• Title/Summary/Keyword: GLS

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Estimation of diesel fuel demand function using panel data (시도별 패널데이터를 이용한 경유제품 수요함수 추정)

  • Lim, Chansu
    • Journal of Energy Engineering
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    • v.26 no.2
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    • pp.80-92
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    • 2017
  • This paper attempts to estimate the diesel fuel demand function in Korea using panel data panel data of 16 major cities or provinces which consist of diesel demands, diesel market prices and gross value added from the year 1998 to 2015. I apply panel GLS(generalized least square) model, fixed effect model, random effect model and dynamic panel model to estimating the parameters of the diesel fuel demand function. The results show that short-run price elasticities of the diesel fuel demand are estimated to be -0.2146(panel GLS), -0.2886(fixed effect), -0.2854(random effect), -0.1905(dynamic panel) respectively. And short-run income elasticities of the diesel fuel demand are estimated to be 0.7379(panel GLS), 0.4119(fixed effect), 0.7260(random effect), 0.4166(dynamic panel) respectively. The short-run price and income elasticities explain that demand for diesel fuel is price- and income-inelastic. The long-run price and income elasticities are estimated to be -0.4784, 1.0461 by dynamic panel model, which means that demand for diesel fuel is price-inelastic but income-elastic in the long run. In addition I apply dummy variable model to estimate the effect of 16 major cities or provinces on diesel demands. The results show that diesel demands is affected 10 regions on the basis of Seoul.

The Effects of Ownership Concentration on Savings Bank Diversification by using Panel Data (패널데이터를 이용한 저축은행 소유집중도와 다각화)

  • Bae, Soo Hyun
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.2
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    • pp.77-82
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    • 2019
  • The purpose of this study is to analyze the relationship between the controlling shareholding ratio and the business diversification of savings banks The difference in this study is the analysis of the relationship between the controlling shareholding ratio of the savings bank and the business diversification using panel data. In this study, the semi-annual financial statements for the period 2014-2018 were used on the basis of a sample of 79 saving banks. The research model is analyzed using random effects generalized linear square (GLS) model considering the autocorrelation problem. As a result of the empirical analysis, it is estimated that the relationship between the controlling shareholding ratio of the savings bank and the business diversification is significant (+). This is the result of supporting the hedging hypothesis.

Regulation of glucose and glutamine metabolism to overcome cisplatin resistance in intrahepatic cholangiocarcinoma

  • So Mi Yang;Jueun Kim;Ji-Yeon Lee;Jung-Shin Lee;Ji Min Lee
    • BMB Reports
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    • v.56 no.11
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    • pp.600-605
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    • 2023
  • Intrahepatic cholangiocarcinoma (ICC) is a bile duct cancer and a rare malignant tumor with a poor prognosis owing to the lack of an early diagnosis and resistance to conventional chemotherapy. A combination of gemcitabine and cisplatin is the typically attempted first-line treatment approach. However, the underlying mechanism of resistance to chemotherapy is poorly understood. We addressed this by studying dynamics in the human ICC SCK cell line. Here, we report that the regulation of glucose and glutamine metabolism was a key factor in overcoming cisplatin resistance in SCK cells. RNA sequencing analysis revealed a high enrichment cell cycle-related gene set score in cisplatin-resistant SCK (SCK-R) cells compared to parental SCK (SCK WT) cells. Cell cycle progression correlates with increased nutrient requirement and cancer proliferation or metastasis. Commonly, cancer cells are dependent upon glucose and glutamine availability for survival and proliferation. Indeed, we observed the increased expression of GLUT (glucose transporter), ASCT2 (glutamine transporter), and cancer progression markers in SCK-R cells. Thus, we inhibited enhanced metabolic reprogramming in SCK-R cells through nutrient starvation. SCK-R cells were sensitized to cisplatin, especially under glucose starvation. Glutaminase-1 (GLS1), which is a mitochondrial enzyme involved in tumorigenesis and progression in cancer cells, was upregulated in SCK-R cells. Targeting GLS1 with the GLS1 inhibitor CB-839 (telaglenastat) effectively reduced the expression of cancer progression markers. Taken together, our study results suggest that a combination of GLUT inhibition, which mimics glucose starvation, and GLS1 inhibition could be a therapeutic strategy to increase the chemosensitivity of ICC.

