• 한국가스학회지
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• 제17권2호
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• pp.9-20
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• 2013

고갈가스전은 저류층을 개발할 당시 충분한 탄성파 탐사 및 시추 등을 수행하기 때문에 지질구조와 저류층의 물성 등의 파악이 완료된 상태이므로 가스저장전으로의 전환이 용이하다. 이러한 고갈가스전을 가스저장전으로 전환 시 저류층의 압력을 유지하기 위한 쿠션가스는 재생산을 위해 주입된 워킹가스의 재생산율에 영향을 미친다. 본 연구에서는 쿠션가스와 가스재생산율과의 관계 및 재생산 사이클에 따른 적정 쿠션가스의 양을 분석하기 위해 가스저장전의 주입 및 재생산에 대한 시뮬레이션을 수행하였다. 주입 및 재생산 사이클은 5개월 주입 5개월 생산, 7개월 주입 3개월 생산 두 가지 경우에 대한 분석을 수행하였다. 본 시스템을 대상으로 수행한 분석결과, 5개월 주입 5개월 생산 사이클의 경우 최소 10개의 생산정으로 50%의 쿠션가스를 유지해야 안정적인 생산이 가능하였고, 7개월 주입 3개월 생산 사이클의 경우 12개의 생산정으로 60%의 쿠션가스를 유지해야 안정적인 재생산이 가능한 것으로 산출되었다.

• Molecules and Cells
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• 제42권5호
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• pp.397-405
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• 2019

The regulatory role of long noncoding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5) in both cancerous and noncancerous cells have been widely reported. This study aimed to evaluate the role of lncRNA GAS5 in heart failure caused by myocardial infarction. We reported that silence of lncRNA GAS5 attenuated hypoxia-triggered cell death, as cell viability was increased and apoptosis rate was decreased. This phenomenon was coupled with the down-regulated expression of p53, Bax and cleaved caspase-3, as well as the up-regulated expression of CyclinD1, CDK4 and Bcl-2. At the meantime, the expression of four heart failure-related miR-NAs was altered when lncRNA GAS5 was silenced (miR-21 and miR-142-5p were up-regulated; miR-30b and miR-93 were down-regulated). RNA immunoprecipitation assay results showed that lncRNA GAS5 worked as a molecular sponge for miR-142-5p. More interestingly, the protective actions of lncRNA GAS5 silence on hypoxia-stimulated cells were attenuated by miR-142-5p suppression. Besides, TP53INP1 was a target gene for miR-142-5p. Silence of lncRNA GAS5 promoted the activation of PI3K/AKT and MEK/ERK signaling pathways in a miR-142-5p-dependent manner. Collectively, this study demonstrated that silence of lncRNA GAS5 protected H9c2 cells against hypoxia-induced injury possibly via sponging miR-142-5p, functionally releasing TP53INP1 mRNA transcripts that are normally targeted by miR-142-5p.

• 한국가스학회지
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• 제23권5호
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• pp.15-23
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• 2019

최근 5년간 국내 가스 사고 중 약 42.5%가 인적요소에 의해 발생하였고, 38%가 주택에서 발생, 또한 2017년 대비 제품 노후 / 고장으로 발생한 사고가 1년 사이에 2배 이상 급증하여 가정 내 가스시설 노후화에 대한 대비책이 필요하나 현재는 모니터링 수준에서 그치고 있어 가정 내 가스시설에 대한 예측 및 예방이 불가능한 상황이다. 본 연구에서는 LPWA 양방향 통신 방식을 통해 모니터링 및 원격 제어 기능을 구현하여 99.32%의 데이터 송수신 정확도를 확보한 IoT 기반 가정 가스시설 안전 플랫폼 서비스를 구축 및 개발하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.1077-1082
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• 2013

Background: Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. We aimed to explore whether the expression of Long Non-Coding RNA (LncRNA) growth arrest-specific transcript 5 (GAS5) is associated with RCC genesis. Methods: We selected twelve clinical samples diagnosed for renal clear cell carcinoma and found that the LncRNA GAS5 transcript levels were significantly reduced relative to those in adjacent unaffected normal renal tissues. Results: In addition, expression of GAS5 was lower in the RCC cell line A498 than that in normal renal cell line HK-2. Furthermore, using functional expression cloning, we found that overexpression of GAS5 in A498 cells inhibited cell proliferation, induced cell apoptosis and arrested cell cycling. At the same time, the migration and invasion potential of A498 cells were inhibited compared to control groups. Conclusion: Our study provided the first evidence that a decrease in GAS5 expression is associated with RCC genesis and progression and overexpression of GAS5 can act as a tumor suppressor for RCC, providing a potential attractive therapeutic approach for this malignancy.

• 한국기계가공학회지
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• 제18권5호
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• pp.1-8
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• 2019

Breath analysis using a portable device is better than the classical breath analysis system in terms of installation and operation. There is an increasing need to develop cost-effective equipment for testing gas sensors from the viewpoint of functionalities that can be applied applicable to portable devices. In the present study, an economical gas chamber for in-situ gas measurement is implemented with a single gas chamber without using expensive gas storage and control equipment; the gas response characteristics are analyzed using the above-described chamber. The main features of the implemented gas chamber are simple injection procedure, improved gas diffusion, easy measurement and cleaning, support for low-power mode measurement function for portable devices, and open source platform. Moreover, an analysis of gas response characteristics based on changes in sensor voltage show that the sensitivity and 90% response time are affected by the sensor voltage. Furthermore, the sensitivity graph has an inflection point in a specific range. The gas sensor applied in this study showed fast response speed and high sensitivity for sensor voltages of 3.0-3.5 V, regardless of the concentration of acetone gas, the target gas used in this study.

