• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.85-98
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• 2011

Objectives : The aim of this thesis is to examine the effect of acupuncture treatment at the GB37 on normal humans by using the power spectral analysis of the EEG. Methods : EEG (Electroencephalogram) power spectrum exhibits site-specific and state-related differences in specific frequency bands. In this thesis, the power spectrum was measured by the complexity. the 32 channels EEG study was carried out in the 13 subjects (12 males ; age=22.58 years old, 1 females ; 22 years old). Results : In the ${\alpha}$ (alpha) band, the power values at F7, F3, F4, F8, FTC2, C4, T4, CP1, CP2, TCP2, TT2, Pz, P4, Po1, Po2, O1, Oz, O2 channels (p<0.05) during the GB37-acupoint treatment were significantly changed. And in many channels were decreased. In the ${\beta}$ (beta) band, the power values at Cz, C4, T4, Tcp1, T6, Po1, O1, Oz, O2 channels (p<0.05) during the GB37-acupoint treatment were significantly changed. And in many channels were decreased. In the ${\delta}$(delta) band, the power values at Fp1, TT2 channels (p<0.05) during the GB37-acupoint treatment were significantly changed. And in many channels were decreased. In the $\theta$ (theta) band, the power values at Fp1, F8, FTC2, Pz channels (p<0.05) during the GB37-acupoint treatment were significantly changed. And in many channels were decreased. Conclusions : This results suggest that the acupuncture treatment at the GB37 significantly mostly change the power spectrum value on the alpha (18 channels), beta (9 channels) bands.

• Korean Journal of Acupuncture
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• v.30 no.1
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• pp.47-55
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• 2013

Objectives : The purpose of this study was to determine whether electroacupuncture(EA) is effective in reducing pain on the severe ankle sprain classified as grade 3 in rats. Methods : The severe(grade 3) ankle sprain model was induced surgically by ankle ligament injury(the anterior talofibular, the calcaneofibular and the posterior talofibular) in the Sprague-Dawley rats(180~250 g). The effects of EA on weight bearing forces(WBR) of the affected foot were examined in a rat model of ankle sprain. EA was applied to either SI6, ST37, GB34, GB39 or GB42 acupoints by trains of electrical pulses(2 Hz, 1 ms pulse width, 2 mA intensity) for 15 min. Results : Cutting of the lateral ankle ligament complex produced the severe ankle sprain symptoms as grade 3. EA of the contralateral SI6 resulted in more analgesic effect than one of ipsilateral SI6 even though there was significant effect. EA of the ipsilateral GB34 and GB39 produced potent analgesic effects on the surgical ankle sprained pain behaviors. However, there were no significant analgesic effects in the contralateral GB34 and GB39 EA groups. In addition, both side of ST37 and GB42 did not result in analgesic effect on the surgical ankle sprained rat. Conclusions : The data suggest that EA induced analgesia shows point specificity on the severe ankle sprained pain model classified as grade 3.

• KSBB Journal
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• v.22 no.2
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• pp.109-113
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• 2007

Suspension culture of recombinant Chinese hamster ovary (CHO) cells producing follicle-stimulating hormone was performed to investigate the effect of glycine betaine on cell growth and FSH production at low culture temperature. At 28$^{\circ}C$, cell growth was suppressed, but cell viability remained high for a longer culture period. When the culture temperature was lowered from 37$^{\circ}C$ to 28$^{\circ}C$, more than 14-fold increase in the maximum FSH titer was achieved. In batch culture at 28$^{\circ}C$, the use of 15 mM glycine betaine (GB) to culture medium resulted in the enhancement of maximum cell density and FSH titer by 11% and 17%, respectively, compared to the culture without GB. In pseudo-perfusion culture at 28$^{\circ}C$ with the exchange of fresh medium containing 15 mM GB, a final FSH of $2,058{\mu}g$ which is approximately 1.4-fold higher as compared to the culture without GB was obtained. This enhanced FSH production with 15 mM GB was not just because of enhanced specific FSH productivity (qFSH), but mainly because of the extended culture longevity. Taken together, this result demonstrates that the application of GB at low culture temperature is feasible to enhance the production of recombinant proteins in rCHO cells.

