• Korean Journal of Food Science and Technology
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• v.31 no.2
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• pp.509-515
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• 1999

Lactic acid bacteria (LAB) fermented foods were prepared from egg white powder (EWP), casein and growth stimulating agents (GSA). The effects of GSA on acid production and growth of Lactobacillus were studied. The effects of GSA on sensory properties and viscosity of LAB fermented foods were also studied. Acid production by Lactobacillus was stimulated by addition of GSA (0.3% or 1%, W/V). Although stimulating effect differed among each GSA, some GSA increased the acidity up to the level of fermented milk. However, stimulating effect of GSA on viable cells was not noticeable. Acid production by L. acidophilus was generally higher than other Lactobacilli. The optimum concentration of GSA added to substrate was 1% (W/V). Sensory evaluation showed that the optimum fermentation time was 18hr. The sensory properties of GSA samples were evaluated as slightly lower than that of fermented milk because GSA samples showed whey separation and taste and smell of GSA. Apparent viscosity of GSA samples was significantly lower than that of fermented milk and control sample (p<0.05). There was no significant difference of apparent viscosity among GSA samples. GSA samples, fermented milk and control sample showed thixotropic flow characteristics.

• The Korean Journal of Nuclear Medicine
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• v.32 no.4
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• pp.305-313
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• 1998

The reduction in the amount of asialoglycoprotein (ASGP) receptor, which resides exclusively on the plasma membrane of functioning mammalian hepatocytes, as a consequence of hepato-cellular damage has been demonstrated in various pathologic conditions of the liver. Galac-tosylated human serum albumin (GSA) is a newly developed receptor-binding agent, specific for the ASGP receptor. Tc-99m GSA binds quantitatively to liver ASGP receptors and the rate of accumulation in the liver is dependent on hepatic function represented as the amount of receptor, as well as the amount of ligand injected, its affinity to the receptor and the hepatic blood flow. The findings of Tc-99m GSA scintigraphy were reported to reflect the hepatic function of the patients with large hepatic tumors, obstructive jaundice, acute and chronic liver disease. Tc-99m GSA scintigraphy is an easy and reliable test and has the clinical potentials to evaluate the liver function in the patients with hepatic disorders.

• Genomics & Informatics
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• v.10 no.2
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• pp.123-127
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• 2012

Gene set analysis (GSA) is useful in interpreting a genome-wide association study (GWAS) result in terms of biological mechanism. We compared the performance of two different GSA implementations that accept GWAS p-values of single nucleotide polymorphisms (SNPs) or gene-by-gene summaries thereof, GSA-SNP and i-GSEA4GWAS, under the same settings of inputs and parameters. GSA runs were made with two sets of p-values from a Korean type 2 diabetes mellitus GWAS study: 259,188 and 1,152,947 SNPs of the original and imputed genotype datasets, respectively. When Gene Ontology terms were used as gene sets, i-GSEA4GWAS produced 283 and 1,070 hits for the unimputed and imputed datasets, respectively. On the other hand, GSA-SNP reported 94 and 38 hits, respectively, for both datasets. Similar, but to a lesser degree, trends were observed with Kyoto Encyclopedia of Genes and Genomes (KEGG) gene sets as well. The huge number of hits by i-GSEA4GWAS for the imputed dataset was probably an artifact due to the scaling step in the algorithm. The decrease in hits by GSA-SNP for the imputed dataset may be due to the fact that it relies on Z-statistics, which is sensitive to variations in the background level of associations. Judicious evaluation of the GSA outcomes, perhaps based on multiple programs, is recommended.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.34 no.1
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• pp.98-105
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• 1989

The examination to find out how the activity of glutamine synthetase (GSA) develop in each wheat leaves during the growth period was carried out. GSA/g FW/leaf were very low at leaf differentiation stage and increased highly several times by unfolding and development of leaf, and declined deeply with the advance of senescence in each leaves. GSA/g FW/leaf were risen gradually from the every lower leaves to the every upper leaves, in consequence activity level and maximum peak per g fresh weight of 7th-flag leaves were two or three times higher than those at the 1st-4th leaves in all of 12 applied nitrogen treatments, thereupon. the highest activities per g fresh weight showed in the 8th leaves. GSA/g FW/leaf was shown two peaks in the 6th-flag leaves and one peak in 1st-4th leaves, respectively. GSA/g FW/leaf (except for senescence leaves) and GSA/plant were increased gradually to the infloresscence emerging stage and were shown the first maximum peak at 13 days before anthesis, then were declined rapidly. to the milk ripe stage (7 days after anthesis). and were shown the second maximum peak at the early dough ripe stage (22 days after anthesis) .

