• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.2
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• pp.350-358
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• 1998

The antimutagenic and anticancer activities of glycoprotein(GP) and chondroitin sulfate(CS) from sea cucumbers were studied using Ames mutagenicity test and human cancer cells culture test. The GP's inhibitory effect toward aflatoxin B1(AFB1) and 3, 2'-dimethyl-4-amino-biphenyl(DMAB) increased with the higher added concentrations up to 5% level(w/w) regardless fractionation methods. The GP from sea cucumbers through DEAE-cellulose column chromatography showed an inhibitory effect ranged from 84 to 98%, and the maximum antimutagenicities resulted in red sea cucumber with 98% (AFB1) and 95% (DMAB). But 5% level of CS from various sea cucumbers had an inhibitory effect toward those both indirect mutagens ranged from 79% to 85%. However, in case of direct mutagens(N-methyl-N'-nitro-N-nitrosoguanidine, MNNG and 4-nitroquinoline-1-oxide, 4-NQO), the GP's inhibitory effect was 55∼78% and the CS had a low inhibitory effect(58∼70%) at the added level of 5%. The GP from sea cucumbers exhibited the strong inhibitory effects with 89∼95% and 82∼92% on the growth of HT-29 human crcinoma cells and AZ-521 human gastric cancer cells (at 5% level).

• Journal of the Korean Institute of Intelligent Systems
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• v.20 no.5
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• pp.603-609
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• 2010

This paper introduces an objects recognition algorithm based on SURF(Speeded Up Robust Features) and GP(Genetic Programming) based gaits generation. Combining both methods, a recognition based intelligent walking for quadruped robots is proposed. The gait of quadruped robots is generated by means of symbolic regression for each joint trajectories using GP. A position and size of target object are recognized by SURF which enables high speed feature extraction, and then the distance to the object is calculated. Experiments for objects recognition and autonomous walking for quadruped robots are executed for ODE based Webots simulation and real robot.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.573-575
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• 2015

Positioning system using satellite GPS is used at positioning, navigation, acquisition time information and other various field and taking an important part precision guided weapon such as missile. But commercial code(C/A code) do not have ECCM. Therefore commercial code is vulnerable to various jamming techniques and noise jamming from near station can attack even the encrypted military code(P code) GPS. In this paper, GPS jamming techniques, North Korean GPS jamming cases and anti-jamming GP S technologies are surveyed and described.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.12
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• pp.1748-1755
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• 2015

A linear regression is widely used for prediction problem, but it is hard to manage an irregular nature of nonlinear system. Although nonlinear regression methods have been adopted, most of them are only fit to low and limited structure problem with small number of independent variables. However, real-world problem, such as weather prediction required complex nonlinear regression with large number of variables. GP(Genetic Programming) based evolutionary nonlinear regression method is an efficient approach to attach the challenging problem. This paper introduces the improvement of an GP based nonlinear regression method using ADF(Automatically Defined Function). It is believed ADFs allow the evolution of modular solutions and, consequently, improve the performance of the GP technique. The suggested ADF based GP nonlinear regression methods are compared with UM, MLR, and previous GP method for 3 days prediction of wind speed using MOS(Model Output Statistics) for partial South Korean regions. The UM and KLAPS data of 2007-2009, 2011-2013 years are used for experimentation.

• Journal of Pharmaceutical Investigation
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• v.34 no.2
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• pp.95-99
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• 2004

One mechanism which plays a prominent role in development of multi-drug resistance seen in cancer cells is the over-expression of P-glycoprotein (P-gp). It is known that compounds found in vegetables and fruits not only have anticarcinogenic properties but may also modulate P-gp activity. The effect of some dietary components on efflux of daunomycin (DNM), a P-gp substrate, was examined in P-gp over-expressed human uterine sarcoma cell line, MES-SA/DX5. The efflux of DNM from the cells was significantly inhibited by quercetin and verapamil, but not by 1-naphtyl-isothiocyanate (NITC). The $IC_{50}$ values for DNM in MES-SA/DX5 cells were increased by flavonoids (quercetin and fisetin), but not by NITC after 72 hour incubation with dietary constituents. In conclusion, flavonoids may play a role in the modulation of P­-gp activity in human uterine sarcoma cells.