• 한국가스학회:학술대회논문집
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• 한국가스학회 1997년도 추계학술발표회 논문집
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• pp.33-38
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• 1997

Demand of the clean and convenient natural gas has continuously increased with recognizing of the environment problem since liquefied natural gas was introduced in Korea. Clean fuel natural gas was supplied to each city through high tensile strength pipeline connected by welding. Grades of pipeline were divided into the high and middle pressure according to supply pressure. Pipeline was welded mainly SMA welding process due to its easy handling, the other welding process was adopted according to the constructing condition. We were examined on the microstructure variation and mechanical properties of weld metal for high pressure pipeline, API 5L X-42.

• 공학논문집
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• 제6권2호
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• pp.85-98
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• 2004

The adsorption equilibrium data for the binary gas mixture system from the pure gas adsorption data of carbon dioxide and ethylene on ZSM-5 prepared were predicted. The binary gas mixture adsorption data have been examined against predicted values by two models-the vacancy solution model(VSM) and the statistical thermodynamic model(STM), using parameters obtained from the single component isotherm. The binary gas mixture data for the carbon dioxide-ethylene system were obtained for cation exchanged forms of ZSM-5 for the gas phase carbon dioxide mole fraction of 0.752 at $37^{\circ}C$ and 1 atm. The experimental adsorption phase diagrams were obtained for carbon dioxide-ethylene on sodium form ZSM-5 synthesized. The single component adsorption isotherms for carbon dioxide and ethylene were also obtained for this zeolite. The single component data were used to obtain parameters derived in two models. These parameters were, in turn, used to predict the binary mixture isotherms for this zeolite. Both the vacancy solution and the statistical thermodynamic models give satisfactory predictions of adsorption phase diagrams for the binary gas mixtures of carbon dioxide and ethylene on sodium exchanged ZSM-5. Also the correlation between the experimental data and the predicted values is generally in good agreement. The system appears to show ideal behavior with a relatively constant separation factor. The slight increase in adsorption capacity with an increase in ionic radius is due, in part, to the higher polarizability associated with larger cations.

• 에너지공학
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• 제6권1호
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• pp.26-33
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• 1997

유기주형물질을 첨가하지 않고 순수하고 결정성이 좋은 구리이온이 교환된 Cu-ZSM5 제올라이트 촉매를 제조하여 NO 분해반응 실험에 사용하였다. 구리이온교환 정도의 증가에 따라 NO 분해 활성은 점차로 증가하였고 100% 이상으로 구리이온교환 시에도 지속적으로 증가하였다. 산소의 존재하에서 NO의 분해 활성은 $O_2$양이 증가할수록 저하되었고, NO, $O_2$TPD실험 결과 NO의 분해 활성점과 $O_2$의 흡착점은 같은 것으로 판명되었다. 또한 50$0^{\circ}C$에서 전처리 후에도 촉매 표면의 $O_2$는 완전히 탈착되지 않았으며, 50$0^{\circ}C$에서 수소 처리를 하였을 경우 반응 활성이 초기에 상당량 향상되는 현상으로 보아 촉매 표면에 흡착된 산소가 NO의 분해반응 활성을 저하시키는 요인이 된다는 것을 알 수 있었다.

• 분석과학
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• 제34권5호
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• pp.202-211
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• 2021

Volatile organic compounds (VOCs) in hazardous air pollutants (HAPs) have been regulated by the Air Pollution Control Act (1978) and their atmospheric concentrations have been monitored in 39 monitor sites in Korea. However, measurement standards of volatile organic compounds (VOCs) in HAPs at ambient levels have not been established in Korea. Primary reference gas mixtures (measurement standards) at ambient levels are required for accurately monitoring atmospheric VOCs in HAPs and managing their emissions. In this study, primary reference gas mixtures (PRMs) at 5 nmol/mol were developed in order to establish primary national standards of VOCs in HAPs at ambient levels. Primary reference gas mixtures (PRMs) were prepared in pressurized aluminum cylinders with special internal surface treatment using gravimetric method. Analytical methods using gas chromatography-flame ionization detector (GC-FID) coupled with a cryogenic preconcentrator were also developed to verify the consistency of gravimetrically prepared HAP VOCs PRMs. Three different columns installed in the GC-FID were evaluated and compared for the retention times and separation of eighteen target components in a chromatogram. Results show that the HAP VOCs PRMs at 5 nmol/mol were consistent within a relative expanded uncertainty (k=2) of less than 3 % except acrylonitrile (less than 6 %) and the 18 VOCs were stable for 1 year within their associated uncertainties.

• 한국가스학회지
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• 제17권5호
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• pp.51-57
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• 2013

최근 들어 다양한 재료 및 제조기술의 개발로 가스관 품질이 향상되어 매설심도를 저심도화 할 수 있는 환경이 조성되고 있다. 또한 선진 외국과 비교하여 국내 매설깊이 기준이 약 50cm 정도 깊은 것으로 조사되어 시공비용, 차량지체비용 등을 고려하였을 때 비효율적인 매설깊이 규정인 것으로 판단된다. 따라서 본 연구에서는 매설깊이 변화(0.8m, 1.0m, 1.2m)에 따른 가스관의 응력 및 변형 거동을 분석하였다. 본 연구에서는 수치해석 및 현장시험을 통하여 매설심도 변화에 따른 가스관(API 5L)의 거동특성을 분석하였다. 분석결과, 매설심도의 감소가 가스관의 응력, 변형 특성에 큰 영향을 미치지 않을 것으로 판단되었다.