup-regulated in gastric cancer tissues (47/58). Overexpression of mir-196a-5p was associated with more extensive degree of lymph node metastasis and clinical stage (P < 0.05; x2 test). Enriched KEGG pathway analyses of predicted and validated targets in miRWalk combined with DAVID 6.7 and Mirfocus 3.0 showed that the targeted genes regulated by mir-196a-5p were involved in malignancy associated biology. Conclusions: Overexpression of mir-196a-5p is associated with lymph node metastasis and clinical stage, and enriched KEGG pathway analyses showed that targeted genes regulated by mir-196a-5p may contribute to tumorgenesis, suggesting roles as an oncogenic miRNA biomarker in gastric cancer.

• 한국농공학회지
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• 제42권
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• pp.31-37
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• 2000

Regulated Deficit Irrigation (RDI) is one of the most important measures for the water-saving and high yield of crops. RDI is based on the crop and water relations. The theories of RDI were analyzed using the experiment data in Shaanxi and Gansu Province. There are several problems of RDI in practical use, which include; the uncertainty of crop-water relations, the proper growth stages and water deficit degree of RDI applied, and the requirements of RDI to irrigation system and irrigation techniques.

• Parasites, Hosts and Diseases
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• 제53권3호
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• pp.345-348
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• 2015

Toxoplasma gondii is a eukaryotic parasite of the phylum Apicomplexa, which infects all warm-blood animals, including humans. In the present study, we examined sequence variation in dense granule 20 (GRA20) genes among T. gondii isolates collected from different hosts and geographical regions worldwide. The complete GRA20 genes were amplified from 16 T. gondii isolates using PCR, sequence were analyzed, and phylogenetic reconstruction was analyzed by maximum parsimony (MP) and maximum likelihood (ML) methods. The results showed that the complete GRA20 gene sequence was 1,586 bp in length among all the isolates used in this study, and the sequence variations in nucleotides were 0-7.9% among all strains. However, removing the type III strains (CTG, VEG), the sequence variations became very low, only 0-0.7%. These results indicated that the GRA20 sequence in type III was more divergence. Phylogenetic analysis of GRA20 sequences using MP and ML methods can differentiate 2 major clonal lineage types (type I and type III) into their respective clusters, indicating the GRA20 gene may represent a novel genetic marker for intraspecific phylogenetic analyses of T. gondii.

• Parasites, Hosts and Diseases
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• 제56권3호
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• pp.237-245
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• 2018

Toxoplasma gondii can infect all the vertebrates including human, and leads to serious toxoplasmosis and considerable veterinary problems. T. gondii heat shock protein 60 (HSP60) is associated with the activation of antigen presenting cells by inducing initial immune responses and releasing inflammatory cytokines. It might be a potential DNA vaccine candidate for this parasite. A pVAX-HSP60 DNA vaccine was constructed and immune responses was evaluated in Kunming mice in this study. Our data indicated that the innate and adaptive immune responses was elicited by successive immunizations with pVAX-HSP60 DNA, showing apparent increases of CD3e+CD4+ and CD3e+CD8a+ T cells in spleen tissues of the HSP60 DNA-immunized mice ($24.70{\pm}1.23%$ and $10.90{\pm}0.89%$, P<0.05) and higher levels of specific antibodies in sera. Furthermore, the survival period of the immunized mice ($10.53{\pm}4.78day$) were significantly prolonged during the acute T. gondii infection. Decrease of brain cysts was significant in the experimental group during the chronic infection (P<0.01). Taken together, TgHSP60 DNA can be as a vaccine candidate to prevent the acute and chronic T. gondii infections.

• Geomechanics and Engineering
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• 제13권6호
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• pp.929-946
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• 2017

Composite foundation treated with compaction piles can eliminate collapsibility and improve the bearing capacity of foundation in loess area. However, the large number of piles in the composite foundation leads to difficulties in the analysis of such type of engineering works. This paper proposes two simplified methods to quantify the stability of composite foundation treated with a large number of compaction piles. The first method is based on the principle of making the area replacement ratios of the simplified model as the same time as the practical engineering situation. Then, discrete piles arranged in a triangular shape can be simplified in the model where the annular piles and compacted soil are arranged alternately. The second method implements equivalent continuous treatment in the pile-soil area and makes the whole treated region equivalent to a type of composite material. Both methods have been verified using treated foundation of an oil storage tank. The results have shown that the differences in the settlement values obtained from the water filled test in the field and those calculated by the two simplified methods are negligible. Using stability analysis, the difference ratios of the static and dynamic safety factors of the composite foundation treated with compaction piles calculated by these two simplified methods are found to be 3.56% and 5.32%, respectively. At the same time, both static and dynamic safety factors are larger than the general safety factor, which should be greater than or equal to 2.0 according to the provisions in civil engineering. This indicates that after being treated with compaction piles, the bearing capacity of the composite foundation is effectively improved and the foundation has enough safety reserve.

• Structural Engineering and Mechanics
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• 제81권6호
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• pp.691-703
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• 2022

To obtain the seismic response of lead-cored rubber, shape memory alloy (SMA)-rubber isolation Plate-shell Integrated Concrete Liquid-Storage Structure (PSICLSS), based on a PSICLSS in a water treatment plant, built a scale experimental model, and a shaking table test was conducted. Discussed the seismic responses of rubber isolation, SMA-rubber isolation PSICLSS. Combined with numerical model analysis, the vibration characteristics of rubber isolation PSICLSS are studied. The results showed that the acceleration, liquid sloshing height, hydrodynamic pressure of rubber and SMA-rubber isolation PSICLSS are amplified when the frequency of seismic excitation is close to the main frequency of the isolation PSICLSS. The earthquake causes a significant leakage of liquid, at the same time, the external liquid sloshing height is significantly higher than internal liquid sloshing height. Numerical analysis showed that the low-frequency acceleration excitation causes a more significant dynamic response of PSICLSS. The sinusoidal excitation with first-order sloshing frequency of internal liquid causes a more significant sloshing height of the internal liquid, but has little effect on the structural principal stresses. The sinusoidal excitation with first-order sloshing frequency of external liquid causes the most enormous structural principal stress, and a more significant external liquid sloshing height. In particular, the principal stress of PSICLSSS with long isolation period will be significantly enlarged. Therefore, the stiffness of the isolation layer should be properly adjusted in the design of rubber and SMA-rubber isolation PSICLSS.