• Title/Summary/Keyword: GP

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Effects of peripartal glucose precursor supplementation on lactation performance and metabolic health of primiparous and multiparous dairy cows

  • Muhammad Uzair Akhtar;Hifzulrahman;Talat Naseer Pasha;Muhammad Avais;Nauman Khan;Ghazanfar Ali Chishti;Mubashar Ali;Muhammad Imran;Muhammad Naeem Tahir;Muhammad Naveed-ul-Haque
    • Animal Bioscience
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    • v.36 no.6
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    • pp.869-878
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    • 2023
  • Objective: Hyperketonemia remains a major metabolic issue of serious milk production and a major health concern in early lactation cows. Oral supplementation of glucose precursors (GP) can be used to prevent hyperketonemia in dairy cows. The objective of this study was to compare the beneficial effects of orally supplementing a mixture of GP on metabolic health indicators and milk production status of primiparous (PP) and multiparous (MP) dairy cows. Methods: Twenty-eight Holstein cows were blocked by expected date of parturition, previous lactation yield, and parity. The cows were randomly allocated to one of the four treatment groups (n = 7 cows/group) based on their parity and GP supplementation: i) PP cows fed basal diet only (PP-CON), ii) PP cows with oral supplementation of GP (PP-GP), iii) MP cows fed basal diet only (MP-CON), and iv) MP cows with oral supplementation of GP (MP-GP). Glucose precursor (glycoline liquid) was orally drenched (300 mL/d) in GP cows from 7 days prepartum through 7 days postpartum. Other than GP supplementation, all cows were fed similar pre- and postpartum basal diets. Results: In both pre- and postpartum periods, serum glucose concentration was increased, whereas β-hydroxybutyrate and free fatty acids were decreased in GP cows compared with the CON cows. Milk yield and milk components were statistically not different between GP and CON cows over the first 9 week of lactation. The yield of actual milk, energy-corrected milk, 63-days cumulative milk, colostrum yield, and calf birth weight remained higher in MP cows compared with PP cows. Conclusion: Oral drenching of GP around calving can be recommended to successfully improve the metabolic health and reduce the negative effects of hyperketonemia not only in MP but also in PP dairy cows.

Analysis on the AIS functioning effect by the internal GPS (내부 GPS가 AIS 작동에 미치는 영향 분석)

  • Kim, Byungok
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2015.07a
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    • pp.293-295
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    • 2015
  • AIS의 내부 GPS는 UTC 동기 설정에 사용되며, AIS가 내부 GPS에 직접적으로 동기를 맞추지 못하면 직접동기를 하고 있는 주변 기지국 또는 선박국에 간접동기를 맞추도록 되어 있다. 그러나 내부 GPS 수신 상태가 불량하거나 GPS 접속 설정이 잘못된 경우 미송신이 발생하거나 잘못된 동적정보를 제공하는 등 AIS 동작에 오류가 발생하고 있다. 여기에서는 내부 GPS가 불량할 경우 AIS 작동에 어떤 영향을 미치는지 분석하였다.

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SOME RESULTS ON INTUITIONISTIC FUZZY TOPOLOGICAL SPACES DEFINED BY INTUITIONISTIC GRADATION OF OPENNESS

  • MIN WON KEUN;PARK CHUN-KEE
    • Communications of the Korean Mathematical Society
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    • v.20 no.4
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    • pp.791-801
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    • 2005
  • In this paper, we introduce the concepts of closure and interior defined by an intuitionistic gradation of openness. We also introduce the concepts of weakly gp-maps, gp-open maps and several types of compactness, and obtain some characterizations.

SOME RESULTS ON AN INTUITIONISTIC FUZZY TOPOLOGICAL SPACE

  • Min, Kyung-Ho;Min, Won Keun;Park, Chun-Kee
    • Korean Journal of Mathematics
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    • v.14 no.1
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    • pp.57-64
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    • 2006
  • In this paper, we introduce the concepts of $r$-closure and $r$-interior defined by intuitionistic gradation of openness. We also introduce the concepts of $r$-gp-maps, weakly $r$-gp-maps, and obtain some characterizations in terms of $r$-closure and $r$-interior operators.

