• Korean Journal of Food Science and Technology
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• v.36 no.6
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• pp.959-967
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• 2004

To screen probiotic lactic acid bacteria with potent adhesive property on human colonic mucosa, colonic mucin-binding assay was introduced. This colonic mucin-binding assay actually measures the binding activity of surface lectin-like protein (SLP) on colonic mucin, and the optimal conditions were examined. The optimal pH for colonic mucin coating on plate wells was 4.8, and ${\times}24,000$ diluted solution of commercially available horseradish peroxidase (HRP) conjugated streptoavidin yielded good results, for rapid screening, $5.0\;{\mu}g/mL$ of biotinylated SLP from lactic acid bacteria was optimal, and optimal scintillation time of 3,3',5,5'-tetramethyl benzidine (TMB) was 10 min. These conditions were useful for both rapid selection and quantitative analysis of lactic acid bacteria that have high adhesion property to human intestinal tract. Among 50 strains of lactic acid bacteria, including 32 type culture strains and 18 isolated strains from infant feces, Lactobacillus species FSB-1 isolated from kimchi showed the highest binding activity to colonic mucin. From taxonomical viewpoints based on morphological study, physico-biochemical study, partial 16S rDNA seguencing, and phylogenetic analysis, L. species FSB-1 was identified as Lactobacillus brevis.

• Journal of Applied Biological Chemistry
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• v.55 no.1
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• pp.55-59
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• 2012

We designed a new rapid detection method for volatilized formaldehyde from wood. The process was installed with volatilizing and collecting parts in an incubator. For rapid sampling of formaldehyde from wood, we pulverized the wood to sawdust, and used 0.15-2.0 mm particles for the tests. The highest sampling rate (94.8%) was obtained at 40 mL/min flow rate and $100^{\circ}C$. Under the optimized condition, we could collect the volatilized formaldehyde with good recovery rate. The developed method was applied to the monitoring of the formaldehyde from wood, and the measured concentrations were 0.7-4.6 ${\mu}g/g$ from natural wood, 5.9-12.3 ${\mu}g/g$ from preserved wood, and 5.9-211.5 ${\mu}g/g$ from chemical adhesive processed wood. From the results, we identified natural wood sawdust and chemically processed wood (medium density fiberboard, high density fiberboard, particle board) by the formaldehyde contents except preserved wood.

• Applied Chemistry for Engineering
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• v.5 no.5
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• pp.851-856
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• 1994

Compatibility and viscoelasticity in non-solvent type pressure sensitive adhesive of styrene-isoprene-styreno(SIS) block copolymer with tackifier resin were investigated. In the isoprene phase of SIS block copolymer, it was found that it's compatibility with $C^5$ petroleum resin was good, but that with Coumarone-indents resin was not so good. The magnitudes of peel strength, tack, and holding power were as follows : $C^5$ petroleum resin>rosin ester resin>coumarone-indene resin. The tackifier resin with good compatibility in rubber phase was also effective. However, with plateau modulus value of $1{\times}10^6-3{\times}10^6dyn/cm^2$, the effect of pressure sensitive adhesives was excellent.

• Journal of Environmental Health Sciences
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• v.44 no.3
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• pp.238-243
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• 2018

Objectives: The purpose of this study was to determine skin adhesion rate of children's modeling clay for exposure assessment. Methods: Children's modeling clays were classified into 10 categories as PVA clay, PVA soft clay, starch-based clay, foam clay, rubber clay, oil clay, muddy clay, terra clay, paper clay and slime. A total of 26 children's clay goods was selected. Moisture content (%) and hardness of clays were measured. Five adults aged 20 to 25were recruited for experiment. Gravimetric difference of modeling clay was determined after 3 minutes playing time. Skin adhesion rate ($g/min/cm^2$) was estimated bythe amount of skin adhesion per minute (g/min) and each individual's palm surface area ($cm^2$). Results: Twenty four of the 26 children's modeling clay products were adhesive to skins. Two products of foam and rubber clay were not adhered to skin. For the 24 products, the average skin adhesion rate was $5.5{\times}10^{-4}{\pm}4.0{\times}10^{-4}g/min/cm^2$. The highest skin adhesion rate was $1.3{\times}10^{-3}{\pm}4.4{\times}10^{-4}g/min/cm^2$ for paper clay. The lowest skin adhesion rate was $4.6{\times}10^{-5}{\pm}1.1{\times}10^{-4}g/min/cm^2$ for oil clay. The skin adhesion rate was increased with increase of moisture content. Adhesion rates of some clays were varied by person and testing trials. Conclusion: The study determined skin adhesion rate of children's modeling clay. The adhesion rate is useful for exposure and risk assessments and setting safety guideline to protect children's health.

