• 제목/요약/키워드: GAP-43

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A Prior Study on the Effect of Yukmijihwang-tang to Regeneration of Injured Peripheral Nerve Fiber (육미지황탕(六味地黃湯)이 손상된 말초신경섬유 재생에 미치는 효과에 대한 사전 연구)

  • Han, Gyu-Seol;Yu, Byeong-Chan;An, Jung-Jo;Jo, Hyun-Kyung;Ryu, Ho-Ryong;Seol, In-Chan;Kim, Yoon-Sik
    • Journal of Haehwa Medicine
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    • v.15 no.2
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    • pp.181-186
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    • 2006
  • Peripheral axons in vertebrate animals can regenerate after nerve injury and accomplish its functional recovery. Numerous studies have revealed that diverse molecular factors are induced during axonal regeneration and their potential roles in axonal regeneration have been studied. Examples is N-CAM, L1, P0, nerve growth factors, GAP-43 and so forth. However, most of the studies on axonal regeneration have been primarily focused on axon fiber regrowth and elucidating molecular factors, and relatively less is known about functional recovery. Also, specific drugs or drug components used in the oriental medicine in relation to nerve fiber regeneration have not been known. And thus, in the present, a study on the effect of Yukmijihwang-tang components and Yukmijihwang-tang extracts to regeneration of peripheral axon fiber is underway by immunofluorescence staining. Therefore, this prior application of Yukmijihwang-tang with documents consideration is reported with a plea for further investigation.

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Fetal Growth Rate and Determination of Weaning Time for Adoption of Kittens in Free-Roaming Cats

  • Kang, Yeon-Jeong;Kim, Ill-Hwa;Kang, Hyun-Gu
    • Journal of Veterinary Clinics
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    • v.34 no.1
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    • pp.34-38
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    • 2017
  • The aims of the present study were to determine the weaning time for adoption of kittens, and to evaluate the fetal growth rate during pregnant in free-roaming cats. This study was conducted on three pregnant free-roaming cats (one feral cat and two stray cats). Radiography and ultrasonography were performed on the feral cat and on one of the stray cats. In the feral cat, fetal head diameter was measured once during pregnancy to determine the cesarean section (C-sec) time. In the stray cat, serial fetal head diameter was measured from capture to parturition. The body weight of the feral cat's kittens was measured from 4 weeks postpartum because of their wildness. That of the stray cats' kittens was measured immediately after birth. In the feral cat, scheduled C-sec was performed at predicted parturition day by measurement of head diameter, and six healthy kittens were delivered. The stray cats had five and six kittens by natural delivery, respectively. In the body weight gain of feral and stray cat's kittens, two female kittens of the feral cat lost weight rapidly after they were separated from their mother, so they were returned to their mother for 1 more week. After that, the female kittens grew up without difficulty. Body weight gain of the ten kittens born to the two stray cats consistently increased, by approximately 14 g every day, until they were adopted. The body weight of kittens born by natural delivery was on average 77.5 g greater than that of kittens born by C-sec. However, the gap decreased with time. During the stray cat's pregnancy, fetal head diameter increased by 0.042 cm every day. Maximum head size before parturition was 2.43 cm. These results indicate that the weaning time for adoption of kittens was 5-week-old postpartum.

Developmental and Phylogenetic Characteristics of Stellantchasmus falcatus (Trematoda: Heterophyidae) from Thailand

  • Sripalwit, Pralongyut;Wongsawad, Chalobol;Chontananarth, Thapana;Anuntalabhochai, Somboon;Wongsawad, Pheravut;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.53 no.2
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    • pp.201-207
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    • 2015
  • This study aimed to investigate the infection status, worm development, and phylogenetic characteristics of the intestinal trematode, Stellantchasmus falcatus. The metacercariae of S. falcatus were detected only in the half-beak (Dermogenus pusillus) out of the 4 fish species examined. Their prevalence was 90.0%, and the intensity of infection was 919 metacercariae on average. Worms were recovered from 33 (97.1%) of 34 chicks that were experimentally infected with 200 S. falcatus metacercariae each, and the average recovery rate was 43.0%. The body size and inner organs of S. falcatus quickly increased in the experimental chicks over days 1-2 post-infection (PI). In addition, ITS2 sequence data of this parasite were analyzed to examine the phylogenetic relationships with other trematodes using the UPGMA method. The results indicated that the ITS2 sequence data recorded from trematodes in the family Heterophyidae appeared to be monophyletic. This study concluded that D. pusillus serves as a compatible second intermediate host of S. falcatus in Thailand and that S. falcatus can develop rapidly in the experimental chicks. Data collected from this study can help to close the gap in knowledge regarding the epidemiology, biology, and phylogenetic characteristics of S. falcatus in Thailand.

