• Title/Summary/Keyword: Gamma analysis

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Decomposition of Antibiotics (Cefaclor) by Ionizing Radiation: Optimization and Modeling Using a Design of Experiment (DOE) Based on Statistical Analysis

  • Yu, Seung-Ho;Chang, Soon-Woong;Lee, Si-Jin;Cho, Il-Hyoung
    • Environmental Engineering Research
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    • v.14 no.2
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    • pp.81-87
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    • 2009
  • The decomposition of antibiotics (cefaclor) by gamma irradiation in aqueous solutions was experimentally evaluated. To obtain a mutual interaction between two factors (antibiotics concentrations and radiation doses) and to optimize these factors during the process, experimental design and statistical analysis were employed. The decomposition capability of the gamma radiation was also mathematically described as a function of cefaclor concentration and gamma-ray dose using the statistical analysis. The results showed that the cefaclor concentration ($X_1$) in the response $Y_1$ (Reduction of cefaclor concentration) and gamma-ray dose ($X_2$) in the response $Y_2$ (Removal efficiency (%) of cefaclor concentration) exhibited a significantly positive effect, whereas gamma-ray dose ($X_2$) in the response $Y_1$ showed a significantly negative effect. The estimated ridge of maximum responses and optimal conditions for $Y_1$:($X_1$,$X_2$)=(25 mg/L, 350 Gy) and $Y_2$:($X_1$,$X_2$)=(21 mg/L, 565 Gy) using canonical analysis were 4.37 mg/L of reduction of cefaclor concentration and 98.35% of removal efficiency of cefaclor concentration, respectively. The measurement values agreed well with the predicted ones, thereby confirming the suitability of the model for $Y_1$ and $Y_2$ and the success of the experimental design in optimizing the conditions of the gamma irradiation process.

Development of an efficient method of radiation characteristic analysis using a portable simultaneous measurement system for neutron and gamma-ray

  • Jin, Dong-Sik;Hong, Yong-Ho;Kim, Hui-Gyeong;Kwak, Sang-Soo;Lee, Jae-Geun;Jung, Young-Suk
    • Analytical Science and Technology
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    • v.35 no.2
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    • pp.69-81
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    • 2022
  • The method of measuring and classifying the energy category of neutrons directly using raw data acquired through a CZT detector is not satisfactory, in terms of accuracy and efficiency, because of its poor energy resolution and low measurement efficiency. Moreover, this method of measuring and analyzing the characteristics of low-energy or low-activity gamma-ray sources might be not accurate and efficient in the case of neutrons because of various factors, such as the noise of the CZT detector itself and the influence of environmental radiation. We have therefore developed an efficient method of analyzing radiation characteristics using a neutron and gamma-ray analysis algorithm for the rapid and clear identification of the type, energy, and radioactivity of gamma-ray sources as well as the detection and classification of the energy category (fast or thermal neutrons) of neutron sources, employing raw data acquired through a CZT detector. The neutron analysis algorithm is based on the fact that in the energy-spectrum channel of 558.6 keV emitted in the nuclear reaction 113Cd + 1n → 114Cd + in the CZT detector, there is a notable difference in detection information between a CZT detector without a PE modulator and a CZT detector with a PE modulator, but there is no significant difference between the two detectors in other energy-spectrum channels. In addition, the gamma-ray analysis algorithm uses the difference in the detection information of the CZT detector between the unique characteristic energy-spectrum channel of a gamma-ray source and other channels. This efficient method of analyzing radiation characteristics is expected to be useful for the rapid radiation detection and accurate information collection on radiation sources, which are required to minimize radiation damage and manage accidents in national disaster situations, such as large-scale radioactivity leak accidents at nuclear power plants or nuclear material handling facilities.

