• Asian-Australasian Journal of Animal Sciences
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• v.27 no.10
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• pp.1373-1380
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• 2014

The thyroid hormone responsive protein (THRSP) gene is a functional gene that can be used to indicate the fatty acid compositions. This study investigates the relationships of exonic single nucleotide polymorphisms (SNPs) in the THRSP gene and fatty acid composition of muscle fat and marbling score in the 612 Korean cattle. The relationships between fatty acid composition and eight SNPs in the THRSP gene (g.78 G>A, g.173 C>T, g.184 C>T, g.190 C>A, g.194 C>T, g.277 C>G, g.283 T>G and g.290 T>G) were investigated, and according to the results, two SNPs (g.78 G>A and g.184 C>T) in exon 1 were associated with fatty acid composition. The GG and CC genotypes of g.78 G>A and g.184 C>T had higher unsaturated fatty acid (UFA) and monounsaturated fatty acid (MUFA) content (p<0.05). In addition, the $ht1^*ht1$ group (Val/Ala haplotype) in a linkage disequilibrium increased MUFAs and marbling scores for carcass traits (p<0.05). As a result, g.78 G>A and g.184 C>T had significantly relationships with UFAs and MUFAs. Two SNPs in the THRSP gene affected fatty acid composition, suggesting that GG and CC genotypes and the $ht1^*ht1$ group (Val/Ala haplotype) can be markers to genetically improve the quality and flavor of beef.

• Toxicological Research
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• v.24 no.2
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• pp.109-112
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• 2008

The G184C and G134A single nucleotide polymorphisms(SNPs) of the CYP1A1 gene result in Ala62Pro and Gly45Asp substitutions, respectively. Here, we tested whether these SNPs are associated with an alteration in lung cancer incidence. We examined 80 Korean subjects with lung cancer and 240 age- and sex-matched controls. For each subject, the CYP1A1 gene was PCR amplified and sequenced. We observed that the odds ratio(OR) for lung cancer was 3.37 higher in subjects with the G184C polymorphism than in controls(95% confidence interval(CI), $0.89{\sim}12.73$, P=0.07). In contrast, the OR for lung cancer was 1.23 in subjects with the G134A polymorphism compared to controls(95% CI, $0.68{\sim}2.20$, P=0.49). The G184C polymorphism exacerbated the effects of smoking on lung cancer development. Gene-smoking interaction analyses revealed that past or present smokers with the G184C polymorphism had a higher incidence of lung cancer(OR, 24.72; 95% CI, $4.48{\sim}136.31$; P<0.01) than control smokers(OR, 6.65; 95% CI, $2.72{\sim}16.28$; P<0.01). However, there was only a slight difference in the ORs for lung cancer between control smokers and smokers with the G134A polymorphism. These findings suggest that the G184C polymorphism, but not the G134A polymorphism, is associated with an increased risk of lung cancer.

• Journal of Life Science
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• v.25 no.11
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• pp.1197-1203
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• 2015

Salmonella Typhimurium (ST) JOL389 and χ3339 are strong virulent strains against mouse. ST χ8554 is derived by deletion of the asd gene from ST χ3339. Plasmid pMMP184 carrying a ghost cassette was transformed into ST χ8554, and ST χ8554 ghost cells were prepared and administrated via the oral route to BALB/c mice. Change in the amount of total IgG was not elicited to boosting of single ST χ8554 ghost cells, but the content was increased from 6 weeks after the 3^rd administration. However, when the ST JOL389 ghost cells is administered together with ST χ8554 ghost cells, the content of total IgG was increased in 2 weeks post primary administration. It was found that the content of total IgG of the group mixed with ST JOL389 ghost cells showed an increased value of 8 times or more at 10 weeks when compared with the group of ST χ8554 ghost cells. The content of IgG1, IgG2a, and sIgA in both groups increased from 4 weeks postprimary administration. As a challenge test of virulent ST χ3339, χ8554 (pMMP184) and χ8554 (pMMP184)/JOL389 ghost cell groups showed protection of 50% or more when compared to the control group. These results suggest that the preparation of combined ghost cells from a strong virulent ST increases immunity more than a single strain.

• Proceedings of the Korean Magnestics Society Conference
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• 2008.12a
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• pp.184.1-184.1
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• 2008

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.10a
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• pp.184-184
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• 2003

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 1987.04a
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• pp.184-187
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• 1987

The method of Conjugate Gradient(C.G.M) is applied to the solution of current distribution from body of revolution (B.O.R).Using the C.G.M it is possible to analyze electrically large arbtrarily oriented B.O.R. The fundamental differences between C.G.M and moment method are outlined. This method converges for any initial guess and this techniqe gurantees a monotonic convergence. Numerical results are presented for electromagnetic case which show good agreement with moment solution.