Gestation length in Holstein cow depends on the number and sex of fetuses

  • Jeon, Ryoung-Hoon;Rho, Gyu-Jin
    • Korean Journal of Veterinary Research
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    • v.59 no.4
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    • pp.181-185
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    • 2019
  • The traditional calculation of gestation length (GL) in Holstein cows relies solely on the insemination day and has a high error rate for actual calving dates. The present study was conducted to develop a more accurate method of estimating GL. Among 3,578 Holstein cows, the number of fetuses had a significant (p < 0.05) effect, with GLs of 282.4 ± 2.5 days for singletons and 276.0 ± 1.6 days for twins. Within the singleton group, the GLs were 284.6 ± 1.9 days for males and 280.3 ± 1.5 days for females, a significant difference (p < 0.05). However, within the twin group, there was no difference in GLs among twin males, twin females, or twins of both sexes. Gestation was significantly shorter for singleton males born from June to August but significantly longer for twin males born in the May to June period (p < 0.05). Neither parity nor housing type was associated with any significant difference in GL. In order to predict the calving dates of Holstein cows accurately and improve their management, calculations should consider the number and sex of fetuses as well as the insemination season.

Cardiac Phenotyping of SARS-CoV-2 in British Columbia: A Prospective Echo Study With Strain Imaging

  • Jeffrey Yim;Michael Y.C. Tsang;Anand Venkataraman;Shane Balthazaar;Ken Gin;John Jue;Parvathy Nair;Christina Luong;Darwin F. Yeung;Robb Moss;Sean A Virani;Jane McKay;Margot Williams;Eric C. Sayre;Purang Abolmaesumi;Teresa S.M. Tsang
    • Journal of Cardiovascular Imaging
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    • v.31 no.3
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    • pp.125-132
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    • 2023
  • BACKGROUND: There is limited data on the residual echocardiographic findings including strain analysis among post-coronavirus disease (COVID) patients. The aim of our study is to prospectively phenotype post-COVID patients. METHODS: All patients discharged following acute COVID infection were systematically followed in the post-COVID-19 Recovery Clinic at Vancouver General Hospital and St. Paul's Hospital. At 4-18 weeks post diagnosis, patients underwent comprehensive echocardiographic assessment. Left ventricular ejection fraction (LVEF) was assessed by 3D, 2D Biplane Simpson's, or visual estimate. LV global longitudinal strain (GLS) was measured using a vendor-independent 2D speckle-tracking software (TomTec). RESULTS: A total of 127 patients (53% female, mean age 58 years) were included in our analyses. At baseline, cardiac conditions were present in 58% of the patients (15% coronary artery disease, 4% heart failure, 44% hypertension, 10% atrial fibrillation) while the remainder were free of cardiac conditions. COVID-19 serious complications were present in 79% of the patients (76% pneumonia, 37% intensive care unit admission, 21% intubation, 1% myocarditis). Normal LVEF was seen in 96% of the cohort and 97% had normal right ventricular systolic function. A high proportion (53%) had abnormal LV GLS defined as < 18%. Average LV GLS of septal and inferior segments were lower compared to that of other segments. Among patients without pre-existing cardiac conditions, LVEF was abnormal in only 1.9%, but LV GLS was abnormal in 46% of the patients. CONCLUSIONS: Most post-COVID patients had normal LVEF at 4-18 weeks post diagnosis, but over half had abnormal LV GLS.

Effect of Preparation method and Fermentation Conditions on Microbiological Characteristics of Sikhae (어류를 이용한 식해의 제조 방법에 따른 미생물의 특성변화)

  • Kim, Young-Sook;Oh, Seung-Hee;Kim, Soon-Dong
    • Food Science and Preservation
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    • v.15 no.6
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    • pp.909-914
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    • 2008
  • This study investigated microbial populations and the sensory quality of sikhae including globefish (GLS), flounder (FLS), gastropods (GAS) and whelks (WHS) during storage at 4C for 16 d following fermentation at 10C for 4 d. General bacterial numbers increased to 102 in GLS and FLS, and to 1045 in WHS and GAS after the 20 d fermentation/storage period. Lactic acid bacteria increased to 108 log cycle in GLS and FLS after 10 d ripening time, and reached this level in GAS and WHS after 15 d and 20 d, respectively. After 20 days the number of lactic acid bacteria in each of the four samples was 108. There were 104105 yeast cells/g in each of the four samples after 20 d. The number of Leuconostoc increased to over 108 log cycle after 10 d in GLS and FLS, and 15 days in GAS for WHS the increase was to 107 log cycle. The pH values of GLS, FLS, GAS and WHS 4.42, 4.56, 4.31 and pH 4.26, respectively. The Sikhae acidity for all four samples ranged from 1.551.85%. From the sensory evaluation the overall acceptability was in the order of FLS > GLS > GAS > WHS.

LOGISTICS NEW'S

  • Korea Logistics Association
    • LOGISTICS
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    • s.14
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    • pp.57-58
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    • 2006
  • 쉥커, 동북아 입지 강화위안/ 대승항운, 제42회 무역의날 국무총리 표창 수상/ CJ GLS 민병규 대표, 지난 12월 8일 취임/ 세계에서 가장 인기 있는 연말연시 선물은?

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