• Korean Journal of Remote Sensing
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• v.26 no.5
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• pp.527-536
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• 2010

This paper reports a reliable GRD (Ground Resolved Distance) measurement method of using natural targets instead of the method using artificial targets. For this, we developed an edge profile extraction technique suitable for natural targets. We demonstrated the accuracy and stability of this technique firstly by comparing GRD values generated by this technique visually inspected GRD values for artificial targets taken in laboratory environments. We then demonstrated the feasibility of GRD estimation from natural targets by comparing GRD values from natural targets to those from artificial targets using satellite images containing both artificial and natural targets. The GRDs measured from the proposed method were similar to the values from visual inspection and the GRDs measured from the natural targets were similar to the values from artificial targets. These results support our proposed method is able to measure reliable GRD from natural targets.

• Journal of the Korea Institute of Military Science and Technology
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• v.17 no.6
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• pp.793-799
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• 2014

EO GRD(Ground Resolved Distance) resolution of airborne EO/IR(Electro-Optical/Infrared) sensor is a critical factor in test and evaluation for EO sensor performance. We propose the laboratory measurement set-up for EO GRD by constructing optical collimator which includes integrated sphere, blackbody, equivalent 3-bar target and 6 DOF motion simulator. GRD is measured in the photographic imagery of bar targets by 3 different distances for 3 EO/IR sensors and the measured results were analyzed statistically. We found that at least 7 sheets of imagery are needed in order to obtain meaningful EO GRD. The result of statistical analysis shows that the distribution of the measured GRD is nearly symmetric about the average GRD, and the better imagery ratio above the average GRD is about 40~70%. Also from the best GRD analysis, it is estimated that the design goal for EO GRD should be 30% superior to the required GRD.

• Korean Journal of Remote Sensing
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• v.34 no.6_1
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• pp.905-923
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• 2018

In order to generate high-resolution products using UAV images, it is necessary to analyze the sharpness of the themselves measured through image analysis. When images that have unclear sharpness of UAV are used in the production, they can have a great influence on operations such as acquisition and mapping of accurate three-dimensional information using UAV. GRD (Ground Resolved Distance) has been used as an indicator of image clarity. GRD is defined as the minimum distance between two identifiable objects in an image and is used as a concept against the GSD (Ground Sampling Distance), which is a spatial sample interval. In this study, GRD is extracted by analyzing the edge target without visual analysis. In particular, GRD to GSD ratio (GRD/GSD), or GRD expressed in pixels, is used as an index for evaluation the relative image sharpness. In this paper, GRD is calculated by analyzing edge targets at various altitudes in various shooting environments using a rotary wing. Using GRD/GSD, it was possible to identify images whose sharpness was significantly lowered, and the appropriateness of the image as an image clarity index was confirmed.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.6
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• pp.148-160
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• 2012

The main purpose of this paper is to deliver a climate analysis and evaluation method based on GIS by using airborne LiDAR data and Biotop type map and to provide spatial information of climate analysis and evaluation based on Biotop type Map. At first stage, the area, slope, slope length, surface, wind corridor function and width, and obstacle factors were analyzed to obtain cold/fresh air production and wind corridor evaluation. In addition, climate evaluation was derived from those two results in the second stage. Airborne LiDAR data are useful in wind corridor analysis during the study. Correlation analysis results show that ColdAir_GRD grade was highly correlated with Surface_GRD (-0.967461139) and WindCorridor_ GRD was highly correlated with Function_GRD (-0.883883476) and Obstacle_GRD (-0.834057656). Climate Evaluation GRID was highly correlated with WindCorridor_GRD (0.927554516) than ColdAir_GRD (0.855051646). Visual validations of climate analysis and evaluation results were performed by using aerial ortho-photo image, which shows that the climate evaluation results were well related with in-situ condition. At the end, we applied climate analysis and evaluation by using Biotop map and airborne LiDAR data in Gwangmyung-Shiheung City, candidate for the Bogeumjari Housing District. The results show that the aerial percentile of the 1st Grade is 18.5%, 2nd Grade is 18.2%, 3rd Grade is 30.7%, 4th Grade is 25.2%, and 5th Grade is 7.4%. This study process provided both the spatial analysis and evaluation of climate information and statistics on behalf of each Biotop type.