Effects of IFN-γ on IL-18 Expression in Pregnant Rats and Pregnancy Outcomes

  • Si, Li-Fang;Zhang, Shou-Yan;Gao, Chun-Sheng;Chen, Shu-Lin;Zhao, Jin;Cheng, Xiang-Chao
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.10
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    • pp.1399-1405
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    • 2013
  • The present study focused on establishing the effects of interferon-gamma (IFN-${\gamma}$) on interleukin-18 (IL-18) expression patterns and pregnancy outcomes in pregnant rats. Pregnant rats at the post-implantation stage were randomized into control, low IFN-${\gamma}$ (L-IFN-${\gamma}$) and high IFN-${\gamma}$ groups (H-IFN-${\gamma}$) that received normal saline, 100 IU/g of IFN-${\gamma}$ and 500 IU/g of IFN-${\gamma}$ vaginal muscular injection, respectively. The effects of IFN-${\gamma}$ on IL-18 expression and pregnancy outcomes were assessed systematically using several methods, including immunohistochemistry streptavidin-perosidase (SP), image pattern analysis, enzyme-linked immune-sorbent assay (ELISA), whole blood count (WBC) count, microscopy and visual observation. IL-18 was detected in the uteri of all pregnant rats, and mainly distributed in the endometrium, decidual cells, vascular endothelium and myometrium. Immunohistochemistry and image pattern analyses revealed significantly lower IL-18 expression in the H-IFN-${\gamma}$ group compared to the L-IFN-${\gamma}$ and control groups (p<0.01), indicating that high doses of IFN-${\gamma}$ induce downregulation of IL-18 in the uterus of pregnant rats. ELISA results disclosed that IL-18 expression in peripheral blood of the H-IFN-${\gamma}$ group was lower than that of the L-IFN-${\gamma}$ group (p<0.05), and significantly reduced compared to the control group (p<0.01). Moreover, the number of peripheral leukocytes in the H-IFN-${\gamma}$ group was significantly higher than those in the control and L-IFN-${\gamma}$ groups (p<0.01). Morphology analysis showed no evident differences between the L-IFN-${\gamma}$ and control groups. However, for the H-IFN-${\gamma}$ group, uterine mucosa bleeding, necrosis and excoriation were observed using microscopy. Visual observation revealed marroon, swelling, crassitude and no embryo in the uterus, which are obvious indicators of abortion. These results indicate that IFN-${\gamma}$ plays a regulatory role in IL-18 expression in the uterus and peripheral blood of pregnant rats at the post-implantation stage. Moreover, high levels (500 IU/g) of IFN-${\gamma}$ influence normal pregnancy at the early stages in rats by downregulating IL-18 expression in the uterus and peripheral blood and increasing the number of peripheral leukocytes, consequently triggering termination of pregnancy.

Derivation of Optimal Design Flood by Gamma and Generalized Gamma Distribution Models(I) - On the Gamma Distribution Models - (Gamma 및 Generalized Gamma 분포 모형에 의한 적정 설계홍수량의 유도 (I) -Gamma 분포 모형을 중심으로-)

  • 이순혁;박명근;정연수;맹승진;류경식
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.39 no.3
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    • pp.83-95
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    • 1997
  • This study was conducted to derive optimal design floods by Gamma distribution models of the annual maximum series at eight watersheds along Geum , Yeong San and Seom Jin river Systems, Design floods obtained by different methods for evaluation of parameters and for plotting positions in the Gamma distribution models were compared by the relative mean errors and graphical fit along with 95% confidence interval plotted on Gamma probability paper. The results were analyzed and summarized as follows. 1.Adequacy for the analysis of flood flow data used in this study was confirmed by the tests of Independence, Homogeneity and detection of Outliers. 2.Basic statistics and parameters were calculated by Gamma distribution models using Methods of Moments and Maximum Likelihood. 3.It was found that design floods derived by the method of maximum likelihood and Hazen plotting position formular of two parameter Gamma distribution are much closer to those of the observed data in comparison with those obtained by other methods for parameters and for plotting positions from the viewpoint of relative mean errors. 4.Reliability of derived design floods by both maximum likelihood and method of moments with two parameter Gamma distribution was acknowledged within 95% confidence interval.

