• Toxicological Research
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• v.32 no.1
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• pp.35-46
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• 2016

No-flow ischemia occurs during cardiac arrest, hemorrhagic shock, liver resection and transplantation. Recovery of blood flow and normal physiological pH, however, irreversibly injures the liver and other tissues. Although the liver has the powerful machinery for mitochondrial quality control, a process called mitophagy, mitochondrial dysfunction and subsequent cell death occur after reperfusion. Growing evidence indicates that reperfusion impairs mitophagy, leading to mitochondrial dysfunction, defective oxidative phosphorylation, accumulation of toxic metabolites, energy loss and ultimately cell death. The importance of acetylation/deacetylation cycle in the mitochondria and mitophagy has recently gained attention. Emerging data suggest that sirtuins, enzymes deacetylating a variety of target proteins in cellular metabolism, survival and longevity, may also act as an autophagy modulator. This review highlights recent advances of our understanding of a mechanistic correlation between sirtuin 1, mitophagy and ischemic liver injury.

• 한국금형공학회:학술대회논문집
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• 2008.06a
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• pp.121-127
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• 2008

Nowdays CAE has been used for almost all injection molding designs in order to find the best injection conditions. Almost all CAE use 2-D mesh, but the CAE with 2-D mesh can't indicate such as jetting, flow-mark and filling imbalance in multi cavity mold. In this study, we suggested a new 3D meshing. the method which can indicate the filling imbalance in geometrically balanced runner system with Mold Flow MPI 6.1 and we found out that the calculation times are saved. As a feasibility study, we verified that Melt Flipper, RC Pin etc appeared the balanced filling behaviors. of geometrically balanced runner system and Melt Flipper, filling imbalance was indicated more accurately.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.6 s.171
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• pp.55-60
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• 2005

This paper has been focused in developing of plastic lens with ultra-precision and low birefringence ability using by injection molding simulation tools. The simulation tools, $3D-Timon^{TM}\;and\;Asu-Mold^{TM}$ were applied to visualize indirectly the flow pattern of melted polymer enter the mould and the simulation results are verified as compared with the experimental results. Birefringence and polarized light generated in injection molding process was also calculated for each injection conditions and compared with .the pictures of experimented optical lens go through the polarized light plates device. A spherical radius of plastic optical lens transcribed from profile of mould core surface was measured to estimate the geometrical accuracy fer the each injection conditions. It is confirmed that the simulation results about flow pattern and polarized light area coincided in experimental results. It is known that increasing in thickness shrinkage at center of lens, the spherical radius is larger from comparing the graph measured spherical radius and the thickness shrinkage at center of lens

• Asia pacific journal of information systems
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• v.32 no.2
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• pp.249-274
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• 2022

This study is to focuses on users' attitudes toward augmented reality games. Based on the Technology Acceptance Model (TAM) and Flow theory, continuous usage intention was set as a dependent variable, and immersion was set as a mediating variable. As independent variables, spatial presence, perceived interactivity, perceived pleasure, and sickness were set. Besides, this study strived to compare and analyze Korean and Chinese Data. The results of this study were as follows. First of all, Korean users significantly affected spatial presence, perceived pleasure, and immersion. Spatial presence and perceived pleasure had also mediated effects on continuous usage intention through immersion. However, perceived interactivity and sickness did not affect immersion and even no mediating effect to continuous usage intention. In the case of Chinese users, spatial presence, perceived interactivity, and perceived pleasure were grouped into one variable. This variable influenced immersion and also had mediated effect on continuous usage intention. However, sickness, like Korean users, did not affect the set path. This study had implications for analyzing user perspective using immersion, a significant variable in previous research. In addition, this study found similarities and characteristics through a comparative analysis between Korean and Chinese users indirectly.

• Journal of the Korea Society of Computer and Information
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• v.23 no.7
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• pp.105-111
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• 2018

Last March, the world Go competition between AlphaGo, AI Go program developed by Google Deep Mind and professional Go player Lee Sedol has shown us that the 4th industrial revolution using AI has come close. Especially, there ar many system combined with AI hae been developing including program for researching legal information, system for expecting jurisdiction, and processing big data, there is saying that even AI legal person is ready for its appearance. As legal field is mostly based on text-based document, such characteristic makes it easier to adopt artificial intelligence technology. When a legal person receives a case, the first thing to do is searching for legal information and judical precedent, which is the one of the strength of AI. It is very difficult for a human being to utilize a flow of legal knowledge and figures by analyzing them but for AI, this is nothing but a simple job. The ability of AI searching for regulation, precedent, and literature related to legal issue is way over our expectation. AI is evaluated to be able to review 1 billion pages of legal document per second and many people agree that lot of legal job will be replaced by AI. Along with development of AI service, legal service is becoming more advanced and if it devotes to ethical solving of legal issues, which is the final goal, not only the legal field but also it will help to gain nation's trust. If nations start to trust the legal service, it would never be completely replaced by AI. What is more, if it keeps offering advanced, ethical, and quick legal service, value of law devoting to the society will increase and finally, will make contribution to the nation. In this time where we have to compete with AI, we should try hard to increase value of traditional legal service provided by human. In the future, priority of good legal person will be his/her ability to use AI. The only field left to human will be understanding and recovering emotion of human caused by legal problem, which cannot be done by AI's controlling function. Then, what would be the attitude of legal people in this period? It would be to learn the new technology and applying in the field rather than going against it, this will be the way to survive in this new AI period.