• Journal of Radiation Protection and Research
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• v.31 no.4
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• pp.181-186
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• 2006

A radiophotoluminescent glass rod detector (GRD) system has recently become commercially available. We investigate the dosimetric properties of the GRD regarding the reproducibility of signal, dose linearity and energy dependence. The reproducibility of five measurements for 50 GRDs is presented by an average of one standard deviation of each GRD and it is ${\pm}1.2%$. It is found to be linear in response to doses of $^{60}Co$ beam in the range 0.5 to 50 Gy with a coefficient of linearity of 0.9998. The energy dependence of the GRD is determined by comparing the dose obtained using cylindrical chamber to that by using the GRD. The GRD response for each beam is normalized to the response for a $^{60}Co$ beam. The responses for 6 and 15 MV x-ray beams are within ${\pm}1.5%$ (1SD). The energy response of GRD for high-energy photon is almost the same as the energy dependence of LiF:Mg:Ti (TLD-100)and shows little energy dependence unlike p-type silicon diode detector. The GRDs have advantages over other detectors such diode detector, and TLD: linearity, reproducibility and energy dependency. It has been verified to be an effective device for small field dosimetry for stereotactic radiosurgery.

• Progress in Medical Physics
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• v.18 no.1
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• pp.13-19
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• 2007

The purpose of study Is to Investigate whether glass rod detector (GRD) would be suitable for dosimeter of radiotherapy units. A GRD Is used for the measurement of the ou4put factors and x-axis beam profiles from Gamma Knife. The output factors measured with GRD from the 14, 8 and 4mm collimators relative to the 18mm collimator are $0.980{\pm}0.013,\;0.949{\pm}0.013\;and\;0.872{\pm}0.012$, respectively. The output factors obtained with a GRD are within 1.0% In good agreement with the values recommended by the manufacture. The full width at half maximum (FWHM) of x-axis beam profiles measured with GRD are 5.9mm at a 4mm collimator.

• Journal of Ginseng Research
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• v.41 no.4
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• pp.602-607
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• 2017

Background: Panax ginseng is a traditional herb used for medicinal purposes in eastern Asia. P. ginseng contains various ginsenosides with pharmacological effects. In this study, floralginsenoside A (FGA), ginsenoside Rd (GRD), and ginsenoside Re (GRE) were purified from P. ginseng berry. Methods: Chemical structures of FGA, GRD, and GRE were determined based on spectroscopic methods, including fast atom bombardment mass spectroscopy, ID-nuclear magnetic resonance, and infrared spectroscopy. Inhibitory activities of these compounds on melanogenesis were studied by measuring the expression of protein and melanin content in the melan-a cell line. This inhibitory activity was confirmed by observing pigmentation and tyrosinase activities of zebrafish. Results: GRD, GRE, and FGA were not cytotoxic at concentrations less than $20{\mu}M$, $80{\mu}M$, and $160{\mu}M$ in melan-a cells, respectively. GRD, GRE, and FGA inhibited melanin biosynthesis in melan-a cells by 15.2%, 22.9%, and 23.9% at $20{\mu}M$, $80{\mu}M$, and $160{\mu}M$, respectively. FGA was observed to display the most potent inhibitory effect. In addition, FGA decreased microphthalmia-associated transcription factor protein expression in a dose-dependent manner. Moreover, FGA induced extracellular signal-regulated kinase phosphorylation level in melan-a cells. In addition, melanin pigment content and tyrosinase activity in zebrafish treated with FGA at $160{\mu}M$ were reduced. Conclusion: FGA showed the most potent inhibition of melanogenesis in both in vitro and in vivo studies. This study suggests that FGA purified from P. ginseng may be an effective melanogenesis inhibitor.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.658-666
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• 2005

