• Title/Summary/Keyword: GLE method

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Antioxidant and Skin Whitening Effect of Graviola (Annona muricata) Leaf Extracts (Graviola (Annona muricata) 잎 추출물의 항산화 및 미백 효과)

  • Jo, Eun Hee;Kim, In Hae;Lee, Jae Hwa
    • Applied Chemistry for Engineering
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    • v.28 no.2
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    • pp.198-205
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    • 2017
  • In this study, graviola leaf extracts (GLE) was investigated for the effect of antioxidant, antibacterial, whitening, anti-wrinkle. The antioxidant effect of GLE was measured by an electron donating ability assay. As a result, GLE increased the electron donating ability in a concentration-dependent manner. The antibacterial effect of GLE was found to show the higher antibacterial effect in Methicillin-resistant Staphylococcus aureus CCARM3115 compared with that of ampicillin by a paper disc method. The whitening effect of GLE was also measured by tyrosinase inhibition assay, and it was found that the tyrosinase activity of GLE decreased as the concentration increased. The inhibition activity of tyrosinase involved in hydroxylation reaction which is related to converting L-tyrosine to (DOPA) was higher than that of arbutin's at the concentration ranging from 125 to $250{\mu}g/mL$. In addition, GLE reduced melanin contents of B16-F10 melanoma cells in a dose-dependant manner and decreased to about 76.7% at a concentration of $100{\mu}g/mL$ Regarding wrinkling formation of GLE, an elastase inhibition assay was performed. As a result, GLE and ursolic acid were 10.5% and 56.5%, respectively under the identical concentration. These results suggest that GLE has significant antioxidant and whitening activities, and also may be potentially used as a therapeutic agent for hyperpigmentation treatment as an ingredient of whitening cosmetics.

A Fair Investigation on Safety Factor of Slope by Model Tests (모형실험에 의한 사면 안전율의 적정성 연구)

  • Kim, Yong-Sik;Park, Choon-Sik
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.1313-1323
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    • 2008
  • The purpose of this study is to understand behaviors of slopes and determine soil parameters of slopes through the triaxial compression test and the direct shear test. Following results were obtained by comparing and analyzing model tests and analysis programs of slope stability. The safety factors of the Bishop's simple method, the Morgenstern Price method, the Spencer method and the GLE method were similar to each other but safety factors of the Fellenius method and the Janbu method were different from the formers. It was found that the Bishop's simple method, the Morgenstern Price method, the Spencer method and the GLE method could be used for design but attention should be paid to the Fellenius method and the Janbu method since they underestimated safety factor.

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A Relative Study on Safe Factor by Different Analyses of Slope Stability (해석방법에 따른 사면 안전율 비교 연구)

  • An, Joon-Hee;Park, Choon-Sik;Jang, Jeong-Wook
    • Proceedings of the Korean Geotechical Society Conference
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    • 2006.03a
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    • pp.720-723
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    • 2006
  • This study performed slope stability analysis by changing analysis methods and shear strength with the slope stability analysis program. The conclusions of the study are as follows. 1) The safe factor of clayey soil applied with Bishop's simple method turned out to be similar to or slightly higher than those of other methods, for both dry and saturated conditions. 2) The safe factor of sandy soil applied with GLE method turned out to be slightly higher than those of other methods. But when applied with Bishop's simple method, it appeared to be slightly higher than those of other methods. 3) The safe factor of ordinary soil applied with GLE method showed the highest result. 4) Janbu method showed the lowest safe factor among all the methods for the above three types of soils.

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3D Generalized Langevin Equation (GLE) Approach to Gas-Surface Energy Transfer : Model H + H → $H_2/Si(100)-(2*1)$

  • Youxiang Zhang;Park, Seung Cheol
    • Bulletin of the Korean Chemical Society
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    • v.21 no.11
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    • pp.1095-1100
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    • 2000
  • we have proposed a three-dimensional GLE approach to gas-surface reactive scattering, model H + H $${\rightarrow}$H_2/Si(100)-(2$ ${\times}$1) system, and the implementation of 3D GLE method on the hydrogen on silicon surface has been presented. The formalism and algori thm of the 3D GLE are worked properly in the reactive scattering system. The calculated normal mode frequencies of surface vibrations were almost identical to previous harmonic slab calculations. The reaction probabilities were calculated for two energies. The calculations show that a very large amount of energy is transferred in surface in low energy scattering. Three different types of reaction mechanisms has been observed, which can not be shown in flat and rigid surface models. Further work on the reaction mechanisms and calculations of the vibrational and rotation distributions of products is in progress. The results will be reported elsewhere soon.

