• Title/Summary/Keyword: GS

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Effect of Ground Corn as an Additive for Silages from Red Ginseng Residue (홍삼박 Silage 제조시 첨가제로서 분쇄옥수수의 효과)

  • Back, Seung-Hoon;Bea, Hyoung-Churl;Kim, Yong-Kook
    • Korean Journal of Agricultural Science
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    • v.32 no.2
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    • pp.205-214
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    • 2005
  • The purpose of this study was to investigate the effect of ground corn as an additive to ginseng residue silages. The silages were made with corn (CS), red ginseng (GS), red ginseng residue +0.5% ground corn (GS0.5), w/w bases, red ginseng residue+1.0% ground corn (GS1.0) and red ginseng residue+silage inoculant, lactic acid bacteria (GSL). The raw materials were cut only for corn forage in 2cm length. The ginseng residue without cutting were mixed without or with additives, ground corn and inoculant, and ensiled each into two 2,000ml glass bottles. The bottles with silages were stored at a dark place at room temperature and formented for 60 days. The crude protein contents were higher for all red ginseng silages as 17.7, 18.8, 18.3 and 17.8% for GS, GS0.5, GS1.0 and GSL than that of corn silage as 8.8% (p<0.05). The calcium content were higher in GS, GS0.5, GS1.0 and GSL as 0.99, 1.13, 0.99 and 1.03% than that in CS as 0.31% (p<0.05). The pH of silages fermented for 60 days was similar each other; CS, GS, GS0.5, GS1.0 and GSL as 3.8, 3.7, 3.3, 3.5 and 3.7, respectively. However the pH of GS0.5 was the lower than that of corn silage. The total concentration of volatile fatty acids were higher for CS as 87.3 mM/dl than those of GS, GS0.5, GS1.0 and GSL as 44.7, 37.8, 46.3 and 47.2 nM/dl. However, the percentage of lactic acid concentration of ginseng silages such as GS, GS0.5, GS1.0 and GSL, 60.2, 77.2, 83.4 and 77.3% was higher than that in CS, 53.7% (p<0.05). The in vivo dry matter digestibilities for 72hr fermentation was higher in ginseng silages (GS, GS0.5, GS1.0 and GSL as 76.5, 75.8, 72.9 and 77.3%, respetively) than that in for CS as 52.1% (p<0.05). It can be concluded that silage added with ground corn (GS0.5 and GS1.0) and lactic acid inoculant were high in its quality, and the GS0.5 can be suggested as a practical method for red ginseng residues silage making.

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Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+

  • Lopez, B.M.;Kang, H.S.;Kim, T.H.;Viterbo, V.S.;Kim, H.S.;Na, C.S.;Seo, K.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.5
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    • pp.640-645
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    • 2016
  • The objective of this study was to evaluate the present conventional selection program of a swine nucleus farm and compare it with a new selection strategy employing genomic enhanced breeding value (GEBV) as the selection criteria. The ZPLAN+ software was employed to calculate and compare the genetic gain, total cost, return and profit of each selection strategy. The first strategy reflected the current conventional breeding program, which was a progeny test system (CS). The second strategy was a selection scheme based strictly on genomic information (GS1). The third scenario was the same as GS1, but the selection by GEBV was further supplemented by the performance test (GS2). The last scenario was a mixture of genomic information and progeny tests (GS3). The results showed that the accuracy of the selection index of young boars of GS1 was 26% higher than that of CS. On the other hand, both GS2 and GS3 gave 31% higher accuracy than CS for young boars. The annual monetary genetic gain of GS1, GS2 and GS3 was 10%, 12%, and 11% higher, respectively, than that of CS. As expected, the discounted costs of genomic selection strategies were higher than those of CS. The costs of GS1, GS2 and GS3 were 35%, 73%, and 89% higher than those of CS, respectively, assuming a genotyping cost of $120. As a result, the discounted profit per animal of GS1 and GS2 was 8% and 2% higher, respectively, than that of CS while GS3 was 6% lower. Comparison among genomic breeding scenarios revealed that GS1 was more profitable than GS2 and GS3. The genomic selection schemes, especially GS1 and GS2, were clearly superior to the conventional scheme in terms of monetary genetic gain and profit.

