• 제목/요약/키워드: GAM-1

검색결과 342건 처리시간 0.029초

새성기형 50예의 임상적 고찰 (A Clinical Study of Branchial Apparatus Anomalies)

  • 감봉수;주종수;김상효;백낙환
    • 대한두경부종양학회지
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    • 제8권1호
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    • pp.6-13
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    • 1992
  • Branchial apparatus anomaly is rarely encountered congenital neck disease, it presents a palpable non-tender mass or fistulous opening existed at any site from external auditory canal or mandible angle to lower part of neck We have reviewed the records of 50 patients operated upon for branchial cleft anomaly, at Department of Surgery, Inje University Hospital, between 1981 and 1990, and the following results were obtained. I) In the classificiation of branchial cleft anomaly, first branchial fistula was 1 case, second branchial cyst 32 cases, second branchial sinus 11 cases, second branchial fistula 5 cases and third branchial fistula 1 case. 2) There were 20 men and 30 women in this series and male to female ratio was 2:3. 3) The age at first clinical presentation was 1st decade 15 cases, 2nd decade 10 cases, 3rd decade 17 cases, 4th decade 5 cases and 5th decade 3 cases. The peak age incidence was 3rd decade in overall, but the cyst was most common in 2nd decade, and majority of sinus or fistula was seen below 10 years old age. 4) The prevalent side of this anomaly was right side in 19 cases, left side in 29 cases and bilateral 2 cases, and so left side was more common than right. 5) The clinical presentation was characterized by the lesion along anterior border of sternocleido muscle, non-tender palpable mass were 28 cases, drainage sinus 18 cases, recurrent abscess and drainage 5 cases and intermittent ear discharge 1 case. 6) The mean size of cyst was about 4cm that containing turbid white-yellowish fluid but discharge from sinus or fistula was clear mucoid. 7) The culture of cyst fluid was no bacteria, but 2 cases showed staphyloccoci suggesting secondary infection. 8) The surgical procedure were complete excision of cyst 32 cases, sinus excision 11 cases, fistula excision 6 cases and I&D 1 case. And the recurrent 1 case was that fistula tract could not be identified due to severe scar from previous several operations.

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Effect of Continuous Treatment of Mixed Organic Fertilizer With Food Waste on the Growth of Lettuce

  • Yosep Kang;Ho-Jun Gam;Eun-Jung Park;Seong-Heon Kim;Sang-Mo Kang;In-Jung Lee
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.111-111
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    • 2022
  • According to data from the Ministry of Environment, food waste accounted for 27% of the nation5 s household waste in 2020, and 4.67 million tons of food waste is being discharged per year. According to the Food Waste Direct Landfill Prohibition Act, food waste must be incinerated, composted, fodder, and decomposed before landfilling. The cost of incineration and landfilling of food waste is considerable. Therefore, through the process of turning food waste into fertilizer, we are going to investigate the limit of crop application and the change in the growth of crops during continuous use of food waste fertilizer. This study investigated the growth of lettuce such as shoot length, root length, leaf number, fresh weight, and dry weight after treating lettuce with food waste dry powder mixed fertilizer. The experiment was carried out continuously in 2021 (1st year) and 2022 (2nd year), and the treatment groups were set to No Treatment (NT), Chemical Fertilizer (CF), Mixed Fertilizer (MF×1), and Mixed Fertilizer×2 (MF×2), was repeated 3 times. As a result of the 1st year growth survey, there was no significant difference between NT and CF in the case of shoot length, but MF×1 and MF×2 were significantly decreased compared to NT. Root length was not significantly different in all treatment groups. As for the leaf number, there was no significant difference between NT and MF×1, but CF and MF×2 were significantly decreased compared to NT. In fresh weight, MF×1 and MF×2 were significantly decreased compared to NT, and in the case of dry weight, there was no significant difference between NT, MF×1, and MF×2. As a result of the 2nd year growth survey, there was a significant difference in CF and MF×2 in leaf number, but there was no significant difference in all treatment groups with respect to shoot length, root length, fresh weight, and dry weight. Through continuous additional research, it is necessary to confirm the change in soil composition and the growth of crops due to food waste fertilizer treatment.