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RESULTS ON AN INTUITIONISTIC FUZZY TOPOLOGICAL SPACE

  • Min, Won-Keun;Min, Kyung-Ho;Park, Chun-Kee
    • The Pure and Applied Mathematics
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    • v.14 no.2 s.36
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    • pp.63-70
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    • 2007
  • In this paper, we introduce the concepts of r-gp-open map, weakly r-gp-open map, intuitionistic fuzzy r-compactness, nearly intuitionistic fuzzy r-compactness and almost intuitionistic fuzzy r-compactness defined by intuitionixtic gradations of openness, and obtain some characterizations.

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Effect of Granite Porphyry Supplementation on Growth Performance and Meat Sensory Quality in Broiler Chickens (맥반석의 첨가 급여가 육계에서 성장성적 및 관능적 특성에 미치는 영향)

  • Choi T. H.;Kim D. W.;Ahn S. M.;You S. J.;Kim S. K.;An B. K.;Kang C. W.
    • Korean Journal of Poultry Science
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    • v.31 no.3
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    • pp.151-155
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    • 2004
  • This experiment was conducted to investigate the influence of dietary supplementation of granite porphyry (GP) on growth performances and meat sensory quality in commercial broiler chicks. A total of four hundred-fifty 5-day-old male broiler chicks were divided into 15 pens and fed one of five experimental diets for 5 weeks; 0% GP with antibiotics (Control), 1% GP with or without antibiotics, and 2% GP with or without antibiotics. Final body weight and daily weight gain of all GP supplemented groups were slightly higher than those of control. Feed conversion rate was improved in GP 1 % supplemented groups, although there was no significant difference. Feeding antibiotics in addition to GP did not influence the growth parameters. Relative weights of liver and abdominal fat tended to be reduced in broiler chickens fed GP supplemented diets. Feeding of 2% GP diet resulted in a significant improvement in meat sensory quality in terms of taste and tenderness(P < 0.05), but the effect of the 1% GP on meat sensory quality was not significant. The results of this study indicate that GP could be used as a favorable feed additive for production of sensory-enhanced broiler meats.

Effect of $\beta_2$-GP1 on the Binding of Anti-cardiolipin Antibodies to Cardiolipin (Anti-cardiolipin 항체와 Cardiolipin의 결합에 미치는 $\beta_2$-GP1의 영향)

  • Kang, Eun-Young;Jang, Young-Ju
    • IMMUNE NETWORK
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    • v.4 no.3
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    • pp.161-165
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    • 2004
  • Background: Anti-cardiolipin antibody (Anti-CL Ab) is one of the various antiphospholipid antibodies (Anti-PL Abs) and found in the plasma of patients with systemic lupus erythematosus (SLE), atherosclerosis, and other infectious diseases. While anti-PL Abs found in the sera of patients with infectious diseases bind directly to CL, binding of anti-PL Abs to CL circulating in the sera of patients with autoimmune diseases is mediated by $\beta_2-$glycoprotein 1 ($\beta_2-GP1$). The purpose of this study is to investigate the effect of <$\beta_2-GP1$ on the antigen binding assay of anti-CL Abs present in the sera of patients with atherosclerosis, which has been known as one of autoimmune diseases. Methods: ELISA was performed with sera containing anti-CL Abs from three patients with atherosclerosis in the presence or absence of $\beta_2-GP1$ or FBS. Results: Reactivity of anti-CL Abs to CL was increased in the presence of $\beta_2-GP1$ or FBS in a dose dependent manner. Conclusion: <$\beta_2-GP1$ or FBS could be used as co-factor in CL ELISA with anti-CL Abs present in the sera of patients with atherosclerosis. It is suggested that anti-CL Abs found in atherosclerosis patients are similar in terms of antigen binding property to those circulating in the patients with autoimmune diseases, not to infectious diseases.