• 전기의세계
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• v.42 no.6
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• pp.32-37
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• 1993

광통신 기술은 지난 25년간 비약적인 발전을하여 이미 세계적으로 2.4Gb/S시스템의 실용화, 해저 광케이블 포설 등이 이루어졌으며 고속 광변조 기술, 광폭증 기술, 광 FDM기술 등 핵심기술의 개발에 따라 10Gb/s이상의 초고속 광통신 시스템의 실용화가 가시화 되고 있으며, 또한 차세대 정보통신 서비스인 B-ISDN서비스에의 응용을 가능하게 하고 있다.

• Journal of Mushroom
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• v.19 no.4
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• pp.341-346
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• 2021

Simple sequence repeats (SSRs) were isolated from major Pleurotus pulmonarius cultivars in Korea, namely 'HS47' (monokaryon, gamete of 'Santari'), 'GB19' (monokaryon, gamete of 'Santari'), 'Hosan,' 'Yeoleumneutali1,' 'Sambok,' 'Gangsan,' 'Yaksan,' 'Jasan,' 'Hyangsan,' and 'Yeoleumneutali2,' and characterized via HiSeq genome sequencing and bioinformatic analysis. The genome sizes of the monokaryons 'HS47' and 'GB19' were estimated to be 37.3 and 37.2 Mb, respectively, and those of the other dikaryotic cultivars ranged from 47.1 to 61.1 Mb. A total of 711 (smallest) and 1,106 (1.5 times the smallest) SSRs were found in the 'HS47' and 'Gangsan' genomes, respectively. Hexanucleotide and octanucleotide motifs accounted for the top two fractions of all SSRs. CGA/TCG, A/T, and CTC/GAG were the most frequently detected nucleotides in the SSRs. Most of the SSRs were 21~30 nucleotides long (hypervariable for application), accounting for 70% of all lengths of SSRs.

• ETRI Journal
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• v.37 no.6
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• pp.1120-1128
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• 2015

We propose a pseudo optical N-level pulse-amplitude modulation (PO PAM-N) signal using a few externally-modulated lasers (EMLs) operating at different wavelengths, which is suitable for upgrading the transmission speed over an optical link of < 10 km single-mode fiber with low-cost components. To compare a PO PAM-N signal with that of a standard optical PAM-N signal, we perform experiments for evaluating the performance of a 51.56-Gb/s PO PAM-4 signal and standard 51.56-Gb/s optical PAM-4 signal. The receiver sensitivity (at $BER=10^{-5}$) of the PO PAM-4 signal is 1.5 dB better than the receiver sensitivity of a standard optical PAM-4 signal. We also investigate the feasibility of PO PAM-N (N = 4, 8, and 16) signals operating at 103.12 Gb/s, considering relative intensity noise, timing jitter, extinction ratio (ER) of EMLs, and dispersion. From the results, a PO PAM-8 signal performs better than PO PAM-4 and PO PAM-16 signals at 103.12 Gb/s. Finally, we suggest a timing control method to suppress the effect of dispersion in a PO PAM-N signal. We show that the tolerance to dispersion of a 103.12-Gb/s PO PAM-8 signal can be improved to ${\pm}40ps/nm$ by applying a proposed scheme.