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수세미오이 발효추출물의 항산화 및 피부암 억제 효과 (Enhancement of Antioxidant and Skin Cancer Inhibition Effects by Fermented Luffa aegyptiaca Extract)

  • 김송이;감다혜;김준희;염서희;박재현;김진우
    • 한국산학기술학회논문지
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    • 제22권3호
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    • pp.408-414
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    • 2021
  • 본 연구의 목적은 수세미오이 추출물을 유산균을 이용한 발효를 통해 항산화 활성과 함께 생체 활성 물질의 생산을 중대하고 자외선 흡수 및 피부 흑색종 세포 성장 억제를 강화하여 피부암 예방 효과를 향상시키는 데 있다. 수세미오이 발효추출물의 총 폴리페놀(TPC)과 항산화 활성도가 30.23 mg GA/g DM와 45.12%로 열수추출물보다 약 1.4배 높은 수준으로 확인되었다. 자외선 흡수율에 있어 발효추출물은 열수추출물보다 1.5배 높은 53.9%의 흡수율을 보였는데 발효를 통해 증가된 TPC에 의해 UV 흡수가 증가했다는 결론을 도출하였다. 항암효과에 있어 발효추출물과 열수추출물에서 각각 1.0 와 2.0 mg/mL에서 피부 흑색종세포에 대한 성장저해 효과가 나타나 추출물 발효에 따른 항암효과가 증가했음을 알 수 있었다. 발효추출물의 자외선 흡수율에 있어 열수출물보다 2.4배 높아 피부암 예방효과가 예상되며, 수세미오이 발효를 통해 항산화, 자외선차단과 피부암 저해 효과를 가지는 화장품, 식품 및 의약품 소재 개발 가능할 것으로 사료된다.

동의보감(東醫寶鑑)을 위주(爲主)로한 비만의 원인(原因), 증상(症狀), 치료법(治療法) 연구 (A Study on etiological factors, symptoms of a disease, and treatments of obesity based on Dong-Yi Bo Gam)

  • 김석;진승희;김태희
    • 대한한의학회지
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    • 제19권2호
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    • pp.125-136
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    • 1998
  • This study is on the etiological factors of the obesity, symptoms of a disease caused by the etiological factors and the method of medical treatment resulted from symptoms of a disease, it is based on Dong-Yi Bo Gam. The conclusion of this study is as follows. 1. The final metabolic of fat is depend on the defensive energy. The shape of fatty layer is changed by the point where the defensive energy is replenish or not. So 'Goin(暠人)' 'Bein(肥人)' and 'Yuckin(肉人)' is made a discriminated and there is defferent between 'Besudaeso(肥瘦大小)' and 'Herlqidaso(血氣多少)'. 2. Etiological factors of obesity is ; essential substance from cereals overcome the primodial energy, spleen and stomach are strong at once, spleen and stomach are weak at once, spleen is disturbed by evil energy, retention of phlegm and fluid, muscle is weak, blood is excess but energy (qi)is weak, hua-sid(華食) eating the sweat food very often, a rich fatty diet. 3. To investigate each syndrome as etiological factons, essential substance from cereals overcome primodial energy is divided into two case: one is the food increase itself because of the weakness of stomach energy (qi), the other is not to digest the food because liver overact spleen by seven emotion. The obesity because of strengthen of the spleen and stomach at once do not feel hungry very well and spleen and stomach do not damaged easily by overacting. The obesity because of weakness of spleen and stomach at once, and disturbace in spleen cause by evil energy, gain the weight even if they eat food a little. Also it is hard to move four limbs. Weakness of muscle is weakness of spleen and stomach. Weakness of muscle is caused by weakness of spleen and stomach. That is the case of faining the weight because of eating food with an empty stomach. The obsity caused by retention of fluid has intestine rumbling and gain the weight suddenly. 4. The method of medical treatment fallowing to the etiological factors: The food is inclined to increase itself caused by weakness of stomach energy, In case of the obseity caused by this phenomenon. We can use Decoction for Reinforcing Middle wanner and Replenishing Qi(補中益氣湯), five tastes il-going-san(左味異功散) and so on. The method of medical treatment on obsity caused by strengthen of spleen and stomach is not referred yet. But we must investigate about using peptic powder(平胃散), ji-chul-huan(枳朮丸) for strengthen of stomach qi (胃氣). If the obesity appear caused by weakness of spleen and stomach and disturbance in spleen as to evil energy, and in the same time stomach qi is weak, we can use li-gong san(異功散). If not only obesity but also indigestion, we can use Decoction for naurishing the stomach and promotion eating(養胃進食湯). If not only obesity but also weakness of spleen and stomach, we can use Decoction for Reinforcing Middle warmer and replenishing Qi(補中益氣湯). The energy being weak, we can use Decoction for six noble drugs(六君子湯). If the obesity appear because of retention of fluid, we can use sin-chul-huan(神朮丸). On the obesit, caused by excess of blood and weakness of qi(血管氣虛), there is not method of mectical treatment yet, but the method of medical treatment that we count of first important maybe to invigorate the spleen and the lung qi and to disperse and recitify the depressed liver energy(疏肝利氣). The method of medical treament about the obesity caused by a rich fatty diet is not mentioned yet, but it is important to improve the lifestyle of food and we think that invigorate the spleen, and the lung-qi(補疏肝氣) and disperse and recitify the depressed liver-energy (??肝利機) amy count of first important. 5.There is useful medicine for weight down for example Herb tea(茶), red bean, wax gourd, etc. 6.The etiological factors of the obesity that revive frequently is weakness of qi(氣虛), from 形成氣衰, deficiency of yang, hasty of qi, damp and so on. The symptoms and sign of a disease that revive frequently to the obesity is appoplexia(中風), leucorrhea, reddish and whitish turbid, feeling of fullness in the upper abdomen, diabetes and so on.