Scouring Effect of PAPE(Polyoxyethylene Alkyl Phosphoric Ester) on Cotton Fibres (면섬유에 대한 폴리옥시에틸렌 알킬 인산에스테르의 정련효과)

  • Ha, Youn-Shick;Kwak, Gyeong-Do;Chang, Yoon-Ho
    • Applied Chemistry for Engineering
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    • v.10 no.7
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    • pp.974-978
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    • 1999
  • This study was concerned with the scouring effect of anionic surfactants, PAPE(sodium polyoxyethylene alkyl phosphoric ester) for cotton fibres. Sodium polyoxyethylene(7) nonylphenyl phosphoric ester(CPB-1) and the sodium polyoxyethylene(7) tridecyl phosphoric ester(CPB-2) were synthesized by the phosphoric esterification reaction from NP-7(polyoxyethylene(7) nonylphenyl ether) and TDA-7(polyoxyethylene(7) tridecyl ether) as scouring agents. Defoaming ability, fibre wetting time and absorbency rate of scouring agents were investigated. Being compared with the conventional scouring agent(Ultravon GP; Ciba-guyge Co.), CPB-1 and CPB-2 showed a higher defoaming ability in the cotton scouring process at room temperature. And CPB-1 has a higher wetting effect than the agents, CPB-2 or GP in distilled water bath but CPB-2 showed more scouring effect in 1.2 wt % NaOH solution bath.

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Gecko Proteins Exert Anti-Tumor Effect against Cervical Cancer Cells Via PI3-Kinase/Akt Pathway

  • Jeong, Ae-Jin;Chung, Chung-Nam;Kim, Hye-Jin;Bae, Kil-Soo;Choi, Song;Jun, Woo-Jin;Shim, Sang-In;Kang, Tae-Hong;Leem, Sun-Hee;Chung, Jin-Woong
    • The Korean Journal of Physiology and Pharmacology
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    • v.16 no.5
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    • pp.361-365
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    • 2012
  • Anti-tumor activity of the proteins from Gecko (GP) on cervical cancer cells, and its signaling mechanisms were assessed by viable cell counting, propidium iodide (PI) staining, and Western blot analysis. GP induced the cell death of HeLa cells in a dose-dependent manner while it did not affect the viability of normal cells. Western blot analysis showed that GP decreased the activation of Akt, and co-administration of GP and Akt inhibitors synergistically exerted anti-tumor activities on HeLa cells, suggesting the involvement of PI3-kinase/Akt pathway in GP-induced cell death of the cancer cells. Indeed, the cytotoxic effect of GP against HeLa cells was inhibited by overexpression of constituvely active form of Akt in HeLa cells. The candidates of the functional proteins in GP were analyzed by Mass-spectrum. Taken together, our results suggest that GP elicits anti-tumor activity against HeLa cells by inhibition of PI3-kinase/Akt pathway.

Effect of glass powder on the behaviour of high performance concrete at elevated temperatures

  • Kadik, Abdenour;Cherrak, Messaouda;Bali, Abderrahim;Boutchicha, Djilali;Hannawi, Kinda
    • Advances in concrete construction
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    • v.10 no.5
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    • pp.443-454
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    • 2020
  • In recent years, many studies have been done on the performance of concrete containing glass powder (GP). For the purpose of widespread use of GP in concrete mixes, a knowledge of the performance of such a mixture after a fire is essential for the perspective of structural use. This research work was carried out to evaluate the performance of High Performance Concrete (HPC) made with GP after being exposed to elevated temperature. The studied mixtures include partial replacement of cement by GP with up to 30%. The mechanical performance and structural alterations were assessed after high temperature treatment from 200℃ to 800℃. The mechanical performance was evaluated by testing the specimens to the compressive and tensile strength. In addition, the mass loss and the porosity were measured to notice the structural alterations. Changes in microstructure due to temperature was also investigated by the X-ray diffraction (XRD) and thermal gravimetric analyses (TGA) as well as porosity adsorption tests. The results of the concrete strength tests showed a slight difference in compressive strength and the same tensile strength performance when replacing a part of the cement by GP. However, after high temperature exposition, concrete with GP showed better performance than the reference concrete for temperature below 600℃. But, after heating at 800℃, the strength of the concrete with GP drop slightly more than reference concrete. This is accompanied by an important increase in mass loss and water porosity. After the microstructure analysis, no important changes happened differently for concrete with GP at high temperature except a new calcium silica form appears after the 800℃ heating.