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FINITE ELEMENT ANALYSIS FOR A MIXED LAGRANGIAN FORMULATION OF INCOMPRESSIBLE NAVIER-STOKES EQUATIONS

  • Kim, Hong-Chul
    • Journal of the Korean Mathematical Society
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    • v.34 no.1
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    • pp.87-118
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    • 1997
  • This paper is concerned with a mixed Lagrangian formulation of the wiscous, stationary, incompressible Navier-Stokes equations $$ (1.1) -\nu\Delta u + (u \cdot \nabla)u + \nabla_p = f in \Omega $$ and $$ (1.2) \nubla \cdot u = 0 in \Omega $$ along with inhomogeneous Dirichlet boundary conditions on a portion of the boundary $$ (1.3) u = ^{0 on \Gamma_0 _{g on \Gamma_g, $$ where $\Omega$ is a bounded open domain in $R^d, d = 2 or 3$, or with a boundary $\Gamma = \partial\Omega$, which is composed of two disjoint parts $\Gamma_0$ and $\Gamma_g$.

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A Cross-Sectional Study on ${\gamma}-GTP$ and its Related Factors in Male Workers (일부 남성근로자에서 ${\gamma}-GTP$와 관련된 요인에 대한 단면연구)

  • Kim, Keon-Yeop;Lee, Jong-Hyun;Ha, Young-Ae;Lee, Kyung-Eun;Kam, Sin
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.2
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    • pp.169-174
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    • 2002
  • Objective : To investigate gamma-Glutamyltransferase (${\gamma}-GTP$) and its related factors in male industrial workers. Method : Five hundred and tony male workers without heart disease, diabetes mellitus, renal disease, hepatitis, and other liver diseases were surveyed in October 1998. Blood samples were collected to test for ${\gamma}-GTP$, total-cholesterol and fasting blood glucose. A self-administered questionnaire survey on life style was also done. Results : The total geometric mean value of ${\gamma}-GTP$ was 30.6 U/L. According to a univariate analysis: age, BMI(body mass index, $kg/m^2$), alcohol consumption, current smoking, stress, diastolic blood pressure, and blood total cholesterol were significantly associated with ${\gamma}-GTP$(p<0.05). From a multiple regression analysis: BMI, alcohol consumption, current smoking, diastolic blood pressure and total-cholesterol were significantly related to ${\gamma}-GTP$(p<0.05). Coffee consumption was negatively related to ${\gamma}-GTP$, but not significantly. Conclusion : We recommend that a change in health behavior (i.e. reducing alcohol intake, controlling BMI and not smoking) is necessary to decrease ${\gamma}-GTP$ in male workers.

Analysis of Surplus and Dficit-using Runs for Monthly Streamflow (월유출량에 대한 Run-Length의 해석)

  • Gang, Gwan-Won;An, Gyeong-Su;Kim, Yang-Su
    • Water for future
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    • v.18 no.4
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    • pp.317-325
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    • 1985
  • In the analysis, monthly streamflow records atthe gauging station in Nakdong, Han and Geum river were used. Also, the fitness of monthly streamflow to Gamma and Long-normal distribution was tested by Kolomogorv-Smirnov test. The results obtained in this study can be summarized as follws (1) The fitness of monthly streamflow to two-parameter Gamma distribution was tested by Kolomorov-Smirnov test, which fits well to this Gamma distribution (2) The Run-length and Run-sum were simulated by the Gamma model. In this result, run-length and Run-sum of monthly streamflow were fit for Gamma model (3) The mean decreases (increases) the expected surplus (deficit) Run-Sum of the monthly streamflow. The higher the truncation level of negative Run-length and Run-sum the larger is the effect of mean.