Differences in Obesity Rates Between People With and Without Disabilities and the Association of Disability and Obesity: A Nationwide Population Study in South Korea

  • Oh, Moo-Kyung;Jang, Hyeon-Gap;Kim, Yong-Ik;Jo, Belong;Kim, Yoon;Park, Jong-Heon;Lee, Jin-Seok
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.4
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    • pp.211-218
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    • 2012
  • Objectives: The objective of this study was to identify the differences in obesity rates among people with and without disabilities, and evaluate the relationship between obesity rates and the existence of disabilities or characteristics of disabilities. Methods: Mass screening data from 2008 from the National Disability Registry and National Health Insurance (NHI) are used. For analysis, we classified physical disability into three subtypes: upper limb disability, lower limb disability, and spinal cord injury. For a control group, we extracted people without disabilities by each subtype. To adjust for the participation rate in the NHI mass screening, we calculated and adopted the weight stratified by sex, age, and grade of disability. Differences in obesity rates between people with and without disabilities were examined by a chi-squared test. In addition, the effect of the existence of disabilities and grade of disabilities on obesity was examined by multiple logistic regression analysis. Results: People with disabilities were found to have a higher obesity rate than those without disabilities. The obesity rates were 35.2% and 35.0% (people with disabilities vs. without disabilities) in the upper limb disability, 44.5% and 34.8% in the lower limb disability, 43.4% and 34.6% in the spinal cord injury. The odds for existence of physical disability and grade of disability are higher than the nondisabilities. Conclusions: These results show that people with physical disability have a higher vulnerability to obesity.

Analysis of the Impacts of Korea-US FTA on the Pork Market in Korea (한.미 FTA가 국내산 돼지고기 시장에 미치는 영향 분석)

  • Ahn, Byeong-Il;Jo, Young-Deuk
    • Journal of agriculture & life science
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    • v.43 no.2
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    • pp.55-63
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    • 2009
  • This paper analyzes the effects of Korea-US FTA on the pork market in Korea. Without distinction of chilled and frozen pork, previous studies that investigate the impacts of FTA posit single category of pork. Moreover, many prior studies assume the domestic pork and imported one are homogenous. This study fills this gap. The simulated influences of Korea-US FTA on the price of domesitc pork are -2.69 to -15.96 percents. The FTA is simulated to result in the fall of domestic production by 1.35 to 5.6 percents.

Analysis of price variance of raw herbal medicines in Korea (한약재의 연도·산지·업체별 가격변동 분석 연구)

  • Kim, Dongsu;Lim, Byungmook;Hyun, Eunhye;Lee, Eunkyung
    • Journal of Society of Preventive Korean Medicine
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    • v.23 no.2
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    • pp.43-51
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    • 2019
  • Objectives : This study aimed to analyze price variance by year, region and company of raw herbal medicines to draw payment system for herbal medicine insurances in the National Health Insurance. Methods : To analyse price variance, we used 2015-2017 data of 'Quality test results of imported herbal medicines' provided by Korea Pharmaceutical Traders Association and 'Price data of 56 raw herbal medicines' that was surveyed by the Association of Korean Medicine. We analysed gap of highest price and lowest price those were compared with average price and coefficient of variation(CV) of prices by year, region and company of raw herbal medicines. Results : In analysing 3 years data, the highest price was 23.2% higher, and the lowest price was 19.1% lower than the average price. As of 2018, the average price of domestic produced herbal medicines was 1,8 times higher than that of imported herbal medicines. By companies, the highest price was 117.5% higher, and the lowest price was 57.3% lower than the average price. Conclusions : The price of herbal medicines varied by production year, region and company. This results suggest that comprehensive payment model needs to be considered in modeling the health insurance coverage for herbal medicine decoctions.

Analysis on the Actual Status of Users of Public Nature Burial and Cremated Bodies Using the Public Cremation Facilities in the Capital Area through the Funeral Information System and the Activation Plan of the Public Nature Burial

  • Choi, Jae-sil;Kim, Jeong-lae
    • International journal of advanced smart convergence
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    • v.8 no.3
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    • pp.123-130
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    • 2019
  • In the study, we suggest that the activation plan of the public nature burial in the capital area through funeral information system as follows. First, according to the report on the social survey announced by the National Statistical Office in December 2017, the Korean people's preference of nature burial was 43.6% while the actual utilization rate of national nature burial in 2017 was only 8.8%, which showed a huge gap between preference and utilization rate of nature burial. Therefore, through the activities to improve the awareness of nature burial by performing the national promotion and education, and also the investment for the expansion or improvement of nature burial facilities in the level of central government and local government, the preference of nature burial should be led to the actual demand. Second, during the period from 2011 to 2018, the utilization rate of public nature burial in the capital area was annually increased by average 26.9%, which showed the huge increase of demand for nature burial. Thus, each local government should carry forward the policies for expanding the supply of public nature burial focusing on the woodland burial showing the high preference of users of public nature burial. Third, even though the public cremation facilities are installed or operated by local governments in the capital area, Seongnam City without the public cremation facilities should install the public nature burial for the enhancement of users convenience by providing the One Stop Total Funeral Service.