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Fluorescent In Situ Hybridization방법으로 분석한 소양호 세균 군집 구조의 계절적 변화 (Seasonal Changes of bacterial community analysed by fluorescent in situ hybridization method in Lake Soyang)

  • 홍선희;안태석
    • 미생물학회지
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    • 제34권3호
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    • pp.169-174
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    • 1998
  • 소양호에서 세균군집의 계절적, 수심별 변화를 파악하고자 총세균수와 EUB338, ALG1b, BET42a, GAM42a와 CF probe 등 fluorescent rRNA target oligonuvleotide probe와 반응하는 세균 개체수를 측정하였다. 총세균수는 $0.5{\sim}2.01{\times}10^6cells{\cdot}ml^{-1}$이였으며, 2 m와 5 m 수층에서 높게 나타났다. 총세균수에 대한 Eubacteria의 비율은 22~100%이였고, Proteobacteria ${\alpha}$-group은 Eubacteria의 2.6~66.7%, ${\beta}$-group은 4.5~53.5%, ${\gamma}$-group은 4.6~76.7%, 그리고 Cytophage-Flavobacterium group은 2.1~35.9%이였다. 또한 세균군집은 계절별, 수심별로 다양한 변화를 보여, 겨울철은 ${\beta}$-group이, 봄철과 초여름은 ${\gamma}$-group이, 여름철은 ${\alpha}$-group이 우점하였고, Cytophage-Flavobacterium group이 특정적으로 우점하는 시기는 없었다. 이러한 세균 군집 구조의 분포로 계절별, 수심별로 호수에 대한 독특한 특징을 알 수 있었다.

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폴리페놀 함량과 항산화력에 따른 피땅콩 겉껍질의 최적 추출 조건 확립과 항비만 기능성 평가 (Polyphenols in peanut shells and their antioxidant activity: optimal extraction conditions and the evaluation of anti-obesity effects)

  • 감다혜;홍지우;염서희;김진우
    • Journal of Nutrition and Health
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    • 제54권1호
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    • pp.116-128
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    • 2021
  • 본 연구에서는 초음파를 이용하여 농업 부산물인 피땅콩 겉껍질의 추출 조건을 최적화하고 추출물의 항산화능과 항비만 기능성을 측정하였다. 실험설계는 CCD를 이용하였고 독립 변수인 추출 시간, 추출 온도, 에탄올 농도에 따라 TPC, TFC와 RSA를 종속 변수로 설정하여 이들의 값을 최대로 하는 공통 조건을 예측하였다. 각각의 모델식의 R2값은 0.85 이상으로 적합하였으며, 추출 조건으로 추출 온도와 에탄올 농도가 TPC 및 TFC에 유의적인 영향을 주는 것을 알 수 있었다. 반면 RSA는 에탄올 농도에 영향을 많이 받는데, 에탄올 농도가 높을수록 RSA가 높아지다가 최고점을 보인 후 다시 감소하는 경향을 나타내었다. 최적 추출 조건인 추출 시간 35.8분, 추출 온도 82.7℃와 에탄올 96.0%에서 제조한 추출물의 TPC, TFC와 RSA의 실측치는 예측치와 유사한 값을 나타내어 회귀 방정식이 신뢰할 수 있음을 확인하였다. 추출물의 항비만 기능성 평가를 위한 GIA와 LIA 실험 결과는 각각 86.4%와 78.5%로 열수 추출물보다 높게 나타나 초음파 추출에 의한 생리활성 물질 추출이 효과적임을 알 수 있었다. 이로써 농업 부산물인 피땅콩 겉껍질로부터 고부가가치 생리활성 물질 생산 가능성을 확인하였고 식품, 화장품 및 의약품용 항산화와 항비만 기능성 소재 생산에 있어 원료 공급비용 절감과 효율적인 추출 공정 확보로 산업 전반에서 가격 경쟁력 확보와 환경문제 해결에 기여할 것으로 사료된다.