시멘트밀크(저압이나 고압에 의한 선단확근말뚝공법)나 쏘일시멘트(SIP말뚝공법) 위에 안치된 말뚝기초의 선단지지력과 확대기초를 지지하는 시멘트밀크 고결체 기둥 기초의 연직지지력 공식을 알아보기 위하여 총 14개의 시험체에 대하여 정재하시험 및 하중전이시험을 실시하였다. 그 결과에 의하면, 고결체 주변지반의 구속효과가 없는 8개의 시험체는 말뚝선단보강형태와는 무관하게 말뚝선단 아래의 시멘트밀크 고결체의 강도와 면적이 클수록 크게 나타났으며, 평균구속계수는 자유표면의 영향으로 1 보다 적은 0.43(D+1)이었다. 그리고 고결체 주변지반의 구속효과를 받는 6가지 지반조건에서 설치된 말뚝의 구속계수는 말뚝선단 아래 시멘트밀크 고결체를 주변지반의 구속효과로 1 보다 큰 평균 2.1의 값을 나타내었다. 그리고 지반의 구속효과를 고려한 말뚝기초와 직접기초 아래에 설치된 시멘트밀크 고결체의 이론적인 (선단)지지력 공식을 제안하였다.

• Journal of Ginseng Research
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• v.26 no.3
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• pp.139-144
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• 2002

Pregnancy is a physiological state accompained by a high energy demand of many bodily functions and an increased oxygen requirement. Because of the increased intake and utilization of oxygen, increased levels of oxidative stress would be expected. So we observed the activities of the hepatic antioxidant enzymes from rat treated with total saponin from the red ginseng against free raicals produced in pregnant rats. The activity of superoxide dismutase (SOD) in the control group was slightly decreased during pregnancy, and SOD activity in total saponin treated group was not observed any siginificant change compared with the control group. The activities of glutathione peroxidase (GPX), glutathione reductase (GRD) and catalase in the control group have shown the decreasing tendency during pregnancy, whereas the activities of GRD and catalase in total saponin treated group showed significant increased tendency compared with the control group. GPX activity in total saponin treated group was slightly decreased tendnency compared with the control group. The activity of glutathione-S-transferase (GST) in the control group was increased to keep the state of homaeostasis tendency in pregnant rats. On the other hand, the activity of GST after total saponin treatment was increased than control group. Activity of all enzymes in the control group and total saponin treated group recovered the normal level after delivery of rats. In spite of the physiological changes in vivo, the inflaunce of total saponin on activaties of hepatic antioxidant enzyme in pregnant rats seems to be regulated the biological homeostatic adaptation mechanism which protects the maternal liver aganist oxygen induced toxicity

• Progress in Medical Physics
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• v.24 no.2
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• pp.92-98
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• 2013

The experimental verification of treatment planning on the treatment spot is the ultimate method to assure quality of radiotherapy, so in-vivo skin dose measurement is the essential procedure to confirm treatment dose. In this study, glass rod dosimeter (GRD), which is a kind of photo-luminescent based dosimeters, was studied to produce a guideline to use GRDs in vivo dosimetry for quality assurance of radiotherapy. The pre-processing procedure is essential to use GRDs. This is a heating operation for stabilization. Two kinds of pre-processing methods are recommended by manufacturer: a heating method (70 degree, 30 minutes) and a waiting method (room temperature, 24 hours). We equally irradiated 1.0 Gy to 20 GRD elements, and then different preprocessing were performed to 10 GRDs each. In heating method, reading deviation of GRDs at same time were relatively high, but the deviation was very low as time went on. In waiting method, the deviation among GRDs was low, but the deviation was relatively high as time went on. The meaningful difference was found between mean reading values of two pre-processing methods. Both methods present mean dose deviation under 5%, but the relatively high effect by reading time was observed in waiting method. Finally, GRD is best to perform in-vivo dosimetry in the viewpoint of accuracy and efficiency, and the understanding of how pre-processing affect the accuracy is asked to perform most accurate in-vivo dosimetry. The further study is asked to acquire more stable accuracy in spite of different irradiation conditions for GRD usage.