Preventive Measures Against COVID-19 in Small- and Mid-sized Enterprises from an Early Stage of the Epidemic in Daegu and Gyeongsangbuk-do

  • Baek, Kiook;Kim, Seong-Hui;Park, Chulyong;Sakong, Joon
    • Safety and Health at Work
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    • v.13 no.3
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    • pp.294-301
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    • 2022
  • Background: In the early stage of the coronavirus disease 2019 (COVID-19) epidemic, small- and midsized enterprises (SMEs) may be an important transmission consideration. The study aimed to identify the pattern of COVID-19 prevention measures during the outbreaks in Daegu and Gyeongsangbuk-do at the early stage of COVID-19. Moreover, we investigated whether SME size and past experiences affected the preventive measures implemented in the region. Methods: A survey detailing the general characteristics and implementation of 12 preventive activities was conducted in 122 SMEs in Daegu and Gyeongsangbuk-do. The survey was analyzed by size and operation period. Results: The study subjects consisted of 53 (43.4%) workplaces with 1-5 employees, 50 (40.9%) workplaces with 6-30 employees, and 19 (15.6%) workplaces with 31-49 employees. The lowest three items among those surveyed were 'symptomatic workers to stay home for 3-4 days' (17.2%), 'work remotely' (18.9%), and 'video meetings' (20.5%). There were significant differences in the rate of several preventive measures implemented. The larger sized SMEs, the higher the number of implementations (p < 0.01). The operation period had no significant relationship with the implementation of preventive measures. The same pattern was observed in multiple generalized linear regression with covariate adjustment. Conclusion: Preventive measures among SMEs with fewer than 50 employees were identified. Even within SMEs, a gap in preventive measures according to size was confirmed. To prevent the spread of infection and protect workers' right to health, different support for different sized SMEs is necessary.

Characteristics of VOx Thin Film, NiOx Thin Film, and CuIx Thin Film for Carrier Selective Contacts Solar Cells (전하선택접촉 태양전지 적용을 위한 VOx 박막, NiOx 박막, CuIx 박막의 특성 연구)

  • Kiseok Jeon;Minseob Kim;Eunbi Lee;Jinho Shin;Sangwoo Lim;Chaehwan Jeong
    • Current Photovoltaic Research
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    • v.11 no.2
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    • pp.39-43
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    • 2023
  • Carrier-selective contacts (CSCs) solar cells are considerably attractive on highly efficient crystalline silicon heterojunction (SHJ) solar cells due to their advantages of high thermal tolerance and the simple fabrication process. CSCs solar cells require a hole selective contact (HSC) layer that selectively collects only holes. In order to selectively collect holes, it must have a work function characteristic of 5.0 eV or more when contacted with n-type Si. The VOx, NiOx, and CuIx thin films were fabricated and analyzed respectively to confirm their potential usage as a hole-selective contact (HSC) layer. All thin films showed characteristics of band-gap engergy > 3.0 eV, work function > 5.0 eV and minority carrier lifetime > 1.5 ms.

Effects of Pre- and Post-workout Energy Bar Supplementation on Blood Lactate and Fitness in Young Adults with CrossFit Training: A randomized crossover study

  • Byung-Gul Lim;Xinxing Li;Wook Song
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.4
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    • pp.61-71
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    • 2023
  • Purpose : Energy bars are increasingly popular among active individuals, yet their timing and nutrient combinations' impact on exercise adaptation remains unclear. This study aims to address this knowledge gap by investigating whether the combination of pre- and post-workout supplementation can synergistically enhance fitness and alleviate fatigue in trained CrossFit participants. Investigate if combining pre- and post-workout supplements can enhance fitness and blood lactate management in trained CrossFit participants, potentially improving exercise performance for this group. Methods : In a randomized crossover study, 20 trained CrossFit individuals (11 males, 9 females) completed thrice-weekly 60-minute CrossFit sessions for 3 weeks, with a one-week washout period. Participants were randomly assigned to either a chocolate bar group (CH, 45 g, 225 kcal) or an energy bar group (ES, 48 g, 238 kcal, with protein, caffeine, taurine, and BCAAs). For one week, participants consumed two bars of their assigned supplement five minutes before and after workouts. After a washout period, they switched supplements. Blood lactate levels and a visual analog scale (VAS) were assessed before, immediately after, and 30 minutes post-workout. Fitness tests (hand grip, broad jump, sit-ups) were conducted at baseline and 30 minutes post-final workout. Data were analyzed using two-way repeated measures ANOVA (p<.05), 95 % confidence intervals, and magnitude inferences. Results : Hand grip strength (t=-5.60, p=.000), broad jump (t=-3.43, p=.003) and sit up (t=-3.94, p=.001) were significantly increased in the ES group. Compared to CH group, there was a significant time and group interactions for blood lactate level (F=5.51, p=.008) and VAS(F=31.67, p=.000) in the ES group. Conclusion : Pre- and post-workout energy bar supplementation may have a beneficial effect on blood lactate clearance and fitness in trained CrossFit individual. The combination of proprietary supplements taken may provide benefits for removing the blood lactate during high-intensity functional exercise.