• Preventive Nutrition and Food Science
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• v.16 no.2
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• pp.184-188
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• 2011

The melatonin, total polyphenol contents, and DPPH radical scavenging activity were determined in alfalfa, chicory, rape, red kale and sunflower after germination for four days at $24{\pm}0.1^{\circ}C$. Compared with seeds, melatonin content was increased in all sprouts, at the highest level in red kale (2,502.9 pg/g, 5.6 times higher than seed) followed by rape (2,430.1 pg/g), chicory (2,037.7 pg/g), alfalfa (1,160.8 pg/g) and sunflower (768.2 pg/g) sprout, however, the addition of tryptophan (0.5 mM), the precursor of melatonin synthesis, did not show any desirable effect. Both polyphenol content and DPPH radical scavenging activity were substantially increased in chicory (8.7 mg/g, 66%), rape (10.7 mg/g, 51%) and red kale (11.0 mg/g, 53%) sprouts, but not in alfalfa and sunflower sprouts. Melatonin content per gram polyphenol (ng/g) was also increased in all sprouts through germination. Germination was effective in increasing melatonin in all seeds tested, while its effect on polyphenol content and DPPH radical scavenging activity was species dependent.

• Journal of Animal Science and Technology
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• v.63 no.1
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• pp.194-197
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• 2021

Salmonella enterica is a representative foodborne pathogen in the world. The S. enterica strain K_SA184 was isolated from the lamb (Ovis aries), which was collected from a local traditional market in South Korea. In this study, the S. enterica strain K_SA184 was sequenced using PacBio RS II and Illumina NextSeq 500 platforms. The final complete genome of the S. enterica strain K_SA184 consist of one circular chromosome (4,725,087 bp) with 52.3% of guanine + cytosine (G + C) content, 4,363 of coding sequence (CDS), 85 of tRNA, and 22 of rRNA genes. The S. enterica strain K_SA184 genome includes encoding virulence genes, such as Type III secretion systems and multidrug resistance related genes.

• Korean Journal of Agricultural and Forest Meteorology
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• v.17 no.2
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• pp.173-181
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• 2015

Fluxes of carbon dioxide ($CO_2$) were measured above crop canopy using the Eddy Covariance (EC) method, and emission rate of methane ($CH_4$) was measured using Automatic Open/Close Chamber (AOCC) method during the 2012-2013 barley and rice growing season in a barley-rice double cropping field of Gimje, Korea. The net ecosystem exchange (NEE) of $CO_2$ in the paddy field was analyzed to be affected by crop growth (biomass, LAI, etc.) and environment (air temperature, solar radiation, etc.) factors. On the other hand, the emission rate of $CH_4$ was estimated to be affected by water management (soil condition). NEE of $CO_2$ in barley, rice and fallow period was -100.2, -374.1 and $+41.2g\;C\;m^{-2}$, respectively, and $CH_4$ emission in barley and rice period was 0.2 and $17.3g\;C\;m^{-2}$, respectively. When considering only $CO_2$, the barley-rice double cropping ecosystem was estimated as a carbon sink ($-433.0g\;C\;m^{-2}$). However, after considering the harvested crop biomass ($+600.3g\;C\;m^{-2}$) and $CH_4$ emission ($+17.5g\;C\;m^{-2}$), it turned into a carbon source ($+184.7g\;C\;m^{-2}$).

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.184-184
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• 2010

ITO의 전극 패턴에 따른 유기 광기전력 소자의 전기적 특성에 대해서 연구하였다. 소자의 구조는 ITO/PEDOT:PSS(90nm)/CuPc(20nm)/$C_{60}$(40nm)/LiF(0.5nm)/Al(100nm)이고, PEDOT:PSS는 스핀 코팅한 후 $120^{\circ}C$에서 20분간 건조시켰으며, 유기물은 열증착을 하여 제작하였다. ITO 전극의 패턴을 corss-bar type과 island type으로 하여 소자의 특성을 비교하였다. 광원은 500W xenon lamp를 사용하였고, optical density filter로 광원의 세기를 조절하였으며, AM 1.5G의 스펙트럼을 조사하였다. PEDOT:PSS 층을 사용함으로서 유기 광기전력 소자의 효율, 단락 전류, 그리고 개방 전압의 향상을 얻을 수 있었다. ITO 전극 패턴에 따른 광기전력 소자의 특성은 cross-bar type에 비하여 island type의 구조에서 유기 광기전력 소자의 효율이 34% 감소하였다.