Pharmacological Mechanism of Action of GS283 and GS386 on Human Platelet and Pig Coronary Artery (관상동맥이완과 혈소판응집에 대한 GS283과 GS386의 약리작용기전에 관한 연구)

  • CHANG, Ki Churl;LEE, Hoi Young;LEE, Goun Woo;KOO, Eui Bon;KANG, Young Jin;LEE, Young Soo
    • Biomolecules & Therapeutics
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    • v.5 no.3
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    • pp.239-245
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    • 1997
  • Trimetoquinol (TMQ) and its analogs are known to have thromboxane $A_2$ antagonistic action. We also reported that GS389, chemically similar to TMQ, has competitive antagonistic action in rat aorta and human platelets. In the present study, we investigated the pharmacological characteristics of GS283 and GS 386, analogs of GS389, using vascular smooth muscle, human platelets and rat brain homogenates. In isolated pig coronary artery (PCA), both of GS283 and GS386 relaxed U46619-contracted rings in concentration dependent manner. Pretreatment with several concentrations of GS283 and GS386 shifted the dose-response curves to the right, and reduced of maximum contration dose-dependently. Furthermore, GS283 and GS386 strongly inhibited $Ca^{2+}$ -induced contraction in the PCA. In human platelets, U46619- and A23187-induced platelet aggregation was inhibited by GS283 and GS386, concentration-dependently. Anti-platelet aggregation was related to the compound\`s ability to inhibit ATP release at each stimulation. In rat brain homogenates, receptor-binding assay resulted that both GS283 and GS386 have a relative affinity to $\alpha$-adrenergic receptor. Taken together. we concluded that the mechamism of action of GS283 and GS86 is not related with in TXA$_2$ receptor but concerned with calcium antagonistic action and a-blocking action.n.

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Modeling of metadata for agricultural and livestock food product (농축산물 식품 메타데이터 모델링)

  • Cho, Hyeeun;Kim, Dae-young
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.10a
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    • pp.475-478
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    • 2016
  • This paper deals with how to operate the metadata for agricultural and livestock food product through the GS1 Source which is a GS1 standard metadata service. We defines GS1 standard identifiers for identifying food product and explain the guidelines for the methods how to document with GS1 standard schema and how to query the metadata in the storage of GS1 Source.

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Trends in Development of Residential Fuel Cell System (건물용 연료전지 시스템 개발 현황)

  • Jun, Hee Kwon;Lee, Soo Jae;Lee, Dong Hwal;Choi, Choeng Hoon;Kim, Min Seok;Bae, Suck Jung
    • Prospectives of Industrial Chemistry
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    • v.14 no.2
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    • pp.10-25
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    • 2011
  • 지속적으로 증가하고 있는 에너지 수요에 대처하기 위해 신재생에너지 기술 확보를 위한 노력이 계속되고 있다. 연료전지는 풍력, 태양전지와는 달리 환경적 제약 없이 연속적인 에너지 공급이 가능하여 건물용 분산발전용으로 적합한 요건을 갖추고 있다. 최근 시작된 시범보급 사업으로 건물용 연료전지의 초기 시장 진출이 시작되었고 공공 기관 대체에너지의무화와 그린홈 보급사업 시행으로 시장 확대가 기대된다. 본 논문에서는 건물용 연료전지 시스템의 기본원리와 국내외 개발 동향에 대해 살펴보았으며 핵심부품에 대한 기술개발 현황에 대해 기술하였다.

Glucosylsphingosine Activates Serotonin Receptor 2a and 2b: Implication of a Novel Itch Signaling Pathway