• Korean Chemical Engineering Research
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• v.43 no.4
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• pp.495-502
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• 2005

Copper was plated on the tungsten substrate by use of a direct copper electroless plating. The optimum deposition conditions were found to be with a concentration of $CuSO_4$ 7.615 g/L, EDTA of 10.258 g/L, and glyoxylic acid of 7 g/L, respectively. The solution temperature was maintained at $60^{\circ}C$. The pH was varied from 11.0 to 12.8. After the deposition, the properties of the copper film were investigated with X-ray diffractometer (XRD), Field emission secondary electron microscope (FESEM), Atomic force microscope (AFM), X-ray photoelectron spectroscope (XPS), and Rutherford backscattering spectroscope (RBS). The best deposition condition was founded to be the solution pH of 11.8. In the case of 10 min deposition at the pH of 11.8, the grain shape was spherical, Cu phase was pure without impurity peak ($Cu_2O$ peak), and the surface root mean square roughness was about 11 nm. The thickness of the film turned out to be 140 nm after deposition for 12 min and the deposition rate was found to be about 12 nm/min. Increase in pH induced a formation of $Cu_2O$ phase with a long rectangular grain shape. The pH control seems to play an important role for the orientation of Cu in electroless deposition. The deposited copper concentration was 99 atomic percent according to RBS. The resulting Cu/W film yielded a good adhesive strength, because Cu/W alloy forms during electroless deposition.

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.4
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• pp.579-589
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• 2007

The objective of this study was to compare the shear bond strengths of five adhesive systems to the enamel and dentin of primary and permanent teeth. Fifty noncarious primary and fifty permanent teeth were collected and stored in an 0.1% thymol solution at room temperature after extraction. The tested adhesives were: Adper Scotchbond Multi-purpose Plus Adhesive (SM) Adper Single bond 2 (SB), Clearfil SE Bond (SE), Adper Prompt L-Pop (PL), GBond (GB). For the shear bonding test, the labial and lingual surfaces of primary and permanent teeth were used. To obtain a flat surface, the labial and lingual surfaces of the teeth were sanded on $SiO_2$ with number 600 grit and then divided into 20 groups of 10 surfaces each. All samples were theromocycled in water $5^{\circ}C$ and $55^{\circ}C$ for 1000 cycles. The results were as follows: 1. For primary enamel, shear bond strengths of SM and SB were significantly higher than that of SE and also SM, SB, and PL were higher than GB(p<0.05). 2. For primary dentin, there were no significant differences among the shear bond strengths of any other bonding systems except difference between SE and GB. 3. For permanent enamel, SB showed significantly higher mean shear bond strength than those of any other bonding systems(p<0.05). 4. For permanent dentin, SM showed significantly higher mean shear bond strength than that of PL and GB(p<0.05). 5. Between the primary enamel and dentin, there were significant differences in SM, SB, and GB, whereas there was statistically significant difference in PL between the permanent enamel and dentin(p<0.05). 6. Between the primary and permanent teeth on enamel, there were no significant differences among all bonding systems, whereas there were statistically significant differences in SM and SB between the primary and permanent teeth on dentin(p<0.05).

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4807-4814
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• 2012

Purpose: The chemoresistance of human hepatocellular carcinoma (HCC) to cytotoxic drugs, especially intrinsic or acquired multidrug resistance (MDR), still remains a major challenge in the management of HCC. In the present study, possible mechanisms involved in MDR of HCC were identified using a 5-fluorouracil (5-FU)-resistant human HCC cell line. Methods: BEL-7402/5-FU cells were established through continuous culturing parental BEL-7402 cells, imitating the pattern of chemotherapy clinically. Growth curves and chemosensitivity to cytotoxic drugs were determined by MTT assay. Doubling times, colony formation and adherence rates were calculated after cell counting. Morphological alteration, karyotype morphology, and untrastructure were assessed under optical and electron microscopes. The distribution in the cell cycle and drug efflux pump activity were measured by flow cytometry. Furthermore, expression of potential genes involved in MDR of BEL-7402/5-FU cells were detected by immunocytochemistry. Results: Compared to its parental cells, BEL-7402/5-FU cells had a prolonged doubling time, a lower mitotic index, colony efficiency and adhesive ability, and a decreased drug efflux pump activity. The resistant cells tended to grow in clusters and apparent changes of ultrastructures occurred. BEL-7402/5-FU cells presented with an increased proportion in S and G2/M phases with a concomitant decrease in G0/G1 phase. The MDR phenotype of BEL-7402/5-FU might be partly attributed to increased drug efflux pump activity via multidrug resistance protein 1 (MRP1), overexpression of thymidylate synthase (TS), resistance to apoptosis by augmentation of the Bcl-xl/Bax ratio, and intracellular adhesion medicated by E-cadherin (E-cad). P-glycoprotein (P-gp) might play a limited role in the MDR of BEL-7402/5-FU. Conclusion: Increased activity or expression of MRP1, Bcl-xl, TS, and E-cad appear to be involved in the MDR mechanism of BEL-7402/5-FU.

