• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5171-5174
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• 2014

Background: The increase in breast cancer awareness and widespread use of mammographic screening has led to an increased detection of (non-palpable) breast cancers that cannot be discovered through physical examination. One of the methods used in the diagnosis of these cancers is vacuum-assisted core biopsy, which prevents a considerable number of patients from undergoing surgical procedures. The aim of this study was to present the results of stereotactic vacuum-assisted core biopsy for suspicious breast lesions. Materials and Methods: Files were retrospectively scanned and data on demographic, radiological and pathological findings were recorded for patients who underwent stereotactic vacuum-assisted core biopsy due to suspicious mammographic findings at the Interventional Radiology Centre of the Florence Nightingale Hospital between January 2010, and April 2013. Statistical analysis was carried out using Pearson's Chi-square, continuity correction, and Fisher's exact tests. Results: The mean age of the patients was 47 years (range: 36-70). Biopsies were performed due to BIRADS 3 lesions in 8 patients, BIRADS 4 lesions in 77 patients, and BIRADS 5 lesions in 3 patients. Mammography elucidated clusters of microcalcifications in 73 patients (83%) and focal lesions (asymmetrical density, distortion) in 15 patients (17%). In terms of complications, 1 patient had a hematoma, and 2 patients had ecchymoses (3/88; 3.3%). The histopathologic results revealed benign lesions in 63 patients (71.6%) and malignant lesions in 25 patients (28.4%). The mean duration of the procedure was 37 minutes (range: 18-55). Although all of the BIRADS 3 lesions were benign, 22 (28.6%) of the BIRADS 4 lesions and all of the BIRADS 5 lesions were malignant. Among the malignant cases, 80% were in situ, and 20% were invasive carcinomas. These patients underwent surgery. Conclusions: In cases where non-palpable breast lesions are considered to be suspicious in mammography scans, the vacuum-assisted core biopsy method provides an accurate histopathologic diagnosis thus preventing a significant number of patients undergoing unnecessary surgical procedures.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.5D
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• pp.727-737
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• 2011

The emergency restoration scenarios for efficient railway accident management and restoration were developed. The emergency restoration procedures defined by the worst case of emergency restoration and the important events was proposed based on questionnaires from specialists and the result of survey. Via these studies, the railway accident in the tunnel could be the worst case among all railway accident types. Therefore, educations for a restoration team in confined area condition should be planned and performed to recover the worst case accident. In order for the emergency restoration, when a railway accident is occurred, the restoration should be performed in orders of handing collapse of facilities, burying track, and derailment of vehicle in tunnel based on the statistical analysis. The result of priorities were established by the period of restoration. The standard operation system for efficient railway accident management was developed by synthesizing the worst case for rapid emergency restoration, and important events for the standard operation procedures according to each emergency restoration type. Through this study, the restoration operation system of railway accident are recommended. This paper suggests to develop emergency restoration scenarios for the efficient railway accident management and recovery system. The study results will contribute not only for insuring punctuality, but also for minimizing delays from accidents. Therefore, emergency restoration scenarios will play a major role in the SOP for the damage limitation and the prevention of accident spread.

• Journal of Yeungnam Medical Science
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• v.24 no.2
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• pp.344-350
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• 2007

Laryngo-tracheal perforation caused by the use of a stylet during tracheal intubation is a rare complication. We present a case of subcutaneous emphysema and connective tissue inflammation after tracheal intubation. The patient was a 41-year-old male undergoing general anesthesia for an appendectomy. The intubation was difficult during laryngoscopy (Cormack- Lehane Grade III). An assistant provided an endotracheal tube with a stylet inside while the laryngoscope was in place. During intubation, a short, dull sound was heard with a sudden loss of resistance after the distal tip of the endotracheal tube passed the rima glottis. A sonogram and computerized tomography revealed subcutaneous emphysema from the neck to the upper mediastinum and fluid collection between the trachea and the thyroid. This lesion appeared to have been caused by the protruded, loose stylet. Anesthesiologists should be aware of the damage a loose stylet protruding beyond the tip of the endotracheal tube can cause.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.176-187
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• 2018