• Journal of Ginseng Research
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• v.45 no.2
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• pp.211-217
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• 2021

The treatments of nervous system diseases (NSDs) have long been difficult issues for researchers because of their complexity of pathogenesis. With the advent of aging society, searching for effective treatments of NSDs has become a hot topic. Ginseng polysaccharides (GP), as the main biologically active substance in ginseng, has various biological properties in immune-regulation, anti-oxidant, anti-inflammation and etc. Considering the association between the effects of GP and the pathogenesis of neurological disorders, many related experiments have been conducted in recent years. In this paper, we reviewed previous studies about the effects and mechanisms of GP on diseases related to nervous system. We found GP play an ameliorative role on NSDs through the regulation of immune system, inflammatory response, oxidative damage and signaling pathway. Structure-activity relationship was also discussed and summarized. In addition, we provided new insights into GP as promising neuroprotective agent for its further development and utilization.

• Journal of the Korea Society of Computer and Information
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• v.28 no.2
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• pp.1-7
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• 2023

In this paper, we propose a base address candidate selection method using the $gp register and page granularity as a way to build a static analysis environment for firmware based on MIPS architecture. As a way to shorten the base address search time, which is a disadvantage of the base address candidate selection method through inductive reasoning in existing studies, this study proposes a method to perform page-level search based on the $gp register in the existing base address candidate selection method as a reference point for search. Then, based on the proposed method, a base address search tool is implemented and a static analysis environment is constructed to prove the validity of the target tool. The results show that the proposed method is faster than the existing candidate selection method through inductive reasoning.

• Korean Journal of Agricultural Science
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• v.50 no.3
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• pp.391-398
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• 2023

Garlic powder (GP) was supplemented in the diet to assess the growth efficiency, nutritional retention, and fecal score of growing pigs. In total, 80 growing pigs ([Yorkshire × Landrace] × Duroc) were arbitrarily allotted (22.04 ± 0.56 kg primary average body weight) to two different trial groups with eight repetitions (three males and two females) in each pen for the 42-day trial. The dietary treatment consisted of control (CON, basal diet), which included 0.2% GP (TRT1). Growing pigs fed the GP diet exhibited an increase (p < 0.05) in body weight on day 42 and a lower (p < 0.05) overall feed conversion ratio compared to the CON pigs; however, the average daily gain and feed intake showed no difference (p > 0.05). Additionally, nutrient utilization of dry matter was greater (p < 0.05) in the GP-supplemented diet group than in the CON group. The feeding methods did not adversely affect the nitrogen and energy utilization and the fecal score significantly (p > 0.05). In summary, growing pigs fed the GP diet showed increased growth and nutritional utilization, and no adverse impact on the fecal score; thus, it could be utilized as a stimulant for improved growth performance.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.1376-1379
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• 1996

In this paper a GPS receiver is developed using commercial chipsets. GP2010 RF front end and GP2021 Multi-channel correlator of GEC PLESSY are adapted in designing the receiver hardware. MC 68340 is used for controlling the correlator GP2021 and implementing the navigation processing. Also presented are some test results of the developed receiver whose software has an interrupt driven structure rather than common real-time kernel based structure.

• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 1999.12a
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• pp.52-58
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• 1999

본 연구에서는 국내의 항공사진측량에서 적용되지 않고 있는 광속조정 Program을 구현하였다. 또한, 구현된 프로그램을 이용하여 과천지역에 대한 측량자료를 처리하였다. GPS를 이용하여 결정한 카메라 노출중심 위치를 이용하여 광속조정에 적용한 결과는 지상기준점수가 감소하여도 정확도는 완만하게 저하되었으나, 지상기준점만을 이용하여 광속조정에 적용한 결과는 지상기준점수가 감소함에 따라 정확도는 급격하게 저하되었다. GPS를 이용하여 결정한 카메라 노출중심 위치를 광속조정에 적용한 결과 블록 가장자리에 배치한 4개의 지상기준점 만으로 공공측량에 적합한 결과를 얻을 수 있었다. 본 연구를 통하여 GPS로 결정한 카메라의 노출중심위치를 항공삼각측량에 적용할 경우 필요한 지상기준점수를 축소함으로써, 비용을 절감할 수 있을 것으로 판단된다.