사이버불링 발생과 정보매체활용 간의 상관분석 - 인터넷과 휴대전화 사용을 중심으로 (The Corelation Research between Cyberbullying and Information Media Use - With Focus on Internet and Mobile Phone Use)

  • 김봉섭;박종선;감동은;진상기
    • 컴퓨터교육학회논문지
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    • 제16권5호
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    • pp.17-29
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    • 2013
  • 청소년들에게 사이버불링은 심각한 위해 요소로 작용하고 있지만 사안의 심각성과 중요성에도 불구하고 학문적인 접근과 시도는 아직 초기 단계이다. 이에 따라 본 연구에서는 전국 초 중 고등학생 1,112명을 대상으로 설문조사를 실시하였다. 조사 결과 청소년들 사이에 인터넷 불링 가해경험은 유형별로 20.3%에서 39.0%, 피해경험은 11.0%에서 23.4%, 휴대전화 불링 가해경험은 15.9%에서 44.1%, 피해경험은 5.5%에서 21.8%인 것으로 나타났다. 사이버불링 가해 경험에 영향을 미치는 요인으로는 인터넷의 경우 성별, 학업스트레스, 인터넷 접근성, 익명성, 인터넷 이용시간 등인 것으로 조사되었다. 휴대전화의 경우에는 학교급별, 학업스트레스, 휴대이동성, 익명적 이용가능성, 휴대전화 이용시간 등이 휴대전화 불링에 영향을 미치는 것으로 나타났다. 마지막으로 인터넷 불링과 휴대전화 불링과의 관계를 살펴본 결과 인터넷 불링 가 피해 경험과 휴대전화 불링 가 피해 경험은 서로 관련이 있는 것으로 나타났으며, 특히 인터넷 불링 가해경험과 휴대전화 불링 가해경험, 인터넷 불링 피해경험과 휴대전화 불링 피해경험은 상당한 관련이 있는 것으로 조사되었다.

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중점기술 선정을 위한 관계분석형 R&D 포트폴리오 방법 (Relationship-type R&D Portfolio Method for Selection of Core Technology)

  • 감혜미;서민우;김찬수
    • 한국산학기술학회논문지
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    • 제19권6호
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    • pp.677-682
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    • 2018
  • 관계분석형 R&D 포트폴리오 방법은 중점기술의 선정기준이 독립적일 경우 각 선정기준의 고유한 목적과 특성을 반영하여 중점기술을 선정하는 방법이다. 본 연구는 중점기술을 도출하기 위한 방법으로 관계분석형 R&D 포트폴리오 방법을 제시하고 선정기준과 분석지표간의 상관관계 분석하는 1단계, 각 선정기준에 최적으로 부합하는 포트폴리오 매트릭스를 구성하는 2단계, 중점기술을 도출하는 3단계로 나누어 방법론을 적용하는 과정을 서술하였다. 본 연구에서는 중점기술을 선정하기 위한 4대 선정기준과 기술수준, 경제성, 기술성을 파악하기 위한 분석지표간의 상관관계를 HoQ를 응용한 표로 작성하였다. 상관관계표를 바탕으로 각 선정기준을 최적으로 만족하기 위해 고려해야 할 분석지표를 도출하였으며, 도출된 분석지표와 선정기술을 두 축으로 포트폴리오 매트릭스를 구성하였다. 4대 기준을 모두 충족하는 충족형 포트폴리오 P0와 4대 선정기준의 고유한 특성을 반영하여 각 선정기준을 효과적으로 충족하는 포트폴리오 P1~P4를 구성하여 중점기술을 도출하였다. 선정된 중점기술은 명세기반의 키워드 분석 등의 과정을 거쳐 미래 안보환경에 대응하기 위한 중점분야 선정에 활용될 수 있다.