The Korean government has been encouraging 'continuous' post-pump priming project management through relevant local personnel planning, action, and management, upon the selection of 68 sites for urban regeneration as part of the New Deal Project. This study assessed the utilization characteristics of containers, the socio-experimental temporary occupation facilities, as a tool for 'sustainable' urban regeneration. This is to identify the potential limitations of urban regeneration by the utilization of containers as public sector temporary occupation facilities and to provide adequate directions based on its efficacy. By comparing three Korean cases with the Japanese WaiWai project, in terms of 10 elements, the preoccupations with the social trend and scenery, and undifferentiated functions of the facilities focusing on the commercial or working aspects have been identified as limitations of Korean cases. Based on the analyses, the following are suggested as plausible approaches to utilize socio-experimental containers for sustainable urban regeneration: 1. Planning and management should be done by the same organization because the absence of the planning party's participation in the management likely leads to the pursuit of only profits. 2. Diversification and combinations of different utilization purposes of a single site and numerous planning of experimental container uses are in need. 3. Accommodations of heavy commercial uses lead to a decline in the continuity of follow-up projects and a change in the urban regeneration directions. Therefore, it is important to include a public socio-experimental program rather than a simple commercial or promotion program for the following urban renewal project.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.10
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• pp.345-353
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• 2020

On conventional railway lines, trains with different speeds are operated. Therefore, trains moving on curved sections with cants must accept various ranges of balanced cants, cant deficiency, and cant excess, which is essential for the comfort and safety of train operation. In this study, the correlation between the curve radius, cant, and train speed on a track was analyzed to check the cant range that satisfies the criteria of train types, operation speed, cant deficiency, and cant excess. Also, the range of setting the cant by the curve radius and balanced cant were calculated by a regression analysis of train speed according to the frequency of operation in the case of mixed trains. The results could make it possible to improve the speed of the operation route, reduce the loss of ride quality, reduce the risk of derailing caused by cant deficiency, and minimize the load deflection by excess cant. This will ensure the safety of trains running on curves and improve the efficiency of track maintenance.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.8
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• pp.1179-1189
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• 2006

This experiment was designed to examine the effects of supplemental vitamin D on laying performance, metabolic profile and egg quality of hens fed diets containing different fat sources and levels. Lohman strains (n = 480) were assigned to one of 10 diets: basal diet (BD), BD plus 2.5 and 5.0% sunflower oil (SO) or tallow (T) at vitamin D provided $1{\times}$ and $3{\times}$ of the current recommendation. The experiment lasted from week 30 to 44 of age. Each diet was tested in 12 replicate cages of 4 hens. Production, metabolism, and egg quality data were subjected to three-way ANOVA. Both fats decreased feed intake (FI) as compared to BD. Increasing SO and T levels linearly decreased and quadratically increased FI, respectively. The dietary factors did not affect egg production (EP) and egg weight. Vitamin D supplementation increased and decreased EP when diets contained SO and T, respectively. Feed conversion efficiency (FCE) for hens fed SO was lower than for hens fed T. However, increasing T level improved FCE, whereas increasing SO level worsened FCR. Vitamin D supplementation increased serum vitamin D and glucose concentrations. Vitamin D supplementation also caused a decrease and an increase in serum vitamin D concentration when diets contained SO and T, respectively. Serum glucose concentration for hens fed SO was lower than hens fed T. Increasing fat level linearly increased serum triglyceride and VLDL concentrations, regardless of the fat type. Increasing SO level linearly decreased serum cholesterol concentration. Vitamin D supplementation did not alter lipid metabolites. The dietary factors did not affect serum total protein, Ca, and P concentrations. As compared with BD, feeding SO decreased dry tibia and ash weights more than feeding T. Vitamin D supplementation tended to increase dry tibia weight and decrease tibia ash weight. Eggshell strength and thickness, yolk and albumen indexes, and Haugh unit were not responsive to the dietary factors. Eggshell strength quadratically increased with increasing T level. Yolk color for hens fed SO was lower than for hens fed T. The dietary factors did not affect most of yolk fatty acids. Increasing SO level quadratically decreased yolk $C_{18:2}$ concentration. Vitamin D supplementation increased and decreased yolk $C_{18:2}$ concentration when diets contained SO and T, respectively. In conclusion, increasing fat level improved laying performance without altering metabolic profile and egg quality. Vitamin D supplementation had minor alteration effects on laying performance, metabolic profile, and egg quality in response to fat feeding.