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Elemental Analysis by Neutron Induced Nuclear Reaction - Prompt Gamma Neutron Activation Analysis for Chemical Measurement - (중성자 핵반응을 이용한 원소 검출기술 - 즉발감마선 중성자 방사화분석법을 이용한 검출기술 -)

  • Song, Byung Chul;Park, Yong Joon;Jee, Kwang Yong
    • Analytical Science and Technology
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    • v.16 no.5
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    • pp.1041-1051
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    • 2003
  • Neutron induced prompt gamma activation analysis (PGAA) offers a nondestructive, sensitive and relatively rapid method for the determination of trace and major elements and is proven to be convenient for online analysis of minerals, metals, coal, cement, petrochemical, coating, paper as well as many other materials and products. The technique has found many uses in medicine, industry, research, security and the detection of contraband items. This report reviews the present status and future trends of the PGAA techniques. Requirements for the system are neutron source, high resolution HPGe detectors with a high-voltage power supply, an amplifier, analog-to-digital converter, and a multichannel analyzer for the detection and measurement of prompt ${\gamma}$-ray emit form the neutron capture elements. Introducing a ${\gamma}$-${\gamma}$ coincidence system also improves the quality of the ${\gamma}$-ray spectrum by suppressing the background created from the Compton scattering of high energy prompt ${\gamma}$-rays. A PGAA system using a $^{252}Cf$ neutron source is currently under construction for the on-line measurement of several elements in aqueous samples at KAERI. The system can be applied for the detection of chemical weapons and explosives as well as various narcotics.

Quantitative Analysis of ${\gamma}-oryzanol$ in Rice Bran (미강의 약리성분 감마-오리자놀의 정량)

  • Kwak, Tae-Soon;Park, Hee-Juhn
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.2
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    • pp.113-118
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    • 1997
  • Phytochemical analysis on rice bran and its pitch was performed by the tool of TLC, UV- and IR-spetroscopy, so that it was found that they contained ${\gamma}-oryzanol$ and free sterol. GC-MS analysis of free sterol revealed that it was composed of ${\beta}-sitosterol$, campesterol and stigmasterol. Successive phytochemical analysis of ${\gamma}-oryzanol$ revealed that it was composed of ferulic acid ester of triterpene and sterol, respectively. Triterpene moieties of ${\gamma}-oryzanol$ were identified as follows: cycloartanol, cycloartenol, 24-methylenecycloartanol and unknown triterpene; And sterol moieties were found to be identical with free sterols. In addition, characteristic absorption band in UV spectrum (220-340 nm) was exclusively due to ${\gamma}-oryzanol$. Thus, it was suggested that rice brans of nearly all species of Oryza sativa can be quantitatively analyzed by UV absorption spectrometry, even when water soluble pigments was contained in the rice bran.

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Region-wise evaluation of gamma-ray exposure dose in decontamination operation after a nuclear accident

  • Jeong, Hae Sun;Hwang, Won Tae;Han, Moon Hee;Kim, Eun Han;Lee, Jo Eun;Lee, Cheol Woo
    • Nuclear Engineering and Technology
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    • v.53 no.8
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    • pp.2652-2660
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    • 2021
  • The gamma-ray exposure doses in decontamination operation after a nuclear accident were evaluated with a consideration of various geometrical conditions and specific gamma-ray energies. The calculation domain is organized with three residence types and each form is divided into two kinds of geometrical arrangements. The position-wise air KERMA values were calculated with an assumption of evenly distributed gamma-ray source based on Monte Carlo radiation transport analysis using the MCNP code. The radioactivity is initially set to be unity to be multiplied by the deposition value measured in the actual accident condition. The workforce data set depending on the target object was determined by modifying the Fukushima report. The external exposure doses for decontamination workers were derived from the calculated KERMA values and the workforce analysis. These results can be used to efficiently determine the workforce required by the characteristics of the area and the structure to be decontaminated within the dose limits.