• Applied Microscopy
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• v.37 no.4
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• pp.239-248
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• 2007

Alteration of temperature is one of cancer therapies. In general, severe hyperthermia(around $43^{\circ}C$) and hypothermia(around $18^{\circ}C$) trigger apoptosis through mitochondria, though the specific mechanism is still unknown. CC-t6 and GB-d1 cell lines, which were originally derived from human cholangiocarcinoma and gall bladder cancer, were established from a metastatic lymph node. To investigate the mechanism of metastatic cancer cell response to thermal stresses, hyperthermia($37^{\circ}C{\rightarrow}43^{\circ}C$) and hypothermia($37^{\circ}C{\rightarrow}17.4^{\circ}C$) were designed. Thermal stresses did not induce apoptosis but necrotic cell death. Any alterations of caspase-3, -9, cytochrome c, Bax, and Bcl-2 were not found in both hyperthermia and hypothermia exposed fells using western blot analysis. In the transmission electron microscopy, typical necrotic, but not apoptotic, changes were observed. These results suggest that temperature changes induce cell death through necrotic pathway in metastatic cancer in vitro, and it can be one of effective anticancer methods.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37B no.9
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• pp.814-821
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• 2012

We propose a network processor called an OmniFlow processor capable of wire-speed flow management by a hardware-based flow admission control(FAC) in this paper. Because the OmniFlow processor can set up and release a wire-speed connection for flows, the update period of flows can be set to a short time, and only active flows can be effectively managed by terminating a flow that does not have a packet transmitted within this period. Therefore, the FAC can be used to provide a reliable transmission of UDP as well as TCP applications. This processor is fabricated in 65nm CMOS technology, and total gate count is 25 million. It has 40 Gb/s throughput performance in using the 32 RISC cores when maximum operating frequency is 555MHz.

• Korean Journal of Organic Agriculture
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• v.10 no.4
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• pp.37-45
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• 2002

This study was conduction to investigate the effects of natural materials such as $GB_{10}$ chitofarm, chaff charcoal, and chaff charcoal sap, on quality and yield of chinese cabbage, Natural materials were treated on seeds soil, and leaves. The total plant weight, head weight, head length, head width, leaf length, leaf width, and sugar content of chinese cabbage in treatment with natural materials showed significant difference compared with control. The yield of chinese cabbage in $GB_{10}$ soil treatment and 1% $GB_{10}$ leaf treatment was increased 53% compared with control. The total nitrogen $P_2O_5$, $K_2O$, CaO, MgO, $Na_2O$, and Mn in total plant were analyzed. The chemical components were increased in total plant of chinese cabbage treated with natural materials compared with control natural materials increased the quality of chinese cabbage.

• Journal of radiological science and technology
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• v.29 no.4
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• pp.267-274
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• 2006

The evaluation of GB stones with ultrasound has proved to be useful procedure in patient with symptoms of cholelithiasis. GB is evaluated for size, wall thickness, presence of internal reflections within the lumen and posterior acoustic shadowing or enhancement in Ultrsonography. The patient position should be shifted during procedure to demonstrate further the presence of stone within the GB. Patient scanned at the Rt. subcostal region in supine, right lateral, Lt. down decubitus, and upright sitting position. So GB stone should shift to dependent area of GB. Often, GB is not markedly distended in the presence of cholethiasis, and so the diagnosis becomes more difficult. One of the more difficult areas for detection of a GB stones are embeded in the cystic duct region. And since the GB is adjacent to the duodenum and hepatic flexure, its may be difficult to visualizing a GB stone. When patient study position changes frome supine to other position, stones displaced the site. But if its are polyps, not changes the site whatever patient positions. It is very important to what make different GB stones or polyps. We have studied about mobility of GB stones according to the patients position(supine, Lt. down decubitus, $30^{\circ} LAO. sitting and hand-knee). So we have a result, stones wherever localized within the GB, changed 100% its position in the hand-knee position and the others appeared at least 90%. In this study, when a large stones are located through fundus-body and body-neck, does not changing the stones position in spite of varied patient's positions. But hand-knee positions can identified GB stones, because its make changed the position of stons from posterior wall to anterior wall within the GB. We recommend the hand-knee position for differentiation GB stones from polyps.