• Journal of Korea Water Resources Association
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• v.42 no.9
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• pp.747-758
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• 2009

In this study, long-term variabilities of rainfall-occurrence characteristics are analyzed using rainfall data at Seoul, which is the longest data record existing in world. first, the accuracy of Chukwooki data set (CWK) are evaluated in view of rainfall-occurrence probability by analyzing the transition probabilities and occurrence characteristics based on Markov chain. And long-term inter-monthly variabilities of transition probabilities are analyzed using two dimensional LOWESS regression. From the results of analyzed transition probabilities and occurrence characteristics, it is different that rainfall-occurrence characteristics between CWK and modern rain gage data set (MRG) for original rainfall data sets (M00). For characteristics of rainfall series, occurrences probabilities of rainfall are increased and durations of each rainfall are shorter than past. And from the results of analyzing the long-term inter-monthly variabilities of transition probabilities, in case of M20, lengths of dry spells between CWK and MRG are not different significantly and lengths of wet spells are decreased persistently after A.D. 1830. Especially, decreasing trend for lengths of wet spells at recent september are appeared significantly. These results are considered with increasing trend of recent rainfall, it is concluded that recent frequencies and intensities of rainfall are increasing.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6788-6798
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• 2015

In recent high speed rail way, the operating speed of train is enhanced and the introduction of EMU train vehicles is increased. In addition, as expected the demand of the concrete slab track and the trend of design cross-section reduction, the clear behavior of evaluation of internal slab layer is demanded about the variation of design load and speed. The purpose of this study is to evaluate and identify the mechanical behavior pattern of concrete slab track and track-road bed with the variation of axle load and train speed. To this end, the behavior of TCL and HSB was evaluated in according to the variation of axle load and speed. And the analysis results and the data measured TCL strain sensor, which was embedded in TCL slab under installation on Honam high speed railway, was analyzed. The analysis result shows that the strain are increasing in according to the speed-up of train, and line regression was obtained from measured data. Analysis data of the state of bonding condition of slab layer and measured data was analyzed. It is conducted that the TCL layer stress of HEMU 430X, which of axle load, is lighter was similar to the stress of KTX-Honam, the standard deviation of measured stress is dramatically increased.

• Korean Journal of Psychosomatic Medicine
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• v.19 no.1
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• pp.41-47
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• 2011

Objective: Hyperprolactinemia is common side effect associated with antipsychotics use. Nevertheless, hyperprolactinemia is relatively neglected by clinician. Especially, there is no study related to amisulprideinduced hyperprolactinemia in korea. This study aimed to determine whether amisulpride can be induced hyperprolactinemia in Korean psychiatric patients. Methods: This study methodology consisted of a retrospective review of medical charts and prolactin levels. Serum prolactin levels were measured in 24 Korean patients(12 males and 12 females) with psychosis who were treated over 400mg of amisulpride per day. Results: All patients had hyperprolactinemia. Prolactin levels significantly increased after receiving amisulpride(z=-3.702, p=0.000). The prolactin level was significantly higher in females($156.29{\pm}63.75$ng/mL) than in males($69.04{\pm}39.91$ng/mL) after administering amisulpride(p=0.000). There was a correlation between dosage and prolactin levels(r=0.61, p=0.002). However, there was no correlation between duration of treatment and prolactin levels. Conclusions: Antipsychotics, especially amisulpride can increase serum prolactin levels and may results in short and long term side effects. Routine clinical assessment of initial and additional prolactin level and associated symptoms should be done

• Analytical Science and Technology
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• v.25 no.1
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• pp.19-24
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• 2012

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the quantitative determination of ertapenem in human plasma and urine. After addition of internal standard (ceftazidime), plasma and urine was diluted with methanol and analyzed by LC-MS/MS. Using MS/MS with multiple reaction monitoring (MRM) mode, ertapenem were selectively detected without severeinterference from human plasma and urine. The standard calibration curve for ertapenem was linear ($r^2$= 0.9996)over the concentration range 1~100 ${\mu}g/mL$ in human plasma. The intra- and inter-day precision over the concentration range of ertapenem was lower than 8.9% (correlation of variance, CV), and accuracy was between 97.2~106.2%. On the other hand, it was showed good relationship ($r^2$= 0.9992) and the precision (intra- and inter-day) over the concentration range of ertapenem was lower than CV 7.2%, and accuracy was between 97.9~111.6% for urine. This method has been successfully applied to the pharmacokinetic study of ertapenem in human plasma and urine.