반응표면분석법을 이용한 미강으로부터 항산화 활성 및 생리활성물질의 초음파 추출조건 최적화 (Optimization of Extraction Conditions of Antioxidant Activity and Bioactive Compounds from Rice Bran by Response Surface Methodology)

  • 감다혜;조재민;정현진;김진우
    • 공업화학
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    • 제29권6호
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    • pp.726-733
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    • 2018
  • 벼의 도정 부산물을 미강이라고 하며 매년 40-60만 톤의 미강이 도정 부산물로 생산된다. 미강은 일부 가축사료로 사용되거나 버려지는 실정으로 미강으로부터 생리활성물질과 같은 고부가가치 물질 생산을 통한 도정 부산물 활용이 필요하다. 따라서 본 연구에서는 통계학적 최적화를 통한 미강으로부터 총 폴리페놀 함량(TPC), 총 플라보노이드 함량(TFC) 및 라디칼 소거능 활성(EDA) 증대를 위해 초음파 추출의 주요 공정조건인 추출시간($X_1$), 추출온도($X_2$), 에탄올 농도($X_3$)를 중심합성계획법을 이용하여 최적화하였다. 중심합성계획법을 통해 최적조건을 도출한 결과 추출온도 $94.9^{\circ}C$, 추출시간 41.6 min, 에탄올 농도 74.0% (v/v) 조건에서 TPC 2.78 mg GAE/g DM, TFC 1.63 mg QE/g DM, EDA 42.86%를 얻을 수 있었다, 이를 통해 초음파 추출공정은 $100^{\circ}C$ 이하의 저온 추출 조건에서 42 min의 짧은 추출을 통해 미강으로부터 생리활성 및 항산화 화합물의 추출에 효과적임을 확인하였으며 미강 추출물의 식품첨가 및 화장품 원료로서의 이용 가능성을 확보하였다.

진동, 파동치료에 관한 국내 연구 동향 (An Overview on Vibration or Wave Therapy in Korea)

  • 이재흥;백지유;장성진;필감매
    • 대한의료기공학회지
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    • 제20권1호
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    • pp.15-67
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    • 2020
  • Objective : The purpose of this study is to identify the trends of vibration(or wave) therapy in Korea, to actively utilize vibration(or wave) therapy, and to help research activities of vibration therapy in Korean Medicine. Methods : The following Korean words "진동기", "진동요법", "진동운동", "진동치료", "파동요법", "파동운동", "파동치료" were searched on three specialized search sites (RISS, NAL, DBpia). Trends of vibration therapy were analyzed through the selected researches suitable for this study among these searched researches in an overview format. Results : 1. A total of 8,116 studies were searched and a total of 365 studies were finally selected 2. From 2000 to 2019, when research began to increase in earnest, there were 17.45±10.28 studies per year, and the AGR(Average Annual Growth Rate) was 11.92%. 3. In the main field of research, the 'Medicine and Pharmacy' was the largest with 147(40.16%) studies. In the Middle Field, the 'Kinesiology' was the largest with 99(27.05%) studies. In the study design, 'RCT(Randomized Controlled trial)' was the largest with 138(47.75%) studies. In the Age Group, 'Youth' was the largest with 126(48.84%) studies. 4. The average of the number of participants was 24.90±17.44. 5. The most used Intervention was the 'WBV(Whole Body Vibration)' with 177(61.25%) studies. 6. The average of Intervention Period was 5.99±4.14 weeks, while the maximum was 36 weeks. 7. The journal that published the most research papers is 'K. J. of Sports Science(체육과학연구;13)', and the society is 'Rehabilitation Engineering And Assistive Technology Society of Korea(한국재활복지공학회; 14)'. The University that published the most dissertations is 'Sahmyook University(11)'. 8. The authors who published the most studies are Ju-Hwan O(8) as the main author and Tae Kyu Kwon(18) as the co-author (including the thesis Director). In an integrated analysis of the authors and co-authors, Tae Kyu Kwon published the most numerous studies(19) Conclusions : 1. The study of vibration or wave therapy has been increasing noticeably every year. 2. The major academic Fields studying vibration or wave therapy are the 'Kinesiologic Field', 'Physical Therapy Field', and 'Biomedical Engineering Field'. 3. The most chosen method of study design on vibration or wave treatment was 'RCT', and there was no significant change in the annual presentation rate. 4. Types of vibration or wave therapy could be classified as 'LVS(Local Vibration Stimulation)', 'WBV(Whole Body Vibration)', 'MV(Micro Vibration)', 'BV(Bio Vibration)' and 'SWV(Sound Wave Vibration)', and the study on Whole Body Vibration is most active. 5. Most of the studies of vibration or wave therapy were on musculoskeletal systems, but there were very few studies on internal diseases.