• Applied Chemistry for Engineering
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• v.10 no.4
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• pp.523-530
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• 1999

Acrylic pressure-sensitive adhesive has been made utilizing organic solvents, but nowadays it is made by solvent-free system due to environmental problems. In this study, emulsion polymerization were carried out at $40^{\circ}C$ with methacrylic acid(MAA), n-butyl acrylate(n-BA) and 2-ethylhexyl acrylate(2-EHA) as monomers in the presence of anionic(sodium dodecyl sulfate, SDS) and nonionic(ethylene oxide types) surfactant mixtures. The overall conversion of the polymerization reaction in a mixed surfactant system was found to be higher than that in a single surfactant system. Emulsion stability in mixed or anionic surfactant systems was found to be over 12 week, which was better than that in nonionic surfactant system. Emulsion particle size decreased as surfactant content increased. The Tg and molecular weight of emulsion polymer were inependent of the type, the amount and the mixing ratio of surfactant. Based on the results of stability and peel strength, the optimum nonionic surfactant ratio in total 4 g of surfactant mixture systems is found to be 40~60% by weight where the nonionic surfactant has 50 ethylene oxide groups and 16~18 carbon atoms in hydrophobic alkyl chain.

• Korean Journal of Optics and Photonics
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• v.34 no.4
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• pp.157-169
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• 2023

Augmented reality (AR) using a head mounted display (HMD) is used in various fields such as military, medicine, manufacturing, gaming, and education. In this paper, we discuss the design and fabrication of the AR optical system, which is most essential for HMD. The AR optical system for HMD requires a wide transparent area in which the augmented image of the display and the real world can be viewed at the same time. To this end, an AR optical system was designed and manufactured by dividing it into three parts according to each characteristic. Also, the refractive index of the ultra-violet (UV) adhesive layer required to make the three optical systems into one complete AR optical system was considered from the design stage to minimize the optical path shift phenomenon when the input light source passes through the UV adhesive layer. In addition, when designing the AR optical system, two aspheric surfaces were used to compensate for off-axis aberration and to be suitable for mass production. Finally, for HMD mass production, an aspheric AR optical system with a thickness of 11 mm, a diagonal field of view of 40°, and a weight of 11.3 g was designed and manufactured.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.3
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• pp.88-98
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• 2011

Masonry structure is a style of building which has been widely applied as residential facilities of low and middle stories, commercial and public facilities etc. But it is possible to destroy by loss of adhesive strength or sliding when lateral forces, such as earthquake, occurs. This study proposes a seismic retrofit method for masonry structure and its seismic performance is demonstrated by shaking table test. Two specimens per each shaking direction were made, having out-of-plane(weak axis) and in-plane(strong axis) direction. External load of 1 ton was also applied for each specimen during the test, to model the behavior of reinforced masonry wall. As a result of shaking table tests, it is shown that the specimen applying the proposed seismic retrofit method showed acceptable behaviors in both of Korea building design criteria(0.14g) and USA seismic criteria suggested by IBC(0.4g). However, it was observed that stiffness of the specimen toward out-of-plane was rapidly decreasing when seismic excitations over 0.14g were loaded. In comparison of relative displacements, maximum relative displacement of specimens which were accelerated toward out-of-plane with 0.4g at once was 29~31% of maximum relative displacement when specimens were gradually accelerated from 0.08g to 0.4g, while the maximum relative displacement of specimens accelerated toward in-plane has similar value in both cases. Therefore, it is concluded that the wall accelerated toward out-of-plane is more affected by hair crack or possible fatigues caused by seismic excitation.