• Economic and Environmental Geology
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• v.39 no.5 s.180
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• pp.615-626
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• 2006

The natural resources and material life-cycle include all human activities related to resources and material extraction, transportation, processing, use, recovery and disposal. Sustainable material management (SMM) is an integrated set of policy approaches targeted on economic agents throughout the material life-cycles and designed to result in economically efficient and environmentally effective material use. The material flows of industrial mineral, ores and fossil fuels have also long been a focal area for environmental policies because of the high environmental pressures associated with extraction, processing, consumption, and final disposal of these materials. OECD work on material flow is to improve the quantitative and analytical knowledge bases about natural resource and material flows within and among countries, so as to better understand the importance of material resources in member countries' economies. In several EU Member States, material flow accounts are part of official statistics. Material flow analysis (MFA) is a valuation method which assesses the efficiency of use of materials using information from material flow accounting. Material flow analysis helps to identify waste of natural resources and other materials in the economy which would otherwise go unnoticed in conventional economic monitoring systems. Resource use and resource efficiency has emerged as a major issue for long-term sustainability and environmental policy.

• Korean Journal of Construction Engineering and Management
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• v.1 no.2 s.2
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• pp.63-70
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• 2000

Since inorganic pigment, among admixtures used for cement composites, can raise the esthetic value of a building due to its effect of coloring, it can be assumed that the quantity consumed is expected to increase in connection with the recent trend of emphasizing the beautiful sights of the city. We carried out a flow test by changing the mix proportion of the cement mortar mixed with an inorganic pigment, water-cement ratio and pigment mixing ratio in order to present the basic materials for utilizing colored cement mortars. In construction by exploring the effect of inorganic pigments on the workability of cement mortar. In case of red pigment mortar and yellow pigment mortar, the workability was found to be rapidly decreased. To secure proper workability, it is necessary to increase the amount of mixing water, or to use superplasticizer. In case of green pigment mortar, however, it recorded $-2.4{\~}6.9{\%}$, showing that there was almost no change in flow. In case of black pigment mortar, it was also confirmed that there is no need to consider workability.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.12B
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• pp.1017-1027
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• 2006

Recently, Internet service providers are offering triple play service which combines voice and video services with the existing high speed Internet service under the common network infrastructure of IP protocol, so that they can create more benefit from operating a single network architecture. In line with this movement in the convergence of network and services, in this work we propose a bandwidth dimensioning method for the subscriber network of the IP network at flow level. To that purpose, let us propose a series of bandwidth dimensioning methods: bandwidth for best effort service only, bandwidth dimensioning for premium services, and bandwidth dimensioning schemes for the premium Internet services as well as the best effort service which comprise the TPS. Our link dimensioning method is based on the flow level that incorporates the flow blocking probability as a measure of grade of services(GoS), and investigates the characteristics of the proposed methods via extensive numerical experiments. After that, let us carry out a simulation experiment concerning the delay and loss performance of the packet scheduling for the premium services (QoS) using the bandwidth designed by our proposed method, via which the packet level quality of service (QoS) for the proposed link dimensioning method can be observed.

• Journal of the Korean Society of Clothing and Textiles
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• v.18 no.3
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• pp.387-394
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• 1994

Journal of the Korean Society of Clothing and Textiles Vol. 18, No. 3 (1994) p. 387∼394 In this study, the restriction of slacks (blue jean) versus box pleats skirt was investigated, from the view point of peripheral blood flow at the toe according to motion variation and E.M.G. analysis of leg muscles after walking on the flat or going up and down stairways. Besides, the pressure of slacks on the lower extrimity was measured statically and dynamically. The main results were summerized as follows; 1. The clothing pressure applied by slacks was; each one of thigh and lower leg was 18.2 g/ cm2 and 22.1 g/cm2 in upright, 63.4 g/cm2 and 26.6 g/cm2 in sitting on the chair, on both sides of thigh and lower leg 272.0 g/cm2 over in squatting. 2. When the motion starts from upright, the dynamic clothing pressure reach their peak before the motions end. When the motion ends and the body comes to a still condition, the clothing pressure grow lower and indicate a constant value. but when the body starts moving again to return to upright, the pressures once grow higher and go to zero value after reaching the peak. The pressure on the knee show much greater than those on the hip. This can be because these pressures depend on the degree of skin stretching motion and of its curvature. 3. The surface E.M.G. in leg muscles M. rectus femoris and M. gastrocnemius were recoreded. In the case of wearing slacks, two muscles were activated much more than wearing skirt. 4. The peripheral blood flow at the toe by wearing slacks was lower than wearing skirt. Also the case when squatting, the peripheral blood flow at the toe was low.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.8
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• pp.677-683
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• 2015

Hybrid rocket combustion displays low frequency instability(LFI, 10~30Hz) at a certain condition. Vortex shedding in the post-chamber is suspected to cause the occurrence of LFI. This study focused on the visualization of flow image using light emissions from high temperature combustion gas. Results shows that combustion pressure oscillates at a frequency of about 18 Hz, which is in phase with oscillations of light emission. Since LFI is not a property of thermo-acoustic instability, this result suggested there exists a physical coupling of pressure fluctuations with light emissions proportional to chemical reaction. Also POD analysis shows that dominant symmetric spatial modes in the stable combustion shift suddenly into asymmetric spatial pattern with the appearance of LFI. Especially, the appearance of mode 3 is a typical change of flow dynamics in unstable combustion representing a rotational fluid motions associated with vortex shedding.