• Geomechanics and Engineering
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• v.18 no.5
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• pp.493-502
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• 2019

Internal stability is an important safety issue for levees, embankments, and other earthen structures. Since a large part of the world's population lives near oceans, lakes and rivers, floods resulting from breaching of dams can lead to devastating disasters with tremendous loss of life and property, especially in densely populated areas. There are some main factors that affect the internal stability of dams, levees and other earthen structures, such as the erodibility of the soil, the water velocity inside the soil mass and the geometry of the earthen structure, etc. Thus, the mechanism of internal erosion and stability of soils is very complicated and it is vital to investigate the assessment methods of internal stability of soils in embankment dams and their foundations. This paper presents an improved support vector machine (SVM) model to predict the internal stability of soils. The grid search algorithm (GSA) is employed to find the optimal parameters of SVM firstly, and then the cross - validation (CV) method is employed to estimate the classification accuracy of the GSA-SVM model. Two examples of internal stability of soils are presented to validate the predictive capability of the proposed GSA-SVM model. In addition to verify the effectiveness of the proposed GSA-SVM model, the predictions from the proposed GSA-SVM model were compared with those from the traditional back propagation neural network (BPNN) model. The results showed that the proposed GSA-SVM model is a feasible and efficient tool for assessing the internal stability of soils with high accuracy.

• The Korean Journal of Nuclear Medicine
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• v.37 no.4
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• pp.254-259
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• 2003

$^{99m}Tc-galactosyl$ human serum albumin (Tc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically present in the hepatocyte membrane. Because these receptors are decreased in hepatic parenchymal damage, the degree of Tc-GSA accumulation in the liver correlates with findings of liver function test. Hepatic images were performed with Tc-GSA in patients with acute hepatic dysfunction by Amantia Subjunquillea poisoning, and compared with these of liver ultrasonography (USG). Tc-GSA (185 MBq, 3 mg of GSA) was injected intravenously, and dynamic images were recorded for 30 minutes. Time-activity curves for the heart and liver were generated from regions of interest for the whole liver and precordium. Degree of hepatic uptake and clearance rate of Tc-GSA were generated by visual interpretation and semiquantitative analysis parameters (receptor index : LHL15 and index of blood clearance : HH15). Visual assessment of GSA scintigraphy revealed mildly decreased liver uptake in all of subjects. The mean LHL15 and HH15 were 0.886 and 0.621, graded as mild dysfunction in 2, and mild to moderate dysfunction in 1 subject. In contrast, liver USG showed no remarkable changes of hepatic parenchyme. Tc-GSA scintigraphy was considered as a useful imaging modality in the assessment of the hepatic dysfunction.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.36 no.6
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• pp.545-553
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• 1991

To find out the basic data for the possibility of agricultural utilization for GSA (Glutamine Synthetase Activity), the effect of nitrogen on the GSA in wheat leaf discs, the variation of GSA after light treatment and the comparative activity of GS during preservation were studied. The result of this study suggested that GSA could play an important and direct regulatory role in the nitrogen assimilation by wheat. During the growth stage of wheat its integral activity was found to closely match the organic nitrogen content. GS may therefore be the rate limiting enzyme in inorganic N assimilation. Moreover, integral GSA was closely correlated with grain yield and grain nitrogen. GSA could be suitable to utilize as a parameter for super type selection and an indicator for optimum nitrogen fertilization. Throughout the experiment, the contents of NO; were increased by N fertilization so that the NO; content was not attributable to change in the level of GSA. At investigation during dark-light transition of culture, no change in the level of GSA was observed until after 8-14 hours in the light treatment. And the level of GSA in wheat leaf discs during preservation at refrigerated storage $(-20^{\circ}C)$ was stable until 12 weeks, when its leaf discs were sampled with liquid nitrogen.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.32 no.2
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• pp.117-132
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• 2014

This paper had a purpose on analyzing result data from pan-sharpening, which have applied on the KOMPSAT-2 and -3 image. Particularly, the study focused on comparing each relative spectral response functions, which considers to cause color distortions of fused image. Two images from same time and location have been collected by KOMPSAT-2 and -3 to apply in the experiment. State-of-the-art algorithms of GIHS, GS1, GSA and GSA-CA were employed for analyzing the results in quantitatively and qualitatively. Following analysis of previous studies, GSA and GSA-CA methods resulted excellent quality in both of KOMPSAT-2/3 results, since they minimize spectral discordances between intensity and PAN image by the linear regression algorithm. It is notable that performances from KOMPSAT-2 and- 3 are not equal under same circumstances because of different spectral characteristics. In fact, KOMPSAT-2 is known as over-injection of low spatial resolution components of blue and green band, are greater than that of the PAN band. KOMPSAT-3, however, has been advanced in most of misperformances and weaknesses comparing from the KOMPSAT-2.

• Proceedings of the Korean Society of Crop Science Conference
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• 1987.06a
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• pp.54-55
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• 1987

• Journal of Korean Society for Atmospheric Environment
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• v.13 no.1
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• pp.41-49
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• 1997

Status of photochemical air pollution in the Greater Seoul Area (GSA) between 1990 and 1995 was assessed in terms of frequency distributions, number of days exceeding standards, average concentration and meteorological effects. In Seoul compared with other areas in Korea, daily maximum concentration was higher but average concentration was not so high due to lower daily minimum from April to October. The top 5th percentile was high especially in summer season. Average number of days exceeding 100 ppb at monitoring stations in GSA was highest in 1994, the hottest year, but it was only 4 days a year. Mean meteorological pattern of high ozone days could be summarized as low wind speeds, high temperatures, strong solar radiation, and low precipitation. Westerlies were more frequent on high ozone days and at Pangi station located in the eastside of GSA, both number of high ozone days and average concentration were high. Effect of precursor transport on the rise of ozone concentration was, however, not consistently important on the whole in GSA.