  • Afzal, Ramsha;Shim, Won-Sik
    • Biomolecules & Therapeutics
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    • v.25 no.5
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    • pp.497-503
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    • 2017
  • Recent reports claimed that glucosylsphingosine (GS) is highly accumulated and specifically evoking itch-scratch responses in the skins of atopic dermatitis (AD) patients. However, it was unclear how GS can trigger itch-scratch responses, since there were no known molecular singling pathways revealed yet. In the present study, it was verified for the first time that GS can activate mouse serotonin receptor 2a (mHtr2a) and 2b (mHtr2b), but not 2c (mHtr2c) that are expressed in HEK293T cells. Specifically, effects of GS on all mouse serotonin receptor 2 subfamily were evaluated by calcium imaging techniques. The GS-induced intracellular calcium increase was dose-dependent, and antagonists such as ketanserin (Htr2a antagonist) and RS-127445 (Htr2b antagonist) significantly blocked the GS-induced responses. Moreover, the proposed GS-induced responses appear to be mediated by phospholipase C (PLC), since pretreatment of a PLC inhibitor U-73122 abolished the GS-induced responses. Additionally, the GS-induced calcium influx is probably mediated by endogenous TRPC ion channels in HEK293T cells, since pretreatment of SKF-96365, an inhibitor for TRPC, significantly suppressed GS-induced response. In conclusion, the present study revealed for the first time that GS can stimulate mHtr2a and mHtr2b to induce calcium influx, by utilizing PLC-dependent pathway afterwards. Considering that GS is regarded as a pruritogen in AD, the present study implicates a novel GS-induced itch signaling pathway.

Purification and Characterization of Glutamine synthetase of Klebsiella pneumoniae (Klebsiella pneumoniae가 생산하는 Glutamine synthetase의 정제 및 특성)

  • 차정학;이왕식;성하진
    • Microbiology and Biotechnology Letters
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    • v.19 no.3
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    • pp.259-264
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    • 1991
  • Glutamine synthetase (GS) of Kkbsiellu pmumonzae was purified and identified it's properties. It was determined to be composed of 12 identical subunits and it's molecular weight was about 600,000. It's optimum pH and temperature were identified as pH 7.0 and $37^{\circ}C$ respectively, and also there was no considerable variation of activity between pH 5 and 8. When GS was incubated at $57^{\circ}C$ for 10 min, it's activity was decreased to half of maximum activity. It was observed that K. pneumoniae has adenylylation-deadenylylation system which regulates activity of GS according to the quality and quantity of nitrogen source like GS of E. coli Also it's GS was very similar to that of E. coli. in structure deduced from the immunodiffuslon experiment using anti-E. coli GS antibody.

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ON πgs-CLOSED SETS IN TOPOLOGICAL SPACES

  • LEE, BU YOUNG;SHIN, SU-YOUNG;PARK, JIN HAN
    • Honam Mathematical Journal
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    • v.28 no.2
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    • pp.261-277
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    • 2006
  • In this paper a new class of sets called ${\pi}gs$-closed sets is introduced and its properties are studied. Further the notions of ${\pi}gs$-$T_{1/2}$ spaces and ${\pi}gs$-continuity are introduced.

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In Vitro Antibacterial Effect of the Combination of Galla rhois ethanol extracts and Sodium chlorate against Intramacrophage Brucella abortus

  • Cha, Chun-Nam;Hong, Il-Hwa;Yu, Eun-Ah;Park, Eun-Kee;Yoo, Chang-Yeol;Kim, Suk;Lee, Hu Jang
    • Journal of Food Hygiene and Safety
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    • v.29 no.1
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    • pp.67-72
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    • 2014
  • This study investigated the antibacterial effects of GR ethanol extracts (GRE), sodium chlorate (SC) and a combination of GRE and SC (GS) on Brucella abortus (B. abortus). The antibacterial activities of GRE, SC and GS towards B. abortus were evaluated by incubating B. abortus with GRE, SC and GS. Following treatment with GRE, SC and GS, B. abortus survival and intracellular proliferation in macrophages were monitored. In the cellular cytotoxicity assay, GRE, SC and GS are not cytotoxic at concentrations less than $400{\mu}g/ml$, 15 mM and 0.6GS (1 of GS, GRE $1,000{\mu}g/ml$ + SC 30 mM), respectively. The viability of B. abortus was markedly decreased in a dose-dependent manner in all treatment groups. In addition, B. abortus intracellular proliferation within macrophages was significantly reduced in cells treated with GRE ($400{\mu}g/mL$), SC (15 mM) and 0.5GS (GRE $500{\mu}g/mL$ + SC 15 mM) after 48 hr-incubation (GRE, p < 0.01; SC and 0.5GS, p < 0.001). Especially, in the treatment of GS, the synergistic effect of GRE and SC treatment on B. abortus in macrophage was observed. In conclusion, GS is useful as an antibacterial candidate against B. abortus, and can be applied in the field of meat and milk hygiene.