Target Length Estimation of Target by Scattering Center Number Estimation Methods (산란점 수 추정방법에 따른 표적의 길이 추정)

  • Lee, Jae-In;Yoo, Jong-Won;Kim, Nammoon;Jung, Kwangyong;Seo, Dong-Wook
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.38 no.6
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    • pp.543-551
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    • 2020
  • In this paper, we introduce a method to improve the accuracy of the length estimation of targets using a radar. The HRRP (High Resolution Range Profile) obtained from a received radar signal represents the one-dimensional scattering characteristics of a target, and peaks of the HRRP means the scattering centers that strongly scatter electromagnetic waves. By using the extracted scattering centers, the downrange length of the target, which is the length in the RLOS (Radar Line of Sight), can be estimated, and the real length of the target should be estimated considering the angle between the target and the RLOS. In order to improve the accuracy of the length estimation, parametric estimation methods, which extract scattering centers more exactly than the method using the HRRP, can be used. The parametric estimation method is applied after the number of scattering centers is determined, and is thus greatly affected by the accuracy of the number of scattering centers. In this paper, in order to improve the accuracy of target length estimation, the number of scattering centers is estimated by using AIC (Akaike Information Criteria), MDL (Minimum Descriptive Length), and GLE (Gerschgorin Likelihood Estimators), which are the source number estimation methods based on information theoretic criteria. Using the ESPRIT algorithm as a parameter estimation method, a length estimation simulation was performed for simple target CAD models, and the GLE method represented excellent performance in estimating the number of scattering centers and estimating the target length.

Design Sensitivity Analysis of Coupled MD-Continuum Systems Using Bridging Scale Approach (브리징 스케일 기법을 이용한 분자동역학-연속체 연성 시스템의 설계민감도 해석)

  • Cha, Song-Hyun;Ha, Seung-Hyun;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.27 no.3
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    • pp.137-145
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    • 2014
  • We present a design sensitivity analysis(DSA) method for multiscale problems based on bridging scale decomposition. In this paper, we utilize a bridging scale method for the coupled system analysis. Since the analysis of full MD systems requires huge amount of computational costs, a coupled system of MD-level and continuum-level simulation is usually preferred. The information exchange between the MD and continuum levels is taken place at the MD-continuum boundary. In the bridging scale method, a generalized Langevin equation(GLE) is introduced for the reduced MD system and the GLE force using a time history kernel is applied at the boundary atoms in the MD system. Therefore, we can separately analyze the MD and continuum level simulations, which can accelerate the computing process. Once the simulation of coupled problems is successful, the need for the DSA is naturally arising for the optimization of macro-scale design, where the macro scale performance of the system is maximized considering the micro scale effects. The finite difference sensitivity is impractical for the gradient based optimization of large scale problems due to the restriction of computing costs but the analytical sensitivity for the coupled system is always accurate. In this study, we derive the analytical design sensitivity to verify the accuracy and applicability to the design optimization of the coupled system.

Variations of Reaction Sequence with Precusor Mixing Methods in the Formation of $Pb(Zn_{0.6}Mg_{0.4})_{1/3}Nb_{2/3}O_3$[PZMN] ($Pb(Zn_{0.6}Mg_{0.4})_{1/3}Nb_{2/3}O_3$[PZMN] 합성시 전구체 혼합방법에 따른 반응 경로변화)

  • 김봉철;김정주;김남경;조상희
    • Journal of the Korean Ceramic Society
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    • v.35 no.5
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    • pp.458-464
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    • 1998
  • Variations of reaction sequence of $Pb(Zn_{0.6}Mg_{0.4})_{1/3}Nb_{2/3}O_3$[PZMN] with precusor mixing methods were ex-amined using X-ray diffraction and dielectric characteristics. In the present study three different types of precursor mixing methods (oxide mixing PbO+$ZnNb_2O_6+MgNb_2O_6$[Zn+MN] and PbO+(Zn,Mg)$Nb_2O_6$[ZMN] precursor mixing) were adopted. When the oxide mixing method was used for the PZMN synthesis a Zn-rich perovskite phase and pyrochlore phase were formed. Compared with PbO+ZN+MN precursor mixing method the PbO-ZMN precursor led to a lowering of the formation temperature for perovskite sin-gle phase. These variation of composition and formation temperature of the perovskite phase were dis-cussed in terms of the difference in the solid-reaction requence between these three different types of pre-cursor mixing.

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